Determination of binding constant and stoichiometry for antibody-antigen interaction with surface plasmon resonance

Current Proteomics

Volumn 3, Issue 4, 2006, Pages 271-282

  Lin, Shiming ^a,c,d   Lee, Adam Shih Yuan ^b   Lin, Chih Chen ^b   Lee, Chih Kung ^c  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TAMKANG UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Affinity; Antigen binding fragment; Association rate constant; Binding constant; Dissociation constant; Dissociation rate constant; Maximum binding ratio; Monoclonal antibody; Stoichiometry; Surface plasmon resonance; Variable single chain fragment

Indexed keywords

EID: 34248380793     PISSN: 15701646     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016406780655586     Document Type: Review

References (52)

1. Beernink, P. T., Hwang, M., Ramirez, M., Murphy, M. B., Doyle, S. A. and Thelen, M. P. (2005) Specificity of protein interactions mediated by BRCT domains of the XRCC1 DNA repair protein. J. Biol. Chem. 280: 30206-13.
2. Berzofsky, J. A. and Berkower, I. J. (1983) in: W.E. Paul (Ed.) Antibodyantigen interaction. CRC Press, Boca Raton, FL., pp. 595-644.
3. Biemann, H. P. and Koshland, D. E. (1994) The proteinase: mucus proteinase inhibitor binding stoichiometry. J. Biol. Chem. 267: 4370-5.
4. Biorn, A. C., Cocklin, S., Madani, N., Si, Z., Ivanovic, T., Samanen, J., Ryk, D. I. V., Pantophlet, R., et al. (2004) Model of action for linear peptide inhibitors of HIV-1 gp120 interactions. Biochemistry 43: 1928-38.
5. Boghaert, E. R., Sridharan, L., Armellino, D. C., Khandke, K. M., DiJoseph, J. F., Kunz, A., Dougher, M. M., Jiang, F., et al. (2004) Antibodytargeted chemotherapy with the calicheamicin conjugate hu3S193-Nacetyl g calicheamicin dimethyl hydrazide targets Lewis and eliminates Lewis-positive human carcinoma cells and xenografts. Clin. Cancer Res. 10: 4538-49.
6. Canziani, G. A., Klakamp, S. and Myszka, D. G. (2004) Kinetics screening of antibodies from crude hybridoma samples using Biacore. Anal. Biochem. 325: 301-7.
7. Carrasco, C., Facompré, M., Chisholm, J. D., Vranken, D. L. V., Wilson, W. D. and Bailly, C. (2002) Nucleic Acids Res. 30: 1774-81.
8. Chaudhury, C., Brooks, C. L., Carter, D. C., Robinson, J. M. and Anderson, C. L. (2006) Albumin binding to FcRn: Distinct from the FcRn-IgG interaction. Biochemistry 45: 4983-90.
9. Davies, J. (1994) Review:Surface plasmon resonance-The technique and its applications to biomaterial processes. Nanobiology 3: 5-16.
10. Djavadi-Ohaniance, L. and Friguet, B. (1992) The immunochemistry of solid-phase immunoassay. CRC Press, Boca Raton, FL, pp. 201-6.
11. Drake, A. W., Myszka, D. G. and Klakamp, S. L. (2004) Characterizing high-affinity antigen/antibody complexes by kinetic- and equilibriumbased methods. Anal. Biochem. 328: 35-43.
12. Dubreuil, O., Bossus, M., Graille, M., Bilous, M., Savatier, A., Jolivet, M., Ménez, A., Stura, E., et al. (2005) Fine tuning of the specificity of an anti-progesterone antibody by first and second sphere residue engineering. J. Biol. Chem. 280: 24880-7.
13. Fountoulakis, M., Zulauf, M., Lustig, A. and Garotta, G. (1992) Stoichiometry of interaction between interferon gamma and its receptor. Eur. J. Biochem. 208: 781-7.
14. Glaser, R.W. (1993) Antigen-antibody binding and mass transport by convection and diffusion to a surface: a two-dimensional computer model of binding and dissociation kinetics. Anal. Biochem. 213: 152-61.
15. Goldberg, M. (1991) Investigating protein conformation, dynamics and folding with monoclonal antibodies. TIBS 16: 358-62.
16. Gomes, P. and Andreu, D. (2002) Direct kinetic assay of interactions between small peptides and immobilized antibodies using a surface plasmon resonance biosensor. J. Immunol. Methods 259: 217-30.
