메뉴 건너뛰기




Volumn 153, Issue 6, 2007, Pages 891-899

Current concepts in the mechanisms and management of drug-induced QT prolongation and torsade de pointes

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; ANTIARRHYTHMIC AGENT; AZITHROMYCIN; BUTYROPHENONE; CHLOROQUINE; CHLORPROMAZINE; CISAPRIDE; CLARITHROMYCIN; DISOPYRAMIDE; DOFETILIDE; DROPERIDOL; ERYTHROMYCIN; FLUCONAZOLE; HALOFANTRINE; IBUTILIDE; ITRACONAZOLE; KETOCONAZOLE; MACROLIDE; MAGNESIUM SULFATE; MESORIDAZINE; PENTAMIDINE; PHENOTHIAZINE; PROCAINAMIDE; QUINIDINE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SOTALOL; SPARFLOXACIN; THIORIDAZINE; UNINDEXED DRUG; VORICONAZOLE;

EID: 34249330240     PISSN: 00028703     EISSN: 10976744     Source Type: Journal    
DOI: 10.1016/j.ahj.2007.01.040     Document Type: Review
Times cited : (313)

References (97)
  • 1
    • 0002304545 scopus 로고
    • Quinidine syncope. Paroxysmal ventricular fibrillation occurring during treatment of chronic atrial arrhythmias
    • Selzer A., and Wray H.W. Quinidine syncope. Paroxysmal ventricular fibrillation occurring during treatment of chronic atrial arrhythmias. Circulation 30 (1964) 17-26
    • (1964) Circulation , vol.30 , pp. 17-26
    • Selzer, A.1    Wray, H.W.2
  • 2
    • 0013881809 scopus 로고
    • Ventricular tachycardia with 2 variable opposing foci
    • Dessertenne F. Ventricular tachycardia with 2 variable opposing foci. Arch Mal Coeur Vaiss 59 (1966) 263-272
    • (1966) Arch Mal Coeur Vaiss , vol.59 , pp. 263-272
    • Dessertenne, F.1
  • 3
    • 0036570099 scopus 로고    scopus 로고
    • Timing of new black box warnings and withdrawals for prescription medications
    • Lasser K.E., Allen P.D., Woolhandler S.J., et al. Timing of new black box warnings and withdrawals for prescription medications. JAMA 287 (2002) 2215-2220
    • (2002) JAMA , vol.287 , pp. 2215-2220
    • Lasser, K.E.1    Allen, P.D.2    Woolhandler, S.J.3
  • 4
    • 33645467146 scopus 로고    scopus 로고
    • An evaluation of ECG leads used to assess QT prolongation
    • Sadanaga T., Sadanaga F., Yao H., et al. An evaluation of ECG leads used to assess QT prolongation. Cardiology 105 (2006) 149-154
    • (2006) Cardiology , vol.105 , pp. 149-154
    • Sadanaga, T.1    Sadanaga, F.2    Yao, H.3
  • 5
    • 0025825919 scopus 로고
    • Variability of the QT measurement in healthy men, with implications for selection of an abnormal QT value to predict drug toxicity and proarrhythmia
    • Morganroth J., Brozovich F.V., McDonald J.T., et al. Variability of the QT measurement in healthy men, with implications for selection of an abnormal QT value to predict drug toxicity and proarrhythmia. Am J Cardiol 67 (1991) 774-776
    • (1991) Am J Cardiol , vol.67 , pp. 774-776
    • Morganroth, J.1    Brozovich, F.V.2    McDonald, J.T.3
  • 6
    • 0030058329 scopus 로고    scopus 로고
    • Diurnal pattern of QTc interval: how long is prolonged? Possible relation to circadian triggers of cardiovascular events
    • Molnar J., Zhang F., Weiss J., et al. Diurnal pattern of QTc interval: how long is prolonged? Possible relation to circadian triggers of cardiovascular events. J Am Coll Cardiol 27 (1996) 76-83
    • (1996) J Am Coll Cardiol , vol.27 , pp. 76-83
    • Molnar, J.1    Zhang, F.2    Weiss, J.3
  • 7
    • 17144455548 scopus 로고    scopus 로고
    • Electrocardiographic findings in a healthy biracial population. Atherosclerosis Risk in Communities (ARIC) Study Investigators
    • Vitelli L.L., Crow R.S., Shahar E., et al. Electrocardiographic findings in a healthy biracial population. Atherosclerosis Risk in Communities (ARIC) Study Investigators. Am J Cardiol 81 (1998) 453-459
    • (1998) Am J Cardiol , vol.81 , pp. 453-459
    • Vitelli, L.L.1    Crow, R.S.2    Shahar, E.3
  • 8
    • 0034662769 scopus 로고    scopus 로고
    • Comparison of QT intervals in African-Americans versus Caucasians
    • Sgarbossa E.B., Pinski S.L., Williams D., et al. Comparison of QT intervals in African-Americans versus Caucasians. Am J Cardiol 86 (2000) 880-882
    • (2000) Am J Cardiol , vol.86 , pp. 880-882
    • Sgarbossa, E.B.1    Pinski, S.L.2    Williams, D.3
  • 9
    • 0001127258 scopus 로고
    • An analysis of the time-relations of the electrocardiogram
    • Bazett H.C. An analysis of the time-relations of the electrocardiogram. Heart 7 (1920) 353-362
    • (1920) Heart , vol.7 , pp. 353-362
    • Bazett, H.C.1
  • 10
    • 33747864799 scopus 로고    scopus 로고
    • Bazett and Fridericia QT correction formulas interfere with measurement of drug-induced changes in QT interval
