Insights from crystallographic studies into the structural and pairing properties of nucleic acid analogs and chemically modified DNA and RNA oligonucleotides

Annual Review of Biophysics and Biomolecular Structure

Volumn 36, Issue , 2007, Pages 281-305

  Egli, Martin ^a   Pallan, Pradeep S ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

Antisense; Hydration; Nuclease resistance; Nucleic acid etiology; RNA affinity; RNA interference

Indexed keywords

2' DEOXY 2' FLUOROARABINONUCLEIC ACID; ARABINONUCLEIC ACID; DIMER; DNA; ETHER DERIVATIVE; NUCLEIC ACID; NUCLEIC ACID BASE; OLIGONUCLEOTIDE; PENTOSE; RIBOSE; RNA; STILBENE; TETROSE; THYMINE; TOLUENE DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; BASE PAIRING; CHEMICAL MODIFICATION; CONFORMATIONAL TRANSITION; CONJUGATION; CRYSTALLOGRAPHY; DNA STRUCTURE; HYDRATION; MACROMOLECULE; NUCLEIC ACID ANALYSIS; PRIORITY JOURNAL; REVIEW; RNA INTERFERENCE; RNA STRUCTURE;

BIOCHEMISTRY; BIOPHYSICS; CARBOHYDRATES; CATIONS; CRYSTALLOGRAPHY, X-RAY; DNA; MACROMOLECULAR SUBSTANCES; MODELS, CHEMICAL; MOLECULAR CONFORMATION; NUCLEIC ACIDS; OLIGONUCLEOTIDES; OLIGONUCLEOTIDES, ANTISENSE; PEPTIDE NUCLEIC ACIDS; RNA; RNA INTERFERENCE;

EID: 34347230423     PISSN: 10568700     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.biophys.36.040306.132556     Document Type: Review

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