메뉴 건너뛰기




Volumn 21, Issue 7, 2007, Pages 581-609

Duloxetine: A review of its use in the treatment of major depressive disorder

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; ASPARTATE AMINOTRANSFERASE; CYTOCHROME P450 1A2; CYTOCHROME P450 2D6; DOPAMINE 2 RECEPTOR; DOPAMINE TRANSPORTER; DULOXETINE; ESCITALOPRAM; FLUOXETINE; HISTAMINE H1 RECEPTOR; LORAZEPAM; MILNACIPRAN; MOXIFLOXACIN; MUSCARINIC RECEPTOR; NORADRENALIN TRANSPORTER; OPIATE RECEPTOR; PAROXETINE; PLACEBO; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN RECEPTOR; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TEMAZEPAM; THEOPHYLLINE; UNINDEXED DRUG; VENLAFAXINE; ZOPICLONE;

EID: 34347238257     PISSN: 11727047     EISSN: None     Source Type: Journal    
DOI: 10.2165/00023210-200721070-00004     Document Type: Review
Times cited : (62)

References (124)
  • 1
    • 18844370877 scopus 로고    scopus 로고
    • The dual transporter inhibitor duloxetine: A review of its preclinical pharmacology, pharmacokinetic profile, and clinical results in depression
    • Bymaster FP, Lee TC, Knadler MP, et al. The dual transporter inhibitor duloxetine: a review of its preclinical pharmacology, pharmacokinetic profile, and clinical results in depression. Curr Pharm Des 2005; 11 (12): 1475-93
    • (2005) Curr Pharm Des , vol.11 , Issue.12 , pp. 1475-1493
    • Bymaster, F.P.1    Lee, T.C.2    Knadler, M.P.3
  • 2
    • 34347243127 scopus 로고    scopus 로고
    • Cymbalta 30mg hard gastro-resistant capsules, Cymbalta 60mg hard gastro-resistant capsules: summary of product characteristics. Basingstoke: Eli Lilly and Company Limited, 2006 Dec 17
    • Cymbalta 30mg hard gastro-resistant capsules, Cymbalta 60mg hard gastro-resistant capsules: summary of product characteristics. Basingstoke: Eli Lilly and Company Limited, 2006 Dec 17
  • 3
    • 34347251165 scopus 로고    scopus 로고
    • Cymbalta® (duloxetine hydrochloride) delayed-release capsules prescribing information. Indianapolis (IN): Eli Lilly and Company, 2007
    • Cymbalta® (duloxetine hydrochloride) delayed-release capsules prescribing information. Indianapolis (IN): Eli Lilly and Company, 2007
  • 4
    • 34347237780 scopus 로고    scopus 로고
    • Yentreve 20mg and 40mg hard gastro-resistant capsules: summary of product characteristics. Eli Lilly and Company Limited, 2007 Jan 17
    • Yentreve 20mg and 40mg hard gastro-resistant capsules: summary of product characteristics. Eli Lilly and Company Limited, 2007 Jan 17
  • 5
    • 26644462876 scopus 로고    scopus 로고
    • SNRIs: Their pharmacology, clinical efficacy, and tolerability in comparison with other classes of antidepressants
    • Aug;
    • Stahl SM, Grady MM, Moret C, et al. SNRIs: their pharmacology, clinical efficacy, and tolerability in comparison with other classes of antidepressants. CNS Spectr 2005 Aug; 10 (9): 732-47
    • (2005) CNS Spectr , vol.10 , Issue.9 , pp. 732-747
    • Stahl, S.M.1    Grady, M.M.2    Moret, C.3
  • 6
    • 33644904607 scopus 로고    scopus 로고
    • Duloxetine: A new selective and dual-acting antidepressant
    • Mar;
    • Bauer M, Moller HJ, Schneider E. Duloxetine: a new selective and dual-acting antidepressant. Expert Opin Pharmacother 2006 Mar; 7 (4): 421-7
    • (2006) Expert Opin Pharmacother , vol.7 , Issue.4 , pp. 421-427
    • Bauer, M.1    Moller, H.J.2    Schneider, E.3
  • 7
    • 27244437919 scopus 로고    scopus 로고
    • Mann JJ. The medical management of depression. N Engl J Med 2005 Oct 27; 353 (17): 1819-34
    • Mann JJ. The medical management of depression. N Engl J Med 2005 Oct 27; 353 (17): 1819-34
  • 8
    • 0037311073 scopus 로고    scopus 로고
    • Dual monoamine modulation for improved treatment of major depressive disorder
    • Feb;
    • Tran PV, Bymaster FP, McNamara RK, et al. Dual monoamine modulation for improved treatment of major depressive disorder. J Clin Psychopharmacol 2003 Feb; 23 (1): 78-86
    • (2003) J Clin Psychopharmacol , vol.23 , Issue.1 , pp. 78-86
    • Tran, P.V.1    Bymaster, F.P.2    McNamara, R.K.3
  • 9
    • 0031884423 scopus 로고    scopus 로고
    • Specific serotonin and noradrenaline reuptake inhibitors (SNRIs): A review of their pharmacology, clinical efficacy and tolerability
    • Briley M. Specific serotonin and noradrenaline reuptake inhibitors (SNRIs): a review of their pharmacology, clinical efficacy and tolerability. Hum Psychopharmacol 1998; 13 (2): 99-111
    • (1998) Hum Psychopharmacol , vol.13 , Issue.2 , pp. 99-111
    • Briley, M.1
  • 10
    • 0027475388 scopus 로고
    • LY248686, a new inhibitor of serotonin and norepinephrine uptake
    • Jan;
    • Wong DT, Bymaster FP, Mayle DA, et al. LY248686, a new inhibitor of serotonin and norepinephrine uptake. Neuropsychopharmacology 1993 Jan; 8 (1): 23-33
    • (1993) Neuropsychopharmacology , vol.8 , Issue.1 , pp. 23-33
    • Wong, D.T.1    Bymaster, F.P.2    Mayle, D.A.3
  • 11
    • 0035677108 scopus 로고    scopus 로고
    • Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors
    • Dec;
    • Bymaster FP, Dreshfield-Ahmad LJ, Threlkeld PG, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology 2001 Dec; 25 (6): 871-80
    • (2001) Neuropsychopharmacology , vol.25 , Issue.6 , pp. 871-880
    • Bymaster, F.P.1    Dreshfield-Ahmad, L.J.2    Threlkeld, P.G.3
  • 12
    • 0036963804 scopus 로고    scopus 로고
    • Duloxetine pharmacology: Profile of a dual monoamine modulator
    • Winter;
    • Karpa KD, Cavanaugh JE, Lakoski JM. Duloxetine pharmacology: profile of a dual monoamine modulator. CNS Drug Rev 2002 Winter; 8 (4): 361-76
    • (2002) CNS Drug Rev , vol.8 , Issue.4 , pp. 361-376
    • Karpa, K.D.1    Cavanaugh, J.E.2    Lakoski, J.M.3
  • 13
    • 0031931974 scopus 로고    scopus 로고
    • Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test
    • Mar;
    • Reneric JP, Lucki I. Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test. Psychopharmacology (Berl) 1998 Mar; 136 (2): 190-7
    • (1998) Psychopharmacology (Berl) , vol.136 , Issue.2 , pp. 190-197
    • Reneric, J.P.1    Lucki, I.2
  • 14
    • 0028935452 scopus 로고
    • Behavioral and electroencephalographic properties of duloxetine (LY248686), a reuptake inhibitor of norepinephrine and serotonin, in mice and rats
    • Mar;
    • Katoh A, Eigyo M, Ishibashi C, et al. Behavioral and electroencephalographic properties of duloxetine (LY248686), a reuptake inhibitor of norepinephrine and serotonin, in mice and rats. J Pharmacol Exp Ther 1995 Mar; 272 (3): 1067-75
    • (1995) J Pharmacol Exp Ther , vol.272 , Issue.3 , pp. 1067-1075
    • Katoh, A.1    Eigyo, M.2    Ishibashi, C.3
  • 15
    • 6344237788 scopus 로고    scopus 로고
    • Efficacy of the selective serotonin and norepinephrine reuptake inhibitor, duloxetine, in the formalin model of persistent pain [abstract]
    • Jun;
    • Iyengar S, Bymaster FP, Wong DT, et al. Efficacy of the selective serotonin and norepinephrine reuptake inhibitor, duloxetine, in the formalin model of persistent pain [abstract]. Pain Med 2002 Jun; 3 (2): 177
    • (2002) Pain Med , vol.3 , Issue.2 , pp. 177
    • Iyengar, S.1    Bymaster, F.P.2    Wong, D.T.3
  • 16
    • 0035079542 scopus 로고    scopus 로고
    • Assessment of the serotonin and norepinephrine reuptake blocking properties of duloxetine in healthy subjects
    • May;
