메뉴 건너뛰기




Volumn 102, Issue 1, 2007, Pages 133-140

p25/Cyclin-dependent kinase 5 promotes the progression of cell death in nucleus of endoplasmic reticulum-stressed neurons

Author keywords

Calpain; Cyclin dependent kinase 5; Endoplasmic reticulum stress; Neurodegenerative disease; Neuronal cell death; Nuclear translocation

Indexed keywords

CALPAIN; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE INHIBITOR; PROTEIN P25; PROTEIN P35;

EID: 34250200796     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.04540.x     Document Type: Article
Times cited : (52)

References (42)
  • 1
    • 1542381057 scopus 로고    scopus 로고
    • Cell cycle regulation of neuronal apoptosis in development and disease
    • Becker E. B. Bonni A. (2004) Cell cycle regulation of neuronal apoptosis in development and disease. Prog. Neurobiol. 72, 1 25.
    • (2004) Prog. Neurobiol. , vol.72 , pp. 1-25
    • Becker, E.B.1    Bonni, A.2
  • 2
    • 0345405447 scopus 로고    scopus 로고
    • Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles
    • Cruz J. C., Tseng H. C., Goldman J. A., Shih H. Tsai L. H. (2003) Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles. Neuron 30, 471 483.
    • (2003) Neuron , vol.30 , pp. 471-483
    • Cruz, J.C.1    Tseng, H.C.2    Goldman, J.A.3    Shih, H.4    Tsai, L.H.5
  • 4
    • 0142090441 scopus 로고    scopus 로고
    • 'Unfolding' pathways in neurodegenerative disease
    • Forman M. S., Lee V. M. Trojanowski J. Q. (2003) 'Unfolding' pathways in neurodegenerative disease. Trends Neurosci. 26, 407 410.
    • (2003) Trends Neurosci. , vol.26 , pp. 407-410
    • Forman, M.S.1    Lee, V.M.2    Trojanowski, J.Q.3
  • 5
    • 0037431130 scopus 로고    scopus 로고
    • Cdk5-mediated inhibition of the protective effects of transcription factor MEF2 in neurotoxicity-induced apoptosis
    • Gong X., Tang X., Wiedmann M., Wang X., Peng J., Zheng D., Blair L. A., Marshall J. Mao Z. (2003) Cdk5-mediated inhibition of the protective effects of transcription factor MEF2 in neurotoxicity-induced apoptosis. Neuron 38, 33 46.
    • (2003) Neuron , vol.38 , pp. 33-46
    • Gong, X.1    Tang, X.2    Wiedmann, M.3    Wang, X.4    Peng, J.5    Zheng, D.6    Blair, L.A.7    Marshall, J.8    Mao, Z.9
  • 6
    • 0347785492 scopus 로고    scopus 로고
    • Truncation of CDK5 activator p35 induces intensive phosphorylation of Ser202/Thr205 of human tau
    • Hashiguchi M., Saito T., Hisanaga S. Hashiguchi T. (2002) Truncation of CDK5 activator p35 induces intensive phosphorylation of Ser202/Thr205 of human tau. J. Biol. Chem. 277, 44 525 44 530.
    • (2002) J. Biol. Chem. , vol.277 , pp. 44525-44530
    • Hashiguchi, M.1    Saito, T.2    Hisanaga, S.3    Hashiguchi, T.4
  • 7
    • 0348010572 scopus 로고    scopus 로고
    • The regulation of cyclin-dependent kinase 5 activity through the metabolism of p35 or p39 Cdk5 activator
    • Hisanaga S. Saito T. (2003) The regulation of cyclin-dependent kinase 5 activity through the metabolism of p35 or p39 Cdk5 activator. Neurosignals 12, 221 229.
    • (2003) Neurosignals , vol.12 , pp. 221-229
    • Hisanaga, S.1    Saito, T.2
  • 9
    • 1242269804 scopus 로고    scopus 로고
    • Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12
    • Hitomi J., Katayama T., Taniguchi M., Honda A., Imaizumi K. Tohyama M. (2004) Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12. Neurosci. Lett. 357, 127 130.
    • (2004) Neurosci. Lett. , vol.357 , pp. 127-130
    • Hitomi, J.1    Katayama, T.2    Taniguchi, M.3    Honda, A.4    Imaizumi, K.5    Tohyama, M.6
  • 10
    • 0030565507 scopus 로고    scopus 로고
    • Intracellular localization of cyclin-dependent kinase 5 (CDK5) in mouse neuron: CDK5 is located in both nucleus and cytoplasm
