-
1
-
-
14944383798
-
The evolving role of natural products in drug discovery
-
Koehn FE, Carter GT. The evolving role of natural products in drug discovery. Nat Rev Drug Discov 2005; 4: 206-20.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 206-220
-
-
Koehn, F.E.1
Carter, G.T.2
-
5
-
-
0003973514
-
The pharmacological basis of therapeutics
-
10th edition, London: McGraw-Hill;
-
Hardman JG, Limbird LE. The pharmacological basis of therapeutics, 10th edition. Goodman and Gilman's London: McGraw-Hill; 2002.
-
(2002)
Goodman and Gilman's
-
-
Hardman, J.G.1
Limbird, L.E.2
-
8
-
-
0038004785
-
Lovastatin and beyond: The history of the HMG-CoA reductase inhibitors
-
Tobert JA. Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors. Nat Rev Drug Discov 2003; 2: 517-26.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 517-526
-
-
Tobert, J.A.1
-
9
-
-
31644442734
-
The use of ciclosporin in psoriasis
-
Berth-Jones J. The use of ciclosporin in psoriasis. J Dermatol Treat 2005; 16: 258-77.
-
(2005)
J Dermatol Treat
, vol.16
, pp. 258-277
-
-
Berth-Jones, J.1
-
10
-
-
33646839918
-
Antifungal drug resistance: Limited data, dramatic impact?
-
Rogers TR. Antifungal drug resistance: limited data, dramatic impact? Int J Antimicrob Agents 2006; 27S: S7-11.
-
(2006)
Int J Antimicrob Agents
, vol.27 S
-
-
Rogers, T.R.1
-
13
-
-
0016338169
-
Metabolites of microorganisms, 143: Echino-candin B, a novel polypeptide-antibiotic from Aspergillus nidulans var. echinulatus-isolation and structural components
-
Nyfelder R, Keller SW. Metabolites of microorganisms, 143: echino-candin B, a novel polypeptide-antibiotic from Aspergillus nidulans var. echinulatus-isolation and structural components. Helv Chim Acta 1974; 57: 2459-77.
-
(1974)
Helv Chim Acta
, vol.57
, pp. 2459-2477
-
-
Nyfelder, R.1
Keller, S.W.2
-
14
-
-
0037339171
-
Caspofungin: The first representative of a new antifungal class
-
Letscher-Bru V, Herbrecht R. Caspofungin: the first representative of a new antifungal class. J Antimicrob Chemother 2003; 51: 513-21.
-
(2003)
J Antimicrob Chemother
, vol.51
, pp. 513-521
-
-
Letscher-Bru, V.1
Herbrecht, R.2
-
15
-
-
4444222950
-
Anidulafungin: Review of a new echinocandin antifungal agent
-
Raasch RH. Anidulafungin: review of a new echinocandin antifungal agent. Expert Rev Anti Infect Ther 2004; 2: 499-508.
-
(2004)
Expert Rev Anti Infect Ther
, vol.2
, pp. 499-508
-
-
Raasch, R.H.1
-
16
-
-
33745700391
-
Anidulafungin: A novel echinocandin
-
Vasquez JA, Sobel JD. Anidulafungin: a novel echinocandin. Clin Infect Dis 2006; 43: 215-22.
-
(2006)
Clin Infect Dis
, vol.43
, pp. 215-222
-
-
Vasquez, J.A.1
Sobel, J.D.2
-
18
-
-
20144387002
-
A randomized, double blind, comparative trial of micafungin (FK463) vs. fluconazole for the treatment of oesophagial candidasis
-
de Wet NT, Bester AJ, Viljoen JJ, Filho F, Suleiman JM, Ticona E et al. A randomized, double blind, comparative trial of micafungin (FK463) vs. fluconazole for the treatment of oesophagial candidasis. Aliment Pharmacol Ther 2005; 21: 899-907.
-
(2005)
Aliment Pharmacol Ther
, vol.21
, pp. 899-907
-
-
de Wet, N.T.1
Bester, A.J.2
Viljoen, J.J.3
Filho, F.4
Suleiman, J.M.5
Ticona, E.6
-
19
-
-
4544382225
-
A randomized, double-blind trial of anidulafungin versus fluconazole for the treatment of esophageal candidasis
-
Krause DS, Simjee AE, van Rensburg C, Viljoen J, Walsh TJ, Goldstein BP et al. A randomized, double-blind trial of anidulafungin versus fluconazole for the treatment of esophageal candidasis. Clin Infect Dis 2004; 39: 770-5.
-
(2004)
Clin Infect Dis
, vol.39
, pp. 770-775
-
-
Krause, D.S.1
Simjee, A.E.2
van Rensburg, C.3
Viljoen, J.4
Walsh, T.J.5
Goldstein, B.P.6
-
20
-
-
0036148508
-
Randomized, double blind, multicenter study of caspofungin versus amphotericin B in treatment of oropharyngeal and esophageal candidasis
-
Arathoon EG, Gotuzzo E, Noriega LM, Berman RS, DiNubile MJ, Sable CA. Randomized, double blind, multicenter study of caspofungin versus amphotericin B in treatment of oropharyngeal and esophageal candidasis. Antimicrob Agents Chemother 2002; 46: 451-7.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 451-457
-
-
Arathoon, E.G.1
Gotuzzo, E.2
Noriega, L.M.3
Berman, R.S.4
DiNubile, M.J.5
Sable, C.A.6
-
21
-
-
0141863188
-
Echinocandin antifungal drugs
-
Denning DW. Echinocandin antifungal drugs. Lancet 2003; 362: 1142-51.
-
(2003)
Lancet
, vol.362
, pp. 1142-1151
-
-
Denning, D.W.1
-
23
-
-
33646558628
-
Emerging echinocandins for treatment of invasive fungal infections
-
Turner MS, Drew RH, Perfect JR. Emerging echinocandins for treatment of invasive fungal infections. Expert Opin Emerg Drugs 2006; 11: 231-50.
-
(2006)
Expert Opin Emerg Drugs
, vol.11
, pp. 231-250
-
-
Turner, M.S.1
Drew, R.H.2
Perfect, J.R.3
-
24
-
-
0035239765
-
In vitro activity of a new echino-candin, LY303366, and comparison with fluconazole, flucytosine and amphotericin B against Candida species
-
Moore CB, Oakley KL, Denning DW. In vitro activity of a new echino-candin, LY303366, and comparison with fluconazole, flucytosine and amphotericin B against Candida species. Clin Microbiol Infect 2001; 7: 11-6.
