Duloxetine increases serotonin and norepinephrine availability in healthy subjects: A double-blind, controlled study

Neuropsychopharmacology

Volumn 28, Issue 9, 2003, Pages 1685-1693

  Chalon, Stephan A ^a   Granier, Luc André ^a   Vandenhende, François R ^a   Bieck, Peter R ^b   Bymaster, Frank P ^b   Joliat, Melissa J ^b   Hirth, Christine ^c   Potter, William Z ^b  

^a Eli Lilly Benelux   (Belgium)

^b ELI LILLY AND COMPANY   (United States)

^c UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Antidepressive agents; Neurotransmitter uptake inhibitors; Norepinephrine; Serotonin

Indexed keywords

DESIPRAMINE; DULOXETINE; NORADRENALIN; NORADRENALIN UPTAKE INHIBITOR; PLACEBO; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; 3-METHOXY-4-HYDROXYMANDELIC ACID; 4 HYDROXY 3 METHOXYPHENYLETHYLENE GLYCOL; ADRENERGIC RECEPTOR STIMULATING AGENT; ANTIDEPRESSANT AGENT; MANDELIC ACID DERIVATIVE; NORMETADRENALIN; THIOPHENE DERIVATIVE; TYRAMINE; VANILMANDELIC ACID;

ARTICLE; CARDIOVASCULAR EFFECT; CLINICAL TRIAL; CONCENTRATION (PARAMETERS); CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; HUMAN; MALE; METABOLITE; NORADRENALIN BLOOD LEVEL; NORADRENALIN URINE LEVEL; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEROTONIN BLOOD LEVEL; SEROTONIN RELEASE; STATISTICAL SIGNIFICANCE; STEADY STATE; SYMPATHETIC TONE; SYSTOLIC BLOOD PRESSURE; TURNOVER TIME; URINARY EXCRETION; ADULT; BLOOD; BLOOD PRESSURE; COMPARATIVE STUDY; DOSE RESPONSE; DRUG ADMINISTRATION; DRUG EFFECT; HEART RATE; TIME; URINE;

ADULT; ANTIDEPRESSIVE AGENTS; BLOOD PRESSURE; CROSS-OVER STUDIES; DESIPRAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; HEART RATE; HUMANS; MALE; MANDELIC ACIDS; METHOXYHYDROXYPHENYLGLYCOL; NOREPINEPHRINE; NORMETANEPHRINE; SEROTONIN; SYMPATHOMIMETICS; THIOPHENES; TIME FACTORS; TYRAMINE;

EID: 0141781033     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300209     Document Type: Article

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