The regulation of protein synthesis and translation factors by CD3 andCD28in human primary T lymphocytes

BMC Biochemistry

Volumn 3, Issue , 2002, Pages 1-12

  Kleijn, Miranda ^a   Proud, Christopher G ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CAP BINDING PROTEIN; CD28 ANTIGEN; CD3 ANTIGEN; ELONGATION FACTOR 2; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INITIATION FACTOR; INITIATION FACTOR 2; INITIATION FACTOR 4E; INITIATION FACTOR 4F; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY ALPHACD28; MONOCLONAL ANTIBODY ALPHACD3; S6 KINASE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL STIMULATION; COMPLEX FORMATION; CONTROLLED STUDY; DEPHOSPHORYLATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS REGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

EUKARYOTA;

EID: 34248376930     PISSN: 14712091     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2091-3-11     Document Type: Article

References (59)

1. Haghighat A, Sonenberg N: eIF4G dramatically enhances the binding of eIF4E to the mRNA 5′-cap structure. J Biol Chem 1997, 272:21677-21680
2. Gingras AC, Raught B, Sonenberg N: eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annu Rev Biochem 1999, 68:913-963
3. Rozen F, Edery I, Meerovitch K, Dever TE, Merrick WC, Sonenberg N: Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F. Mol Cell Biol 1990, 10:1134-1144
4. Lawson TG, Lee KA, Maimone MM, Abramson RD, Dever TE, Merrick WC, Thach RE: Dissociation of double-stranded polynucleotide helical structures by eukaryotic initiation factors, as revealed by a novel assay. Biochemistry 1989, 28:4729-4734
5. Richter-Cook NJ, Dever TE, Hensold JO, Merrick WC: Purification and characterization of a new eukaryotic protein translation factor. Eukaryotic initiation factor 4H. J Biol Chem 1998, 273:7579-7587
6. Redpath NT, Foulstone EJ, Proud CG: Regulation of translation elongation factor-2 by insulin via a rapamycin-sensitive signalling pathway. EMBO J 1996, 15:2291-2297
7. Redpath NT, Price NT, Severinov KV, Proud CG: Regulation of elongation factor-2 by multisite phosphorylation. Eur J Biochem 1993, 213:689-699
8. Ahern T, Kay JE: Control of protein synthesis during lymphocyte stimulation. Biochem J 1971, 125:73P-74P
9. Cooke A, Kay JE, Cooper HL: Ribonucleic acid polymerase activity as a measure of ribonucleic acid synthesis. Biochem J 1971, 125:74P
10. Kay JE, Ahern T, Lindsay VJ, Sampson J: The control of protein synthesis during the stimulation of lymphocytes by phytohaemagglutinin. III. Poly(U) translation and the rate of polypeptide chain elongation. Biochim Biophys Acta 1975, 378:241-250
11. Kay JE, Ahern T, Atkins M: Control of protein synthesis during the activation of lymphocytes by phytohaemagglutinin. Biochim Biophys Acta 1971, 247:322-334
12. Mao X, Green JM, Safer B, Lindsten T, Frederickson RM, Miyamoto S, Sonenberg N, Thompson CB: Regulation of translation initiation factor gene expression during human T cell activation. J Biol Chem 1992, 267:20444-20450
13. Kleijn M, Scheper GC, Voorma HO, Thomas AAM: Regulation of translation initiation factors by signal transduction. Eur J Biochem 1998, 253:531-544
14. Morley SJ, Rau M, Kay JE, Pain VM: Increased phosphorylation of eukaryotic initiation factor 4 alpha during early activation of T lymphocytes correlates with increased initiation factor 4F complex formation. Eur J Biochem 1993, 218:39-48
15. Boal TR, Chiorini JA, Cohen RB, Miyamoto S, Frederickson RM, Sonenberg N, Safer B: Regulation of eukaryotic translation initiation factor expression during T-cell activation. Biochim Biophys Acta 1993, 1176:257-264
16. Miyamoto S, Kimball SR, Safer B: Signal transduction pathways that contribute to increased protein synthesis during T-cell activation. Biochim Biophys Acta 2000, 1494:28-42
17. Morley SJ: Signalling through either the p38 or ERK mitogen-activated protein (MAP) kinase pathway is obligatory for phorbol ester and T cell receptor complex (TCR-CD3)-stimulated phosphorylation of initiation factor (eIF) 4E in Jurkat T cells. FEBS Lett 1997, 418:327-332
