The C-terminal loop of the homing endonuclease I-CreI is essential for site recognition, DNA binding and cleavage

Nucleic Acids Research

Volumn 35, Issue 10, 2007, Pages 3262-3271

  Prieto, Jesús ^a   Redondo, Pilar ^a   Padró, Daniel ^a   Arnould, Sylvain ^b   Epinat, Jean Charles ^b   Pâques, Frédéric ^b   Blanco, Francisco J ^a   Montoya, Guillermo ^a  

^a Centro Nacional de Investigations Oncológicas   (Spain)

^b 8 rue de la Croix Jarry   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; HOMING ENDONUCLEASE; LYSINE; MUTANT PROTEIN; SERINE; THREONINE; UNCLASSIFIED DRUG; DNA; ENDODEOXYRIBONUCLEASE CREI; RESTRICTION ENDONUCLEASE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; DNA CLEAVAGE; DNA PROTEIN COMPLEX; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR RECOGNITION; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DNA INTERACTION; SITE DIRECTED MUTAGENESIS; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DIMERIZATION; GENETICS; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION;

BINDING SITES; DIMERIZATION; DNA; DNA RESTRICTION ENZYMES; LYSINE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN CONFORMATION; SERINE; SUBSTRATE SPECIFICITY; THREONINE;

EID: 34250828453     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkm183     Document Type: Article

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