Leishmania replication protein A-1 binds in vivo single-stranded telomeric DNA

Biochemical and Biophysical Research Communications

Volumn 358, Issue 2, 2007, Pages 417-423

  Neto, J L Siqueira ^a,b   Lira, C B B ^b   Giardini, M A ^a,b   Khater, L ^b   Perez, A M ^a   Peroni, L A ^b   dos Reis, J R R ^b   Freitas Junior, L H ^c   Ramos, C H I ^b   Cano, M I N ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c Institute Pasteur Korea   (South Korea)

Author keywords

Immunolocalization; Leishmania amazonensis; OB fold; Replication protein A 1; Telomere end binding protein

Indexed keywords

REPLICATION PROTEIN A; SINGLE STRANDED DNA;

ARTICLE; DELETION MUTANT; DNA BINDING; LEISHMANIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; SEQUENCE HOMOLOGY; TELOMERE; TRYPANOSOMA;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; DNA; DNA-BINDING PROTEINS; LEISHMANIA; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; REPLICATION PROTEIN A; TELOMERE;

EUKARYOTA; LEISHMANIA AMAZONENSIS; TRYPANOSOMATIDAE;

EID: 34248573511     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.04.144     Document Type: Article

References (33)

1. Wold M.S. Replication protein A: a heterotrimeric, ssDNA-binding protein required for eukaryotic DNA metabolism. Annu. Rev. Biochem. 66 (1997) 61-91
2. Brown L.M., Melendy T., and Ray D.S. Conservation of structure and function of DNA replication protein A in the trypanosomatid Crithidia fasciculata. Proc. Natl. Acad. Sci. USA 89 (1992) 10227-10231
3. Fernández M.F., Castellari R.R., Conte F.F., Gozzo F., Sabino A.A., Pinheiro H., Novello J.C., Eberlin M.N., and Cano M.I.N. Identification of three proteins that associate in vitro with the Leishmania (Leishmania) amazonensis G-rich telomeric strand. Eur. J. Biochem. 271 (2004) 3050-3063
4. Ono Y., Tomita K., Matsuura A., Nakagawa T., Masukata H., Uritani M., Ushimaru T., and Ueno M. A novel allele of fission yeast rad11 that causes defects in DNA repair and telomere length regulation. Nucleic Acids Res. 31 (2003) 7141-7149
5. Smith J., Zou H., and Rothstein R. Characterization of genetic interactions with RFA-1: the role of RPA in DNA replication and telomere maintenance. Biochimie 82 (2000) 71-78
6. Schramke V., Luciano P., Brevet P., Guillot S., Corda Y., Longhese M.P., Gilson E., and Géli V. RPA regulates telomerase action by providing Est1p access to chromosome ends. Nat. Gen. 36 (2004) 46-54
7. Zaug A.J., Podell E.R., and Cech T.R. Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro. Proc. Natl. Acad. Sci. USA 102 (2005) 10864-10869
8. Fang G., and Cech T.R. The beta subunit of Oxytricha telomere binding protein promotes G-quartet formation by telomeric DNA. Cell 74 (1993) 875-885
9. Paeschke K., Simonsson T., Postberg J., Rhodes D., and Lipps H.J. Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo. Nat. Struct. Mol. Biol. 12 (2005) 847-854
10. Salas T.R., Petruseva I., Lavrik O., Bourdoncle A., Mergny J.L., Favre A., and Saintome C. Human replication protein A unfolds telomeric G-quadruplexes. Nucleic Acids Res. 34 (2006) 4857-4865
11. Opresko P.L., von Kobbe C., Laine J.P., Harrigan J., Hickson I.D., and Bohr V.A. Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases. J. Biol. Chem. 277 (2002) 41110-41119
12. Cano M.I.N. Telomere biology of trypanosomatids: more questions than answers. Trends Parasitol. 17 (2001) 425-429
13. Bryan T.M., and Cech T.R. Telomerase and the maintenance of chromosome ends. Curr. Opin. Cell Biol. 11 (1999) 318-324