-
(2001)
Clin Microbiol Infect
, vol.7
, pp. 11-16
-
-
Moore, C.B.1
Oakley, K.L.2
Denning, D.W.3
-
25
-
-
0028283764
-
Morphological effects of lipopeptides against Aspergillus fumigatus correlate with activities against (1,3)-β-D-glucan synthase
-
Kurtz MB, Heath IB, Marrinan J, Dreikorn S, Onishi J, Douglas C. Morphological effects of lipopeptides against Aspergillus fumigatus correlate with activities against (1,3)-β-D-glucan synthase. Antimicrob Agents Chemother 1994; 38: 1480-9.
-
(1994)
Antimicrob Agents Chemother
, vol.38
, pp. 1480-1489
-
-
Kurtz, M.B.1
Heath, I.B.2
Marrinan, J.3
Dreikorn, S.4
Onishi, J.5
Douglas, C.6
-
26
-
-
0030055323
-
Characterization of echinocandin-resistant mutants of Candida albicans: Genetic, biochemical, and virulence studies
-
Kurtz MB, Abruzzo G, Flattery A, Bartizal K, Marrinan J, Li W et al. Characterization of echinocandin-resistant mutants of Candida albicans: genetic, biochemical, and virulence studies. Infect Immun 1996; 64: 3244-51.
-
(1996)
Infect Immun
, vol.64
, pp. 3244-3251
-
-
Kurtz, M.B.1
Abruzzo, G.2
Flattery, A.3
Bartizal, K.4
Marrinan, J.5
Li, W.6
-
27
-
-
0035147012
-
Sordarin antifungal agents
-
Odds FC. Sordarin antifungal agents. Expert Opin Ther Patents 2001; 11: 283-94.
-
(2001)
Expert Opin Ther Patents
, vol.11
, pp. 283-294
-
-
Odds, F.C.1
-
28
-
-
34250334108
-
Sordarins: Inhibitors of fungal elongation factor-2
-
An Z, editor, New York: Marcel Dekker;
-
Dominguez JM, Martin JJ. Sordarins: inhibitors of fungal elongation factor-2. In: An Z, editor. Handbook of industrial mycology New York: Marcel Dekker; 2004: 335-53.
-
(2004)
Handbook of industrial mycology
, pp. 335-353
-
-
Dominguez, J.M.1
Martin, J.J.2
-
29
-
-
0014996098
-
Isolierung und Abbau von Sordarin
-
Hauser D, Sigg HP. Isolierung und Abbau von Sordarin. Helv Chim Acta 1971; 54: 1178-90.
-
(1971)
Helv Chim Acta
, vol.54
, pp. 1178-1190
-
-
Hauser, D.1
Sigg, H.P.2
-
30
-
-
0039058563
-
Sordarins: A new class of antifungals with selective inhibition of the protein synthesis elongation cycle in yeasts
-
Dominguez JM, Kelly VA, Kinsman OS, Marriott MS, Gómez de las Heras F, Martin JJ. Sordarins: a new class of antifungals with selective inhibition of the protein synthesis elongation cycle in yeasts. Antimicrob Agents Chemother 1998; 42: 2274-8.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 2274-2278
-
-
Dominguez, J.M.1
Kelly, V.A.2
Kinsman, O.S.3
Marriott, M.S.4
Gómez de las Heras, F.5
Martin, J.J.6
-
31
-
-
0034775138
-
Antifungal activities and cytotoxicity studies of six new azasordarins
-
Herreros E, Almela MJ, Lozano S, Gómez de las Heras F, Gargallo-Viola D. Antifungal activities and cytotoxicity studies of six new azasordarins. Antimicrob Agents Chemother 2001; 45: 3132-9.
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 3132-3139
-
-
Herreros, E.1
Almela, M.J.2
Lozano, S.3
Gómez de las Heras, F.4
Gargallo-Viola, D.5
-
32
-
-
28844492626
-
The discovery of moriniafungin, a novel sordarin derivative produced by Morinia pestalozzioides
-
Basilio A, Justice M, Harris G, Bills G, Collado J, de la Cruz M et al. The discovery of moriniafungin, a novel sordarin derivative produced by Morinia pestalozzioides. Bioorg Med Chem 2006; 14: 560-6.
-
(2006)
Bioorg Med Chem
, vol.14
, pp. 560-566
-
-
Basilio, A.1
Justice, M.2
Harris, G.3
Bills, G.4
Collado, J.5
de la Cruz, M.6
-
33
-
-
0040837015
-
Identification of Elongation Factor 2 as the essential protein targeted by Sordarins in Candida albicans
-
Dominguez JM, Martin JJ. Identification of Elongation Factor 2 as the essential protein targeted by Sordarins in Candida albicans. Antimicrob Agents Chemother 1998; 42: 2279-83.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 2279-2283
-
-
Dominguez, J.M.1
Martin, J.J.2
-
34
-
-
0035991975
-
Therapeutic efficacies of GW471552 and GW471558, two new azasordarin derivatives, against pneumocystosis in two immunosuppressed-rat models
-
Jimenez E, Martinez A, Aliouat EM, Caballero J, Dei-Cas E, Gargallo-Viola D. Therapeutic efficacies of GW471552 and GW471558, two new azasordarin derivatives, against pneumocystosis in two immunosuppressed-rat models. Antimicrob Agents Chemother 2002; 46: 2648-50.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 2648-2650
-
-
Jimenez, E.1
Martinez, A.2
Aliouat, E.M.3
Caballero, J.4
Dei-Cas, E.5
Gargallo-Viola, D.6
-
35
-
-
11244280136
-
Antifungal activities of R-135853, a sordarin derivative, in experimental candidiasis in mice
-
Kamai Y, Kakuta M, Shibayama T, Fukuoka T, Kuwahara S. Antifungal activities of R-135853, a sordarin derivative, in experimental candidiasis in mice. Antimicrob Agents Chemother 2005; 49: 52-6.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 52-56
-
-
Kamai, Y.1
Kakuta, M.2
Shibayama, T.3
Fukuoka, T.4
Kuwahara, S.5
-
36
-
-
0034501311
-
Pleuromutilin Antibiotics
-
Hunt E. Pleuromutilin Antibiotics Drugs. Future 2000; 25: 1163-8.
