Tyrosine 687 phosphorylated Alzheimer's amyloid precursor protein is retained intracellularly and exhibits a decreased turnover rate

Neurodegenerative Diseases

Volumn 4, Issue 2-3, 2007, Pages 78-87

  Rebelo, Sandra ^a   Vieira, Sandra Isabel ^a   Esselmann, Hermann ^b   Wiltfang, Jens ^b   Da Cruz E Silva, Edgar F ^a   Da Cruz E Silva, Odete A B ^a  

^a UNIVERSITY OF AVEIRO   (Portugal)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Abeta; Amyloid precursor protein phosphorylation; Amyloid precursor protein GFP fusion; Subcellular amyloid precursor protein targeting; Tyrosine 687

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CELL PROTEIN; GREEN FLUORESCENT PROTEIN; MUTANT PROTEIN; TYROSINE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL CULTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HALF LIFE TIME; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; REGULATORY MECHANISM; TRANS GOLGI NETWORK;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CALNEXIN; CERCOPITHECUS AETHIOPS; COS CELLS; CYCLOHEXIMIDE; GENE EXPRESSION; GREEN FLUORESCENT PROTEINS; HUMANS; PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITORS; QA-SNARE PROTEINS; SUBCELLULAR FRACTIONS; TIME FACTORS; TRANSFECTION; TYROSINE;

EID: 34347256728     PISSN: 16602854     EISSN: 16602862     Source Type: Journal    
DOI: 10.1159/000101831     Document Type: Article

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