Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-I-deficient mice

Molecular Neurodegeneration

Volumn 2, Issue 1, 2007, Pages

  Yamaguchi, Hiroo ^a   Shen, Jie ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUS;

EID: 34250334136     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/1750-1326-2-10     Document Type: Article

References (43)

1. Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, Minoshima S, Yokochi M, Mizuno Y, Shimizu N: Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998, 392(6676):605- 608.
2. Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, Krieger E, Dekker MC, Squitieri F, Ibanez P, Joosse M, van Dongen JW, Vanacore N, van Swieten JC, Brice A, Meco G, van Duijn CM, Oostra BA, Heutink P: Mutations in the DJ-I gene associated with autosomal recessive early-onset parkinsonism. Science 2003, 299(5604):256-259.
3. Valente EM, Abou-Sleiman PM, Caputo V, Muqit MM, Harvey K, Gispert S, Ali Z, Del Turco D, Bentivoglio AR, Healy DG, Albanese A, Nussbaum R, Gonzalez-Maldonado R, Deller T, Salvi S, Cortelli P, Gilks WP, Latchman DS, Harvey RJ, Dallapiccola B, Auburger G, Wood NW: Hereditary early-onset Parkinson's disease caused by mutations in PINKI. Science 2004, 304(5674):1158-1160.
4. Goldberg MS, Pisani A, Haburcak M, Vortherms TA, Kitada T, Costa C, Tong Y, Martella G, Tscherter A, Martins A, Bernardi G, Roth BL, Pothos EN, Calabresi P, Shen J: Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-I. Neuron 2005, 45(4):489-496.
5. Taira T, Saito Y, Niki T, Iguchi-Ariga SM, Takahashi K, Ariga H: DJ-I has a role in antioxidative stress to prevent cell death. EMBO Rep 2004, 5(2):213-218.
6. Canet-Aviles RM, Wilson MA, Miller DW, Ahmad R, McLendon C, Bandyopadhyay S, Baptista MJ, Ringe D, Petsko GA, Cookson MR: The Parkinson's disease protein DJ-I is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc Natl Acad Sci U S A 2004, 101(24):9103-9108.
7. Kinumi T, Kimata J, Taira T, Ariga H, Niki E: Cysteine-106 of DJ-I is the most sensitive cysteine residue to hydrogen peroxide-mediated oxidation in vivo in human umbilical vein endothelial cells. Biochem Biophys Res Commun 2004, 317(3):722-728.
8. Menzies FM, Yenisetti SC, Min KT: Roles of Drosophila DJ-I in survival of dopaminergic neurons and oxidative stress. Curr Biol 2005, 15(17):1578-1582.
9. Meulener M, Whitworth AJ, Armstrong-Gold CE, Rizzu P, Heutink P, Wes PD, Pallanck LJ, Bonini NM: Drosophila DJ-I mutants are selectively sensitive to environmental toxins associated with Parkinson's disease. Curr Biol 2005, 15(17):1572-1577.
10. Martinat C, Shendelman S, Jonason A, Leete T, Beal MF, Yang L, Floss T, Abeliovich A: Sensitivity to oxidative stress in DJ-I-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism. PLoS Biol 2004, 2(11):e327.
11. Takahashi-Niki K, Niki T, Taira T, Iguchi-Ariga SM, Ariga H: Reduced anti-oxidative stress activities of DJ-I mutants found in Parkinson's disease patients. Biochem Biophys Res Commun 2004, 320(2):389-397.
12. Clements CM, McNally RS, Conti BJ, Mak TW, Ting JP: DJ-I, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proc Natl Acad Sci U S A 2006, 103(41 ):15091-15096.
