Absolute quantification of four isoforms of the class I phosphoinositide-3-kinase catalytic subunit by real-time RT-PCR

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 6, 2007, Pages 1181-1184

  Nakamura, Hiroyuki ^a,b   Dan, Shingo ^a   Akashi, Tetsuyuki ^a   Unno, Michiaki ^b   Yamori, Takao ^a  

^a CANCER CHEMOTHERAPY CENTER   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Absolute quantification; Phosphoinositide 3 kinase (PI3K); Real time reverse transcription polymerase chain reaction (RT PCR); U937

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P110; PROTEIN P110 ALPHA; PROTEIN P110 BETA; PROTEIN P110 DELTA; PROTEIN P110 GAMMA; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN U937; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVE SITE; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; QUANTITATIVE ASSAY; REAL TIME POLYMERASE CHAIN REACTION; RELIABILITY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CATALYTIC DOMAIN; CELL LINE, TUMOR; ELECTROPHORESIS, AGAR GEL; GENE EXPRESSION; HUMANS; ISOENZYMES; PROTEIN STRUCTURE, TERTIARY; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; U937 CELLS;

EID: 34249998437     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.1181     Document Type: Article

References (44)

1. Hawkins P. T., Anderson K. E., Davidson K., Stephens L. R., Biochem. Soc. Trans., 34, 647-662 (2006).
2. Vanhaesebroeck B., Ali K., Bilancio A., Geering B., Foukas L. C., Trends. Biochem. Sci., 30, 194-204 (2005).
3. Shaw R. J., Cantley L. C., Nature (London), 441, 424-430 (2006).
4. Linggi B., Carpenter G., Trends Cell Biol., 16, 649-656 (2006).
5. Stauffer F., Holzer P., Garcia-Echeverria C., Curr. Med. Chem. Anticancer Agents, 5, 449-462 (2005).
6. Osaki M., Oshimura M., Ito H., Apoptosis, 9, 667-676 (2004).
7. Vivanco I., Sawyers C. L., Nat. Rev. Cancer, 2, 489-501 (2002).
8. Fresno Vara J. A., Casado E., de Castro J., Cejas P., Belda-Iniesta C., Gonzalez-Baron M., Cancer Treat. Rev., 30, 193-204 (2004).
9. Dancey J. E., Cancer Biol. Ther., 5, 1065-1073 (2006).
10. Cully M., You H., Levine A. J., Mak T. W., Nat. Rev. Cancer, 6, 184-192 (2006).
11. Leslie N. R., Downes C. P., Biochem. J., 382, 1-11 (2004).
12. Kim R. H., Mak T. W., Br. J. Cancer, 94, 620-624 (2006).
13. Karakas B., Bachman K. E., Park B. H., Br. J. Cancer, 94, 455-459 (2006).
14. Samuels Y., Diaz L. A., Jr., Schmidt-Kittler O., Cummins J. M., Delong L., Cheong I., Rago C., Huso D. L., Lengauer C., Kinzler K. W., Vogelstein B., Velculescu V. E., Cancer Cell, 7, 561-573 (2005).
15. Samuels Y., Wang Z., Bardelli A., Silliman N., Ptak J., Szabo S., Yan H., Gazdar A., Powell S. M., Riggins G. J., Willson J. K., Markowitz S., Kinzler K. W., Vogelstein B., Velculescu V. E., Science, 304, 554 (2004).
16. Dos Santos C., Recher C., Demur C., Payrastre B., Bull. Cancer, 93, 445-447 (2006).
17. Stephens L., Williams R., Hawkins P., Curr. Opin. Pharmacol., 5, 357-365 (2005).
18. Cortot A., Armand J. P., Soria J. C., Bull. Cancer, 93, 19-26 (2006).
19. Wymann M. P., Marone R., Curr. Opin. Cell Biol., 17, 141-149 (2005).
20. Bader A. G., Kang S., Zhao L., Vogt P. K., Nat. Rev. Cancer, 5, 921-929 (2005).
21. Anderson K. E., Jackson S. P., Int. J. Biochem. Cell Biol., 35, 1028-1033 (2003).
22. Vanhaesebroeck B., Welham M. J., Kotani K., Stein R., Warne P. H., Zvelebil M. J., Higashi K., Volinia S., Downward J., Waterfield M. D., Proc. Natl. Acad. Sci. U.S.A., 94, 4330-4335 (1997).
23. Hu P., Mondino A., Skolnik E. Y., Schlessinger J., Mol. Cell Biol., 13, 7677-7688 (1993).