    • Indik J.H., Pearson E.C., Fried K., et al. Bazett and Fridericia QT correction formulas interfere with measurement of drug-induced changes in QT interval. Heart Rhythm 3 (2006) 1003-1007
    • (2006) Heart Rhythm , vol.3 , pp. 1003-1007
    • Indik, J.H.1    Pearson, E.C.2    Fried, K.3
  • 12
    • 0242494266 scopus 로고    scopus 로고
    • What clinicians should know about the QT interval
    • Al-Khatib S.M., LaPointe N.M., and Kramer J.M. What clinicians should know about the QT interval. JAMA 289 (2003) 2120-2127
    • (2003) JAMA , vol.289 , pp. 2120-2127
    • Al-Khatib, S.M.1    LaPointe, N.M.2    Kramer, J.M.3
  • 13
    • 0026719864 scopus 로고
    • Reduction of QT-interval imprecision and variance by measuring the JT interval
    • Spodick D.H. Reduction of QT-interval imprecision and variance by measuring the JT interval. Am J Cardiol 70 (1992) 103
    • (1992) Am J Cardiol , vol.70 , pp. 103
    • Spodick, D.H.1
  • 14
    • 0030901512 scopus 로고    scopus 로고
    • Effects of the ventricular activation sequence on the JT interval
    • Banker J., Dizon J., and Reiffel J. Effects of the ventricular activation sequence on the JT interval. Am J Cardiol 79 (1997) 816-819
    • (1997) Am J Cardiol , vol.79 , pp. 816-819
    • Banker, J.1    Dizon, J.2    Reiffel, J.3
  • 15
    • 0036847942 scopus 로고    scopus 로고
    • Cardiac repolarization: current knowledge, critical gaps, and new approaches to drug development and patient management
    • Anderson M.E., Al-Khatib S.M., Roden D.M., et al. Cardiac repolarization: current knowledge, critical gaps, and new approaches to drug development and patient management. Am Heart J 144 (2002) 769-781
    • (2002) Am Heart J , vol.144 , pp. 769-781
    • Anderson, M.E.1    Al-Khatib, S.M.2    Roden, D.M.3
  • 16
    • 0034710933 scopus 로고    scopus 로고
    • A structural basis for drug-induced long QT syndrome
    • Mitcheson J.S., Chen J., Lin M., et al. A structural basis for drug-induced long QT syndrome. Proc Natl Acad Sci U S A 97 (2000) 12329-12333
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 12329-12333
    • Mitcheson, J.S.1    Chen, J.2    Lin, M.3
  • 17
    • 16244414305 scopus 로고    scopus 로고
    • Anti-HERG activity and the risk of drug-induced arrhythmias and sudden death
    • De Bruin M.L., Pettersson M., Meyboom R.H., et al. Anti-HERG activity and the risk of drug-induced arrhythmias and sudden death. Eur Heart J 26 (2005) 590-597
    • (2005) Eur Heart J , vol.26 , pp. 590-597
    • De Bruin, M.L.1    Pettersson, M.2    Meyboom, R.H.3
  • 18
    • 0029847602 scopus 로고    scopus 로고
    • Multiple mechanisms in the long-QT syndrome. Current knowledge, gaps, and future directions. The SADS Foundation Task Force on LQTS
    • Roden D.M., Lazzara R., Rosen M., et al. Multiple mechanisms in the long-QT syndrome. Current knowledge, gaps, and future directions. The SADS Foundation Task Force on LQTS. Circulation 94 (1996) 1996-2012
    • (1996) Circulation , vol.94 , pp. 1996-2012
    • Roden, D.M.1    Lazzara, R.2    Rosen, M.3
  • 20
    • 27744493604 scopus 로고    scopus 로고
    • Role or transmural dispersion of repolarization in the genesis of drug-induced torsades de pointes
    • Antzelevitch C. Role or transmural dispersion of repolarization in the genesis of drug-induced torsades de pointes. Heart Rhythm 2 (2005) S9-S15
    • (2005) Heart Rhythm , vol.2
    • Antzelevitch, C.1
  • 21
    • 0033608876 scopus 로고    scopus 로고
    • Drug-induced torsade de pointes
    • Trohman R.G., and Sahu J. Drug-induced torsade de pointes. Circulation 99 (1999) E7
    • (1999) Circulation , vol.99
    • Trohman, R.G.1    Sahu, J.2
  • 22
    • 0142209158 scopus 로고    scopus 로고
    • Drug induced QT prolongation and torsades de pointes
    • Yap Y.G., and Camm A.J. Drug induced QT prolongation and torsades de pointes. Heart 89 (2003) 1363-1372
    • (2003) Heart , vol.89 , pp. 1363-1372
    • Yap, Y.G.1    Camm, A.J.2
  • 24
    • 0026466153 scopus 로고
    • Precordial QT interval dispersion as a marker of torsade de pointes. Disparate effects of class Ia antiarrhythmic drugs and amiodarone
    • Hii J.T., Wyse D.G., Gillis A.M., et al. Precordial QT interval dispersion as a marker of torsade de pointes. Disparate effects of class Ia antiarrhythmic drugs and amiodarone. Circulation 86 (1992) 1376-1382
    • (1992) Circulation , vol.86 , pp. 1376-1382
    • Hii, J.T.1    Wyse, D.G.2    Gillis, A.M.3
  • 25
    • 12344307070 scopus 로고    scopus 로고
    • Drug-induced QT dispersion: does it predict the risk of torsade de pointes?