13. Shendelman S, Jonason A, Martinat C, Leete T, Abeliovich A: DJ-I is a redox-dependent molecular chaperone that inhibits alphasynuclein aggregate formation. PLoS Biol 2004, 2(11):e362.
14. Xu J, Zhong N, Wang H, Elias JE, Kim CY, Woldman I, Pifl C, Gygi SP, Geula C, Yankner BA: The Parkinson's disease-associated DJ-I protein is a transcriptional co-activator that protects against neuronal apoptosis. Hum Mol Genet 2005, 14(9):1231-1241.
15. Karam LR, Bergtold DS, Simic MG: Biomarkers of OH radical damage in vivo. Free Radic Res Commun 1991, 12-13 Pt 1:11-16.
16. Halliwell B: Reactive oxygen species and the central nervous system. J Neurochem 1992, 59(5):1609-1623.
17. Lotharius J, Brundin P: Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein. Nat Rev Neurosci 2002, 3(12):932-942.
18. Nakabeppu Y, Tsuchimoto D, Yamaguchi H, Sakumi K: Oxidative damage in nucleic acids and Parkinson's disease. J Neurosci Res 2007, 85(5):919-934.
19. Moore DJ, Zhang L, Troncoso J, Lee MK, Hattori N, Mizuno Y, Dawson TM, Dawson VL: Association of DJ-I and parkin mediated by pathogenic DJ-I mutations and oxidative stress. Hum Mol Genet 2005, 14(1):71-84.
20. Waragai M, Wei J, Fujita M, Nakai M, Ho GJ, Masliah E, Akatsu H, Yamada T, Hashimoto M: Increased level of DJ-I in the cerebro-spinal fluids of sporadic Parkinson's disease. Biochem Biophys Res Commun 2006, 345(3):967-972.
21. Choi J, Sullards MC, Olzmann JA, Rees HD, Weintraub ST, Bostwick DE, Gearing M, Levey AI, Chin LS, Li L: Oxidative damage of DJ-I is linked to sporadic Parkinson and Alzheimer diseases. J Biol Chem 2006, 281(16):10816-10824.
22. Yokota T, Sugawara K, Ito K, Takahashi R, Ariga H, Mizusawa H: Down regulation of DJ-I enhances cell death by oxidative stress, ER stress, and proteasome inhibition. Biochem Biophys Res Commun 2003, 312(4):1342-1348.
23. Kim RH, Smith PD, Aleyasin H, Hayley S, Mount MP, Pownall S, Wakeham A, You-Ten AJ, Kalia SK, Home P, Westaway D, Lozano AM, Anisman H, Park DS, Mak TW: Hypersensitivity of DJ-1 -deficient mice to I-methyl-4-phenyl-1,2,3,6- tetrahydropyrindine (MPTP) and oxidative stress. Proc Natl Acad Sci U S A 2005, 102(14):52I5-5220.
24. Zhou W, Freed CR: DJ-I up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity. J Biol Chem 2005, 280(52):43150-43158.
25. Inden M, Taira T, Kitamura Y, Yanagida T, Tsuchiya D, Takata K, Yanagisawa D, Nishimura K, Taniguchi T, Kiso Y, Yoshimoto K, Agatsuma T, Koide-Yoshida S, Iguchi-Ariga SM, Shimohama S, Ariga H: PARK7 DJ-I protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model. Neurobiol Dis 2006.
26. Yang Y, Gehrke S, Haque ME, Imai Y, Kosek J, Yang L, Beal MF, Nishimura I, Wakamatsu K, Ito S, Takahashi R, Lu B: Inactivation of Drosophila DJ-I leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc Natl Acad Sci U S A 2005, 102(38): 13670-13675.
27. Bakshi VP, Geyer MA: Phencyclidine-induced deficits in prepulse inhibition of startle are blocked by prazosin, an alphaI noradrenergic antagonist. J Pbarmacol Exp Ther 1997, 283(2):666-674.
28. Saitoh K, Shaw S, Tilson HA: Noradrenergic influence on the prepulse inhibition of acoustic startle. Toxicol Lett 1986, 34(2-3):209-2I6.
29. Toufexis DJ, Rochford J, Walker CD: Lactation-induced reduction in rats' acoustic startle is associated with changes in noradrenergic neurotransmission. Behav Neurosci 1999, 113(1):176-184.