-
(2000)
Drugs. Future
, vol.25
, pp. 1163-1168
-
-
Hunt, E.1
-
37
-
-
9644281855
-
Inhibition of peptide bond formation by pleuromutilins: The structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin
-
Schlünzen F, Pyetan E, Fucini P, Yonath A, Harms JM. Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin. Mol Microbiol 2004; 54: 1287-94.
-
(2004)
Mol Microbiol
, vol.54
, pp. 1287-1294
-
-
Schlünzen, F.1
Pyetan, E.2
Fucini, P.3
Yonath, A.4
Harms, J.M.5
-
38
-
-
33645767206
-
Interaction of pleuromutilin derivatives with the ribosomal peptidyl transferase center
-
Long KS, Hansen LH, Jakobsen L, Vester B. Interaction of pleuromutilin derivatives with the ribosomal peptidyl transferase center. Antimicrob Agents Chemother 2006; 50: 1458-62.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 1458-1462
-
-
Long, K.S.1
Hansen, L.H.2
Jakobsen, L.3
Vester, B.4
-
39
-
-
33745587824
-
Activity of retapamulin (SB-275833), a novel pleuromutilin, against selected resistant gram-positive cocci
-
Jones RN, Fritsche TR, Sader HS, Ross JE. Activity of retapamulin (SB-275833), a novel pleuromutilin, against selected resistant gram-positive cocci. Antimicrob Agents Chemother 2006; 50: 2583-6.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 2583-2586
-
-
Jones, R.N.1
Fritsche, T.R.2
Sader, H.S.3
Ross, J.E.4
-
40
-
-
33646453468
-
Activity of retapamulin against Streptococcus pyogenes and Staphylo coccus aureus evaluated by agar dilution, microdilution, E-test, and disk diffusion methodologies
-
Pankuch GA, Lin G, Hoellman DB, Good CE, Jacobs MR, Appelbaum PC. Activity of retapamulin against Streptococcus pyogenes and Staphylo coccus aureus evaluated by agar dilution, microdilution, E-test, and disk diffusion methodologies. Antimicrob Agents Chemother 2006; 50: 1727-30.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 1727-1730
-
-
Pankuch, G.A.1
Lin, G.2
Hoellman, D.B.3
Good, C.E.4
Jacobs, M.R.5
Appelbaum, P.C.6
-
41
-
-
34547532963
-
Retapamulin ointment twice daily for 5 days vs oral cephalexin twice daily for 10 days for empiric treatment of secondarily infected traumatic lesions of the skin
-
Free A, Roth E, Dalessandro M, Hiram J, Scangarella N, Shawar R et al. Retapamulin ointment twice daily for 5 days vs oral cephalexin twice daily for 10 days for empiric treatment of secondarily infected traumatic lesions of the skin. Skinmed 2006; 5: 224-32.
-
(2006)
Skinmed
, vol.5
, pp. 224-232
-
-
Free, A.1
Roth, E.2
Dalessandro, M.3
Hiram, J.4
Scangarella, N.5
Shawar, R.6
-
42
-
-
33750801913
-
(On behalf of the SB275833/032 study team.) Topical retapamulin ointment (1%, wt/wt) twice daily for 5 days versus oral cephalexin twice daily for 10 days in the treatment of secondarily infected dermatitis: Results of a randomized controlled trial
-
Parish LC, Jorizzo JL, Breton JJ, Hirman JW, Scangarella NE, Shawar RM et al. (On behalf of the SB275833/032 study team.) Topical retapamulin ointment (1%, wt/wt) twice daily for 5 days versus oral cephalexin twice daily for 10 days in the treatment of secondarily infected dermatitis: Results of a randomized controlled trial. J Am Acad Dermatol 2006; 55: 1006-16.
-
(2006)
J Am Acad Dermatol
, vol.55
, pp. 1006-1016
-
-
Parish, L.C.1
Jorizzo, J.L.2
Breton, J.J.3
Hirman, J.W.4
Scangarella, N.E.5
Shawar, R.M.6
-
43
-
-
0027322754
-
Clerocidin, a terpenoid antibiotic, inhibits bacterial DNA gyrase
-
Cullough JE, Muller MT, Howells AJ, Maxwell A, O'Sullivan J, Summerill RS et al. Clerocidin, a terpenoid antibiotic, inhibits bacterial DNA gyrase. J Antibiot 1993; 46: 526-30.
-
(1993)
J Antibiot
, vol.46
, pp. 526-530
-
-
Cullough, J.E.1
Muller, M.T.2
Howells, A.J.3
Maxwell, A.4
O'Sullivan, J.5
Summerill, R.S.6
-
44
-
-
33645833395
-
Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage
-
Richter SN, Leo E, Giaretta G, Gatto B, Fischer LM, Palumbo M. Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage. Nucleic Acids Res 2006; 34: 1982-91.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 1982-1991
-
-
Richter, S.N.1
Leo, E.2
Giaretta, G.3
Gatto, B.4
Fischer, L.M.5
Palumbo, M.6
-
45
-
-
27144504220
-
Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus
-
Mygind PH, Fischer RL, Schnorr KM, Mogens TH, Sönksen CP, Ludvigsen S et al. Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus. Nature 2005; 437: 975-80.
-
(2005)
Nature
, vol.437
, pp. 975-980
-
-
Mygind, P.H.1
Fischer, R.L.2
Schnorr, K.M.3
Mogens, T.H.4
Sönksen, C.P.5
Ludvigsen, S.6
-
46
-
-
32944471770
-
Antimicrobial peptides (AMPs): Peptide structure and mode of action
-
Park Y, Hahm KS. Antimicrobial peptides (AMPs): peptide structure and mode of action. J Biochem Mol Biol 2005; 38: 507-16.
-
(2005)
J Biochem Mol Biol
, vol.38
, pp. 507-516
-
-
Park, Y.1
Hahm, K.S.2
-
47
-
-
16844364771
-
Improving on nature's defenses: Optimization & high throughput screening of antimicrobial peptides
-
Raventós D, Taboureau O, Mygind PH, Nielsen JD, Sonksen CP, Kristensen HH. Improving on nature's defenses: optimization & high throughput screening of antimicrobial peptides. Comb Chem High Throughput Screen 2005; 8: 219-33.