    • Turcotte JE, Debonnel G, de Montigny C, et al. Assessment of the serotonin and norepinephrine reuptake blocking properties of duloxetine in healthy subjects. Neuropsychopharmacology 2001 May; 24 (5): 511-21
    • (2001) Neuropsychopharmacology , vol.24 , Issue.5 , pp. 511-521
    • Turcotte, J.E.1    Debonnel, G.2    de Montigny, C.3
  • 17
    • 0141781033 scopus 로고    scopus 로고
    • Duloxetine increases serotonin and norepinephrine availability in healthy subjects: A double-blind, controlled study
    • Sep;
    • Chalon SA, Granier LA, Vandenhende FR, et al. Duloxetine increases serotonin and norepinephrine availability in healthy subjects: a double-blind, controlled study. Neuropsychopharmacology 2003 Sep; 28 (9): 1685-93
    • (2003) Neuropsychopharmacology , vol.28 , Issue.9 , pp. 1685-1693
    • Chalon, S.A.1    Granier, L.A.2    Vandenhende, F.R.3
  • 18
    • 4444224449 scopus 로고    scopus 로고
    • Clinical assessment of norepinephrine transporter blockade through biochemical and pharmacological profiles
    • Jun 29;
    • Vincent S, Bieck PR, Garland EM, et al. Clinical assessment of norepinephrine transporter blockade through biochemical and pharmacological profiles. Circulation 2004 Jun 29; 109 (25): 3202-7
    • (2004) Circulation , vol.109 , Issue.25 , pp. 3202-3207
    • Vincent, S.1    Bieck, P.R.2    Garland, E.M.3
  • 19
    • 25844501365 scopus 로고    scopus 로고
    • Duloxetine hydrochloride: A new dual-acting medication for the treatment of major depressive disorder
    • Aug;
    • Hunziker ME, Suehs BT, Bettinger TL, et al. Duloxetine hydrochloride: a new dual-acting medication for the treatment of major depressive disorder. Clin Ther 2005 Aug; 27 (8): 1126-43
    • (2005) Clin Ther , vol.27 , Issue.8 , pp. 1126-1143
    • Hunziker, M.E.1    Suehs, B.T.2    Bettinger, T.L.3
  • 20
    • 15444376068 scopus 로고    scopus 로고
    • Cardiovascular profile of duloxetine, a dual reuptake inhibitor of serotonin and norepinephrine
    • Apr;
    • Thase ME, Tran PV, Wiltse C, et al. Cardiovascular profile of duloxetine, a dual reuptake inhibitor of serotonin and norepinephrine. J Clin Psychopharmacol 2005 Apr; 25 (2): 132-40
    • (2005) J Clin Psychopharmacol , vol.25 , Issue.2 , pp. 132-140
    • Thase, M.E.1    Tran, P.V.2    Wiltse, C.3
  • 21
    • 0036200457 scopus 로고    scopus 로고
    • The tyramine pressor test may have limited sensitivity, especially in the presence of dual serotonin/norepinephrine uptake inhibition [letter]
    • Chalon S, Bieck PR, Goldstein DJ, et al. The tyramine pressor test may have limited sensitivity, especially in the presence of dual serotonin/norepinephrine uptake inhibition [letter]. Neuropsychopharmacology 2002; 26 (5): 698-701
    • (2002) Neuropsychopharmacology , vol.26 , Issue.5 , pp. 698-701
    • Chalon, S.1    Bieck, P.R.2    Goldstein, D.J.3
  • 22
    • 0141600340 scopus 로고    scopus 로고
    • Duloxetine affects sleep architecture with antidepressant like pattern [abstract no. PII-65]
    • Feb;
    • Chalon S, Granier LA, Vandenhende F, et al. Duloxetine affects sleep architecture with antidepressant like pattern [abstract no. PII-65]. Clin Pharmacol Ther 2001 Feb; 69: P49
    • (2001) Clin Pharmacol Ther , vol.69
    • Chalon, S.1    Granier, L.A.2    Vandenhende, F.3
  • 23
    • 34248512526 scopus 로고    scopus 로고
    • Duloxetine increases stage 3 sleep and suppresses rapid eye movement (REM) sleep in patients with major depression
    • Kluge M, Schussler P, Steiger A. Duloxetine increases stage 3 sleep and suppresses rapid eye movement (REM) sleep in patients with major depression. Eur Neuropsychopharmacol 2007; 17 (8): 527-31
    • (2007) Eur Neuropsychopharmacol , vol.17 , Issue.8 , pp. 527-531
    • Kluge, M.1    Schussler, P.2    Steiger, A.3
  • 24
    • 0033674519 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of duloxetine, a dual-serotonin and norepinephrine reuptake inhibitor
    • Feb;
    • Sharma A, Goldberg MJ, Cerimele BJ. Pharmacokinetics and safety of duloxetine, a dual-serotonin and norepinephrine reuptake inhibitor. J Clin Pharmacol 2000 Feb; 40 (2): 161-7
    • (2000) J Clin Pharmacol , vol.40 , Issue.2 , pp. 161-167
    • Sharma, A.1    Goldberg, M.J.2    Cerimele, B.J.3
  • 25
    • 9744221402 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of duloxetine, a potential new antidepressant with serotonin and norepinephrine uptake inhibition [abstract no. P.1.043]
    • Sep;
    • Granier L-A, Vandenhende F, de Suray JM. Safety and pharmacokinetics of duloxetine, a potential new antidepressant with serotonin and norepinephrine uptake inhibition [abstract no. P.1.043]. Eur Neuropsychopharmacol 1999 Sep; 9 Suppl. 5: 222
    • (1999) Eur Neuropsychopharmacol , vol.9 , Issue.SUPPL. 5 , pp. 222
    • Granier, L.-A.1    Vandenhende, F.2    de Suray, J.M.3
  • 26
    • 0002471005 scopus 로고    scopus 로고
    • The effect of food and bedtime administration on duloxetine pharmacokinetics [abstract no. PII-59]
    • Feb;
    • Skinner MH, Skerjanec A, Seger M, et al. The effect of food and bedtime administration on duloxetine pharmacokinetics [abstract no. PII-59]. Clin Pharmacol Ther 2000 Feb; 67: 129
    • (2000) Clin Pharmacol Ther , vol.67 , pp. 129
    • Skinner, M.H.1    Skerjanec, A.2    Seger, M.3
  • 27
    • 0041856533 scopus 로고    scopus 로고
    • Metabolism, excretion, and pharmacokinetics of duloxetine in healthy human subjects
    • Sep;
    • Lantz RJ, Gillespie TA, Rash TJ, et al. Metabolism, excretion, and pharmacokinetics of duloxetine in healthy human subjects. Drug Metab Dispos 2003 Sep; 31 (9): 1142-50
    • (2003) Drug Metab Dispos , vol.31 , Issue.9 , pp. 1142-1150
    • Lantz, R.J.1    Gillespie, T.A.2    Rash, T.J.3
  • 28
    • 14544275911 scopus 로고    scopus 로고
    • Duloxetine pharmacokinetics in cirrhotics compared with healthy subjects
    • Feb;
    • Suri A, Reddy S, Gonzales C, et al. Duloxetine pharmacokinetics in cirrhotics compared with healthy subjects. Int J Clin Pharmacol Ther 2005 Feb; 43 (2): 78-84
    • (2005) Int J Clin Pharmacol Ther , vol.43 , Issue.2 , pp. 78-84
    • Suri, A.1    Reddy, S.2    Gonzales, C.3
  • 29
    • 2942594466 scopus 로고    scopus 로고
    • Synthesis and biological activity of some known and putative duloxetine metabolites
    • Jul 5;
    • Kuo F, Gillespie TA, Kulanthaivel P, et al. Synthesis and biological activity of some known and putative duloxetine metabolites. Bioorg Med Chem Lett 2004 Jul 5; 14 (13): 3481-6
    • (2004) Bioorg Med Chem Lett , vol.14 , Issue.13 , pp. 3481-3486
    • Kuo, F.1    Gillespie, T.A.2    Kulanthaivel, P.3
  • 30
    • 0038186563 scopus 로고    scopus 로고
    • Effect of duloxetine on CYP1A2-mediated drug metabolism and the pharmacokinetics of theophylline [abstract no. TPII-78]
    • Feb;
    • di Virgilio SN, Gonzales C, Knadler MP, et al. Effect of duloxetine on CYP1A2-mediated drug metabolism and the pharmacokinetics of theophylline [abstract no. TPII-78]. Clin Pharmacol Ther 2002 Feb; 71: 63
    • (2002) Clin Pharmacol Ther , vol.71 , pp. 63
    • di Virgilio, S.N.1    Gonzales, C.2    Knadler, M.P.3
  • 31
    • 0037374043 scopus 로고    scopus 로고
    • Duloxetine is both an inhibitor and a substrate of cytochrome P4502D6 in healthy volunteers
    • Mar;
    • Skinner MH, Kuan HY, Pan A, et al. Duloxetine is both an inhibitor and a substrate of cytochrome P4502D6 in healthy volunteers. Clin Pharmacol Ther 2003 Mar; 73 (3): 170-7