18. Lin TA, Kong X, Haystead TA, Pause A, Belsham G, Sonenberg N, Lawrence JC Jr: PHAS-I as a link between mitogen-activated protein kinase and translation initiation [see comments]. Science 1994, 266:653-656
19. Pause A, Belsham GJ, Gingras AC, Donze O, Lin TA, Lawrence JC Jr, Sonenberg N: Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5′-cap function [see comments]. Nature 1994, 371:762-767
20. Brunn GJ, Williams J, Sabers C, Wiederrecht G, Lawrence JC Jr, Abraham RT: Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. EMBO J 1996, 15:5256-5267
21. Beretta L, Singer NG, Hinderer R, Gingras AC, Richardson B, Hanash SM, Sonenberg N: Differential regulation of translation and eIF4E phosphorylation during human thymocyte maturation. J Immunol 1998, 160:3269-3273
22. Kimball SR, Horetsky RL, Jefferson LS: Implication of eIF2B rather than eIF4E in the regulation of global protein synthesis by amino acids in L6 myoblasts. J Biol Chem 1998, 273:30945-30953
23. Kleijn M, Welsh GI, Scheper GC, Voorma HO, Proud CG, Thomas AAM: Nerve and epidermal growth factor induce protein synthesis and eIF2B activation in PC12 cells. J Biol Chem 1998, 273:5536-5541
24. Welsh GI, Loughlin AJ, Foulstone EJ, Price NT, Proud CG: Regulation of initiation factor eIF-2B by GSK-3 regulated phosphorylation. Biochem Soc Trans 1997, 25:191S
25. Welsh GI, Miyamoto S, Price NT, Safer B, Proud CG: T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3. J Bio Chem 1996, 271:11410-11413
26. Singh LP, Wahba AJ: Regulation of protein synthesis in eukaryotic cells by the guanine nucleotide exchange factor and chain initiation factor 2. SAAS Bull Biochem Biotechnol 1996, 9:1-8
27. Noel PJ, Boise LH, Green JM, Thompson CB: CD28 costimulation prevents cell death during primary T cell activation. J Immunol 1996, 157:636-642
28. Radvanyi LG, Shi Y, Vaziri H, Sharma A, Dhala R, Mills GB, Miller RG: CD28 costimulation inhibits TCR-induced apoptosis during a primary T cell response. J Immunol 1996, 156:1788-1798
29. Cantrell D: T cell antigen receptor signal transduction pathways. Annu Rev Immunol 1996, 14:259-274
30. Wang X, Flynn A, Waskiewicz AJ, Webb BL, Vries RG, Baines IA, Cooper JA, Proud CG: The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways. J Bio Chem 1998, 273:9373-9377
31. Haghighat A, Mader S, Pause A, Sonenberg N: Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E. EMBO J 1995, 14:5701-5709
32. Grolleau A, Kaplan MJ, Hanash SM, Beretta L, Richardson B: Impaired translational response and increased protein kinase PKR expression in T cells from lupus patients. J Clin Invest 2000, 106:1561-1568
33. Welsh GI, Miller CM, Loughlin AJ, Price NT, Proud CG: Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin. FEBS Lett 1998, 421:125-130
34. Jefferson LS, Fabian JR, Kimball SR: Glycogen synthase kinase-3 is the predominant insulin-regulated eukaryotic initiation factor 2B kinase in skeletal muscle. Int J Biochem Cell Biol 1999, 31:191-200
35. Pap M, Cooper GM: Role of Translation Initiation Factor 2B in Control of Cell Survival by the Phosphatidylinositol 3-Kinase/Akt/Glycogen Synthase Kinase 3beta Signaling Pathway. Mol Cell Biol 2002, 22:578-586
36. Jefferies HB, Fumagalli S, Dennis PB, Reinhard C, Pearson RB, Thomas G: Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k. EMBO J 1997, 16:3693-3704
37. Tang H, Hornstein E, Stolovich M, Levy G, Livingstone M, Templeton D, Avruch J, Meyuhas O: Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation. Mol Cell Bio 2001, 21:8671-8683
38. Jedlicka P, Panniers R: Mechanism of activation of protein synthesis initiation in mitogen-stimulated T lymphocytes. J Biol Chem 1991, 266:15663-15669
39. Miyamoto S, Chiorini JA, Urcelay E, Safer B: Regulation of gene expression for translation initiation factor eIF-2 alpha: importance of the 3′ untranslated region. Biochem J 1996, 315:791-798
