Protonation patterns in tetracycline:tet repressor recognition: Simulations and experiments

ChemBioChem

Volumn 8, Issue 6, 2007, Pages 675-685

  Aleksandrov, Alexey ^a   Proft, Juliane ^b   Hinrichs, Winfried ^b   Simonson, Thomas ^a  

^a LABORATOIRE DE BIOCHIMIE   (France)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Antibiotics; Molecular dynamics; Molecular recognition; Protein structures; Tetracycline binding

Indexed keywords

AMIDE; AMMONIUM DERIVATIVE; IMIDAZOLE DERIVATIVE; LIGAND; MAGNESIUM ION; REPRESSOR PROTEIN; TETRACYCLINE; PROTON; TETRACYCLINE RESISTANCE ENCODING TRANSPOSON REPRESSOR PROTEIN; TETRACYCLINE RESISTANCE-ENCODING TRANSPOSON REPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; DRUG BINDING; DRUG DESIGN; DRUG STRUCTURE; GENE CONTROL; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTON TRANSPORT; REPRESSOR GENE; SIMULATION; X RAY CRYSTALLOGRAPHY; ALGORITHM; ANTIBIOTIC RESISTANCE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; GENETICS; PHYSICAL CHEMISTRY; STRUCTURE ACTIVITY RELATION;

ALGORITHMS; CHEMISTRY, PHYSICAL; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; LIGANDS; MODELS, MOLECULAR; PROTONS; REPRESSOR PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TETRACYCLINE; TETRACYCLINE RESISTANCE;

EID: 34250371374     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200600535     Document Type: Article

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