Heterologous viral RNA export elements improve expression of severe acute respiratory syndrome (SARS) coronavirus spike protein and protective efficacy of DNA vaccines against SARS

Virology

Volumn 363, Issue 2, 2007, Pages 288-302

  Callendret, Benoît ^a   Lorin, Valérie ^a   Charneau, Pierre ^b   Marianneau, Philippe ^d   Contamin, Hugues ^d   Betton, Jean Michel ^c   van der Werf, Sylvie ^a   Escriou, Nicolas ^a  

^a CNRS   (France)

^b Groupe à 5 ans de Virologie Moléculaire et de Vectorologie   (France)

^c INSTITUT PASTEUR   (France)

^d Institut Pasteur   (France)

Author keywords

Coronavirus; CTE; DNA vaccine; Severe acute respiratory syndrome; Spike glycoprotein; Viral RNA export element; WPRE

Indexed keywords

DNA VACCINE; GLYCOPROTEIN SPIKE; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN; VIRUS RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; DNA IMMUNIZATION; EXPRESSION VECTOR; FEMALE; HEPATITIS VIRUS; HUMAN; IMMUNOBLOTTING; IMMUNOGENICITY; LOW DRUG DOSE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARS CORONAVIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; SIMIAN VIRUS;

ANIMALS; ANTIBODIES, VIRAL; CELL LINE; ENHANCER ELEMENTS (GENETICS); FEMALE; GENE EXPRESSION REGULATION; GENETIC VECTORS; HEPATITIS B VIRUS, WOODCHUCK; HUMANS; IMMUNIZATION; INJECTIONS, INTRAMUSCULAR; MASON-PFIZER MONKEY VIRUS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; NEUTRALIZATION TESTS; PLASMIDS; SARS VIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; TRANSFECTION; VACCINES, DNA; VIRAL ENVELOPE PROTEINS; VIRAL VACCINES;

ANIMALIA; CORONAVIRUS; MUS; RNA VIRUSES; SARS CORONAVIRUS; WOODCHUCK HEPATITIS VIRUS;

EID: 34248543396     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2007.01.012     Document Type: Article

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