-
(2005)
Comb Chem High Throughput Screen
, vol.8
, pp. 219-233
-
-
Raventós, D.1
Taboureau, O.2
Mygind, P.H.3
Nielsen, J.D.4
Sonksen, C.P.5
Kristensen, H.H.6
-
50
-
-
2542549719
-
Isolation, structure, absolute stereochemistry, and HIV-1 integrase inhibitory activity of integrasone, a novel fungal polyketide
-
Herath KB, Jayasuriya H, Bills GF, Polishook JD, Dombrowski AW, Guan Z et al. Isolation, structure, absolute stereochemistry, and HIV-1 integrase inhibitory activity of integrasone, a novel fungal polyketide. J Nat Prod 2004; 67: 872-4.
-
(2004)
J Nat Prod
, vol.67
, pp. 872-874
-
-
Herath, K.B.1
Jayasuriya, H.2
Bills, G.F.3
Polishook, J.D.4
Dombrowski, A.W.5
Guan, Z.6
-
51
-
-
18844366412
-
Discovery of natural product inhibitors of HIV-1 integrase at Merck
-
Singh SB, Pelaez F, Hazuda DJ, Lingham RB. Discovery of natural product inhibitors of HIV-1 integrase at Merck. Drugs Future 2005; 30: 277-99.
-
(2005)
Drugs Future
, vol.30
, pp. 277-299
-
-
Singh, S.B.1
Pelaez, F.2
Hazuda, D.J.3
Lingham, R.B.4
-
52
-
-
0041353616
-
Metal-dependent inhibition of HIV-1 integrase by β-diketo acids and resistance of the soluble double-mutant (F185K/C280S)
-
Marchand C, Johnson A, Karki RG, Pais GCG, Zhang X, Cowansage K et al. Metal-dependent inhibition of HIV-1 integrase by β-diketo acids and resistance of the soluble double-mutant (F185K/C280S). Mol Pharmacol 2003; 64: 600-9.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 600-609
-
-
Marchand, C.1
Johnson, A.2
Karki, R.G.3
Pais, G.C.G.4
Zhang, X.5
Cowansage, K.6
-
53
-
-
33644839220
-
Host sphingolipid biosynthesis as a target for hepatitis C virus therapy
-
Sakamoto H, Okamoto K, Aoki M, Kato H, Katsume A, Ohta A. Host sphingolipid biosynthesis as a target for hepatitis C virus therapy. Nat Chem Biol 2005; 1: 333-7.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 333-337
-
-
Sakamoto, H.1
Okamoto, K.2
Aoki, M.3
Kato, H.4
Katsume, A.5
Ohta, A.6
-
54
-
-
0032821945
-
Metabolism of antitumor hydroxymethylacylfulvene by rat liver cytosol
-
McMorris TC, Elayadi AN, Yu J, Hu Y, Kelner MJ. Metabolism of antitumor hydroxymethylacylfulvene by rat liver cytosol. Drug Metab Dispos 1999; 27: 983-5.
-
(1999)
Drug Metab Dispos
, vol.27
, pp. 983-985
-
-
McMorris, T.C.1
Elayadi, A.N.2
Yu, J.3
Hu, Y.4
Kelner, M.J.5
-
56
-
-
0035823281
-
Structure-activity studies of antitumor agent irofulvene (hydroxymethylacylfulvene) and analogues
-
McMorris TC, Yu J, Lira R, Dawe R, MacDonald JR, Waters SJ et al. Structure-activity studies of antitumor agent irofulvene (hydroxymethylacylfulvene) and analogues. J Org Chem 2001; 66: 6158-63.
-
(2001)
J Org Chem
, vol.66
, pp. 6158-6163
-
-
McMorris, T.C.1
Yu, J.2
Lira, R.3
Dawe, R.4
MacDonald, J.R.5
Waters, S.J.6
-
57
-
-
0345826109
-
Ab initio structure/reactivity investigations of illudin-based antitumor agents: A model for reaction in vivo
-
Gregerson LN, McMorris TC, Siegel JS, Baldridge KK. Ab initio structure/reactivity investigations of illudin-based antitumor agents: a model for reaction in vivo. Helv Chim Acta 2003; 86: 4133-51.
-
(2003)
Helv Chim Acta
, vol.86
, pp. 4133-4151
-
-
Gregerson, L.N.1
McMorris, T.C.2
Siegel, J.S.3
Baldridge, K.K.4
-
58
-
-
0025168447
-
Preclinical evaluation of illudins as anticancer agents: Basis for selective cytotoxity
-
Kelner MJ, McMorris TC, Taetle R. Preclinical evaluation of illudins as anticancer agents: basis for selective cytotoxity. J Natl Cancer Inst 1990; 82: 1562-5.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1562-1565
-
-
Kelner, M.J.1
McMorris, T.C.2
Taetle, R.3
-
59
-
-
33644504528
-
A phase II study of irofulvene in women with recurrent and heavily pretreated ovarian cancer
-
Seiden MV, Gordon AN, Bodurka DC, Matulonis UA, Penson RT, Reed E et al. A phase II study of irofulvene in women with recurrent and heavily pretreated ovarian cancer. Gynecol Oncol 2006; 101: 55-61.
-
(2006)
Gynecol Oncol
, vol.101
, pp. 55-61
-
-
Seiden, M.V.1
Gordon, A.N.2
Bodurka, D.C.3
Matulonis, U.A.4
Penson, R.T.5
Reed, E.6
-
60
-
-
13444303832
-
Irofulven demonstrates clinical activity against metastatic hormone-refractory prostate cancer in a phase 2 single-agent trial
-
Senzer N, Arsenau J, Richards D, Berman B, MacDonald JR, Smith S. Irofulven demonstrates clinical activity against metastatic hormone-refractory prostate cancer in a phase 2 single-agent trial. Am J Clin Oncol 2005; 28: 36-41.
-
(2005)
Am J Clin Oncol
, vol.28
, pp. 36-41
-
-
Senzer, N.1
Arsenau, J.2
Richards, D.3
Berman, B.4
MacDonald, J.R.5
Smith, S.6
-
61
-
-
33745775428
-
Phase I trial of irofulven (MG 114) in pediatric patients with solid tumors
-
Bomgaars LR, Megason GC, Pullen J, Langevin AM, Weitman SD, Hershon L et al. Phase I trial of irofulven (MG 114) in pediatric patients with solid tumors. Pediatr Blood Cancer 2006; 47: 163-8.