    • Shah R.R. Drug-induced QT dispersion: does it predict the risk of torsade de pointes?. J Electrocardiol 38 (2005) 10-18
    • (2005) J Electrocardiol , vol.38 , pp. 10-18
    • Shah, R.R.1
  • 26
    • 0028069574 scopus 로고
    • Electrical alternans and vulnerability to ventricular arrhythmias
    • Rosenbaum D.S., Jackson L.E., Smith J.M., et al. Electrical alternans and vulnerability to ventricular arrhythmias. N Engl J Med 330 (1994) 235-241
    • (1994) N Engl J Med , vol.330 , pp. 235-241
    • Rosenbaum, D.S.1    Jackson, L.E.2    Smith, J.M.3
  • 27
    • 0037823364 scopus 로고    scopus 로고
    • Torsade de pointes due to noncardiac drugs: most patients have easily identifiable risk factors
    • Zeltser D., Justo D., Halkin A., et al. Torsade de pointes due to noncardiac drugs: most patients have easily identifiable risk factors. Medicine (Baltimore) 82 (2003) 282-290
    • (2003) Medicine (Baltimore) , vol.82 , pp. 282-290
    • Zeltser, D.1    Justo, D.2    Halkin, A.3
  • 28
    • 0034083759 scopus 로고    scopus 로고
    • Evidence for a cardiac ion channel mutation underlying drug-induced QT prolongation and life-threatening arrhythmias
    • Napolitano C., Schwartz P.J., Brown A.M., et al. Evidence for a cardiac ion channel mutation underlying drug-induced QT prolongation and life-threatening arrhythmias. J Cardiovasc Electrophysiol 11 (2000) 691-696
    • (2000) J Cardiovasc Electrophysiol , vol.11 , pp. 691-696
    • Napolitano, C.1    Schwartz, P.J.2    Brown, A.M.3
  • 29
    • 0033574273 scopus 로고    scopus 로고
    • MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia
    • Abbott G.W., Sesti F., Splawski I., et al. MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia. Cell 97 (1999) 175-187
    • (1999) Cell , vol.97 , pp. 175-187
    • Abbott, G.W.1    Sesti, F.2    Splawski, I.3
  • 30
    • 0037015231 scopus 로고    scopus 로고
    • Drug-induced long-QT syndrome associated with a subclinical SCN5A mutation
    • Makita N., Horie M., Nakamura T., et al. Drug-induced long-QT syndrome associated with a subclinical SCN5A mutation. Circulation 106 (2002) 1269-1274
    • (2002) Circulation , vol.106 , pp. 1269-1274
    • Makita, N.1    Horie, M.2    Nakamura, T.3
  • 31
    • 0037161355 scopus 로고    scopus 로고
    • Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes
    • Yang P., Kanki H., Drolet B., et al. Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes. Circulation 105 (2002) 1943-1948
    • (2002) Circulation , vol.105 , pp. 1943-1948
    • Yang, P.1    Kanki, H.2    Drolet, B.3
  • 32
    • 18544383162 scopus 로고    scopus 로고
    • Variant of SCN5A sodium channel implicated in risk of cardiac arrhythmia
    • Splawski I., Timothy K.W., Tateyama M., et al. Variant of SCN5A sodium channel implicated in risk of cardiac arrhythmia. Science 297 (2002) 1333-1336
    • (2002) Science , vol.297 , pp. 1333-1336
    • Splawski, I.1    Timothy, K.W.2    Tateyama, M.3
  • 33
    • 0036918695 scopus 로고    scopus 로고
    • SNP S1103Y in the cardiac sodium channel gene SCN5A is associated with cardiac arrhythmias and sudden death in a white family
    • Chen S., Chung M.K., Martin D., et al. SNP S1103Y in the cardiac sodium channel gene SCN5A is associated with cardiac arrhythmias and sudden death in a white family. J Med Genet 39 (2002) 913-915
    • (2002) J Med Genet , vol.39 , pp. 913-915
    • Chen, S.1    Chung, M.K.2    Martin, D.3
  • 34
    • 0032066007 scopus 로고    scopus 로고
    • Taking the "idio" out of "idiosyncratic": predicting torsades de pointes
    • Roden D.M. Taking the "idio" out of "idiosyncratic": predicting torsades de pointes. Pacing Clin Electrophysiol 21 (1998) 1029-1034
    • (1998) Pacing Clin Electrophysiol , vol.21 , pp. 1029-1034
    • Roden, D.M.1
  • 35
    • 16444377083 scopus 로고    scopus 로고
    • Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs
    • Zhou S., Yung Chan S., Cher Goh B., et al. Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs. Clin Pharmacokinet 44 (2005) 279-304
    • (2005) Clin Pharmacokinet , vol.44 , pp. 279-304
    • Zhou, S.1    Yung Chan, S.2    Cher Goh, B.3
  • 36
    • 0027455740 scopus 로고
    • Action potential prolongation exhibits simple dose-dependence for sotalol, but reverse dose-dependence for quinidine and disopyramide: implications for proarrhythmia due to triggered activity
    • Wyse K.R., Ye V., and Campbell T.J. Action potential prolongation exhibits simple dose-dependence for sotalol, but reverse dose-dependence for quinidine and disopyramide: implications for proarrhythmia due to triggered activity. J Cardiovasc Pharmacol 21 (1993) 316-322
    • (1993) J Cardiovasc Pharmacol , vol.21 , pp. 316-322
    • Wyse, K.R.1    Ye, V.2    Campbell, T.J.3
  • 37
    • 0022555299 scopus 로고
