Characterization of a gene cluster responsible for the biosynthesis of anticancer agent FK228 in Chromobacterium violaceum No. 968

Applied and Environmental Microbiology

Volumn 73, Issue 11, 2007, Pages 3460-3469

  Cheng, Yi Qiang ^a   Yang, Min ^a   Matter, Andrea M ^a  

^a UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOSYNTHESIS; DNA; NUCLEOTIDES; PEPTIDES; TUMORS;

ANTICANCER AGENTS; CHROMOBACTERIUM VIOLACEUM; GENE CLUSTERS; GENETIC SYSTEMS;

GENETIC ENGINEERING;

ANTINEOPLASTIC AGENT; CYSTEINE; DISULFIDE; FLAVINE ADENINE NUCLEOTIDE; FR 901228; NATURAL PRODUCT; OXIDOREDUCTASE; PEPTIDE SYNTHASE; POLYKETIDE SYNTHASE; THIOL DERIVATIVE;

BACTERIUM; CATALYSIS; CLONE; DNA; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC ENGINEERING; GENOMICS;

ARTICLE; BACTERIUM MUTANT; CHROMOBACTERIUM VIOLACEUM; CONTROLLED STUDY; DISULFIDE BOND; DRUG STRUCTURE; DRUG SYNTHESIS; GENE CLUSTER; GENE SEQUENCE; GENETIC CODE; GENETIC ENGINEERING; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PSEUDOMONAS AERUGINOSA; SEQUENCE ANALYSIS; STRAIN DIFFERENCE;

CHROMOBACTERIUM; CLONING, MOLECULAR; DEPSIPEPTIDES; DISULFIDES; DNA, BACTERIAL; GENE DELETION; GENES, BACTERIAL; METABOLIC NETWORKS AND PATHWAYS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MULTIGENE FAMILY; OXIDATION-REDUCTION; OXIDOREDUCTASES; PEPTIDE SYNTHASES; POLYKETIDE SYNTHASES; SEQUENCE ANALYSIS, DNA;

CHROMOBACTERIUM VIOLACEUM; PSEUDOMONAS AERUGINOSA;

EID: 34249895594     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/AEM.01751-06     Document Type: Article

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