40. Kimball SR, Horetsky RL, Jefferson LS: Signal transduction pathways involved in the regulation of protein synthesis by insulin in L6 myoblasts. Am J Physiol 1998, 274:C221-228
41. Rao GN, Madamanchi NR, Lele M, Gadiparthi L, Gingras AC, Eling TE, Sonenberg N: A potential role for extracellular signal-regulated kinases in prostaglandin F2alpha-induced protein synthesis in smooth muscle cells. J Biol Chem 1999, 274:12925-12932
42. Quevedo C, Alcazar A, Salinas M: Two different signal transduction pathways are implicated in the regulation of initiation factor 2B activity in insulin-like growth factor-1-stimulated neuronal cells. J Biol Chem 2000, 275:19192-19197
43. Herbert TP, Kilhams GR, Batty IH, Proud CG: Distinct signalling pathways mediate insulin and phorbol ester-stimulated eukaryotic initiation factor 4F assembly and protein synthesis in HEK 293 cells. J Biol Chem 2000, 275:11249-11256
44. Kleijn M, Proud CG: The activation of eukaryotic initiation factor (eIF)2B by growth factors in PC12 cells requires MEK/ERK signalling. FEBS Lett 2000, 476:262-265
45. Dardevet D, Sornet C, Vary T, Grizard J: Phosphatidylinositol 3-kinase and p70 s6 kinase participate in the regulation of protein turnover in skeletal muscle by insulin and insulin-like growth factor I. Endocrinology 1996, 137:4087-4094
46. Bragado MJ, Groblewski GE, Williams JA: Regulation of protein synthesis by cholecystokinin in rat pancreatic acini involves PHAS-I and the p70 S6 kinase pathway. Gastroenterology 1998, 115:733-742
47. Wang L, Wang X, Proud CG: Activation of mRNA translation in rat cardiac myocytes by insulin involves multiple rapamycin-sensitive steps. Am J Physiol Heart Circ Physiol 2000, 278:H1056-1068
48. Pai SY, Calvo V, Wood M, Bierer BE: Cross-linking CD28 leads to activation of 70-kDa S6 kinase. Eur J Immunol 1994, 24:2364-2368
49. Han JW, Pearson RB, Dennis PB, Thomas G: Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites. J Bio Chem 1995, 270:21396-21403
50. Igarashi M, Yamaguchi H, Hirata A, Daimon M, Tominaga M, Kato T: Insulin activates p38 mitogen-activated protein (MAP) kinase via a MAP kinase kinase (MKK) 3/MKK 6 pathway in vascular smooth muscle cells. Eur J Clin Invest 2000, 30:668-677
51. Horstmann S, Kahle PJ, Borasio GD: Inhibitors of p38 mitogen-activated protein kinase promote neuronal survival in vitro. J Neurosci Res 1998, 52:483-490
52. Lali FV, Hunt AE, Turner SJ, Foxwell BM: The pyridinyl imidazole inhibitor SB203580 blocks phosphoinositide-dependent protein kinase activity, protein kinase B phosphorylation, and retinoblastoma hyperphosphorylation in interleukin-2-stimulated T cells independently of p38 mitogen-activated protein kinase. J Biol Chem 2000, 275:7395-7402
53. Wang L, Gout I, Proud CG: Cross-talk between the ERK and p70 S6 kinase (S6K) signaling pathways. MEK-dependent activation of S6K2 in cardiomyocytes. J Bio Chem 2001, 276:32670-32677
54. Welsh GI, Stokes CM, Wang X, Sakaue H, Ogawa W, Kasuga M, Proud CG: Activation of translation initiation factor eIF2B by insulin requires phosphatidyl inositol 3-kinase. FEBS Lett 1997, 410:418-422
55. McLeod LE, Wang L, Proud CG: beta-Adrenergic agonists increase phosphorylation of elongation factor 2 in cardiomyocytes without eliciting calcium-independent eEF2 kinase activity. FEBS Lett 2001, 489:225-228
56. Wang X, Campbell LE, Miller CM, Proud CG: Amino acid availability regulates p70 S6 kinase and multiple translation factors. Biochem J 1998, 334:261-267
57. Moule SK, Edgell NJ, Welsh GI, Diggle TA, Foulstone EJ, Heesom KJ, Proud CG, RM Denton: Multiple signalling pathways involved in the stimulation of fatty acid and glycogen synthesis by insulin in rat epididymal fat cells. Biochem J 1995, 311:595-601
58. Kleijn M, Proud CG: Glucose and amino acids modulate translation factor activation by growth factors in PC12 cells. Biochem J 2000, 347:399-406
59. Kleijn M, Voorma HO, Thomas AAM: Phosphorylation of eIF-4E and initiation of protein synthesis in P19 embryonal carcinoma cells. J Cell Biochem 1995, 59:443-452