    • Incidence and clinical features of the quinidine-associated long QT syndrome: implications for patient care
    • Roden D.M., Woosley R.L., and Primm R.K. Incidence and clinical features of the quinidine-associated long QT syndrome: implications for patient care. Am Heart J 111 (1986) 1088-1093
    • (1986) Am Heart J , vol.111 , pp. 1088-1093
    • Roden, D.M.1    Woosley, R.L.2    Primm, R.K.3
  • 38
    • 0027495872 scopus 로고
    • Antiarrhythmic drugs and torsade de pointes
    • Lazzara R. Antiarrhythmic drugs and torsade de pointes. Eur Heart J 14 Suppl H (1993) 88-92
    • (1993) Eur Heart J , vol.14 , Issue.SUPPL. H , pp. 88-92
    • Lazzara, R.1
  • 39
    • 0020402140 scopus 로고
    • N-acetyl procainamide causing torsades de pointes
    • Olshansky B., Martins J., and Hunt S. N-acetyl procainamide causing torsades de pointes. Am J Cardiol 50 (1982) 1439-1441
    • (1982) Am J Cardiol , vol.50 , pp. 1439-1441
    • Olshansky, B.1    Martins, J.2    Hunt, S.3
  • 40
    • 0033575989 scopus 로고    scopus 로고
    • Dofetilide in patients with congestive heart failure and left ventricular dysfunction. Danish Investigations of Arrhythmia and Mortality on Dofetilide Study Group
    • Torp-Pedersen C., Moller M., Bloch-Thomsen P.E., et al. Dofetilide in patients with congestive heart failure and left ventricular dysfunction. Danish Investigations of Arrhythmia and Mortality on Dofetilide Study Group. N Engl J Med 341 (1999) 857-865
    • (1999) N Engl J Med , vol.341 , pp. 857-865
    • Torp-Pedersen, C.1    Moller, M.2    Bloch-Thomsen, P.E.3
  • 41
    • 0034676762 scopus 로고    scopus 로고
    • Effect of dofetilide in patients with recent myocardial infarction and left-ventricular dysfunction: a randomised trial
    • Kober L., Bloch P., Thomsen E., Moller M., et al. Effect of dofetilide in patients with recent myocardial infarction and left-ventricular dysfunction: a randomised trial. Lancet 356 (2000) 2052-2058
    • (2000) Lancet , vol.356 , pp. 2052-2058
    • Kober, L.1    Bloch, P.2    Thomsen, E.3    Moller, M.4
  • 42
    • 9444256916 scopus 로고    scopus 로고
    • Efficacy of intravenous ibutilide for rapid termination of atrial fibrillation and atrial flutter: a dose-response study
    • Ellenbogen K.A., Stambler B.S., Wood M.A., et al. Efficacy of intravenous ibutilide for rapid termination of atrial fibrillation and atrial flutter: a dose-response study. J Am Coll Cardiol 28 (1996) 130-136
    • (1996) J Am Coll Cardiol , vol.28 , pp. 130-136
    • Ellenbogen, K.A.1    Stambler, B.S.2    Wood, M.A.3
  • 43
    • 0029778315 scopus 로고    scopus 로고
    • Efficacy and safety of repeated intravenous doses of ibutilide for rapid conversion of atrial flutter or fibrillation. Ibutilide Repeat Dose Study Investigators
    • Stambler B.S., Wood M.A., Ellenbogen K.A., et al. Efficacy and safety of repeated intravenous doses of ibutilide for rapid conversion of atrial flutter or fibrillation. Ibutilide Repeat Dose Study Investigators. Circulation 94 (1996) 1613-1621
    • (1996) Circulation , vol.94 , pp. 1613-1621
    • Stambler, B.S.1    Wood, M.A.2    Ellenbogen, K.A.3
  • 44
    • 0028558526 scopus 로고
    • Amiodarone-associated proarrhythmic effects. A review with special reference to torsade de pointes tachycardia
    • Hohnloser S.H., Klingenheben T., and Singh B.N. Amiodarone-associated proarrhythmic effects. A review with special reference to torsade de pointes tachycardia. Ann Intern Med 121 (1994) 529-535
    • (1994) Ann Intern Med , vol.121 , pp. 529-535
    • Hohnloser, S.H.1    Klingenheben, T.2    Singh, B.N.3
  • 45
    • 0030930588 scopus 로고    scopus 로고
    • Adverse effects of low dose amiodarone: a meta-analysis
    • Vorperian V.R., Havighurst T.C., Miller S., et al. Adverse effects of low dose amiodarone: a meta-analysis. J Am Coll Cardiol 30 (1997) 791-798
    • (1997) J Am Coll Cardiol , vol.30 , pp. 791-798
    • Vorperian, V.R.1    Havighurst, T.C.2    Miller, S.3
  • 46
    • 0032191405 scopus 로고    scopus 로고
    • Amiodarone reduces transmural heterogeneity of repolarization in the human heart
    • Drouin E., Lande G., and Charpentier F. Amiodarone reduces transmural heterogeneity of repolarization in the human heart. J Am Coll Cardiol 32 (1998) 1063-1067
    • (1998) J Am Coll Cardiol , vol.32 , pp. 1063-1067
    • Drouin, E.1    Lande, G.2    Charpentier, F.3
  • 47
    • 0026691657 scopus 로고
    • Effects of bepridil on cardiac electrophysiologic properties
    • Prystowsky E.N. Effects of bepridil on cardiac electrophysiologic properties. Am J Cardiol 69 (1992) 63D-67D
    • (1992) Am J Cardiol , vol.69
    • Prystowsky, E.N.1
  • 48
    • 0022612662 scopus 로고
    • Nine cases of torsade de pointes with bepridil administration
    • Manouvrier J., Sagot M., Caron C., et al. Nine cases of torsade de pointes with bepridil administration. Am Heart J 111 (1986) 1005-1007
