Crystal structures of DNA:DNA and DNA:RNA duplexes containing 5-(N-aminohexyl)carbamoyl-modified uracils reveal the basis for properties as antigene and antisense molecules

Nucleic Acids Research

Volumn 35, Issue 6, 2007, Pages 1969-1977

  Magat Juan, Ella Czarina ^c   Kondo, Jiro ^c,d   Kurihara, Takeshi ^c   Ito, Takanori ^a   Ueno, Yoshihito ^b   Matsuda, Akira ^a   Takénaka, Akio ^c  

^a HOKKAIDO UNIVERSITY   (Japan)

^b GIFU UNIVERSITY   (Japan)

^c TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^d INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; ANTISENSE OLIGONUCLEOTIDE; DNA; HYDROGEN; NUCLEASE; OXYGEN; PHOSPHATE; RIBONUCLEASE H; RNA; URACIL; 5 (N AMINOHEXYL)CARBAMOYL 2' DEOXYURIDINE; 5 (N AMINOHEXYL)CARBAMOYL 2' O METHYLURIDINE; 5-(N-AMINOHEXYL)CARBAMOYL-2'-DEOXYURIDINE; 5-(N-AMINOHEXYL)CARBAMOYL-2'-O-METHYLURIDINE; DEOXYURIDINE; DNA A; DRUG DERIVATIVE; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG; URIDINE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA BINDING; DNA CONFORMATION; DNA MODIFICATION; DNA STRUCTURE; ENZYME ACTIVITY; HYDRATION; HYDROGEN BOND; PRIORITY JOURNAL; RNA BINDING; RNA STRUCTURE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; X RAY CRYSTALLOGRAPHY;

CARBOHYDRATE CONFORMATION; CRYSTALLOGRAPHY, X-RAY; DEOXYURIDINE; DNA; DNA, A-FORM; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; OLIGONUCLEOTIDES, ANTISENSE; RNA; URIDINE;

EID: 34247895758     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkl821     Document Type: Article

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