Characterization of the cereulide NRPS α-hydroxy acid specifying modules: Activation of α-keto acids and chiral reduction on the assembly line

Journal of the American Chemical Society

Volumn 128, Issue 33, 2006, Pages 10698-10699

  Magarvey, Nathan A ^a   Ehling Schulz, Monika ^b   Walsh, Christopher T ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYACID; ADENOSINE TRIPHOSPHATE; ALPHA AMINO ACID; CARBON 14; CEREULIDE; DEPSIPEPTIDE; DNA FRAGMENT; GENOMIC DNA; ISOLEUCINE; MACROCYCLIC COMPOUND; NATURAL PRODUCT; UNCLASSIFIED DRUG; VALINE; VALINOMYCIN;

ARTICLE; BACILLUS CEREUS; BIOSYNTHESIS; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHIRALITY; ENZYME ACTIVITY; GENE CLUSTER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; NONHUMAN; STREPTOMYCES;

DEPSIPEPTIDES; KETO ACIDS; MOLECULAR STRUCTURE; PEPTIDE SYNTHASES; VALINOMYCIN;

EID: 33747799012     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0640187     Document Type: Article

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