    • (2003) Clin Pharmacol Ther , vol.73 , Issue.3 , pp. 170-177
    • Skinner, M.H.1    Kuan, H.Y.2    Pan, A.3
  • 32
    • 33846210546 scopus 로고    scopus 로고
    • Comparison of duloxetine, escitalopram, and sertraline effects on cytochrome P450 2D6 function in healthy volunteers
    • Feb;
    • Preskorn SH, Greenblatt DJ, Flockhart D, et al. Comparison of duloxetine, escitalopram, and sertraline effects on cytochrome P450 2D6 function in healthy volunteers. J Clin Psychopharmacol 2007 Feb; 27 (1): 28-34
    • (2007) J Clin Psychopharmacol , vol.27 , Issue.1 , pp. 28-34
    • Preskorn, S.H.1    Greenblatt, D.J.2    Flockhart, D.3
  • 33
    • 0347319049 scopus 로고    scopus 로고
    • Effect of age on the pharmacokinetics of duloxetine in women
    • Jan;
    • Skinner MH, Kuan HY, Skerjanec A, et al. Effect of age on the pharmacokinetics of duloxetine in women. Br J Clin Pharmacol 2004 Jan; 57 (1): 54-61
    • (2004) Br J Clin Pharmacol , vol.57 , Issue.1 , pp. 54-61
    • Skinner, M.H.1    Kuan, H.Y.2    Skerjanec, A.3
  • 34
    • 34347208641 scopus 로고    scopus 로고
    • Combined administration of duloxetine and lorazepam: A pharmacokinetic and pharmacodynamic study [abstract no. PII-56]
    • Feb;
    • Chalon S, Vandenhende F, Ertle S. Combined administration of duloxetine and lorazepam: a pharmacokinetic and pharmacodynamic study [abstract no. PII-56]. Clin Pharmacol Ther 2005 Feb; 77 (2): 65
    • (2005) Clin Pharmacol Ther , vol.77 , Issue.2 , pp. 65
    • Chalon, S.1    Vandenhende, F.2    Ertle, S.3
  • 35
    • 0037848857 scopus 로고    scopus 로고
    • Duloxetine does not exacerbate the effects of alcohol on psychometric tests [abstract no. TPII-45]
    • Feb;
    • Skinner MH, Weerakkody G. Duloxetine does not exacerbate the effects of alcohol on psychometric tests [abstract no. TPII-45]. Clin Pharmacol Ther 2002 Feb; 71: 53
    • (2002) Clin Pharmacol Ther , vol.71 , pp. 53
    • Skinner, M.H.1    Weerakkody, G.2
  • 36
    • 33645500817 scopus 로고    scopus 로고
    • Interaction of duloxetine and warfarin causing severe elevation of international normalized ratio
    • Apr 5;
    • Glueck CJ, Khalil Q, Winiarska M, et al. Interaction of duloxetine and warfarin causing severe elevation of international normalized ratio. JAMA 2006 Apr 5; 295 (13): 1517-8
    • (2006) JAMA , vol.295 , Issue.13 , pp. 1517-1518
    • Glueck, C.J.1    Khalil, Q.2    Winiarska, M.3
  • 37
    • 33846957159 scopus 로고    scopus 로고
    • Duloxetine pharmacokinetics are similar in Japanese and Caucasian subjects
    • Mar;
    • Chan C, Yeo KP, Pan AX, et al. Duloxetine pharmacokinetics are similar in Japanese and Caucasian subjects. Br J Clin Pharmacol 2007 Mar; 63 (3): 310-4
    • (2007) Br J Clin Pharmacol , vol.63 , Issue.3 , pp. 310-314
    • Chan, C.1    Yeo, K.P.2    Pan, A.X.3
  • 38
    • 0036232639 scopus 로고    scopus 로고
    • Duloxetine, 60mg once daily, for major depressive disorder: A randomized double-blind placebo-controlled trial
    • Apr;
    • Detke MJ, Lu Y, Goldstein DJ, et al. Duloxetine, 60mg once daily, for major depressive disorder: a randomized double-blind placebo-controlled trial. J Clin Psychiatry 2002 Apr; 63 (4): 308-15
    • (2002) J Clin Psychiatry , vol.63 , Issue.4 , pp. 308-315
    • Detke, M.J.1    Lu, Y.2    Goldstein, D.J.3
  • 39
    • 0036829053 scopus 로고    scopus 로고
    • Duloxetine 60 mg once daily dosing versus placebo in the acute treatment of major depression
    • Detke MJ, Lu Y, Goldstein DJ, et al. Duloxetine 60 mg once daily dosing versus placebo in the acute treatment of major depression. J Psychiatr Res 2002; 36 (6): 383-90
    • (2002) J Psychiatr Res , vol.36 , Issue.6 , pp. 383-390
    • Detke, M.J.1    Lu, Y.2    Goldstein, D.J.3
  • 40
    • 0036112313 scopus 로고    scopus 로고
    • Duloxetine in the treatment of major depressive disorder: A double-blind clinical trial
    • Mar;
    • Goldstein DJ, Mallinckrodt C, Lu Y, et al. Duloxetine in the treatment of major depressive disorder: a double-blind clinical trial. J Clin Psychiatry 2002 Mar; 63 (3): 225-31
    • (2002) J Clin Psychiatry , vol.63 , Issue.3 , pp. 225-231
    • Goldstein, D.J.1    Mallinckrodt, C.2    Lu, Y.3
  • 41
    • 3242707697 scopus 로고    scopus 로고
    • Duloxetine in the treatment of depression: A double-blind placebo-controlled comparison with paroxetine
    • Aug;
    • Goldstein DJ, Lu Y, Detke MJ, et al. Duloxetine in the treatment of depression: a double-blind placebo-controlled comparison with paroxetine. J Clin Psychopharmacol 2004 Aug; 24 (4): 389-99
    • (2004) J Clin Psychopharmacol , vol.24 , Issue.4 , pp. 389-399
    • Goldstein, D.J.1    Lu, Y.2    Detke, M.J.3
  • 42
    • 10344219954 scopus 로고    scopus 로고
    • Duloxetine in the acute and long-term treatment of major depressive disorder: A placebo- and paroxetine-controlled trial
    • Dec;
    • Detke MJ, Wiltse CG, Mallinckrodt CH, et al. Duloxetine in the acute and long-term treatment of major depressive disorder: a placebo- and paroxetine-controlled trial. Eur Neuropsychopharmacol 2004 Dec; 14 (6): 457-70
    • (2004) Eur Neuropsychopharmacol , vol.14 , Issue.6 , pp. 457-470
    • Detke, M.J.1    Wiltse, C.G.2    Mallinckrodt, C.H.3
  • 43
    • 33748688471 scopus 로고    scopus 로고
    • Duloxetine in the treatment of major depressive disorder: A placebo- and paroxetine-controlled trial
    • May 10;
    • Perahia DG, Wang F, Mallinckrodt CH, et al. Duloxetine in the treatment of major depressive disorder: a placebo- and paroxetine-controlled trial. Eur Psychiatry 2006 May 10; 21 (6): 367-78
    • (2006) Eur Psychiatry , vol.21 , Issue.6 , pp. 367-378
    • Perahia, D.G.1    Wang, F.2    Mallinckrodt, C.H.3
  • 44
    • 7044229576 scopus 로고    scopus 로고
    • Duloxetine 60mg once-daily in the treatment of painful physical symptoms in patients with major depressive disorder
    • Jan;
    • Brannan SK, Mallinckrodt CH, Brown EB, et al. Duloxetine 60mg once-daily in the treatment of painful physical symptoms in patients with major depressive disorder. J Psychiatr Res 2005 Jan; 39 (1): 43-53
    • (2005) J Psychiatr Res , vol.39 , Issue.1 , pp. 43-53
    • Brannan, S.K.1    Mallinckrodt, C.H.2    Brown, E.B.3
  • 45
    • 33645654076 scopus 로고    scopus 로고
    • Duloxetine in the prevention of relapse of major depressive disorder
    • Apr;
    • Perahia DG, Gilaberte I, Wang F, et al. Duloxetine in the prevention of relapse of major depressive disorder. Br J Psychiatry 2006 Apr; 188: 346-53
    • (2006) Br J Psychiatry , vol.188 , pp. 346-353
    • Perahia, D.G.1    Gilaberte, I.2    Wang, F.3
  • 46
    • 33646383578 scopus 로고    scopus 로고
    • Management of depression relapse: Re-initiation of duloxetine treatment or dose increase
    • Jun;
    • Fava M, Detke MJ, Balestrieri M, et al. Management of depression relapse: re-initiation of duloxetine treatment or dose increase. J Psychiatr Res 2006 Jun; 40 (4): 328-36
    • (2006) J Psychiatr Res , vol.40 , Issue.4 , pp. 328-336
    • Fava, M.1    Detke, M.J.2    Balestrieri, M.3
  • 47
    • 1842515339 scopus 로고    scopus 로고
    • Duloxetine in the long-term treatment of major depressive disorder
    • Oct;
    • Raskin J, Goldstein DJ, Mallinckrodt CH, et al. Duloxetine in the long-term treatment of major depressive disorder. J Clin Psychiatry 2003 Oct; 64 (10): 1237-44
    • (2003) J Clin Psychiatry , vol.64 , Issue.10 , pp. 1237-1244