    • (1986) Am Heart J , vol.111 , pp. 1005-1007
    • Manouvrier, J.1    Sagot, M.2    Caron, C.3
  • 50
    • 0034967764 scopus 로고    scopus 로고
    • Postmarketing reports of QT prolongation and ventricular arrhythmia in association with cisapride and Food and Drug Administration regulatory actions
    • Wysowski D.K., Corken A., Gallo-Torres H., et al. Postmarketing reports of QT prolongation and ventricular arrhythmia in association with cisapride and Food and Drug Administration regulatory actions. Am J Gastroenterol 96 (2001) 1698-1703
    • (2001) Am J Gastroenterol , vol.96 , pp. 1698-1703
    • Wysowski, D.K.1    Corken, A.2    Gallo-Torres, H.3
  • 51
    • 19244365446 scopus 로고    scopus 로고
    • Oral erythromycin and the risk of sudden death from cardiac causes
    • Ray W.A., Murray K.T., Meredith S., et al. Oral erythromycin and the risk of sudden death from cardiac causes. N Engl J Med 351 (2004) 1089-1096
    • (2004) N Engl J Med , vol.351 , pp. 1089-1096
    • Ray, W.A.1    Murray, K.T.2    Meredith, S.3
  • 52
    • 0031944690 scopus 로고    scopus 로고
    • QT prolongation and Torsades de Pointes associated with clarithromycin
    • Lee K.L., Jim M.H., Tang S.C., et al. QT prolongation and Torsades de Pointes associated with clarithromycin. Am J Med 104 (1998) 395-396
    • (1998) Am J Med , vol.104 , pp. 395-396
    • Lee, K.L.1    Jim, M.H.2    Tang, S.C.3
  • 53
    • 0344034363 scopus 로고    scopus 로고
    • Characterization of the inhibitory effects of erythromycin and clarithromycin in the HERG potassium channel
    • Stanat S.J., Carlton C.G., Crumb W.J., et al. Characterization of the inhibitory effects of erythromycin and clarithromycin in the HERG potassium channel. Mol Cell Biochem 254 (2003) 1-7
    • (2003) Mol Cell Biochem , vol.254 , pp. 1-7
    • Stanat, S.J.1    Carlton, C.G.2    Crumb, W.J.3
  • 54
    • 33644846243 scopus 로고    scopus 로고
    • Polymorphic ventricular tachycardia with a normal QT interval following azithromycin
    • Kim M.H., Berkowitz C., and Trohman R.G. Polymorphic ventricular tachycardia with a normal QT interval following azithromycin. Pacing Clin Electrophysiol 28 (2005) 1221-1222
    • (2005) Pacing Clin Electrophysiol , vol.28 , pp. 1221-1222
    • Kim, M.H.1    Berkowitz, C.2    Trohman, R.G.3
  • 55
    • 0036784524 scopus 로고    scopus 로고
    • Divergent proarrhythmic potential of macrolide antibiotics despite similar QT prolongation: fast phase 3 repolarization prevents early afterdepolarizations and torsade de pointes
    • Milberg P., Eckardt L., Bruns H.J., et al. Divergent proarrhythmic potential of macrolide antibiotics despite similar QT prolongation: fast phase 3 repolarization prevents early afterdepolarizations and torsade de pointes. J Pharmacol Exp Ther 303 (2002) 218-225
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 218-225
    • Milberg, P.1    Eckardt, L.2    Bruns, H.J.3
  • 56
    • 0035207325 scopus 로고    scopus 로고
    • A comparative study of the fluoroquinolone antibacterial agents on the action potential duration in guinea pig ventricular myocardia
    • Hagiwara T., Satoh S., Kasai Y., et al. A comparative study of the fluoroquinolone antibacterial agents on the action potential duration in guinea pig ventricular myocardia. Jpn J Pharmacol 87 (2001) 231-234
    • (2001) Jpn J Pharmacol , vol.87 , pp. 231-234
    • Hagiwara, T.1    Satoh, S.2    Kasai, Y.3
  • 57
    • 0035212983 scopus 로고    scopus 로고
    • Rates of torsades de pointes associated with ciprofloxacin, ofloxacin, levofloxacin, gatifloxacin, and moxifloxacin
    • Frothingham R. Rates of torsades de pointes associated with ciprofloxacin, ofloxacin, levofloxacin, gatifloxacin, and moxifloxacin. Pharmacotherapy 21 (2001) 1468-1472
    • (2001) Pharmacotherapy , vol.21 , pp. 1468-1472
    • Frothingham, R.1
  • 58
    • 1542316304 scopus 로고    scopus 로고
    • Torsades de pointes associated with fluoroquinolones: importance of concomitant risk factors
    • Amankwa K., Krishnan S.C., and Tisdale J.E. Torsades de pointes associated with fluoroquinolones: importance of concomitant risk factors. Clin Pharmacol Ther 75 (2004) 242-247
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 242-247
    • Amankwa, K.1    Krishnan, S.C.2    Tisdale, J.E.3
  • 59
    • 0028156730 scopus 로고
    • Incidence of cardiac arrhythmias during intravenous pentamidine therapy in HIV-infected patients
    • Eisenhauer M.D., Eliasson A.H., Taylor A.J., et al. Incidence of cardiac arrhythmias during intravenous pentamidine therapy in HIV-infected patients. Chest 105 (1994) 389-395
    • (1994) Chest , vol.105 , pp. 389-395
    • Eisenhauer, M.D.1    Eliasson, A.H.2    Taylor, A.J.3
  • 60
    • 19944429871 scopus 로고    scopus 로고