    • Ino H. Chiba T. (1996) Intracellular localization of cyclin-dependent kinase 5 (CDK5) in mouse neuron: CDK5 is located in both nucleus and cytoplasm. Brain Res. 732, 179 185.
    • (1996) Brain Res. , vol.732 , pp. 179-185
    • Ino, H.1    Chiba, T.2
  • 11
    • 0029618170 scopus 로고
    • Analysis of phosphorylation of tau with antibodies specific for phosphorylation sites
    • Ishiguro K., Sato K., Takamatsu M., Park J., Uchida T. Imahori K. (1995) Analysis of phosphorylation of tau with antibodies specific for phosphorylation sites. Neurosci. Lett. 202, 81 84.
    • (1995) Neurosci. Lett. , vol.202 , pp. 81-84
    • Ishiguro, K.1    Sato, K.2    Takamatsu, M.3    Park, J.4    Uchida, T.5    Imahori, K.6
  • 12
    • 0033258544 scopus 로고    scopus 로고
    • Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response
    • Katayama T., Imaizumi K., Sato N. et al. (1999) Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response. Nat. Cell Biol. 8, 479 485.
    • (1999) Nat. Cell Biol. , vol.8 , pp. 479-485
    • Katayama, T.1    Imaizumi, K.2    Sato, N.3
  • 13
    • 0033562966 scopus 로고    scopus 로고
    • Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls
    • Kaufman R. J. (1999) Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev. 13, 1211 1233.
    • (1999) Genes Dev. , vol.13 , pp. 1211-1233
    • Kaufman, R.J.1
  • 14
    • 0036434290 scopus 로고    scopus 로고
    • Cleavage of the cyclin-dependent kinase 5 activator p35 to p25 does not induce tau hyperphosphorylation
    • Kerokoski P., Suuronen T., Salminen A., Soininen H. Pirttila T. (2002) Cleavage of the cyclin-dependent kinase 5 activator p35 to p25 does not induce tau hyperphosphorylation. Biochem. Biophys. Res. Commun. 298, 693 698.
    • (2002) Biochem. Biophys. Res. Commun. , vol.298 , pp. 693-698
    • Kerokoski, P.1    Suuronen, T.2    Salminen, A.3    Soininen, H.4    Pirttila, T.5
  • 15
    • 0034595834 scopus 로고    scopus 로고
    • Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25
    • Kusakawa G., Saito T., Onuki R., Ishiguro K., Kishimoto T. Hisanaga S. (2000) Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25. J. Biol. Chem. 275, 17 166 17 172.
    • (2000) J. Biol. Chem. , vol.275 , pp. 17166-17172
    • Kusakawa, G.1    Saito, T.2    Onuki, R.3    Ishiguro, K.4    Kishimoto, T.5    Hisanaga, S.6
  • 16
    • 0026843954 scopus 로고
    • Mammalian stress response: Induction of the glucose-regulated protein family
    • Lee A. S. (1992) Mammalian stress response: induction of the glucose-regulated protein family. Curr. Opin. Cell Biol. 4, 267 273.
    • (1992) Curr. Opin. Cell Biol. , vol.4 , pp. 267-273
    • Lee, A.S.1
  • 17
    • 0031054972 scopus 로고    scopus 로고
    • Neuronal Cdc2-like kinase (Nclk) binds and phosphorylates the retinoblastoma protein
    • Lee K. Y., Helbing C. C., Choi K. S., Johnston R. N. Wang J. H. (1997) Neuronal Cdc2-like kinase (Nclk) binds and phosphorylates the retinoblastoma protein. J. Biol. Chem. 272, 5622 5626.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5622-5626
    • Lee, K.Y.1    Helbing, C.C.2    Choi, K.S.3    Johnston, R.N.4    Wang, J.H.5
  • 19
    • 33745039466 scopus 로고    scopus 로고
    • Nitric oxide, cell bioenergetics and neurodegeneration
    • Moncada S. Bolanos J. P. (2006) Nitric oxide, cell bioenergetics and neurodegeneration. J. Neurochem. 97, 1676 1689.
    • (2006) J. Neurochem. , vol.97 , pp. 1676-1689
    • Moncada, S.1    Bolanos, J.P.2
  • 20
    • 0034716887 scopus 로고    scopus 로고
    • Tripartite management of unfolded proteins in the endoplasmic reticulum
    • Mori K. (2000) Tripartite management of unfolded proteins in the endoplasmic reticulum. Cell 101, 451 454.