    • Raskin, J.1    Goldstein, D.J.2    Mallinckrodt, C.H.3
  • 48
    • 34250380365 scopus 로고    scopus 로고
    • Double-blind comparison of escitalopram and duloxetine in the acute treatment of major depressive disorder
    • Khan A, Bose A, Alexopoulos GS, et al. Double-blind comparison of escitalopram and duloxetine in the acute treatment of major depressive disorder. Clin Drug Invest 2007; 27 (7): 481-192
    • (2007) Clin Drug Invest , vol.27 , Issue.7 , pp. 481-192
    • Khan, A.1    Bose, A.2    Alexopoulos, G.S.3
  • 49
    • 33847413286 scopus 로고    scopus 로고
    • Duloxetine versus escitalopram and placebo in the treatment of patients with major depressive disorder: Onset of antidepressant action, a non-inferiority study
    • Feb;
    • Nierenberg AA, Greist JH, Mallinckrodt CH, et al. Duloxetine versus escitalopram and placebo in the treatment of patients with major depressive disorder: onset of antidepressant action, a non-inferiority study. Curr Med Res Opin 2007 Feb; 23 (2): 401-16
    • (2007) Curr Med Res Opin , vol.23 , Issue.2 , pp. 401-416
    • Nierenberg, A.A.1    Greist, J.H.2    Mallinckrodt, C.H.3
  • 50
    • 34347241658 scopus 로고    scopus 로고
    • A comparative study of the efficacy of acute and continuation treatment with escitalopram versus duloxetine in patients with major depressive disorder
    • Wade A, Gembert K, Florea I, et al. A comparative study of the efficacy of acute and continuation treatment with escitalopram versus duloxetine in patients with major depressive disorder. Curr Med Res Opin 2007; 23 (7): 1605-14
    • (2007) Curr Med Res Opin , vol.23 , Issue.7 , pp. 1605-1614
    • Wade, A.1    Gembert, K.2    Florea, I.3
  • 52
    • 34250832737 scopus 로고    scopus 로고
    • Efficacy of duloxetine on cognition, depression, and pain in elderly patients with major depressive disorder
    • Raskin J, Wiltse CG, Siegal A, et al. Efficacy of duloxetine on cognition, depression, and pain in elderly patients with major depressive disorder. Am J Psychiatry 2007; 164: 900-9
    • (2007) Am J Psychiatry , vol.164 , pp. 900-909
    • Raskin, J.1    Wiltse, C.G.2    Siegal, A.3
  • 53
    • 34347230453 scopus 로고    scopus 로고
    • Efficacy of duloxetine in the treatment of unspecified pain associated with depression
    • Mar 17-21; Madrid
    • Brecht S, Courtecuisse C, Debieuvre C, et al. Efficacy of duloxetine in the treatment of unspecified pain associated with depression. 15th European Congress of Psychiatry; 2007 Mar 17-21; Madrid
    • (2007) 15th European Congress of Psychiatry
    • Brecht, S.1    Courtecuisse, C.2    Debieuvre, C.3
  • 54
    • 34347220843 scopus 로고    scopus 로고
    • Eli Lilly and Company. Clinical study summary: Study F1J-MC-HMAT Study Group A [online]. Available from URL: http://www.lillytrials.com/results_files/ cymbalta/cymbalta_summary_4091a.pdf [Accessed 2007 Jan 9]
    • Eli Lilly and Company. Clinical study summary: Study F1J-MC-HMAT Study Group A [online]. Available from URL: http://www.lillytrials.com/results_files/ cymbalta/cymbalta_summary_4091a.pdf [Accessed 2007 Jan 9]
  • 55
    • 34347247619 scopus 로고    scopus 로고
    • Eli Lilly and Company. Clinical study summary: Study F1J-MC-HMAQ Study Group B [online]. Available from URL: http://www.lillytrials.com/results_files/ cymbalta/cymbalta_summary_3327b.pdf [Accessed 2007 Jan 9]
    • Eli Lilly and Company. Clinical study summary: Study F1J-MC-HMAQ Study Group B [online]. Available from URL: http://www.lillytrials.com/results_files/ cymbalta/cymbalta_summary_3327b.pdf [Accessed 2007 Jan 9]
  • 56
    • 84965188482 scopus 로고    scopus 로고
    • Duloxetine for the treatment of major depressive disorder
    • Autumn;
    • Nemeroff CB, Schatzberg AF, Goldstein DJ, et al. Duloxetine for the treatment of major depressive disorder. Psychopharmacol Bull 2002 Autumn; 36 (4): 106-32
    • (2002) Psychopharmacol Bull , vol.36 , Issue.4 , pp. 106-132
    • Nemeroff, C.B.1    Schatzberg, A.F.2    Goldstein, D.J.3
  • 57
    • 34347254954 scopus 로고    scopus 로고
    • Eli Lilly and Company clinical trial registry [online]. Available from URL: http://lillytrials.com/ [Accessed 2007 Jan 21]
    • Eli Lilly and Company clinical trial registry [online]. Available from URL: http://lillytrials.com/ [Accessed 2007 Jan 21]
  • 58
    • 33749516613 scopus 로고    scopus 로고
    • Effects of the antidepressant duloxetine on body weight: Analyses of 10 clinical studies
    • Wise TN, Perahia DG, Pangallo BA, et al. Effects of the antidepressant duloxetine on body weight: analyses of 10 clinical studies. Prim Care Companion J Clin Psychiatry 2006; 8 (5): 269-78
    • (2006) Prim Care Companion J Clin Psychiatry , vol.8 , Issue.5 , pp. 269-278
    • Wise, T.N.1    Perahia, D.G.2    Pangallo, B.A.3
  • 59
    • 34347271628 scopus 로고    scopus 로고
    • Duloxetine versus escitalopram and placebo in the long-term treatment of patients with MDD
    • abstract no. 13, May 20-25; Toronto ON
    • Pigott TA, Arnold LM, Aaronson ST, et al. Duloxetine versus escitalopram and placebo in the long-term treatment of patients with MDD [abstract no. 13]. 159th Annual Meeting of the American Psychiatric Association; 2006 May 20-25; Toronto (ON), 73
    • (2006) 159th Annual Meeting of the American Psychiatric Association , pp. 73
    • Pigott, T.A.1    Arnold, L.M.2    Aaronson, S.T.3
  • 60
    • 0004235298 scopus 로고
    • American Psychiatric Association, 4th ed. Washington DC: American Psychiatric Association
    • American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. Washington DC: American Psychiatric Association, 1994
    • (1994) Diagnostic and statistical manual of mental disorders
  • 61
    • 12944268752 scopus 로고    scopus 로고
    • The efficacy of duloxetine: A comprehensive summary of results from MMRM and LOCF_ANCOVA in eight clinical trials
    • Sep 8;
    • Mallinckrodt CH, Raskin J, Wohlreich MM, et al. The efficacy of duloxetine: a comprehensive summary of results from MMRM and LOCF_ANCOVA in eight clinical trials. BMC Psychiatry 2004 Sep 8; 4 (26)
    • (2004) BMC Psychiatry , vol.4 , Issue.26
    • Mallinckrodt, C.H.1    Raskin, J.2    Wohlreich, M.M.3
  • 62
    • 33646336858 scopus 로고    scopus 로고
    • Duloxetine for the treatment of major depressive disorder: A closer look at efficacy and safety data across the approved dose range
    • Mallinckrodt CH, Prakash A, Andorn AC, et al. Duloxetine for the treatment of major depressive disorder: a closer look at efficacy and safety data across the approved dose range. J Psychiatr Res 2006; 40: 337-48
    • (2006) J Psychiatr Res , vol.40 , pp. 337-348
    • Mallinckrodt, C.H.1    Prakash, A.2    Andorn, A.C.3
  • 63
    • 10044297400 scopus 로고    scopus 로고
    • Onset of action for duloxetine 60mg once daily: Double-blind, placebo-controlled studies
    • Mar;
    • Brannan SK, Mallinckrodt CH, Detke MJ, et al. Onset of action for duloxetine 60mg once daily: double-blind, placebo-controlled studies. J Psychiatr Res 2005 Mar; 39 (2): 161-72
    • (2005) J Psychiatr Res , vol.39 , Issue.2 , pp. 161-172
    • Brannan, S.K.1    Mallinckrodt, C.H.2    Detke, M.J.3
  • 64
    • 2442625387 scopus 로고    scopus 로고
    • The effect of duloxetine on painful physical symptoms in depressed patients: Do improvements in these symptoms result in higher remission rates?
