Cre-conditional expression of constitutively active Notch1 in transgenic mice

Genesis (United States)

Volumn 45, Issue 5, 2007, Pages 259-265

  Liu, Ju ^a,b   Lobe, Corrinne G ^a,b  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Angiogenesis; Cre loxP; Neural tube; Notch; Somitogenesis

Indexed keywords

ALKALINE PHOSPHATASE PLACENTA ISOENZYME; BETA GALACTOSIDASE; CRE RECOMBINASE; GREEN FLUORESCENT PROTEIN; NOTCH1 RECEPTOR;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL LINE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DEVELOPMENTAL DISORDER; EMBRYO; EMBRYO DEVELOPMENT; FLOXED GENE; GENE SEQUENCE; GROWTH DISORDER; HISTOLOGY; MORPHOLOGY; MOUSE; NEURAL TUBE; NEURAL TUBE DEFECT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOMITE; TRANSGENE; TRANSGENIC MOUSE;

MAMMALIA; MUS; MUS MUSCULUS;

EID: 34249679150     PISSN: 1526954X     EISSN: 1526968X     Source Type: Journal    
DOI: 10.1002/dvg.20282     Document Type: Article

References (40)

1. Alva JA, Iruela-Arispe ML. 2004. Notch signaling in vascular morphogenesis. Curr Opin Hematol 11:278-283.
2. Beatus P, Lendahl U. 1998. Notch and neurogenesis. J Neurosci Res 54:125-136.
3. Bellavia D, Campese AF, Alesse E, Vacca A, Felli MP, Balestri A, Stoppacciaro A, Tiveron C, Tatangelo L, Giovarelli M, Gaetano C, Ruco L, Hoffman ES, Hayday AC, Lendahl U, Frati L, Gulino A, Screpanti I. 2000. Constitutive activation of NF-κB and T-cell leukemia/lymphoma in Notch3 transgenic mice. Embo J 19:3337-3348.
4. Belteki G, Haigh J, Kabacs N, Haigh K, Sison K, Costantini F, Whitsett J, Quaggin SE, Nagy A. 2005. Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction. Nucleic Acids Res 33:e51.
5. Conlon RA, Reaume AG, Rossant J. 1995. Notch1 is required for the coordinate segmentation of somites. Development 121:1533-1545.
6. Duarte A, Hirashima M, Benedito R, Trindade A, Diniz P, Bekman E, Costa L, Henrique D, Rossant J. 2004. Dosage-sensitive requirement for mouse D114 in artery development. Genes Dev 18:2474-2478.
7. Ellisen LW, Bird J, West DC, Soreng AL, Reynolds TC, Smith SD, Sklar J. 1991. TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66:649-661.
8. Galceran J, Sustmann C, Hsu SC, Folberth S, Grosschedl R. 2004. LEF1-mediated regulation of Delta-like 1 links Wnt and Notch signaling in somitogenesis. Genes Dev 18:2718-2723.
9. Gallahan D, Jhappan C, Robinson G, Hennighausen L, Sharp R, Kordon E, Callahan R, Merlino G, Smith GH. 1996. Expression of a truncated 1nt3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis. Cancer Res 56:1775-1785.
10. Garcia EL, Mills AA. 2002. Getting around lethality with inducible Cre-mediated excision. Semin Cell Dev Biol 13:151-158.
11. Gridley T. 1997. Notch signaling in vertebrate development. Mol Cell Neuroscience 9:103-108.
12. Hamada Y, Kadokawa Y, Okabe M, Ikawa M, Coleman JR, Tsujimoto Y. 1999. Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality. Development 126:3415-3424.
13. Hebert JM, McConnell SK. 2000. Targeting of cre to the foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures. Dev Biol 222:296-306.
14. Hitoshi S, Alexson T, Tropepe V, Donoviel D, Elia AJ, Nye JS, Conlon RA, Mak TW, Bernstein A, van der Kooy D. 2002. Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells. Genes Dev 16:846-858.
15. Iso T, Chung G, Hamamori Y, Kedes L. 2002. HERP1 is a cell type-specific primary target of Notch. J Biol Chem 277:6598-6607.
16. Joutel A, Corpechot C, Ducros A, Vahedi K, Chabriat H, Mouten P, Alamowitch S, Domenga V, Cecillion M, Vayssiere C, Cruaud C, Cabanis E-A, Ruchoux M, Weissenbach J, Bach J, Bousser M, Tournier-Lasserve E. 1996. Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia. Nature 383:707-710.
17. Kiefer JC. 2005. The somite segmentation clock: It takes a licking and keeps on ticking. Dev Dyn 232:519-523.