    • Pentamidine-induced long QT syndrome and block of hERG trafficking
    • Kuryshev Y.A., Ficker E., Wang L., et al. Pentamidine-induced long QT syndrome and block of hERG trafficking. J Pharmacol Exp Ther 312 (2005) 316-323
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 316-323
    • Kuryshev, Y.A.1    Ficker, E.2    Wang, L.3
  • 61
    • 33749448371 scopus 로고    scopus 로고
    • Torsade de pointes induced by systemic antifungal agents: lessons from a retrospective analysis of published case reports
    • Justo D., and Zeltser D. Torsade de pointes induced by systemic antifungal agents: lessons from a retrospective analysis of published case reports. Mycoses 49 (2006) 463-470
    • (2006) Mycoses , vol.49 , pp. 463-470
    • Justo, D.1    Zeltser, D.2
  • 62
    • 0027404778 scopus 로고
    • Cardiac effects of antimalarial treatment with halofantrine
    • Nosten F., ter Kuile F.O., Luxemburger C., et al. Cardiac effects of antimalarial treatment with halofantrine. Lancet 341 (1993) 1054-1056
    • (1993) Lancet , vol.341 , pp. 1054-1056
    • Nosten, F.1    ter Kuile, F.O.2    Luxemburger, C.3
  • 63
    • 0347948451 scopus 로고    scopus 로고
    • Inhibition of hERG K+ currents by antimalarial drugs in stably transfected HEK293 cells
    • Traebert M., Dumotier B., Meister L., et al. Inhibition of hERG K+ currents by antimalarial drugs in stably transfected HEK293 cells. Eur J Pharmacol 484 (2004) 41-48
    • (2004) Eur J Pharmacol , vol.484 , pp. 41-48
    • Traebert, M.1    Dumotier, B.2    Meister, L.3
  • 64
    • 0036656069 scopus 로고    scopus 로고
    • The effects of antimalarial drugs on ventricular repolarization
    • Touze J.E., Heno P., Fourcade L., et al. The effects of antimalarial drugs on ventricular repolarization. Am J Trop Med Hyg 67 (2002) 54-60
    • (2002) Am J Trop Med Hyg , vol.67 , pp. 54-60
    • Touze, J.E.1    Heno, P.2    Fourcade, L.3
  • 65
    • 0029922080 scopus 로고    scopus 로고
    • Electrocardiographic changes in patients receiving neuroleptic medication
    • Warner J.P., Barnes T.R., and Henry J.A. Electrocardiographic changes in patients receiving neuroleptic medication. Acta Psychiatr Scand 93 (1996) 311-313
    • (1996) Acta Psychiatr Scand , vol.93 , pp. 311-313
    • Warner, J.P.1    Barnes, T.R.2    Henry, J.A.3
  • 66
    • 0347635347 scopus 로고    scopus 로고
    • Mesoridazine: an open-channel blocker of human ether-a-go-go-related gene K+ channel
    • Su Z., Martin R., Cox B.F., et al. Mesoridazine: an open-channel blocker of human ether-a-go-go-related gene K+ channel. J Mol Cell Cardiol 36 (2004) 151-160
    • (2004) J Mol Cell Cardiol , vol.36 , pp. 151-160
    • Su, Z.1    Martin, R.2    Cox, B.F.3
  • 67
    • 0036322892 scopus 로고    scopus 로고
    • Antipsychotic-related QTc prolongation, torsade de pointes and sudden death
    • Haddad P.M., and Anderson I.M. Antipsychotic-related QTc prolongation, torsade de pointes and sudden death. Drugs 62 (2002) 1649-1671
    • (2002) Drugs , vol.62 , pp. 1649-1671
    • Haddad, P.M.1    Anderson, I.M.2
  • 68
    • 0035150202 scopus 로고    scopus 로고
    • Antipsychotic drugs: prolonged QTc interval, torsade de pointes, and sudden death
    • Glassman A.H., and Bigger J.T.J. Antipsychotic drugs: prolonged QTc interval, torsade de pointes, and sudden death. Am J Psychiatry 158 (2001) 1774-1782
    • (2001) Am J Psychiatry , vol.158 , pp. 1774-1782
    • Glassman, A.H.1    Bigger, J.T.J.2
  • 69
    • 0029065958 scopus 로고
    • Case report: reversible QT prolongation with torsades de pointes in a patient with pimozide intoxication
    • Krahenbuhl S., Sauter B., Kupferschmidt H., et al. Case report: reversible QT prolongation with torsades de pointes in a patient with pimozide intoxication. Am J Med Sci 309 (1995) 315-316
    • (1995) Am J Med Sci , vol.309 , pp. 315-316
    • Krahenbuhl, S.1    Sauter, B.2    Kupferschmidt, H.3
  • 70
    • 0034712552 scopus 로고    scopus 로고
    • QTc-interval abnormalities and psychotropic drug therapy in psychiatric patients
    • Reilly J.G., Ayis S.A., Ferrier I.N., et al. QTc-interval abnormalities and psychotropic drug therapy in psychiatric patients. Lancet 355 (2000) 1048-1052
    • (2000) Lancet , vol.355 , pp. 1048-1052
    • Reilly, J.G.1    Ayis, S.A.2    Ferrier, I.N.3
  • 71
    • 0033052403 scopus 로고    scopus 로고
    • Thioridazine lengthens repolarization of cardiac ventricular myocytes by blocking the delayed rectifier potassium current
    • Drolet B., Vincent F., Rail J., et al. Thioridazine lengthens repolarization of cardiac ventricular myocytes by blocking the delayed rectifier potassium current. J Pharmacol Exp Ther 288 (1999) 1261-1268
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 1261-1268
    • Drolet, B.1    Vincent, F.2    Rail, J.3
  • 72