    • Apr;
    • Fava M, Mallinckrodt CH, Detke MJ, et al. The effect of duloxetine on painful physical symptoms in depressed patients: do improvements in these symptoms result in higher remission rates? J Clin Psychiatry 2004 Apr; 65 (4): 521-30
    • (2004) J Clin Psychiatry , vol.65 , Issue.4 , pp. 521-530
    • Fava, M.1    Mallinckrodt, C.H.2    Detke, M.J.3
  • 65
    • 33746762275 scopus 로고    scopus 로고
    • Duloxetine in the treatment of major depressive disorder: An assessment of the relationship between outcomes and episode characteristics
    • Sep;
    • Perahia DG, Kajdasz DK, Royer MG, et al. Duloxetine in the treatment of major depressive disorder: an assessment of the relationship between outcomes and episode characteristics. Int Clin Psychopharmacol 2006 Sep; 21 (5): 285-95
    • (2006) Int Clin Psychopharmacol , vol.21 , Issue.5 , pp. 285-295
    • Perahia, D.G.1    Kajdasz, D.K.2    Royer, M.G.3
  • 66
    • 33745428445 scopus 로고    scopus 로고
    • Duloxetine efficacy for major depressive disorder in male vs. female patients: Data from 7 randomized, double-blind, placebo-controlled trials
    • Kornstein SG, Wohlreich M, Mallinckrodt CH, et al. Duloxetine efficacy for major depressive disorder in male vs. female patients: data from 7 randomized, double-blind, placebo-controlled trials. J Clin Psychiatry 2006; 67: 761-70
    • (2006) J Clin Psychiatry , vol.67 , pp. 761-770
    • Kornstein, S.G.1    Wohlreich, M.2    Mallinckrodt, C.H.3
  • 67
    • 12944266749 scopus 로고    scopus 로고
    • Duloxetine in the treatment of major depressive disorder: A comparison of efficacy in patients with and without melancholic features
    • Mallinckrodt CH, Watkin JG, Liu C, et al. Duloxetine in the treatment of major depressive disorder: a comparison of efficacy in patients with and without melancholic features. BMC Psychiatry 2005; 5 (1)
    • (2005) BMC Psychiatry , vol.5 , Issue.1
    • Mallinckrodt, C.H.1    Watkin, J.G.2    Liu, C.3
  • 68
    • 33748671793 scopus 로고    scopus 로고
    • Dose-response relationship of duloxetine in placebo-controlled clinical trials in patients with major depressive disorder
    • Oct;
    • Bech P, Kajdasz DK, Porsdal V. Dose-response relationship of duloxetine in placebo-controlled clinical trials in patients with major depressive disorder. Psychopharmacology (Berl) 2006 Oct; 188 (3): 273-80
    • (2006) Psychopharmacology (Berl) , vol.188 , Issue.3 , pp. 273-280
    • Bech, P.1    Kajdasz, D.K.2    Porsdal, V.3
  • 69
    • 34347254569 scopus 로고    scopus 로고
    • Efficacy of duloxetine versus combined SSRIs (fluoxetine, paroxetine, escitalopram) and placebo in the treatment of MDD
    • abstract no. 228 plus poster, May 20-25; Toronto ON
    • Hirschfeld RMA, Mallinckrodt CH, Prakash A, et al. Efficacy of duloxetine versus combined SSRIs (fluoxetine, paroxetine, escitalopram) and placebo in the treatment of MDD [abstract no. 228 plus poster]. 159th Annual Meeting of the American Psychiatric Association; 2006 May 20-25; Toronto (ON), 95
    • (2006) 159th Annual Meeting of the American Psychiatric Association , pp. 95
    • Hirschfeld, R.M.A.1    Mallinckrodt, C.H.2    Prakash, A.3
  • 70
    • 34347270128 scopus 로고    scopus 로고
    • Efficacy of duloxetine vs. placebo in mild, moderate, and more severely ill patients with major depressive disorder
    • abstract no. NR270 plus poster, May 20-25; Toronto ON
    • Prakash A, Potts A, Shelton R, et al. Efficacy of duloxetine vs. placebo in mild, moderate, and more severely ill patients with major depressive disorder [abstract no. NR270 plus poster]. 159th Annual Meeting of the American Psychiatric Association; 2006 May 20-25; Toronto (ON)
    • (2006) 159th Annual Meeting of the American Psychiatric Association
    • Prakash, A.1    Potts, A.2    Shelton, R.3
  • 71
    • 34347232270 scopus 로고    scopus 로고
    • Efficacy of duloxetine versus placebo in mild, moderate, and more severely ill patients with major depressive disorder [abstract no. P38]
    • Dec 1;
    • Pum G. Efficacy of duloxetine versus placebo in mild, moderate, and more severely ill patients with major depressive disorder [abstract no. P38]. Int J Psychiatry Clin Pract 2006 Dec 1; 10 (4): 332
    • (2006) Int J Psychiatry Clin Pract , vol.10 , Issue.4 , pp. 332
    • Pum, G.1
  • 72
    • 34347264435 scopus 로고    scopus 로고
    • Efficacy of duloxetine versus SSRIs and placebo in treating major depressive disorders [abstract no. P37]
    • Dec 1;
    • Pum G. Efficacy of duloxetine versus SSRIs and placebo in treating major depressive disorders [abstract no. P37]. Int J Psychiatry Clin Pract 2006 Dec 1; 10 (4): 331-2
    • (2006) Int J Psychiatry Clin Pract , vol.10 , Issue.4 , pp. 331-332
    • Pum, G.1
  • 73
    • 4043142353 scopus 로고    scopus 로고
    • Efficacy of duloxetine treatment: Analysis of pooled data from six placebo- and SSRI-controlled clinical trials
    • abstract no. NR722 plus poster, May 1-5; New York NY
    • Swindle RW, Mallinckrodt CH, Rosenbaum JF, et al. Efficacy of duloxetine treatment: analysis of pooled data from six placebo- and SSRI-controlled clinical trials [abstract no. NR722 plus poster]. 157th Annual Meeting of the American Psychiatric Association; 2004 May 1-5; New York (NY)
    • (2004) 157th Annual Meeting of the American Psychiatric Association
    • Swindle, R.W.1    Mallinckrodt, C.H.2    Rosenbaum, J.F.3
  • 74
    • 33747732224 scopus 로고    scopus 로고
    • Efficacy of duloxetine in patients with mild, moderate, or severe depressive symptoms
    • abstract no. NR363 plus poster, May 21-26; Atlanta GA
    • Andorn AC, Mallinckrodt C, Watkin J, et al. Efficacy of duloxetine in patients with mild, moderate, or severe depressive symptoms [abstract no. NR363 plus poster]. American Psychiatric Association 158th Annual Meeting; 2005 May 21-26; Atlanta (GA), 135
