Evaluation of in vitro aldose redutase inhibitory activity of 5-arylidene-2,4-thiazolidinediones

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 14, 2007, Pages 3886-3893

  Maccari, Rosanna ^a   Ottanà, Rosaria ^a   Ciurleo, Rosella ^a   Vigorita, Maria Gabriella ^a   Rakowitz, Dietmar ^b   Steindl, Theodora ^b   Langer, Thierry ^b  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

2,4 Thiazolidinediones; Aldose reductase; Diabetes mellitus; Molecular docking

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; AMINO ACID; CARBOXYL GROUP; LEUCINE; PHENOL;

ARTICLE; CONCENTRATION RESPONSE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; LIPOPHILICITY; MOLECULAR DOCKING; REACTION ANALYSIS; SIMULATION; STRUCTURE ANALYSIS;

ALDEHYDE REDUCTASE; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; MODELS, MOLECULAR; THIAZOLIDINEDIONES;

EID: 34250337361     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.04.109     Document Type: Article

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