-
(2006)
Pediatr Blood Cancer
, vol.47
, pp. 163-168
-
-
Bomgaars, L.R.1
Megason, G.C.2
Pullen, J.3
Langevin, A.M.4
Weitman, S.D.5
Hershon, L.6
-
62
-
-
30644468474
-
Characterizations of irofulven cytotoxity in combination with cisplatin and oxaliplatin in human colon, breast, and ovarian cancer cells
-
Serova M, Calvo F, Lokiec F, Koeppel F, Poindessous V, Larsen AK et al. Characterizations of irofulven cytotoxity in combination with cisplatin and oxaliplatin in human colon, breast, and ovarian cancer cells. Cancer Chemother Pharmacol 2006; 57: 491-9.
-
(2006)
Cancer Chemother Pharmacol
, vol.57
, pp. 491-499
-
-
Serova, M.1
Calvo, F.2
Lokiec, F.3
Koeppel, F.4
Poindessous, V.5
Larsen, A.K.6
-
63
-
-
1442326153
-
Activity of irofulven against human pancreatic carcinoma cell lines in vitro and in vivo
-
Van Laar ES, Roth S, Weitman S, MacDonald JR, Waters SJ. Activity of irofulven against human pancreatic carcinoma cell lines in vitro and in vivo. Anticancer Res 2004; 24: 59-65.
-
(2004)
Anticancer Res
, vol.24
, pp. 59-65
-
-
Van Laar, E.S.1
Roth, S.2
Weitman, S.3
MacDonald, J.R.4
Waters, S.J.5
-
64
-
-
33748526850
-
A chemical and genetic approach to the mode of action of fumagillin
-
Zhang Y, Yeh JR, Mara A, Ju R, Hines JF, Cirone P et al. A chemical and genetic approach to the mode of action of fumagillin. Chem Biol 2006; 13: 1001-9.
-
(2006)
Chem Biol
, vol.13
, pp. 1001-1009
-
-
Zhang, Y.1
Yeh, J.R.2
Mara, A.3
Ju, R.4
Hines, J.F.5
Cirone, P.6
-
65
-
-
33748850356
-
-
Lu J, Chong CR, Hu X, Liu JO. Fumarranol, a rearranged fumagillin analogue that inhibits angiogenesis in vivo. J Med Chem 2006; 49: 5645-8.
-
Lu J, Chong CR, Hu X, Liu JO. Fumarranol, a rearranged fumagillin analogue that inhibits angiogenesis in vivo. J Med Chem 2006; 49: 5645-8.
-
-
-
-
66
-
-
3242727454
-
A methionine aminopeptidase-2 inhibitor, PPI-2458, for the treatment of rheumatoid arthritis
-
Bernier SG, Lazarus DD, Clark E, Doyle B, Labenski MT, Thompson CD et al. A methionine aminopeptidase-2 inhibitor, PPI-2458, for the treatment of rheumatoid arthritis. Proc Natl Acad Sci USA 2004; 101: 0768-73.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 0768-0773
-
-
Bernier, S.G.1
Lazarus, D.D.2
Clark, E.3
Doyle, B.4
Labenski, M.T.5
Thompson, C.D.6
-
67
-
-
33744486327
-
Antimicrosporidial activities of fumagillin, TNP-470, ovalicin, and ovalicin derivatives in vitro and in vivo
-
Didier PJ, Phillips JN, Kuebler DJ, Nasr M, Brindley PJ, Stovall ME et al. Antimicrosporidial activities of fumagillin, TNP-470, ovalicin, and ovalicin derivatives in vitro and in vivo. Antimicrob Agents Chemother 2006; 50: 2146-55.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 2146-2155
-
-
Didier, P.J.1
Phillips, J.N.2
Kuebler, D.J.3
Nasr, M.4
Brindley, P.J.5
Stovall, M.E.6
-
68
-
-
0032143275
-
-
Usui T, Kondoh M, Cui CB, Mayumi T, Osada H. Tryprostatin A, a specific and novel inhibitor of microtubule assembly. Biochem J 1998; 333: 543-8.
-
Usui T, Kondoh M, Cui CB, Mayumi T, Osada H. Tryprostatin A, a specific and novel inhibitor of microtubule assembly. Biochem J 1998; 333: 543-8.
-
-
-
-
69
-
-
0037061593
-
Biological activity of the tryprostatins and their diastereomers on human carcinoma cell lines
-
Zhao S, Smith KS, Deveau AM, Dieckhaus CM, Johnson MA, Macdonald TL et al. Biological activity of the tryprostatins and their diastereomers on human carcinoma cell lines. J Med Chem 2002; 45: 1559-62.
-
(2002)
J Med Chem
, vol.45
, pp. 1559-1562
-
-
Zhao, S.1
Smith, K.S.2
Deveau, A.M.3
Dieckhaus, C.M.4
Johnson, M.A.5
Macdonald, T.L.6
-
70
-
-
0033966957
-
Fumitre-morgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein
-
Rabindran SK, Ross DD, Doyle LA, Yang W, Greenberger LM. Fumitre-morgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res 2000; 60 : 7-50.
-
(2000)
Cancer Res
, vol.60
, pp. 7-50
-
-
Rabindran, S.K.1
Ross, D.D.2
Doyle, L.A.3
Yang, W.4
Greenberger, L.M.5
-
71
-
-
0017110558
-
Studies on the metabolic products of Aspergillus terreus. I. Metabolites of the strain IFO 6123
-
Yamamoto Y, Nishimura KI, Kiriyama N. Studies on the metabolic products of Aspergillus terreus. I. Metabolites of the strain IFO 6123. Chem Pharm Bull 1976; 24: 853-9.
-
(1976)
Chem Pharm Bull
, vol.24
, pp. 853-859
-
-
Yamamoto, Y.1
Nishimura, K.I.2
Kiriyama, N.3
-
72
-
-
0017171535
-
Antitumor activity of asterriquinone, a metabolic product from Aspergillus terreus
-
Yamamoto Y, Kiriyama N, Shimizu S, Koshimura S. Antitumor activity of asterriquinone, a metabolic product from Aspergillus terreus. Gann 1976; 67: 623-4.
-
(1976)
Gann
, vol.67
, pp. 623-624
-
-
Yamamoto, Y.1
Kiriyama, N.2
Shimizu, S.3
Koshimura, S.4
-
73
-
-
0031883390
-
Studies on the cytotoxicity of asterriquinone derivatives
-
Kaji A, Iwata T, Kiriyama N, Nomura M, Miyamoto KI. Studies on the cytotoxicity of asterriquinone derivatives. J Antibiot 1998; 51: 235-8.