    • (2005) American Psychiatric Association 158th Annual Meeting , pp. 135
    • Andorn, A.C.1    Mallinckrodt, C.2    Watkin, J.3
  • 75
    • 33750484059 scopus 로고    scopus 로고
    • Remission in placebo-controlled trials of duloxetine with an SSRI comparator [abstract no. 127]
    • Thase ME, Lu Y, Joliat M, et al. Remission in placebo-controlled trials of duloxetine with an SSRI comparator [abstract no. 127]. Biol Psychiatry 2004; 55: 37S
    • (2004) Biol Psychiatry , vol.55
    • Thase, M.E.1    Lu, Y.2    Joliat, M.3
  • 77
    • 34247116993 scopus 로고    scopus 로고
    • An independent meta-analysis using summary data for clinical response, remission, and discontinuation for any reason from the 6 pivotal phase III randomized clinical trials of duloxetine in major depressive disorder [letter]
    • Apr;
    • Ballesteros J, Callado LF, Gutierrez M. An independent meta-analysis using summary data for clinical response, remission, and discontinuation for any reason from the 6 pivotal phase III randomized clinical trials of duloxetine in major depressive disorder [letter]. J Clin Psychopharmacol 2007 Apr; 27 (2): 219-21
    • (2007) J Clin Psychopharmacol , vol.27 , Issue.2 , pp. 219-221
    • Ballesteros, J.1    Callado, L.F.2    Gutierrez, M.3
  • 78
    • 25844529324 scopus 로고    scopus 로고
    • Duloxetine for the long-term treatment of major depressive disorder in patients aged 65 and older: An open-label study
    • Dec 7;
    • Wohlreich MM, Mallinckrodt CH, Watkin JG, et al. Duloxetine for the long-term treatment of major depressive disorder in patients aged 65 and older: an open-label study. BMC Geriatr 2004 Dec 7; 4 (11)
    • (2004) BMC Geriatr , vol.4 , Issue.11
    • Wohlreich, M.M.1    Mallinckrodt, C.H.2    Watkin, J.G.3
  • 79
    • 33846669702 scopus 로고    scopus 로고
    • A retrospective pooled analysis of duloxetine safety in 23,983 subjects
    • Jan;
    • Gahimer J, Wernicke J, Yalcin I, et al. A retrospective pooled analysis of duloxetine safety in 23,983 subjects. Curr Med Res Opin 2007 Jan; 23 (1): 175-84
    • (2007) Curr Med Res Opin , vol.23 , Issue.1 , pp. 175-184
    • Gahimer, J.1    Wernicke, J.2    Yalcin, I.3
  • 80
    • 23244441627 scopus 로고    scopus 로고
    • Safety and tolerability of duloxetine in the treatment of major depressive disorder: Analysis of pooled data from eight placebo-controlled clinical trials
    • Jul;
    • Hudson JI, Wohlreich MM, Kajdasz DK, et al. Safety and tolerability of duloxetine in the treatment of major depressive disorder: analysis of pooled data from eight placebo-controlled clinical trials. Hum Psychopharmacol 2005 Jul; 20 (5): 327-41
    • (2005) Hum Psychopharmacol , vol.20 , Issue.5 , pp. 327-341
    • Hudson, J.I.1    Wohlreich, M.M.2    Kajdasz, D.K.3
  • 81
    • 33244487883 scopus 로고    scopus 로고
    • Clinical consequences of initial duloxetine dosing strategies: Comparison of 30 and 60mg QD starting doses
    • Dec 1;
    • Dunner DL, Wohlreich MM, Mallinckrodt CH, et al. Clinical consequences of initial duloxetine dosing strategies: comparison of 30 and 60mg QD starting doses. Curr Ther Res Clin Exp 2005 Dec 1; 66 (6): 522-40
    • (2005) Curr Ther Res Clin Exp , vol.66 , Issue.6 , pp. 522-540
    • Dunner, D.L.1    Wohlreich, M.M.2    Mallinckrodt, C.H.3
  • 82
    • 33847113316 scopus 로고    scopus 로고
    • Duloxetine for the treatment of major depressive disorder: Safety and tolerability associated with dose escalation
    • Wohlreich MM, Mallinckrodt CH, Prakash A, et al. Duloxetine for the treatment of major depressive disorder: safety and tolerability associated with dose escalation. Depress Anxiety 2007; 24 (1): 41-52
    • (2007) Depress Anxiety , vol.24 , Issue.1 , pp. 41-52
    • Wohlreich, M.M.1    Mallinckrodt, C.H.2    Prakash, A.3
  • 83
    • 33746253361 scopus 로고    scopus 로고
    • Duloxetine in the treatment of major depressive disorder: Comparisons of safety and tolerability in male and female patients
    • Aug;
    • Stewart DE, Wohlreich MM, Mallinckrodt CH, et al. Duloxetine in the treatment of major depressive disorder: comparisons of safety and tolerability in male and female patients. J Affect Disord 2006 Aug; 94 (1-3): 183-9
    • (2006) J Affect Disord , vol.94 , Issue.1-3 , pp. 183-189
    • Stewart, D.E.1    Wohlreich, M.M.2    Mallinckrodt, C.H.3
  • 84
    • 28444452940 scopus 로고    scopus 로고
    • Symptoms following abrupt discontinuation of duloxetine treatment in patients with major depressive disorder
    • Dec;
    • Perahia DG, Kajdasz DK, Desaiah D, et al. Symptoms following abrupt discontinuation of duloxetine treatment in patients with major depressive disorder. J Affect Disord 2005 Dec; 89 (1): 207-12
    • (2005) J Affect Disord , vol.89 , Issue.1 , pp. 207-212
    • Perahia, D.G.1    Kajdasz, D.K.2    Desaiah, D.3
  • 85
    • 34147197359 scopus 로고    scopus 로고
    • QT effects of duloxetine at supratherapeutic doses: A placebo and positive controlled study
    • Mar;
    • Zhang L, Chappell J, Gonzales CR, et al. QT effects of duloxetine at supratherapeutic doses: a placebo and positive controlled study. J Cardiovasc Pharmacol 2007 Mar; 49 (3): 146-53
    • (2007) J Cardiovasc Pharmacol , vol.49 , Issue.3 , pp. 146-153
    • Zhang, L.1    Chappell, J.2    Gonzales, C.R.3
  • 86
    • 34248329070 scopus 로고    scopus 로고
    • An evaluation of the cardiovascular safety profile of duloxetine: Findings from 42 placebo-controlled studies
    • Wernicke J, Lledo A, Raskin J, et al. An evaluation of the cardiovascular safety profile of duloxetine: findings from 42 placebo-controlled studies. Drug Saf 2007; 30 (5): 437-55
    • (2007) Drug Saf , vol.30 , Issue.5 , pp. 437-455
    • Wernicke, J.1    Lledo, A.2    Raskin, J.3
  • 87
    • 33751120962 scopus 로고    scopus 로고