    • (2000) Cell , vol.101 , pp. 451-454
    • Mori, K.1
  • 21
    • 0034698878 scopus 로고    scopus 로고
    • Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
    • Nakagawa T. Yuan J. (2000) Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J. Cell Biol. 150, 887 894.
    • (2000) J. Cell Biol. , vol.150 , pp. 887-894
    • Nakagawa, T.1    Yuan, J.2
  • 22
    • 0029317904 scopus 로고
    • Cyclin-dependent protein kinases: Key regulators of the eukaryotic cell cycle
    • Nigg E. A. (1995) Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle. Bioessays 17, 471 480.
    • (1995) Bioessays , vol.17 , pp. 471-480
    • Nigg, E.A.1
  • 23
    • 0029966469 scopus 로고    scopus 로고
    • The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation
    • Nikolic M., Dudek H., Kwon Y. T., Ramos Y. F. Tsai L. H. (1996) The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation. Genes Dev. 10, 816 825.
    • (1996) Genes Dev. , vol.10 , pp. 816-825
    • Nikolic, M.1    Dudek, H.2    Kwon, Y.T.3    Ramos, Y.F.4    Tsai, L.H.5
  • 24
    • 0038689162 scopus 로고    scopus 로고
    • Cdk5 is a key factor in tau aggregation and tangle formation in vivo
    • Noble W., Olm V., Takata K. et al. (2003) Cdk5 is a key factor in tau aggregation and tangle formation in vivo. Neuron 38, 555 565.
    • (2003) Neuron , vol.38 , pp. 555-565
    • Noble, W.1    Olm, V.2    Takata, K.3
  • 26
    • 1842562209 scopus 로고    scopus 로고
    • An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease
    • Onuki R., Bando Y., Suyama E., Katayama T., Kawasaki H., Baba T., Tohyama M. Taira K. (2004) An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease. EMBO J. 23, 959 968.
    • (2004) EMBO J. , vol.23 , pp. 959-968
    • Onuki, R.1    Bando, Y.2    Suyama, E.3    Katayama, T.4    Kawasaki, H.5    Baba, T.6    Tohyama, M.7    Taira, K.8
  • 27
    • 0035684155 scopus 로고    scopus 로고
    • The Cdk5-p35 kinase associates with the Golgi apparatus and regulates membrane traffic
    • Paglini G., Peris L., Diez-Guerra J., Quiroga S. Caceres A. (2001) The Cdk5-p35 kinase associates with the Golgi apparatus and regulates membrane traffic. EMBO Rep. 2, 1139 1144.
    • (2001) EMBO Rep. , vol.2 , pp. 1139-1144
    • Paglini, G.1    Peris, L.2    Diez-Guerra, J.3    Quiroga, S.4    Caceres, A.5
  • 28
    • 0032508698 scopus 로고    scopus 로고
    • P35, the neuronal-specific activator of cyclin-dependant kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway
    • Patrick G. N., Zhou P., Kwon Y. T., Howley P. M. Tsai L. H. (1998) p35, the neuronal-specific activator of cyclin-dependant kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway. J. Biol. Chem. 273, 24057 24064.
    • (1998) J. Biol. Chem. , vol.273 , pp. 24057-24064
    • Patrick, G.N.1    Zhou, P.2    Kwon, Y.T.3    Howley, P.M.4    Tsai, L.H.5
  • 29
    • 0033540060 scopus 로고    scopus 로고
    • Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
    • Patrick G. N., Zukerberg L., Nikolic M., de la Monte S., Dikkes P. Tsai L. H. (1999) Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration. Nature 402, 615 622.
    • (1999) Nature , vol.402 , pp. 615-622
    • Patrick, G.N.1    Zukerberg, L.2    Nikolic, M.3    De La Monte, S.4    Dikkes, P.5    Tsai, L.H.6
  • 30
  • 31
    • 0037066724 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid beta-protein
    • Sai X., Kawamura Y., Kokame K. et al. (2002) Endoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid beta-protein. J. Biol. Chem. 277, 12 915 12 920.
    • (2002) J. Biol. Chem. , vol.277 , pp. 12915-12920
    • Sai, X.1    Kawamura, Y.2    Kokame, K.3
  • 33
    • 0037442786 scopus 로고    scopus 로고