30. Kotaria N, Hinz U, Zechel S, von Bohlen Und Halbach O: Localization of DJ-I protein in the murine brain. Cell Tissue Res 2005, 322(3):503-507.
31. Bandopadhyay R, Kingsbury AE, Cookson MR, Reid AR, Evans IM, Hope AD, Pittman AM, Lashley T, Canet-Aviles R, Miller DW, McLendon C, Strand C, Leonard AJ, Abou-Sleiman PM, Healy DG, Ariga H, Wood NW, de Silva R, Revesz T, Hardy JA, Lees AJ: The expression of DJ-I (PARK7) in normal human CMS and idiopathic Parkinson's disease. Brain 2004, 127(Pt 2):420-430.
32. Shimura-Miura H, Hattori N, Kang D, Miyako K, Nakabeppu Y, Mizuno Y: Increased 8-oxo-dGTPase in the mitochondria of substantia nigral neurons in Parkinson's disease. Ann Neural 1999, 46(6):920-924.
33. Yamaguchi H, Kajitani K, Dan Y, Furuichi M, Ohno M, Sakumi K, Kang D, Nakabeppu Y: MTHI, an oxidized purine nucleoside triphosphatase, protects the dopamine neurons from oxidative damage in nucleic acids caused by I-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Cell Death Differ 2006, 13(4):551-563.
34. Castellani RJ, Perry G, Siedlak SL, Nunomura A, Shimohama S, Zhang J, Montine T, Sayre LM, Smith MA: Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brain-stem Lewy bodies in humans. Neurosci Lett 2002, 319(1):25-28.
35. Good PF, Hsu A, Werner P, Perl DP, Olanow CW: Protein nitration in Parkinson's disease. J Neuropathol Exp Neural 1998, 57(4):338-342.
36. Von Coelln R, Thomas B, Savitt JM, Lim KL, Sasaki M, Hess EJ, Dawson VL, Dawson TM: Loss of locus coeruleus neurons and reduced startle in parkin null mice. Proc Natl Acad Sci U S A 2004, 101(29):10744-10749.
37. Betarbet R, Sherer TB, MacKenzie G, Garcia-Osuna M, Panov AV, Greenamyre JT: Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 2000, 3(12):1301-1306.
38. Fornai F, Schluter OM, Lenzi P, Gesi M, Ruffoli R, Ferrucci M, Lazzeri G, Busceti CL, Pontarelli F, Battaglia G, Pellegrini A, Nicoletti F, Ruggieri S, Paparelli A, Sudhof TC: Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein. Proc Natl Acad Sci U S A 2005, 102(9):3413- 3418.
39. Zhong N, Kim CY, Rizzu P, Geula C, Porter DR, Pothos EN, Squitieri F, Heutink P, Xu J: DJ-I transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor, J Biol Chem 2006, 281 (30):20940-20948.
40. Goldberg MS, Fleming SM, Palacino JJ, Cepeda C, Lam HA, Bhatnagar A, Meloni EG, Wu N, Ackerson LC, Klapstein GJ, Gajendiran M, Roth BL, Chesselet MF, Maidment NT, Levine MS, Shen J: Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons, J Biol Chem 2003, 278(44):43628-43635.
41. Sterio DC: The unbiased estimation of number and sizes of arbitrary particles using the disector. J Microsc 1984, 134(Pt 2):127-136.
42. German DC, Liang CL, Manaye KF, Lane K, Sonsalla PK: Pharmacological inactivation of the vesicular monoamine transporter can enhance I-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration of midbrain dopaminergic neurons, but not locus coeruleus noradrenergic neurons. Neuroscience 2000, 101(4):1063-1069.
43. German DC, Nelson O, Liang F, Liang CL, Games D: The PDAPP mouse model of Alzheimer's disease: locus coeruleus neuronal shrinkage. J Comp Neurol 2005, 492(4):469-476.