17. Herr, A. B., White, C. L., Milburn, C., Wu, C. and Bjorkman, P. J. (2003) Bivalent binding of IgA1 to FcaRI suggests a mechanism for cytokine activation of IgA phagocytosis. J. Mol. Biol. 327: 645-57.
18. Huang, B. C., Davern, S. and Kennel, S. J. (2006) Mono and bivalent binding of scFv and covalent diabody to murine laminin-1 using radioiodinated proteins and SPR measurements: effects on tissue retention in vivo. J. Immunol. Methods 313: 149-60.
19. Ja, W. W., Olsen, B. N. and Roberts, R. W. (2005) Epitope mapping using mRNA display and a unidirectional nested deletion library. Protein Eng. Des. Sel. 18: 309-19.
20. Johansson, R., Ohlin, M., Jansson, B. and Ohlson, S. (2006) Transiently binding antibody fragments against Lewis x and sialyl-Lewis x. J. Immunol. Methods 312: 20-6.
21. Jonsson, U. (1992) Real time BIA. A new biosensor based technology for the direct measurement of biomolecular interactions. Biosensors: Fundamentals, Technologies and Applications. Ed. Scheller F. and Schmid R. D., pp. 467-476.
22. Katsamba, P. S., Navratilova, I., Calderon-Cacia, M., Fan, L., Thornton, K., Zhu, M., Bos, T. V., Forte, C., et al. (2006) Kinetic analysis of a highaffinity antibody/antigen interaction performed by multiple Biacore users. Anal. Biochem. 352: 208-21.
23. Lackmann, M., Bucci, T., Mann, R. J., Kravets, L. A., Viney, E., Smith, F., Moritz, R. L., Carter, W., et al. (1996) Purification of a ligand for the EPH-like receptor HEK using a biosensor-based affinity detection approach. Proc. Natl. Acad. Sci. USA 93: 2523-7.
24. Leickt, L., Grubb, A. and Ohlson, S. (2002) Development of monoclonal antibodies against creatine kinase MB2. Scand J. Clin. Lab. Invest. 62: 423-30.
25. Lin, L.-P., Huang, L.-S., Lin, C.-W., Lee, C.-K., Chen, J.-L., Hsu, S.-M. and Lin, S. (2005) Determination of binding constant of DNA-binding drug to target DNA by surface plasmon resonance biosensor technology. Curr. Drug Targets 5: 61-72.
26. Liu, X., Wei, J., Song, D., Zhang, Z., Zhang, H. and Luo, G. (2003) Determination of affinities and antigenic epitopes of bovine cardiac troponin I (cTnI) with monoclonal antibodies by surface plasmon resonance biosensor. Anal. Biochem. 314: 301-9.
27. Liu, Z., Li, F. and Huang, Y. (1999) Determination of unbound drug concentration and protein-drug binding fraction in plasma. Biomed. Chromatogr. 13: 262-6.
28. Ma, Q., Shimaoka, M., Lu, C., Jing, H., Carman, C. V. and Springer, T. A. (2002) Activation-induced conformational changes in the I domain region of lymphocyte function-associated antigen 1. J. Biol. Chem. 277: 10638-41.
29. Markey, F. (1999) What is SPR anyway? BIA. J. 6: 14-7.
30. Markgren, P.-O., Hämäläinen, M. and Danielson, U. (1999) Screening of compounds interacting with HIV-1 proteinase using optical biosensor technology. Anal. Biochem. 265: 340-50.
31. Mazur, S., Tanious, F. A., Ding, D., Kumar, A., Boykin, D. W., Simpson, I. J., Neidle, S. and Wilson, W. D. (2000) A thermodynamic and structural analysis of DNA minor-groove complex formation. J. Mol. Biol. 300: 321-37.
32. Mimura, Y., Sondermann, P., Ghirlando, R., Lund, J., Young, S. P., Goodall, M. and Jefferis, R. (2001) Role of oligosaccharide residues of IgG1-Fc in FccRIIb binding. J. Biol. Chem. 276: 45539-45547.
33. Morton, T. A. and Myszka, D. G. (1998) Kinetic analysis of macromolecular interactions using surface plasmon resonance biosensors. Methods Enzymol. 295: 268-94.
34. Myszka, D. G. (1999) Survey of the 1998 optical biosensor literature. J. Mol. Recognit. 12: 390-408.
35. Myszka, D. G., Jonsen, M. D. and Graves, B. J. (1998) Equilibrium analysis of high affinity interactions using BIACORE. Anal. Biochem. 265: 326-30.