    • Developmental regulation of the proteolysis of the p35 Cyclin-Dependent Kinase 5 Activator by Phosphorylation
    • Saito T., Onuki R., Fujita Y., Kusakawa G., Ishiguro K., Bibb J. A., Kishimoto T. Hisanaga S. (2003) Developmental regulation of the proteolysis of the p35 Cyclin-Dependent Kinase 5 Activator by Phosphorylation. J. Neurosci. 23, 1189 1197.
    • (2003) J. Neurosci. , vol.23 , pp. 1189-1197
    • Saito, T.1    Onuki, R.2    Fujita, Y.3    Kusakawa, G.4    Ishiguro, K.5    Bibb, J.A.6    Kishimoto, T.7    Hisanaga, S.8
  • 34
    • 24744462506 scopus 로고    scopus 로고
    • Phosphorylation of FTDP-17 mutant TAU by cyclin-dependent kinase 5 complexed with p35, p25, or p39
    • Sakaue F., Saito T., Sato Y., Asada A., Ishiguro K., Hasegawa M. Hisanaga S. (2005) Phosphorylation of FTDP-17 mutant TAU by cyclin-dependent kinase 5 complexed with p35, p25, or p39. J. Biol. Chem. 280, 31 522 31 529.
    • (2005) J. Biol. Chem. , vol.280 , pp. 31522-31529
    • Sakaue, F.1    Saito, T.2    Sato, Y.3    Asada, A.4    Ishiguro, K.5    Hasegawa, M.6    Hisanaga, S.7
  • 35
    • 1842532304 scopus 로고    scopus 로고
    • Effects of cyclin-dependent kinase-5 activity on apoptosis and tau phosphorylation in immortalized mouse brain cortical cells
    • Shelton S. B., Krishnamurthy P. Johnson G. V. (2004) Effects of cyclin-dependent kinase-5 activity on apoptosis and tau phosphorylation in immortalized mouse brain cortical cells. J. Neurosci. Res. 76, 110 120.
    • (2004) J. Neurosci. Res. , vol.76 , pp. 110-120
    • Shelton, S.B.1    Krishnamurthy, P.2    Johnson, G.V.3
  • 36
    • 0035976923 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-induced cysteine protease activation in cortical neurons: Effect of an Alzheimer's disease-linked presenilin-1 knock-in mutation
    • Siman R., Flood D. G., Thinakaran G. Neumar R. W. (2001) Endoplasmic reticulum stress-induced cysteine protease activation in cortical neurons: effect of an Alzheimer's disease-linked presenilin-1 knock-in mutation. J. Biol. Chem. 276, 44 736 44 743.
    • (2001) J. Biol. Chem. , vol.276 , pp. 44736-44743
    • Siman, R.1    Flood, D.G.2    Thinakaran, G.3    Neumar, R.W.4
  • 39
    • 0037125209 scopus 로고    scopus 로고
    • A survey of Cdk5 activator p35 and p25 levels in Alzheimer's disease brains
    • Tseng H. C., Zhou Y., Shen Y. Tsai L. H. (2002) A survey of Cdk5 activator p35 and p25 levels in Alzheimer's disease brains. FEBS Lett. 523, 58 62.
    • (2002) FEBS Lett. , vol.523 , pp. 58-62
    • Tseng, H.C.1    Zhou, Y.2    Shen, Y.3    Tsai, L.H.4
  • 40
    • 0027971397 scopus 로고
    • Precursor of cdk5 activator, the 23 kDa subunit of tau protein kinase II: Its sequence and developmental change in brain
    • Uchida T., Ishiguro K., Ohnuma J., Takamatsu M., Yonekura S. Imahori K. (1994) Precursor of cdk5 activator, the 23 kDa subunit of tau protein kinase II: its sequence and developmental change in brain. FEBS Lett. 355, 35 40.
    • (1994) FEBS Lett. , vol.355 , pp. 35-40
    • Uchida, T.1    Ishiguro, K.2    Ohnuma, J.3    Takamatsu, M.4    Yonekura, S.5    Imahori, K.6
  • 41
    • 0035859053 scopus 로고    scopus 로고
    • P25 protein in neurodegeneration
    • Yoo B. C. Lubec G. (2001) p25 protein in neurodegeneration. Nature 411, 763 764.
    • (2001) Nature , vol.411 , pp. 763-764
    • Yoo, B.C.1    Lubec, G.2
  • 42
    • 0036312755 scopus 로고    scopus 로고
    • Cdk5 phosphorylates p53 and regulates its activity
    • Zhang J., Krishnamurthy P. K. Johnson G. V. (2002) Cdk5 phosphorylates p53 and regulates its activity. J. Neurochem. 81, 307 313.
    • (2002) J. Neurochem. , vol.81 , pp. 307-313
    • Zhang, J.1    Krishnamurthy, P.K.2    Johnson, G.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.