Single amino acid substitutions in the severe acute respiratory syndrome coronavirus spike glycoprotein determine viral entry and immunogenicity of a major neutralizing domain

Journal of Virology

Volumn 79, Issue 18, 2005, Pages 11638-11646

  Yi, Christopher E ^a   Ba, Lei ^a   Zhang, Linqi ^a   Ho, David D ^a   Chen, Zhiwei ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; DIPEPTIDYL CARBOXYPEPTIDASE; DNA VACCINE; NEUTRALIZING ANTIBODY; VIRUS GLYCOPROTEIN; VIRUS SPIKE PROTEIN; VIRUS VACCINE;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; ELECTROPORATION; FEMALE; GENE DELETION; HUMAN; HUMAN CELL; IMMUNOGENICITY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SARS CORONAVIRUS; VACCINATION; VIRUS DNA CELL DNA INTERACTION; VIRUS NEUTRALIZATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; CELL LINE; FEMALE; HUMANS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON; MUTAGENESIS, SITE-DIRECTED; NEUTRALIZATION TESTS; PROTEIN STRUCTURE, TERTIARY; SARS VIRUS; SEQUENCE DELETION; VACCINES, DNA; VIRAL ENVELOPE PROTEINS; VIRAL VACCINES; VIRULENCE;

ANIMALIA; CORONAVIRUS; SARS COV;

EID: 24644508802     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.18.11638-11646.2005     Document Type: Article

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