24. Bi L., Okabe I., Bernard D. J., Wynshaw-Boris A., Nussbaum R. L., J. Biol. Chem., 274, 10963-10968 (1999).
25. Chantry D., Vojtek A., Kashishian A., Holtzman D. A., Wood C., Gray P. W., Cooper J. A., Hoekstra M. F., J. Biol. Chem., 272, 19236-19241 (1997).
26. Ruckle T., Schwarz M. K., Rommel C., Nat. Rev. Drug Discov., 5, 903-918 (2006).
27. Rommel C., Camps M., Ji H., Nat. Rev. Immunol., 7, 191-201 (2007).
28. Zhao J. J., Cheng H., Jia S., Wang L., Gjoerup O. V., Mikami A., Roberts T. M., Proc. Natl. Acad. Sci. U.S.A., 103, 16296-16300 (2006).
29. Knight Z. A., Gonzalez B., Feldman M. E., Zunder E. R., Goldenberg D. D., Williams O., Loewith R., Stokoe D., Balla A., Toth B., Balla T., Weiss W. A., Williams R. L., Shokat K. M., Cell, 125, 733-747 (2006).
30. Jackson S. P., Schoenwaelder S. M., Goncalves I., Nesbitt W. S., Yap C. L., Wright C. E., Kenche V., Anderson K. E., Dopheide S. M., Yuan Y., Sturgeon S. A., Prabaharan H., Thompson P. E., Smith G. D., Shepherd P. R., Daniele N., Kulkarni S., Abbott B., Saylik D., Jones C., Lu L., Giuliano S., Hughan S. C., Angus J. A., Robertson A. D., Salem H. H., Nat. Med., 11, 507-514 (2005).
31. Okkenhaug K., Bilancio A., Farjot G., Priddle H., Sancho S., Peskett E., Pearce W., Meek S. E., Salpekar A., Waterfield M. D., Smith A. J., Vanhaesebroeck B., Science, 297, 1031-1034 (2002).
32. Sasaki T., Irie-Sasaki J., Jones R. G., Oliveira-dos-Santos A. J., Stanford W. L., Bolon B., Wakeham A., Itie A., Bouchard D., Kozieradzki I., Joza N., Mak T. W., Ohashi P. S., Suzuki A., Penninger J. M., Science, 287, 1040-1046 (2000).
33. Hirsch E., Katanaev V. L., Garlanda C., Azzolino O., Pirola L., Silengo L., Sozzani S., Mantovani A., Altruda F., Wymann M. P., Science, 287, 1049-1053 (2000).
34. Shayesteh L., Lu Y., Kuo W. L., Baldocchi R., Godfrey T., Collins C., Pinkel D., Powell B., Mills G. B., Gray J. W., Nat. Genet., 21, 99-102 (1999).
35. Ma Y. Y., Wei S. J., Lin Y. C., Lung J. C., Chang T. C., Whang-Peng J., Liu J. M., Yang D. M., Yang W. K., Shen C. Y., Oncogene, 19, 2739-2744 (2000).
36. Campbell I. G., Russell S. E., Choong D. Y., Montgomery K. G., Ciavarella M. L., Hooi C. S., Cristiano B. E., Pearson R. B., Phillips W. A., Cancer Res., 64, 7678-7681 (2004).
37. Redon R., Muller D., Caulee K., Wanherdrick K., Abecassis J., du Manoir S., Cancer Res., 61, 4122-4129 (2001).
38. Lee J. W., Soung Y. H., Kim S. Y., Lee H. W., Park W. S., Nam S. W., Kim S. H., Lee J. Y., Yoo N. J., Lee S. H., Oncogene, 24, 1477-1480 (2005).
39. Saal L. H., Holm K., Maurer M., Memeo L., Su T., Wang X., Yu J. S., Malmstrom P. O., Mansukhani M., Enoksson J., Hibshoosh H., Borg A., Parsons R., Cancer Res., 65, 2554-2559 (2005).
40. Levine D. A., Bogomolniy F., Yee C. J., Lash A., Barakat R. R., Borgen P. I., Boyd J., Clin. Cancer Res., 11, 2875-2878 (2005).
41. Phillips W. A., Russell S. E., Ciavarella M. L., Choong D. Y., Montgomery K. G., Smith K., Pearson R. B., Thomas R. J., Campbell I. G., Int. J. Cancer, 118, 2644-2646 (2006).
42. Dan S., Tsunoda T., Kitahara O., Yanagawa R., Zembutsu H., Katagiri T., Yamazaki K., Nakamura Y., Yamori T., Cancer Res., 62, 1139-1147 (2002).
43. Yamori T., Matsunaga A., Sato S., Yamazaki K., Komi A., Ishizu K., Mita I., Edatsugi H., Matsuba Y., Takezawa K., Nakanishi O., Kohno H., Nakajima Y., Komatsu H., Andoh T., Tsuruo T., Cancer Res., 59, 4042-4049 (1999).
44. Yaguchi S., Fukui Y., Koshimizu I., Yoshimi H., Matsuno T., Gouda H., Hirono S., Yamazaki K., Yamori T., J. Natl. Cancer Inst., 98, 545-556 (2006).