    • Duloxetine: Meta-analyses of suicidal behaviors and ideation in clinical trials for major depressive disorder
    • Dec;
    • Acharya N, Rosen AS, Polzer JP, et al. Duloxetine: meta-analyses of suicidal behaviors and ideation in clinical trials for major depressive disorder. J Clin Psychopharmacol 2006 Dec; 26 (6): 587-94
    • (2006) J Clin Psychopharmacol , vol.26 , Issue.6 , pp. 587-594
    • Acharya, N.1    Rosen, A.S.2    Polzer, J.P.3
  • 88
    • 20444434280 scopus 로고    scopus 로고
    • Is treatment-associated hypomania rare with duloxetine: Secondary analysis of controlled trials in non-bipolar depression
    • Jul;
    • Dunner DL, D'Souza DN, Kajdasz DK, et al. Is treatment-associated hypomania rare with duloxetine: secondary analysis of controlled trials in non-bipolar depression. J Affect Disord 2005 Jul; 87 (1): 115-9
    • (2005) J Affect Disord , vol.87 , Issue.1 , pp. 115-119
    • Dunner, D.L.1    D'Souza, D.N.2    Kajdasz, D.K.3
  • 89
    • 21744457235 scopus 로고    scopus 로고
    • Sexual functioning assessed in 4 double-blind placebo- and paroxetine-controlled trials of duloxetine for major depressive disorder
    • Jun;
    • Delgado PL, Brannan SK, Mallinckrodt CH, et al. Sexual functioning assessed in 4 double-blind placebo- and paroxetine-controlled trials of duloxetine for major depressive disorder. J Clin Psychiatry 2005 Jun; 66 (6): 686-92
    • (2005) J Clin Psychiatry , vol.66 , Issue.6 , pp. 686-692
    • Delgado, P.L.1    Brannan, S.K.2    Mallinckrodt, C.H.3
  • 90
    • 33748529591 scopus 로고    scopus 로고
    • The safety and tolerability of duloxetine compared with paroxetine and placebo: A pooled analysis of 4 clinical trials
    • Nelson JC, Lu Pritchett Y, Martynov O, et al. The safety and tolerability of duloxetine compared with paroxetine and placebo: a pooled analysis of 4 clinical trials. Prim Care Companion J Clin Psychiatry 2006; 8 (4): 212-9
    • (2006) Prim Care Companion J Clin Psychiatry , vol.8 , Issue.4 , pp. 212-219
    • Nelson, J.C.1    Lu Pritchett, Y.2    Martynov, O.3
  • 91
    • 9744219679 scopus 로고    scopus 로고
    • Incidence and duration of antidepressant-induced nausea: Duloxetine compared with paroxetine and fluoxetine
    • Sep;
    • Greist J, McNamara RK, Mallinckrodt CH, et al. Incidence and duration of antidepressant-induced nausea: duloxetine compared with paroxetine and fluoxetine. Clin Ther 2004 Sep; 26 (9): 1446-55
    • (2004) Clin Ther , vol.26 , Issue.9 , pp. 1446-1455
    • Greist, J.1    McNamara, R.K.2    Mallinckrodt, C.H.3
  • 92
    • 34347235787 scopus 로고    scopus 로고
    • Sexual functioning in long-term treatment of MDD: Duloxetine, escitalopram, and placebo
    • abstract no. NR199 plus poster, May 20-25; Toronto ON
    • Clayton A, Mallinckrodt CH, Wohlreich MM, et al. Sexual functioning in long-term treatment of MDD: duloxetine, escitalopram, and placebo [abstract no. NR199 plus poster]. 159th Annual Meeting of the American Psychiatric Association; 2006 May 20-25; Toronto (ON), 83
    • (2006) 159th Annual Meeting of the American Psychiatric Association , pp. 83
    • Clayton, A.1    Mallinckrodt, C.H.2    Wohlreich, M.M.3
  • 93
    • 33846215883 scopus 로고    scopus 로고
    • Duloxetine and hyponatremia: A report of 5 cases [letter]
    • Feb;
    • Kruger S, Lindstaedt M. Duloxetine and hyponatremia: a report of 5 cases [letter]. J Clin Psychopharmacol 2007 Feb; 27 (1): 101-4
    • (2007) J Clin Psychopharmacol , vol.27 , Issue.1 , pp. 101-104
    • Kruger, S.1    Lindstaedt, M.2
  • 94
    • 33751089817 scopus 로고    scopus 로고
    • A case of hyponatremia induced by duloxetine [letter]
    • Dec;
    • Safdieh JE, Rudominer R. A case of hyponatremia induced by duloxetine [letter]. J Clin Psychopharmacol 2006 Dec; 26 (6): 675-6
    • (2006) J Clin Psychopharmacol , vol.26 , Issue.6 , pp. 675-676
    • Safdieh, J.E.1    Rudominer, R.2
  • 95
    • 0026769806 scopus 로고
    • Epidemiology of depression in primary care
    • Jul;
    • Katon W, Schulberg H. Epidemiology of depression in primary care. Gen Hosp Psychiatry 1992 Jul; 14 (4): 237-47
    • (1992) Gen Hosp Psychiatry , vol.14 , Issue.4 , pp. 237-247
    • Katon, W.1    Schulberg, H.2
  • 96
    • 0037831023 scopus 로고    scopus 로고
    • The epidemiology of major depressive disorder: Results from National Comorbidity Survey Replication (NCS-R)
    • Jun 18;
    • Kessler RC, Berglund P, Demler O, et al. The epidemiology of major depressive disorder: results from National Comorbidity Survey Replication (NCS-R). JAMA 2003 Jun 18; 289 (23): 3095-105
    • (2003) JAMA , vol.289 , Issue.23 , pp. 3095-3105
    • Kessler, R.C.1    Berglund, P.2    Demler, O.3
  • 97
    • 0034934419 scopus 로고    scopus 로고
    • The burden of disease for treatment-resistant depression
    • Greden JF. The burden of disease for treatment-resistant depression. J Clin Psychiatry 2001; 62 Suppl. 16: 26-31
    • (2001) J Clin Psychiatry , vol.62 , Issue.SUPPL. 16 , pp. 26-31
    • Greden, J.F.1
  • 98
    • 0031001720 scopus 로고    scopus 로고
    • Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study
    • May 24;
    • Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 1997 May 24; 349 (9064): 1498-504
    • (1997) Lancet , vol.349 , Issue.9064 , pp. 1498-1504
    • Murray, C.J.1    Lopez, A.D.2
  • 99
    • 2442569082 scopus 로고    scopus 로고
    • Global burden of depressive disorders in the year 2000
    • Ustun TB, Ayuso-Mateos JL, Chatterji S, et al. Global burden of depressive disorders in the year 2000. Br J Psychiatry 2004; 184: 386-92
    • (2004) Br J Psychiatry , vol.184 , pp. 386-392
    • Ustun, T.B.1    Ayuso-Mateos, J.L.2    Chatterji, S.3
  • 100
    • 1242338645 scopus 로고    scopus 로고
    • The economic burden of depression in the United States: How did it change between 1990 and 2000?