-
(1998)
J Antibiot
, vol.51
, pp. 235-238
-
-
Kaji, A.1
Iwata, T.2
Kiriyama, N.3
Nomura, M.4
Miyamoto, K.I.5
-
74
-
-
0031005987
-
Semicochliodinol A and B: Inhibitors of HIV-1 protease and EGF-R protein tyrosine kinase related to asterriquinones produced by the fungus Chrysosporium merdarium
-
Fredenhagen A, Petersen F, Tintelot-Blomley M, Rösel J, Mett H, Hug P. Semicochliodinol A and B: inhibitors of HIV-1 protease and EGF-R protein tyrosine kinase related to asterriquinones produced by the fungus Chrysosporium merdarium. J Antibiot 1997; 50: 395-401.
-
(1997)
J Antibiot
, vol.50
, pp. 395-401
-
-
Fredenhagen, A.1
Petersen, F.2
Tintelot-Blomley, M.3
Rösel, J.4
Mett, H.5
Hug, P.6
-
75
-
-
0033532347
-
Discovery of a small molecule insulin mimetic with antidiabetic activity in mice
-
Zhang B, Salituro G, Szalkowski D, Li Z, Zhang Y, Royo I et al. Discovery of a small molecule insulin mimetic with antidiabetic activity in mice. Science 1999; 284: 974-7.
-
(1999)
Science
, vol.284
, pp. 974-977
-
-
Zhang, B.1
Salituro, G.2
Szalkowski, D.3
Li, Z.4
Zhang, Y.5
Royo, I.6
-
76
-
-
23044474009
-
Therapeutic actions of an insulin receptor activator and a novel peroxisome proliferatoraActivated receptor γ-agonist in the spontaneously hypertensive obese rat model of metabolic syndrome X
-
Velliquette RA, Friedman JE, Shao J, Zhang B, Ernsberger P. Therapeutic actions of an insulin receptor activator and a novel peroxisome proliferatoraActivated receptor γ-agonist in the spontaneously hypertensive obese rat model of metabolic syndrome X. J Pharmacol Exp Ther 2005; 314: 422-30.
-
(2005)
J Pharmacol Exp Ther
, vol.314
, pp. 422-430
-
-
Velliquette, R.A.1
Friedman, J.E.2
Shao, J.3
Zhang, B.4
Ernsberger, P.5
-
77
-
-
0031079973
-
Metabolic pathway gene clusters in filamentous fungi
-
Keller NP, Hohn TM. Metabolic pathway gene clusters in filamentous fungi. Fungal Genet Biol 1997; 21: 17-29.
-
(1997)
Fungal Genet Biol
, vol.21
, pp. 17-29
-
-
Keller, N.P.1
Hohn, T.M.2
-
78
-
-
33947694781
-
Natural products of filamentous fungi: Enzymes, genes, and their regulation
-
in press
-
Hoffmeister D, Keller NP. Natural products of filamentous fungi: enzymes, genes, and their regulation. Nat Prod Rep; 2007, in press.
-
(2007)
Nat Prod Rep
-
-
Hoffmeister, D.1
Keller, N.P.2
-
79
-
-
4143090400
-
-
Bok JW, Keller NP. LaeA, a regulator of secondary metabolism in Aspergillus spp. Euk Cell 2004; 3: 527-35.
-
Bok JW, Keller NP. LaeA, a regulator of secondary metabolism in Aspergillus spp. Euk Cell 2004; 3: 527-35.
-
-
-
-
80
-
-
0033738805
-
Role of horizontal gene transfer in the evolution of fungi
-
Rosewich UL, Kistler HC. Role of horizontal gene transfer in the evolution of fungi. Annu Rev Phytopathol 2000; 38: 325-63.
-
(2000)
Annu Rev Phytopathol
, vol.38
, pp. 325-363
-
-
Rosewich, U.L.1
Kistler, H.C.2
-
81
-
-
0033762670
-
Horizontal gene transfer and the evolution of secondary metabolite gene clusters in fungi: An hypothesis
-
Walton JD. Horizontal gene transfer and the evolution of secondary metabolite gene clusters in fungi: an hypothesis. Fungal Genet Biol 2000; 30: 167-71.
-
(2000)
Fungal Genet Biol
, vol.30
, pp. 167-171
-
-
Walton, J.D.1
-
82
-
-
33645451499
-
The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites
-
Hill AM. The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites. Nat Prod Rep 2006; 23: 256-320.
-
(2006)
Nat Prod Rep
, vol.23
, pp. 256-320
-
-
Hill, A.M.1
-
83
-
-
1642304143
-
Polyketide and nonribosomal peptide antibiotics: Modularity and versatility
-
Walsh CT. Polyketide and nonribosomal peptide antibiotics: modularity and versatility. Science 2004; 303: 1805-10.
-
(2004)
Science
, vol.303
, pp. 1805-1810
-
-
Walsh, C.T.1
-
85
-
-
33745969462
-
Advances in cloning, functional analysis and heterologous expression of fungal polyketide synthase genes
-
Schümann J, Hertweck C. Advances in cloning, functional analysis and heterologous expression of fungal polyketide synthase genes. J Biotechnol 2006; 124: 690-703.
-
(2006)
J Biotechnol
, vol.124
, pp. 690-703
-
-
Schümann, J.1
Hertweck, C.2
-
86
-
-
0031873963
-
New aspects of genes and enzymes for beta-lactam antibiotic biosynthesis
-
Martin JF. New aspects of genes and enzymes for beta-lactam antibiotic biosynthesis. Appl Microbiol Biotechnol 1998; 50: 1-15.
-
(1998)
Appl Microbiol Biotechnol
, vol.50
, pp. 1-15
-
-
Martin, J.F.1
-
87
-
-
0038236925
-
Industrial production of beta-lactam antibiotics
-
Elander RP. Industrial production of beta-lactam antibiotics. Appl Microbiol Biotechnol 2003; 61: 385-92.
-
(2003)
Appl Microbiol Biotechnol
, vol.61
, pp. 385-392
-
-
Elander, R.P.1
-
88
-
-
0026800606
-
Penicillin and cephalosporin biosynthetic genes: Structure, organization, regulation, and evolution
-
Aharonowitz Y, Cohen G, Martin JF. Penicillin and cephalosporin biosynthetic genes: structure, organization, regulation, and evolution. Annu Rev Microbiol 1992; 46: 461-95.
