In vitro aldose reductase inhibitory activity of 5-benzyl-2,4- thiazolidinediones

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 2, 2006, Pages 567-574

  Rakowitz, Dietmar ^a   Maccari, Rosanna ^b   Ottanà, Rosaria ^b   Vigorita, Maria Gabriella ^b  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b UNIVERSITY OF MESSINA   (Italy)

Author keywords

2,4 Thiazolidinediones; Aldose reductase; ALR2 inhibitors; Structure activity relationships

Indexed keywords

(5 BIPHENYL 4 YLMETHYL 2,4 DIOXOTHIAZOLIDIN 3 YL)ACETIC ACID; (5 BIPHENYL 4 YLMETHYL 2,4 DIOXOTHIAZOLIDIN 3 YL)ACETIC ACID METHYL ESTER; 2,4 THIAZOLIDINEDIONE DERIVATIVE; 5 (3 METHOXYBENZYL) 2,4 THIAZOLIDINEDIONE; 5 (3 PHENOXYBENZYL) 2,4 THIAZOLIDINEDIONE; 5 (4 BENZYLOXYBENZYL) 2,4 THIAZOLINEDIONE; 5 (4 METHOXYBENZYL) 2,4 THIAZOLIDINEDIONE; 5 (4 PHENOXYBENZYL) 2,4 THIAZOLIDINEDIONE; 5 BIPHENYL 4 YLMETHYL 2,4 THIAZOLIDINEDIONE; [2,4 DIOXO 5 (3 PHENOXYBENZYL)THIAZOLIDIN 3 YL]ACETIC ACID; [2,4 DIOXO 5 (3 PHENOXYBENZYL)THIAZOLIDIN 3 YL]ACETIC ACID METHYL ESTER; [2,4 DIOXO 5 (4 PHENOXYBENZYL)THIAZOLIDIN 3 YL]ACETIC ACID; [2,4 DIOXO 5 (4 PHENOXYBENZYL)THIAZOLIDIN 3 YL]ACETIC ACID METHYL ESTER; [5 (3 METHOXYBENZYL) 2,4 DIOXOTHIAZOLIDIN 3 YL]ACETIC ACID; [5 (3 METHOXYBENZYL) 2,4 DIOXOTHIAZOLIDIN 3 YL]ACETIC ACID METHYL ESTER; [5 (4 BENZYLOXYBENZYL) 2,4 DIOXOTHIAZOLIDIN 3 YL]ACETIC ACID METHYL ESTER; [5 (4 HYDROXYBENZYL) 2,4 DIOXOTHIAZOLIDIN 3 YL]ACETIC ACID; [5 (4 METHOXYBENZYL) 2,4 DIOXOTHIAZOLIDIN 3 YL]ACETIC ACID; [5 (4 METHOXYBENZYL) 2,4 DIOXOTHIAZOLIDIN 3 YL]ACETIC ACID METHYL ESTER; ACETIC ACID; ALDOSE REDUCTASE INHIBITOR; PONALRESTAT; SORBINIL; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; SUBSTITUTION REACTION;

ALDEHYDE REDUCTASE; ENZYME INHIBITORS; MAGNETIC RESONANCE SPECTROSCOPY; THIAZOLIDINEDIONES;

EID: 28844489963     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.08.056     Document Type: Article

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