Telomere dysfunction and inactivation of the p16INK4a/Rb pathway in pyothorax-associated lymphoma

Cancer Science

Volumn 98, Issue 7, 2007, Pages 978-984

  Tresnasari, Kristianti ^a   Takakuwa, Tetsuya ^a   Ham, Maria Francisca ^a   Rahadiani, Nur ^a   Nakajima, Hiroo ^a   Aozasa, Katsuyuki ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P16INK4A; RETINOBLASTOMA PROTEIN; TELOMERASE;

ADULT; ARTICLE; BURKITT LYMPHOMA; CARCINOGENESIS; CELL DIVISION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA METHYLATION; ENZYME ACTIVITY; FEMALE; GENE INACTIVATION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; LEUKOCYTE; LYMPHOMA; LYMPHOMA CELL LINE; MALE; MALIGNANT TRANSFORMATION; NUCLEOTIDE SEQUENCE; PLEURA EMPYEMA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TELOMERE;

CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA, NEOPLASM; HUMANS; LYMPHOMA; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RETINOBLASTOMA PROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, NEOPLASM; TELOMERASE; TELOMERE; THORACIC NEOPLASMS;

EID: 34249909815     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2007.00482.x     Document Type: Article

References (40)

1. Nakatsuka S, Yao M, Hoshida Y, Yamamoto S, Iuchi K, Aozasa K. Pyothorax-associated lymphoma: A review of 106 cases. J Clin Oncol 2003; 20: 4255-60.
2. Iuchi K, Aozasa K, Yamamoto S et al. Non-Hodgkin's lymphoma of the pleural cavity developing from long-standing pyothorax. Summary of clinical and pathological findings in thirty-seven cases. Jpn J Clin Oncol 1989; 19: 249-57.
3. Banks PM, Harris NL, Warnke RA, Gaulard Ph. Lymphomas. In: Travis WD, Brambilla E, Mueller-Hermelink HK, Harris CC, eds. World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of the Lung, Pleura, Thymus and Heart. Lyon: IARC Press, 2004: 137-40.
4. Kanno H, Yasunaga Y, Ohsawa M et al. Expression of Epstein-Barr virus latent infection genes and oncogenes in lymphoma cell lines derived from pyothorax-associated lymphoma. Int J Cancer 1996; 67: 86-94.
5. Takakuwa T, Luo WJ, Ham MF, Mizuki M, Iuchi K, Aozasa K. Establishment and characterization of unique cell lines derived from pyothorax-associated lymphoma which develops in long-standing pyothorax and is strongly associated with Epstein-Barr virus infection. Cancer Sci 2003; 94: 858-63.
6. Blackburn EH. Switching and signaling at the telomere. Cell 2001; 106: 661-73.
7. Moyzis RK, Buckingham JM, Cram LS et al. A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes. Proc Natl Acad Sci USA 1988; 85: 6622-6.
8. Artandi SE, DePinho RA. A critical role for telomeres in suppressing and facilitating carcinogenesis. Curr Opin Genet Dev 2000; 10: 39-46.
9. Ohtani N, Yamakoshi K, Takahashi A, Hara E. The p16 INK4a -RB pathway: molecular link between cellular senescence and tumor suppression. J Med Invest 2004; 51: 146-53.
10. Meeker AK, Hicks JL, Platz EA et al. Telomere shortening is an early somatic DNA alteration in human prostate tumorigenesis. Cancer Res 2002; 62: 6405-9.
11. Zhang A, Wang J, Zheng B et al. Telomere attrition predominantly occurs in precursor lesions during in vivo carcinogenic process of the uterine cervix. Oncogene 2004; 23: 7441-7.
12. Gisselsson D, Jonson T, Petersen A et al. Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors. Proc Natl Acad Sci USA 2001; 98: 12.683-8.
13. Chadeneau C, Hay K, Hirte HW, Gallinger S, Bacchetti S. Telomerase activity associated with acquisition of malignancy in human colorectal cancer. Cancer Res 1995; 55: 2533-6.
14. al Saati T, Delecluze HJ, Chittal S et al. A novel human lymphoma cell line (Deglis) with dual B/T phenotype and gene rearrangements and containing Epstein-Barr virus genomes. Blood 1992; 80: 209-16.
15. Daibata M, Taguchi T, Nemoto Y et al. Epstein-Barr virus (EBV)-positive pyothorax-associated lymphoma (PAL): Chromosome integration of EBV in a novel CD2-positive PAL B-cell line. Br J Haematol 2002; 117: 546-57.