    • 0033373085 scopus 로고    scopus 로고
    • Droperidol lengthens cardiac repolarization due to block of the rapid component of the delayed rectifier potassium current
    • Drolet B., Zhang S., Deschenes D., et al. Droperidol lengthens cardiac repolarization due to block of the rapid component of the delayed rectifier potassium current. J Cardiovasc Electrophysiol 10 (1999) 1597-1604
    • (1999) J Cardiovasc Electrophysiol , vol.10 , pp. 1597-1604
    • Drolet, B.1    Zhang, S.2    Deschenes, D.3
  • 73
    • 4444345419 scopus 로고    scopus 로고
    • Tricyclic antidepressants, QT interval prolongation, and torsade de pointes
    • Vieweg W.V., and Wood M.A. Tricyclic antidepressants, QT interval prolongation, and torsade de pointes. Psychosomatics 45 (2004) 371-377
    • (2004) Psychosomatics , vol.45 , pp. 371-377
    • Vieweg, W.V.1    Wood, M.A.2
  • 74
    • 0034610263 scopus 로고    scopus 로고
    • Prolongation of the QT interval and ventricular tachycardia in patients treated with arsenic trioxide for acute promyelocytic leukemia
    • Ohnishi K., Yoshida H., Shigeno K., et al. Prolongation of the QT interval and ventricular tachycardia in patients treated with arsenic trioxide for acute promyelocytic leukemia. Ann Intern Med 133 (2000) 881-885
    • (2000) Ann Intern Med , vol.133 , pp. 881-885
    • Ohnishi, K.1    Yoshida, H.2    Shigeno, K.3
  • 75
    • 0141939058 scopus 로고    scopus 로고
    • Effect of arsenic trioxide on QT interval in patients with advanced malignancies
    • Barbey J.T., Pezzullo J.C., and Soignet S.L. Effect of arsenic trioxide on QT interval in patients with advanced malignancies. J Clin Oncol 21 (2003) 3609-3615
    • (2003) J Clin Oncol , vol.21 , pp. 3609-3615
    • Barbey, J.T.1    Pezzullo, J.C.2    Soignet, S.L.3
  • 76
    • 0347357886 scopus 로고    scopus 로고
    • Unusual effects of a QT-prolonging drug, arsenic trioxide, on cardiac potassium currents
    • Drolet B., Simard C., and Roden D.M. Unusual effects of a QT-prolonging drug, arsenic trioxide, on cardiac potassium currents. Circulation 109 (2004) 26-29
    • (2004) Circulation , vol.109 , pp. 26-29
    • Drolet, B.1    Simard, C.2    Roden, D.M.3
  • 77
    • 3042528658 scopus 로고    scopus 로고
    • Mechanisms of arsenic-induced prolongation of cardiac repolarization
    • Ficker E., Kuryshev Y.A., Dennis A.T., et al. Mechanisms of arsenic-induced prolongation of cardiac repolarization. Mol Pharmacol 66 (2004) 33-44
    • (2004) Mol Pharmacol , vol.66 , pp. 33-44
    • Ficker, E.1    Kuryshev, Y.A.2    Dennis, A.T.3
  • 78
    • 15244345562 scopus 로고    scopus 로고
    • Impact of methadone treatment on cardiac repolarization and conduction in opioid users
    • Martell B.A., Arnsten J.H., Krantz M.J., et al. Impact of methadone treatment on cardiac repolarization and conduction in opioid users. Am J Cardiol 95 (2005) 915-918
    • (2005) Am J Cardiol , vol.95 , pp. 915-918
    • Martell, B.A.1    Arnsten, J.H.2    Krantz, M.J.3
  • 79
    • 0037674750 scopus 로고    scopus 로고
    • Dose-related effects of methadone on QT prolongation in a series of patients with torsade de pointes
    • Krantz M.J., Kutinsky I.B., Robertson A.D., et al. Dose-related effects of methadone on QT prolongation in a series of patients with torsade de pointes. Pharmacotherapy 23 (2003) 802-805
    • (2003) Pharmacotherapy , vol.23 , pp. 802-805
    • Krantz, M.J.1    Kutinsky, I.B.2    Robertson, A.D.3
  • 80
    • 28044463813 scopus 로고    scopus 로고
    • QT prolongation and torsades de pointes among methadone users: reports to the FDA spontaneous reporting system
    • Pearson E.C., and Woosley R.L. QT prolongation and torsades de pointes among methadone users: reports to the FDA spontaneous reporting system. Pharmacoepidemiol Drug Saf 14 (2005) 747-753
    • (2005) Pharmacoepidemiol Drug Saf , vol.14 , pp. 747-753
    • Pearson, E.C.1    Woosley, R.L.2
  • 81
    • 0022374740 scopus 로고
    • Cesium chloride-induced long QT syndrome: demonstration of afterdepolarizations and triggered activity in vivo
    • Levine J.H., Spear J.F., Guarnieri T., et al. Cesium chloride-induced long QT syndrome: demonstration of afterdepolarizations and triggered activity in vivo. Circulation 72 (1985) 1092-1103
    • (1985) Circulation , vol.72 , pp. 1092-1103
    • Levine, J.H.1    Spear, J.F.2    Guarnieri, T.3
  • 82
    • 0037307310 scopus 로고    scopus 로고
    • Cesium toxicity: a case of self-treatment by alternate therapy gone awry
    • Lyon A.W., and Mayhew W.J. Cesium toxicity: a case of self-treatment by alternate therapy gone awry. Ther Drug Monit 25 (2003) 114-116
    • (2003) Ther Drug Monit , vol.25 , pp. 114-116
    • Lyon, A.W.1    Mayhew, W.J.2
  • 83
    • 0037204187 scopus 로고    scopus 로고
    • Cesium-induced torsades de pointes