-
(1992)
Annu Rev Microbiol
, vol.46
, pp. 461-495
-
-
Aharonowitz, Y.1
Cohen, G.2
Martin, J.F.3
-
89
-
-
33645581640
-
Amplification and disruption of the phenylacetyl-CoA ligase gene of Penicillium chrysogenum encoding an aryl-capping enzyme that supplies phenylacetic acid to the isopenicillin N-acyltransferase
-
Lamas-Maceiras M, Vaca I, Rodriguez E, Casqueiro J, Martin JF. Amplification and disruption of the phenylacetyl-CoA ligase gene of Penicillium chrysogenum encoding an aryl-capping enzyme that supplies phenylacetic acid to the isopenicillin N-acyltransferase. Biochem J 2006; 395: 147-55.
-
(2006)
Biochem J
, vol.395
, pp. 147-155
-
-
Lamas-Maceiras, M.1
Vaca, I.2
Rodriguez, E.3
Casqueiro, J.4
Martin, J.F.5
-
90
-
-
33746806667
-
Transcriptional and bioinformatic analysis of the 56.8 kb DNA region amplified in tandem repeats containing the penicillin gene cluster in Penicillium chrysogenum
-
Fierro F, Garcia-Estrada C, Castillo NI, Rodriguez R, Velasco-Conde T, Martin JF. Transcriptional and bioinformatic analysis of the 56.8 kb DNA region amplified in tandem repeats containing the penicillin gene cluster in Penicillium chrysogenum. Fungal Genet Biol 2006; 43: 618-29.
-
(2006)
Fungal Genet Biol
, vol.43
, pp. 618-629
-
-
Fierro, F.1
Garcia-Estrada, C.2
Castillo, N.I.3
Rodriguez, R.4
Velasco-Conde, T.5
Martin, J.F.6
-
91
-
-
0033554721
-
The reaction cycle of isopenicillin-N-synthase observed by X-ray diffraction
-
Burzlaff NI, Rutledge PJ, Clifton IJ, Hensgens CM, Pickford M, Adlington RM et al. The reaction cycle of isopenicillin-N-synthase observed by X-ray diffraction. Nature 1999; 401: 721-4.
-
(1999)
Nature
, vol.401
, pp. 721-724
-
-
Burzlaff, N.I.1
Rutledge, P.J.2
Clifton, I.J.3
Hensgens, C.M.4
Pickford, M.5
Adlington, R.M.6
-
92
-
-
0032552110
-
Structure of a cephalosporin synthase
-
Valegard K, van Scheltinga AC, Lloyd MD, Hara T, Ramaswamy S, Perrakis A et al. Structure of a cephalosporin synthase. Nature 1998; 394: 805-9.
-
(1998)
Nature
, vol.394
, pp. 805-809
-
-
Valegard, K.1
van Scheltinga, A.C.2
Lloyd, M.D.3
Hara, T.4
Ramaswamy, S.5
Perrakis, A.6
-
93
-
-
25944438418
-
On the incorporation of mevalonic acid in the ergoline system of clavine alkaloids
-
Gröger D, Mothes KV, Simon H, Floss HG, Weygand F. On the incorporation of mevalonic acid in the ergoline system of clavine alkaloids. Z Naturforsch 1960; 15B: 141-3.
-
(1960)
Z Naturforsch
, vol.15 B
, pp. 141-143
-
-
Gröger, D.1
Mothes, K.V.2
Simon, H.3
Floss, H.G.4
Weygand, F.5
-
94
-
-
77956679296
-
Biochemistry of ergot alkaloids - achievements and challenges
-
Cordell GA, editor, San Diego: Academic Press;
-
Gröger D, Floss HG. Biochemistry of ergot alkaloids - achievements and challenges. In: Cordell GA, editor. The Alkaloids. San Diego: Academic Press; 1998: 171-218.
-
(1998)
The Alkaloids
, pp. 171-218
-
-
Gröger, D.1
Floss, H.G.2
-
95
-
-
20444414907
-
The ergot alkaloid gene cluster in Claviceps purpurea: Extension of the cluster sequence and intra species evolution
-
Haarmann T, Machado C, Lubbe Y, Correia T, Schardl CL, Panaccione DG et al. The ergot alkaloid gene cluster in Claviceps purpurea: extension of the cluster sequence and intra species evolution. Phytochemistry 2005; 66: 1312-20.
-
(2005)
Phytochemistry
, vol.66
, pp. 1312-1320
-
-
Haarmann, T.1
Machado, C.2
Lubbe, Y.3
Correia, T.4
Schardl, C.L.5
Panaccione, D.G.6
-
96
-
-
24944512693
-
Origins and significance of ergot alkaloid diversity in fungi
-
Panaccione DG. Origins and significance of ergot alkaloid diversity in fungi. FEMS Microbiol Lett 2005; 251: 9-17.
-
(2005)
FEMS Microbiol Lett
, vol.251
, pp. 9-17
-
-
Panaccione, D.G.1
-
97
-
-
0025193843
-
-
Lawen A, Zocher R. Cyclosporin synthetase. The most complex peptide synthesizing multienzyme polypeptide so far described. J Biol Chem 1990; 265: 1355-60.
-
Lawen A, Zocher R. Cyclosporin synthetase. The most complex peptide synthesizing multienzyme polypeptide so far described. J Biol Chem 1990; 265: 1355-60.
-
-
-
-
98
-
-
0025064915
-
Isolation and partial characterization of cyclosporin synthetase from a cyclosporin non-producing mutant of Beauveria nivea
-
Dittmann J, Lawen A, Zocher R, Kleinkauf H. Isolation and partial characterization of cyclosporin synthetase from a cyclosporin non-producing mutant of Beauveria nivea. Biol Chem Hoppe-Seyler 1990; 371: 829-34.
-
(1990)
Biol Chem Hoppe-Seyler
, vol.371
, pp. 829-834
-
-
Dittmann, J.1
Lawen, A.2
Zocher, R.3
Kleinkauf, H.4
-
99
-
-
0028284699
-
The peptide synthetase catalyzing cyclosporine production in Tolypocladium niveum is encoded by a giant 45.8-kilobase open reading frame
-
Weber G, Schörgendorfer K, Schneider-Scherzer E, Leitner E. The peptide synthetase catalyzing cyclosporine production in Tolypocladium niveum is encoded by a giant 45.8-kilobase open reading frame. Curr Genet 1994; 26: 120-5.