    • Dec;
    • Greenberg PE, Kessler RC, Birnbaum HG, et al. The economic burden of depression in the United States: how did it change between 1990 and 2000? J Clin Psychiatry 2003 Dec; 64 (12): 1465-75
    • (2003) J Clin Psychiatry , vol.64 , Issue.12 , pp. 1465-1475
    • Greenberg, P.E.1    Kessler, R.C.2    Birnbaum, H.G.3
  • 101
    • 34347204055 scopus 로고    scopus 로고
    • Gelenberg A, Merriam A, Karasu TB, et al. Practice guideline for the treatment of patients with major depressive disorder (revisions). American Psychiatric Association 2000; 157 (Suppl. 4): 1-45
    • Gelenberg A, Merriam A, Karasu TB, et al. Practice guideline for the treatment of patients with major depressive disorder (revisions). American Psychiatric Association 2000; 157 (Suppl. 4): 1-45
  • 103
    • 0034635825 scopus 로고    scopus 로고
    • NaSSAs, and NaRIs: New agents for the treatment of depression
    • Kent JM. SNaRIs, NaSSAs, and NaRIs: new agents for the treatment of depression. Lancet 2000; 355: 911-8
    • (2000) Lancet , vol.355 , pp. 911-918
    • Kent, J.S.1
  • 104
    • 24944449979 scopus 로고    scopus 로고
    • Efficacy and safety of second-generation antidepressants in the treatment of major depressive disorder
    • Sep 20;
    • Hansen RA, Gartlehner G, Lohr KN, et al. Efficacy and safety of second-generation antidepressants in the treatment of major depressive disorder. Ann Intern Med 2005 Sep 20; 143 (6): 415-26
    • (2005) Ann Intern Med , vol.143 , Issue.6 , pp. 415-426
    • Hansen, R.A.1    Gartlehner, G.2    Lohr, K.N.3
  • 105
    • 0038137619 scopus 로고    scopus 로고
    • Efficacy and tolerability of selective serotonin reuptake inhibitors compared with tricyclic antidepressants in depression treated in primary care: Systematic review and meta-analysis
    • May 10;
    • MacGillivray S, Arroll B, Hatcher S, et al. Efficacy and tolerability of selective serotonin reuptake inhibitors compared with tricyclic antidepressants in depression treated in primary care: systematic review and meta-analysis. BMJ 2003 May 10; 326 (7397): 1014
    • (2003) BMJ , vol.326 , Issue.7397 , pp. 1014
    • MacGillivray, S.1    Arroll, B.2    Hatcher, S.3
  • 106
    • 28344442596 scopus 로고    scopus 로고
    • Duloxetine: A balanced and selective norepinephrine- and serotonin-reuptake inhibitor
    • Dec 1;
    • Westanmo AD, Gayken J, Haight R. Duloxetine: a balanced and selective norepinephrine- and serotonin-reuptake inhibitor. Am J Health Syst Pharm 2005 Dec 1; 62 (23): 2481-90
    • (2005) Am J Health Syst Pharm , vol.62 , Issue.23 , pp. 2481-2490
    • Westanmo, A.D.1    Gayken, J.2    Haight, R.3
  • 107
    • 0037709235 scopus 로고    scopus 로고
    • Duloxetine: An antidepressant that inhibits both norepinephrine and serotonin uptake
    • Kirwin JL, Goren JL. Duloxetine: an antidepressant that inhibits both norepinephrine and serotonin uptake. Formulary 2003; 38: 29-37
    • (2003) Formulary , vol.38 , pp. 29-37
    • Kirwin, J.L.1    Goren, J.L.2
  • 108
    • 0029192252 scopus 로고
    • The role of the primary care physician in patients' adherence to antidepressant therapy
    • Jan;
    • Lin EH, Von Korff M, Katon W, et al. The role of the primary care physician in patients' adherence to antidepressant therapy. Med Care 1995 Jan; 33 (1): 67-74
    • (1995) Med Care , vol.33 , Issue.1 , pp. 67-74
    • Lin, E.H.1    Von Korff, M.2    Katon, W.3
  • 109
    • 26944450103 scopus 로고    scopus 로고
    • Study designs and outcomes in antidepressant clinical trials
    • Khan A, Schwartz K. Study designs and outcomes in antidepressant clinical trials. Essent Psychopharmacol 2005; 6 (4): 221-6
    • (2005) Essent Psychopharmacol , vol.6 , Issue.4 , pp. 221-226
    • Khan, A.1    Schwartz, K.2
  • 110
    • 23844557846 scopus 로고    scopus 로고
    • Time course of depression-symptom improvement during treatment with duloxetine
    • Hirschfeld RM, Mallinckrodt C, Lee TC, et al. Time course of depression-symptom improvement during treatment with duloxetine. Depress Anxiety 2005; 21 (4): 170-7
    • (2005) Depress Anxiety , vol.21 , Issue.4 , pp. 170-177
    • Hirschfeld, R.M.1    Mallinckrodt, C.2    Lee, T.C.3
  • 111
    • 0036293907 scopus 로고    scopus 로고
    • Optimizing antidepressant treatment: Efficacy and tolerability
    • Deakin B, Dursun S. Optimizing antidepressant treatment: efficacy and tolerability. Int Clin Psychopharmacol 2002; 17 Suppl. 1: S13-24
    • (2002) Int Clin Psychopharmacol , vol.17 , Issue.SUPPL. 1
    • Deakin, B.1    Dursun, S.2
  • 112
    • 33749029120 scopus 로고    scopus 로고
    • Clinical comparison of SSRIs and SNRIs in major depressive disorder: A meta-analysis [abstract no. PMH43]
    • Dec;
    • Machado M, Iskedjian M, Einarson T. Clinical comparison of SSRIs and SNRIs in major depressive disorder: a meta-analysis [abstract no. PMH43]. Value Health 2005 Dec; 8 ( 6): A209
    • (2005) Value Health , vol.8 , Issue.6
    • Machado, M.1    Iskedjian, M.2    Einarson, T.3
  • 113
    • 0035111499 scopus 로고    scopus 로고
    • Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors
    • Mar;
    • Thase ME, Entsuah AR, Rudolph RL, et al. Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors. Br J Psychiatry 2001 Mar; 178: 234-41
    • (2001) Br J Psychiatry , vol.178 , pp. 234-241
    • Thase, M.E.1    Entsuah, A.R.2    Rudolph, R.L.3
  • 114
    • 0034951724 scopus 로고    scopus 로고
    • Meta-analytical studies on new antidepressants
    • Anderson IM. Meta-analytical studies on new antidepressants. Br Med Bull 2001; 57: 161-78
    • (2001) Br Med Bull , vol.57 , pp. 161-178
    • Anderson, I.M.1
  • 115
    • 21744439183 scopus 로고    scopus 로고
    • The comorbidity of major depression and anxiety disorders: Recognition and management in primary care
    • Hirschfeld RMA. The comorbidity of major depression and anxiety disorders: recognition and management in primary care. Primary Care Companion J Clin Psychiatry 2001; 3 (6): 244-54
    • (2001) Primary Care Companion J Clin Psychiatry , vol.3 , Issue.6 , pp. 244-254
    • Hirschfeld, R.M.A.1
  • 116
    • 0032782676 scopus 로고    scopus 로고
    • Anxiety with depression: A treatment need
    • Jul;
    • Rouillon F. Anxiety with depression: a treatment need. Eur Neuropsychopharmacol 1999 Jul; 9 Suppl. 3: 87-92
    • (1999) Eur Neuropsychopharmacol , vol.9 , Issue.SUPPL. 3 , pp. 87-92
    • Rouillon, F.1
  • 118
    • 0141731324 scopus 로고    scopus 로고
    • Duloxetine in treatment of anxiety symptoms associated with depression
    • Dunner DL, Goldstein DJ, Mallinckrodt CM, et al. Duloxetine in treatment of anxiety symptoms associated with depression. Depress Anxiety 2003; 18: 53-61
    • (2003) Depress Anxiety , vol.18 , pp. 53-61
    • Dunner, D.L.1    Goldstein, D.J.2    Mallinckrodt, C.M.3
  • 119
    • 33749315762 scopus 로고    scopus 로고
    • Efficacy of duloxetine in painful symptoms: An analgesic or antidepressant effect?
    • Nov;
    • Perahia DG, Pritchett YL, Desaiah D, et al. Efficacy of duloxetine in painful symptoms: an analgesic or antidepressant effect? Int Clin Psychopharmacol 2006 Nov; 21 (6): 311-7
    • (2006) Int Clin Psychopharmacol , vol.21 , Issue.6 , pp. 311-317
    • Perahia, D.G.1    Pritchett, Y.L.2    Desaiah, D.3
  • 120
    • 0037284434 scopus 로고    scopus 로고
    • New hope in the treatment of painful symptoms in depression
    • Jan;
    • Briley M. New hope in the treatment of painful symptoms in depression. Curr Opin Investig Drugs 2003 Jan; 4 (1): 42-5
    • (2003) Curr Opin Investig Drugs , vol.4 , Issue.1 , pp. 42-45
    • Briley, M.1
  • 121
    • 33750738232 scopus 로고    scopus 로고
    • Antidepressants and sexual dysfunction
    • Dec;
    • Werneke U, Northey S, Bhugra D. Antidepressants and sexual dysfunction. Acta Psychiatr Scand 2006 Dec; 114 (6): 384-97
    • (2006) Acta Psychiatr Scand , vol.114 , Issue.6 , pp. 384-397
    • Werneke, U.1    Northey, S.2    Bhugra, D.3
  • 123
    • 33749141887 scopus 로고    scopus 로고
    • The effect of antidepressants on lipid homeostasis: A cardiac safety concern?
    • Jul;
    • McIntyre RS, Soczynska JK, Konarski JZ, et al. The effect of antidepressants on lipid homeostasis: a cardiac safety concern? Expert Opin Drug Saf 2006 Jul; 5 (4): 523-37
    • (2006) Expert Opin Drug Saf , vol.5 , Issue.4 , pp. 523-537
    • McIntyre, R.S.1    Soczynska, J.K.2    Konarski, J.Z.3
  • 124
    • 23744509384 scopus 로고    scopus 로고
    • Cost effectiveness of duloxetine compared with venlafaxine-XR in the treatment of major depressive disorder
    • Aug;
    • van Baardewijk M, Vis PMJ, Einarson TR. Cost effectiveness of duloxetine compared with venlafaxine-XR in the treatment of major depressive disorder. Curr Med Res Opin 2005 Aug; 21 (8): 1271-9
    • (2005) Curr Med Res Opin , vol.21 , Issue.8 , pp. 1271-1279
    • van Baardewijk, M.1    Vis, P.M.J.2    Einarson, T.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.