    • Pinter A., Dorian P., and Newman D. Cesium-induced torsades de pointes. N Engl J Med 346 (2002) 383-384
    • (2002) N Engl J Med , vol.346 , pp. 383-384
    • Pinter, A.1    Dorian, P.2    Newman, D.3
  • 84
    • 0035034618 scopus 로고    scopus 로고
    • Polymorphic ventricular tachycardia in a woman taking cesium chloride
    • Saliba W., Erdogan O., and Niebauer M. Polymorphic ventricular tachycardia in a woman taking cesium chloride. Pacing Clin Electrophysiol 24 (2001) 515-517
    • (2001) Pacing Clin Electrophysiol , vol.24 , pp. 515-517
    • Saliba, W.1    Erdogan, O.2    Niebauer, M.3
  • 85
    • 0025813533 scopus 로고
    • Induction of arrhythmia by licorice abuse
    • Bocker D., and Breithardt G. Induction of arrhythmia by licorice abuse. Z Kardiol 80 (1991) 389-391
    • (1991) Z Kardiol , vol.80 , pp. 389-391
    • Bocker, D.1    Breithardt, G.2
  • 86
    • 0033001963 scopus 로고    scopus 로고
    • Life-threatening ventricular tachycardia due to liquorice-induced hypokalaemia
    • Eriksson J.W., Carlberg B., and Hillorn V. Life-threatening ventricular tachycardia due to liquorice-induced hypokalaemia. J Intern Med 245 (1999) 307-310
    • (1999) J Intern Med , vol.245 , pp. 307-310
    • Eriksson, J.W.1    Carlberg, B.2    Hillorn, V.3
  • 87
    • 0032501120 scopus 로고    scopus 로고
    • Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions
    • Miller L.G. Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions. Arch Intern Med 158 (1998) 2200-2211
    • (1998) Arch Intern Med , vol.158 , pp. 2200-2211
    • Miller, L.G.1
  • 88
    • 1542318498 scopus 로고    scopus 로고
    • Vitamins, supplements, herbal medicines, and arrhythmias
    • Chung M.K. Vitamins, supplements, herbal medicines, and arrhythmias. Cardiol Rev 12 (2004) 73-84
    • (2004) Cardiol Rev , vol.12 , pp. 73-84
    • Chung, M.K.1
  • 89
    • 1942536148 scopus 로고    scopus 로고
    • Drug-induced torsades de pointes and implications for drug development
    • Fenichel R.R., Malik M., Antzelevitch C., et al. Drug-induced torsades de pointes and implications for drug development. J Cardiovasc Electrophysiol 15 (2004) 475-495
    • (2004) J Cardiovasc Electrophysiol , vol.15 , pp. 475-495
    • Fenichel, R.R.1    Malik, M.2    Antzelevitch, C.3
  • 90
    • 0032109922 scopus 로고    scopus 로고
    • Risks of initiating therapy with sotalol for treatment of atrial fibrillation
    • Marcus F.I. Risks of initiating therapy with sotalol for treatment of atrial fibrillation. J Am Coll Cardiol 32 (1998) 177-180
    • (1998) J Am Coll Cardiol , vol.32 , pp. 177-180
    • Marcus, F.I.1
  • 91
    • 0032127084 scopus 로고    scopus 로고
    • Is hospital admission for initiation of antiarrhythmic therapy with sotalol for atrial arrhythmias required? Yield of in-hospital monitoring and prediction of risk for significant arrhythmia complications
    • Chung M.K., Schweikert R.A., Wilkoff B.L., et al. Is hospital admission for initiation of antiarrhythmic therapy with sotalol for atrial arrhythmias required? Yield of in-hospital monitoring and prediction of risk for significant arrhythmia complications. J Am Coll Cardiol 32 (1998) 169-176
    • (1998) J Am Coll Cardiol , vol.32 , pp. 169-176
    • Chung, M.K.1    Schweikert, R.A.2    Wilkoff, B.L.3
  • 93
    • 0036155193 scopus 로고    scopus 로고
    • Clinical and therapeutic aspects of congenital and acquired long QT syndrome
    • Khan I.A. Clinical and therapeutic aspects of congenital and acquired long QT syndrome. Am J Med 112 (2002) 58-66
    • (2002) Am J Med , vol.112 , pp. 58-66
    • Khan, I.A.1
  • 94
    • 0036855270 scopus 로고    scopus 로고
    • What is the minimal pacing rate that prevents torsades de pointes? Insights from patients with permanent pacemakers
    • Pinski S.L., Eguia L.E., and Trohman R.G. What is the minimal pacing rate that prevents torsades de pointes? Insights from patients with permanent pacemakers. Pacing Clin Electrophysiol 25 (2002) 1612-1615
    • (2002) Pacing Clin Electrophysiol , vol.25 , pp. 1612-1615
    • Pinski, S.L.1    Eguia, L.E.2    Trohman, R.G.3
  • 95
    • 7644243300 scopus 로고    scopus 로고
    • Cardiac pacing: the state of the art
    • Trohman R.G., Kim M.H., and Pinski S.L. Cardiac pacing: the state of the art. Lancet 364 (2004) 1701-1719
    • (2004) Lancet , vol.364 , pp. 1701-1719
    • Trohman, R.G.1    Kim, M.H.2    Pinski, S.L.3
  • 97
    • 0034084919 scopus 로고    scopus 로고
    • Cardiac pacing in the long QT syndrome: review of available data and practical recommendations
    • Viskin S. Cardiac pacing in the long QT syndrome: review of available data and practical recommendations. J Cardiovasc Electrophysiol 11 (2000) 593-600
    • (2000) J Cardiovasc Electrophysiol , vol.11 , pp. 593-600
    • Viskin, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.