-
(1994)
Curr Genet
, vol.26
, pp. 120-125
-
-
Weber, G.1
Schörgendorfer, K.2
Schneider-Scherzer, E.3
Leitner, E.4
-
100
-
-
0033591447
-
Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis
-
Kennedy J, Auclair K, Kendrew SG, Park C, Vederas JC, Hutchinson CR. Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis. Science 1999; 284: 368-72.
-
(1999)
Science
, vol.284
, pp. 368-372
-
-
Kennedy, J.1
Auclair, K.2
Kendrew, S.G.3
Park, C.4
Vederas, J.C.5
Hutchinson, C.R.6
-
101
-
-
0036321084
-
Molecular cloning and characterization of an ML-236B (compactin) biosynthetic gene cluster in Penicillium citrinum
-
Abe Y, Suzuki T, Ono C, Iwamoto K, Hosobuchi M, Yoshikawa H. Molecular cloning and characterization of an ML-236B (compactin) biosynthetic gene cluster in Penicillium citrinum. Mol Gen Genet 2002; 267: 636-46.
-
(2002)
Mol Gen Genet
, vol.267
, pp. 636-646
-
-
Abe, Y.1
Suzuki, T.2
Ono, C.3
Iwamoto, K.4
Hosobuchi, M.5
Yoshikawa, H.6
-
102
-
-
28844461287
-
Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae
-
Galagan JE, Calvo SE, Cuomo C, Ma LJ, Wortman JR, Batzoglou S et al. Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae. Nature 2005; 438: 1105-15.
-
(2005)
Nature
, vol.438
, pp. 1105-1115
-
-
Galagan, J.E.1
Calvo, S.E.2
Cuomo, C.3
Ma, L.J.4
Wortman, J.R.5
Batzoglou, S.6
-
103
-
-
28644434509
-
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
-
Nierman WC, Pain A, Anderson MJ, Wortman JR, Kim HS, Arroyo J et al. Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature 2005; 438: 1151-6.
-
(2005)
Nature
, vol.438
, pp. 1151-1156
-
-
Nierman, W.C.1
Pain, A.2
Anderson, M.J.3
Wortman, J.R.4
Kim, H.S.5
Arroyo, J.6
-
104
-
-
29244442741
-
Genome sequencing and analysis of Aspergillus oryzae
-
Machida M, Asai K, Sano M, Tanaka T, Kumagai T, Terai G et al. Genome sequencing and analysis of Aspergillus oryzae. Nature 2005; 438: 1157-61.
-
(2005)
Nature
, vol.438
, pp. 1157-1161
-
-
Machida, M.1
Asai, K.2
Sano, M.3
Tanaka, T.4
Kumagai, T.5
Terai, G.6
-
105
-
-
30744456748
-
Genomic mining for Aspergillus natural products
-
Bok JW, Hoffmeister D, Maggio-Hall LA, Murillo R, Glasner JD, Keller NP. Genomic mining for Aspergillus natural products. Chem Biol 2006; 13: 31-7.
-
(2006)
Chem Biol
, vol.13
, pp. 31-37
-
-
Bok, J.W.1
Hoffmeister, D.2
Maggio-Hall, L.A.3
Murillo, R.4
Glasner, J.D.5
Keller, N.P.6
-
106
-
-
34250363005
-
Discovery of aspoquinolones A-D, prenylated quinoline-2-one alkaloids from Aspergillus nidulans, motivated by genome mining
-
Scherlach K, Hertweck C. Discovery of aspoquinolones A-D, prenylated quinoline-2-one alkaloids from Aspergillus nidulans, motivated by genome mining. Org Biomol Chem 2006; 45: 7835-8.
-
(2006)
Org Biomol Chem
, vol.45
, pp. 7835-7838
-
-
Scherlach, K.1
Hertweck, C.2
-
107
-
-
15244357386
-
Functional analysis of all nonribosomal peptide synthetases in Cochliobolus heterostrophus reveals a factor, NPS6, involved in virulence and resistance to oxidative stress
-
Lee BN, Kroken S, Chou DY, Robbertse B, Yoder OC, Turgeon BG. Functional analysis of all nonribosomal peptide synthetases in Cochliobolus heterostrophus reveals a factor, NPS6, involved in virulence and resistance to oxidative stress. Euk Cell 2005; 4: 545-55.
-
(2005)
Euk Cell
, vol.4
, pp. 545-555
-
-
Lee, B.N.1
Kroken, S.2
Chou, D.Y.3
Robbertse, B.4
Yoder, O.C.5
Turgeon, B.G.6
-
108
-
-
2442629464
-
The diploid genome sequence of Candida albicans
-
Jones T, Federspiel NA, Chibana H, Dungan J, Kalman S, Magee BB et al. The diploid genome sequence of Candida albicans. Proc Natl Acad Sci USA 2004; 101: 7329-34.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 7329-7334
-
-
Jones, T.1
Federspiel, N.A.2
Chibana, H.3
Dungan, J.4
Kalman, S.5
Magee, B.B.6
-
109
-
-
77955617560
-
A human-curated annotation of the Candida albicans genome
-
Braun BR, van Het Hoog M, d'Enfert C, Martchenko M, Dungan J, Kuo A et al. A human-curated annotation of the Candida albicans genome. PLoS Genet 2005; 1: E1.
-
(2005)
PLoS Genet
, vol.1
-
-
Braun, B.R.1
van Het Hoog, M.2
d'Enfert, C.3
Martchenko, M.4
Dungan, J.5
Kuo, A.6
-
110
-
-
0035103447
-
An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans
-
De Backer MD, Nelissen B, Logghe M, Viaene J, Loonen I, Vandoninck S et al. An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans. Nat Biotechnol 2001; 19: 212-3.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 212-213
-
-
De Backer, M.D.1
Nelissen, B.2
Logghe, M.3
Viaene, J.4
Loonen, I.5
Vandoninck, S.6
-
111
-
-
0141594783
-
Progress in functional genomics approaches to antifungal drug target discovery
-
De Backer MD, Van Dijck P. Progress in functional genomics approaches to antifungal drug target discovery. Trends Microbiol 2003; 11: 470-8.
-
(2003)
Trends Microbiol
, vol.11
, pp. 470-478
-
-
De Backer, M.D.1
Van Dijck, P.2
|