Hypoxic condition- and high cell density-induced expression of Redd1 is regulated by activation of hypoxia-inducible factor-1α and Sp1 through the phosphatidylinositol 3-kinase/Akt signaling pathway

Cellular Signalling

Volumn 19, Issue 7, 2007, Pages 1393-1403

  Jin, Hyeon Ok ^a,c   An, Sungkwan ^b   Lee, Hyung Chahn ^a   Woo, Sang Hyeok ^a   Seo, Sung Keum ^a   Choe, Tae Boo ^b   Yoo, Doo Hyun ^a   Lee, Seung Bum ^a   Um, Hong Duck ^a   Lee, Su Jae ^a   Park, Myung Jin ^a   Kim, Jong Il ^c   Hong, Seok Il ^a   Rhee, Chang Hun ^a   Park, In Chul ^a  

^a Korea Institute of Radiation and Medical Science   (South Korea)

^b Konkuk University   (South Korea)

^c Seoul Women University   (South Korea)

Author keywords

Akt; HIF 1 ; PI3K; Redd1; Sp1

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; COBALT CHLORIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; PROTEIN DERIVATIVE; PROTEIN KINASE B; PROTEIN REDD1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL DENSITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPOXIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BINDING SITES; CELL COUNT; CELL HYPOXIA; CONSENSUS SEQUENCE; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTORS;

EID: 34249309925     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2006.12.014     Document Type: Article

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