18. Krebs LT, Xue Y, Norton CR, Shutter JR, Maguire M, Sundberg JP, Callahan D, Closson V, Kitajewski J, Callahan R, Smith GH, Stark KL, Gridley T. 2000. Notch signaling is essential for vascular morphogenesis in mice. Genes Dev 14:1343-1352.
19. Krebs LT, Xue Y, Norton CR, Sundberg JP, Beatus P, Lendahl U, Joutel A, Gridley T. 2003. Characterization of Notch3-deficient mice: Normal embryonic development and absence of genetic interactions with a Notch1 mutation. Genesis 37:139-143.
20. Lefort K, Dotto GR 2004. Notch signaling in the integrated control of keratinocyte growth/differentiation and tumor suppression. Semin Cancer Biol 14:374-386.
21. Lewandoski M, Martin GR. 1997. Cre-mediated chromosome loss in mice. Nat Genet 17:223-225.
22. Lewis J. 1998. Notch signalling and the control of cell fate choices in vertebrates. Semin Cell Dev Biol 9:583-589.
23. Lobe CG, Koop KE, Kreppner W, Lomeli H, Gertsenstein M, Nagy A. 1999. Z/AP, a double reporter for cre-mediated recombination. Dev Biol 208:281-292.
24. Mereau A, Grey L, Piquet-Pellorce C, Heath JK. 1993. Characterization of a binding protein for leukemia inhibitory factor localized in extracellular matrix. J Cell Biol 122:713-719.
25. Murtaugh LC, Stanger BZ, Kwan KM, Melton DA. 2003. Notch signaling controls multiple steps of pancreatic differentiation. Proc Natl Acad Sci USA 100:14920-14925.
26. Nagy A, Rossant J. 1993. Production of completely ES cell-derived fetuses. In: Joyner A, editor. Gene Targeting: A Practical Approach. Oxford: IRL Press, pp 147-179.
27. Nagy A, Rossant J, Nagy R, Abramow-Newerly W, Roder J. 1993. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci USA 90:8424-8428.
28. Novak A, Guo C, Yang W, Nagy A, Lobe CG. 2000. Z/EG, a double reporter transgenic mouse line that expresses enhanced green fluorescent protein upon Cre-mediated recombination. Genesis 28:147-155.
29. Pahlman S, Stockhausen MT, Fredlund E, Axelson H. 2004. Notch signaling in neuroblastoma. Semin Cancer Biol 14:365-373.
30. Pear WS, Aster JC. 2004. T cell acute lymphoblastic leukemia/lymphoma: A human cancer commonly associated with aberrant NOTCH1 signaling. Curr Opin Hematol 11:426-433.
31. Pear WS, Radtke F. 2003. Notch signaling in lymphopoiesis. Semin Immunol 15:69-79.
32. Politi K, Feirt N, Kitajewski J. 2004. Notch in mammary gland development and breast cancer. Semin Cancer Biol 14:341-347.
33. Radtke F, Wilson A, Mancini SJ, MacDonald HR. 2004. Notch regulation of lymphocyte development and function. Nat Immunol 5:247-253.
34. Shawber C, Nofziger D, Hsieh JJ-D, Lindsell C, Bogler O, Hayward D, Weinmaster G. 1996. Notch signaling inhibts muscle cell differentiation through CBF1-independent pathway. Development 122:3765-3773.
35. Swiatek PJ, Lindsell CE, Franco del Amo F, Weinmaster G, Gridley T. 1994. Notch1 is essential for postimplantation development in mice. Genes Dev 8:707-719.
36. Tomita S, Sinai CJ, Yim SH, Gonzalez FJ. 2000. Conditional disruption of the aryl hydrocarbon receptor nuclear translocator (Arnt) gene leads to loss of target gene induction by the aryl hydrocarbon receptor and hypoxia-inducible factor 1α. Mol Endocrinol 14:1674-1681.
37. Uyttendaele H, Ho J, Rossant J, Kitajewski J. 2001. Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium. Proc Natl Acad Sci USA 98:5643-5648.
38. Watanabe Y, Kokubo H, Miyagawa-Tomita S, Endo M, Igarashi K, Aisaki K, Kanno J, Saga Y. 2006. Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse. Development 133:1625-1634.
39. Xue Y, Gao X, Lindsell CE, Norton CR, Chang B, Hicks C, Gendron-Maguire M, Rand EB, Wcinmaster G, Gridley T. 1999. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged 1. Hum Mol Genet 8:723-730.
40. Yang X, Klein R, Tian X, Cheng HT, Kopan R, Shen J. 2004. Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway. Dev Biol 269:81-94.