36. Nguyen, B., Tardy, C., Bailly, C., Colson, P., Houssier, C., Kumar, A., Boykin, D. W. and Wilson, W. D. (2002) Influence of compound structure on affinity, sequence selectivity, and mode of binding to DNA for unfused aromatic dications related to furamidine. Biopolymers 63: 281-97.
37. Oda, M. and Azuma T. (2000) Reevaluation of stoichiometry and affinity/ avidity in interactions between anti-hapten antibodies and mono- or multi-valent antigens. Mol. Immunol. 37: 1111-22.
38. Oda, M., Uchiyama, S., Robinson, C. V., Fukui, K., Kobayashi, Y. and Azuma, T. (2006) Regional and segmental flexibility of antibodies in interaction with antigens of different size. FEBS J. 273: 1476-87.
39. Okun, V. M., Moser, R., Blaas, D. and Kenndler, E. (2001) Complexes between monoclonal antibodies and receptor fragments with a common cold virus: determination of stoichiometry by capillary electrophoresis. Anal. Chem. 73: 3900-6.
40. Paetz, A., Sack, M., Thepen, T., Tur, M. K., Bruell, D., Finnern, R., Fischer, R. and Barth, S. (2005) Recombinant soluble human Fcg receptor I with picomolar affinity for immunoglobulin G. Biochem. Biophys. Res. Commun. 338: 1811-7.
41. Ricard-Blum, S., Bernocco, S., Font, B., Moali, C. Eichenberger, D., Farjane, J., Burchardt, E. R., van der Rest, M., et al. (2002) Interaction properties of the procollagen C-proteinase enhancer protein shed light on the mechanism of stimulation of BMP-1. J. Biol. Chem. 277: 33864-9.
42. Rich, R. L. and Myszka, D. G. (2000) Advances in surface plasmon resonance biosensor analysis. Curr. Opin. Biotech. 11: 54-61.
43. Roos, H., Karlsson, R., Nilshans, H. and Persson, A. (1998) Thermodynamic analysis of protein interactions with biosensor technology. J. Mol. Recognit. 11: 204-10.
44. Russo, K., Ragone, R., Facchiano, A. M., Capogrossi, M. C. and Facchiano, A. (2002) Platelet-derived growth factor-BB abd basic fibroblast growth factor directly interact in vitro with high affinity. J. Biol. Chem. 277: 1284-91.
45. Sagawa, T., Oda, M., Ishimura, M., Furukawa, K. and Azuma, T. (2003) Thermodynamic and kinetic aspects of antibody evolution during the immune response to hapten. Mol. Immunol. 39: 801-8.
46. Son, J. H., Lee, U. H., Lee, J. J., Kwon, B., Kwon, B. S. and Park, J. W. (2004) Humanization of agonistic anti-human 4-1BB monoclonal antibody using a phag-displayed combinatorial library. J. Immunol. Methods 286: 187-201.
47. Teulade-Fichou, M. P., Carrasco, C., Guittat, L., Bailly, C., Alberti, P., Mergny, J. L., David, A., Lehn, J. M., et al. (2003) Selective recognition of G-qQuadruplex telomeric DNA by a bis(quinacridine) macrocycle. J. Am. Chem. Soc. 125: 4732-40.
48. Tobita, T., Oda, M. and Azuma, T. (2004) Segmental flexibility and avidity of IgM in the interaction of polyvalent antigens. Mol. Immunol. 40: 803-11.
49. Verel, I., Heider, K. H., Siegmund, M., Ostermann, E., Patzelt, E., Sproll, M., Snow, G. B., Adolf, G. R., et al. (2002) Tumor targeting properties of monoclonal antibodies with different affinity for target antigen CD44V6 in nude mice bearing head-and-neck cancer xenografts. Int. J. Cancer 99: 396-402.
50. Wittel, U. A., Jain, M., Goel, A., Baranowska-Kortylewicz, J., Kurizaki, T., Chauhan, S. C., Agrawal, D. K., Colcher, D., et al. (2005) Engineering and characterization of a divalent single-chain Fv angiotensin II fusion contruct of the monoclonal antibody CC49. Biochem. Biophys. Res. Commun. 329: 168-76.
51. Yang, C. Y., Brooks, E., Li, Y., Denny, P., Ho, C. M., Qi, F., Shi, W., Wolinsky, L., et al. (2005) Detection of picomolar levels of interleukin-8 in human saliva by SPR. Lab Chip 5: 1017-23.
52. Zeder-Lutz, G., Neurath, A. R. and Van Regenmortel, M. H. (1999) Kinetics of interaction between 3-hydroxyphthaloyl-beta-lactoglobulin and CD4 molecules. Biologicals 27: 29-34.