Thapsigargin, a selective inhibitor of sarco-endoplasmic reticulum Ca 2+-ATPases, modulates nitric oxide production and cell death of primary rat hepatocytes in culture

Cell Biology and Toxicology

Volumn 23, Issue 5, 2007, Pages 337-354

  Canová, N Kutinová ^a   Kmonickova E ^b   Martinek J ^a   Zidek Z ^b   Farghali, H ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

Author keywords

Apoptosis; Intracellular free calcium; Necrosis; Nitric oxide; Rat hepatocytes; Thapsigargin

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); AMINOGUANIDINE; CALCIUM ION; CASPASE 3; CYTOCHROME C; DNA FRAGMENT; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOCORTIN 5; NITRIC OXIDE; PROPIDIUM IODIDE; THAPSIGARGIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOCHEMISTRY; CALCIUM CELL LEVEL; CALCIUM DEPLETION; CELL CULTURE; CELL DEATH; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; INCUBATION TIME; LIVER CELL; MALE; MITOCHONDRION; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SARCOPLASMIC RETICULUM;

ANIMALS; APOPTOSIS; CALCIUM; CASPASE 3; CELL DEATH; CELL NUCLEUS; CELLS, CULTURED; GUANIDINES; HEPATOCYTES; MITOCHONDRIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; RATS; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; THAPSIGARGIN;

RATTUS;

EID: 34250331487     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10565-007-0185-6     Document Type: Article

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