14. Mitton-Fry R.M., Anderson E.M., Hughes T.R., Lundblad V., and Wuttke D.S. Conserved structure for single-stranded telomeric DNA recognition. Science 296 (2002) 145-147
15. Lowell J.E., and Cross G.A.M. A variant histone H3 is enriched at telomeres in Trypanosoma brucei. J. Cell Sci. 117 (2004) 5937-5947
16. Smogorzewska A., and de Lange T. Regulation of telomerase by telomeric proteins. Annu. Rev. Biochem. 74 (2004) 117-208
17. de Lange T. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev. 19 (2005) 2100-2110
18. Blackburn E.H. Telomeres and telomerase: their mechanisms of action and the effects of altering their functions. FEBS Lett. 579 (2005) 859-862
19. Nugent C.I., Hughes T.R., Lue N.F., and Lundblad V. Cdc13p: a single-strand telomeric DNA binding protein with a dual role in yeast telomere maintenance. Science 274 (1996) 249-252
20. Baumann P., and Cech T.R. POT1, the putative telomere end-binding protein in fission yeast and humans. Science 292 (2001) 1171-1175
21. Shakirov E.V., Surovtseva Y.V., Osbun N., and Shippen D.E. The Arabidopsis POT1 and POT2 proteins function in telomere length homeostasis and chromosome end protection. Mol. Cell. Biol. 25 (2005) 7725-7733
22. Wei C., and Price C.M. Cell cycle localization, dimerization, and binding domain architecture of the telomere protein cPot1. Mol. Cell. Biol. 24 (2004) 2091-2102
23. Gottschling D.E., and Zakian V.A. Telomere proteins: specific recognition and protection of the natural termini of Oxytricha macronuclear DNA. Cell 47 (1986) 195-205
24. Murzin A.G. OB (oligonucleotide/oligosaccharide binding) fold: common structural and functional solution for non-homologous sequences. EMBO J. 12 (1993) 861-867
25. Theobald D.L., and Wuttke D.S. Prediction of multiple tandem OB-fold domains in telomere end-binding proteins POT1 and Cdc13. Structure 12 (2004) 1877-1879
26. Cohen S., Jacoband E., and Manor H. Effects of single-stranded DNA binding proteins on primer extension by telomerase. Biochim. Biophys. Acta 1679 (2004) 129-140
27. Bastin-Shanower S.A., and Brill S.J. Functional analysis of the four DNA binding domains of replication protein A. The role of RPA2 in ssDNA binding. J. Biol. Chem. 276 (2001) 36446-36453
28. Lei M., Podell E.R., Baumann P., and Cech T.R. DNA self-recognition in the structure of POT1 bound to telomeric single-stranded DNA. Nature 426 (2003) 198-203
29. Xin H., Liu D., Wan M., Safari A., Kim H., Sun W., O'Connor M.S., and Songyang Z. TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase. Nature 445 (2007) 559-562
30. Bochkareva E., Korolev S., Lees-Miller S.P., and Bochkarev A. Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA. EMBO J. 21 (2002) 1855-1863
31. Anderson E.M., Halsey W.A., and Wuttke D.S. Delineation of the high-affinity single-stranded telomeric DNA-binding domain of Saccharomyces cerevisiae Cdc13. Nucleic Acids Res. 30 (2002) 4305-4313
32. El-Sayed N.M., Myler P., Bartholomeu D.C., Nilsson D., Aggarwal G., Tran A.-N., Ghedin E., Worthey E.A., Delcher A., Blandin G., Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B., Anupama A., Arner E., Aslund L., Attipoe A., Bontempi E., Bringaud F., Burton P., Cadag E., Campbell D.A., et al. The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science 309 (2005) 409-415
33. Gao H., Cervantes R.B., Mandell E.K., Otero J.H., and Lundblad V. RPA-like proteins mediate yeast telomere function. Nat. Struct. Mol. Biol. 14 (2007) 208-214