16. King W, Thomas PA, Raab TN, Hawke M, Kieff E. Epstein-Barr virus RNA. V. Viral RNA in a restringently infected, growth-transformed cell line. J Virol 1980; 36: 506-18.
17. van den Berg A, Kroesen BJ, Kooistra K et al. High expression of B-cell receptor inducible gene BIC in all subtypes of Hodgkin lymphoma. Genes Chromosomes Cancer 2003; 37: 20-8.
18. Perner S, Bruderlein S, Hasel C et al. Quantifying telomere lengths of human individual chromosome arms by centromere-calibrated fluorescence in situ hybridization and digital imaging. Am J Pathol 2003; 163: 1751-6.
19. Hongyo T, Kurooka M, Taniguchi E et al. Frequent p53 mutations at dipyrimidine sites in patients with pyothorax-associated lymphoma. Cancer Res 1998; 58: 1105-7.
20. Sato M, Horio Y, Sekido Y, Minna JD, Shimokata K, Hasegawa Y. The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14 ARF, p16 INK4A and RASSF1A in human lung cancer cell lines. Oncogene 2002; 21: 4822-9.
21. Sakuma K, Chong JM, Sudo M et al. High-density methylation of p14 ARF and p16 INK4A in Epstein-Barr virus-associated gastric carcinoma. Int J Cancer 2004; 112: 273-8.
22. Meyerson M, Counter CM, Eaton EN et al. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell 1997; 90: 785-95.
23. Nakamura TM, Morin GB, Chapman KB et al. Telomerase catalytic subunit homologs from fission yeast and human. Science 1997; 277: 955-9.
24. Ohyashiki JH, Sashida G, Tauchi T, Ohyashiki K. Telomeres and telomerase in hematologic neoplasia. Oncogene 2002; 21: 680-7.
25. Harada K, Kurisu K, Arita K et al. Telomerase activity in central nervous system malignant lymphoma. Cancer 1999; 86: 1050-5.
26. Remes K, Norrback KF, Rosenquist R, Mehle C, Lindh J, Roos G. Telomere length and telomerase activity in malignant lymphomas at diagnosis and relapse. Br J Cancer 2000; 82: 601-7.
27. O'Sullivan JN, Bronner MP, Brentnall TA et al. Chromosomal instability in ulcerative colitis is related to telomere shortening. Nat Genet 2002; 32: 280-4.
28. Kiyono T, Foster SA, Koop JI, McDougall JK, Galloway DA, Klingelhutz AJ. Both Rb/p16 INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature 1998; 396: 84-8.
29. Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16 INK4a. Cell 1997; 88: 593-602.
30. Braig M, Lee S, Loddenkemper C et al. Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 2005; 436: 660-5.
31. Michaloglou C, Vredeveld LC, Soengas MS et al. BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature 2005; 436: 720-4.
32. Moller MB, Kania PW, Ino Y et al. Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma: Prognostic significance of E2F-1 and p16 INK4A. Leukemia 2000; 14: 898-904.
33. Counter CM. The roles of telomeres and telomerase in cell life span. Mutat Res 1996; 366: 45-63.
34. Lundblad V, Szostak JW. A mutant with a defect in telomere elongation leads to senescence in yeast. Cell 1989; 57: 633-43.
35. Blasco MA, Lee HW, Hande MP et al. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 1997; 91: 25-34.
36. Hastie ND, Allshire RC. Human telomeres: Fusion and interstitial sites. Trends Genet 1989; 5: 326-31.
37. Klapper W, Krams M, Qian W, Janssen D, Parwaresch R. Telomerase activity in B-cell non-Hodgkin lymphomas is regulated by hTERT transcription and correlated with telomere-binding protein expression but uncoupled from proliferation. Br J Cancer 2003; 89: 713-19.
38. Slijepcevic P. The role of DNA damage response proteins at telomeres-an 'integrative'model. DNA Repair 2006; 22: 1299-306.
39. Metcalfe JA, Parkhill J, Campbell L et al. Accelerated telomere shortening in ataxia telangiectasia. Nat Genet 1996; 13: 350-3.
40. Liu A, Takakuwa T, Fujita S et al. Alterations of DNA damage-response genes ATM and ATR in pyothorax-associated lymphoma. Lab Invest 2005; 85: 436-46.