Phosphatidylinositol 3-kinase and p70 S6 kinase participate in the regulation of protein turnover in skeletal muscle by insulin and insulin- like growth factor I

Endocrinology

Volumn 137, Issue 10, 1996, Pages 4087-4094

  Dardevet, Dominique ^a   Sornet, Claire ^a   Vary, Thomas ^b   Grizard, Jean ^a  

^a CEMAGREF   (France)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; RAPAMYCIN; SOMATOMEDIN C; WORTMANNIN;

ANIMAL TISSUE; ARTICLE; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; GLUCOSE TRANSPORT; MUSCLE METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS REGULATION; RAT; RIBOSOME SUBUNIT; SKELETAL MUSCLE;

EID: 0029779604     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.10.8828461     Document Type: Article

References (42)

1. Myers MG, White MF 1993 The new elements of insulin signaling-insulin receptor substrate-1 and proteins with SH2 domains. Diabetes 42:643-650
2. Freeman RM, Plutzky J, Neel BG 1992 Identification of a human src homology2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew. Proc Natl Acad Sci USA 89:11239-11243
3. Denton RM, Tavare JM 1995 Does mitogen-activated-protein kinase have a role in insulin action? The cases for and against. Eur J Biochem 227:597-611
4. Okada T, Kawano Y, Sakakibara T, Hazeki O, Ui M 1994 Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes-studies with a selective inhibitor wortmannin. J Biol Chem 269:3568-3573
5. Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR 1994 Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol 14:4902-4911
6. Yeh JI, Gulve EA, Rameh L, Birnbaum MJ 1995 The effects of wortmannin on rat skeletal muscle dissociation of signaling pathways for insulin- and contraction-activated hexose transport. J Biol Chem 270:2107-2111
7. Dent P, Lavoinne A, Nakielny S, Caudwell FB, Watt P, Cohen P 1990 The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle. Nature 348:302-308
8. Lavoinne A, Erikson E, Maller JL, Price DJ, Avruch J, Cohen P 1991 Purification and characterisation of the insulin-stimulated protein kinase from rabbit skeletal muscle-close similarity to S6 kinase-II. Eur J Biochem 199:723-728
9. Sutherland C, Campbell DG, Cohen P 1993 Identification of insulin-stimulated protein kinase-1 as the rabbit equivalent of rskmo-2. Identification of two threonines phosphorylated during activation by mitogen-activated protein kinase. Eur J Biochem 212:581-588
10. Kimball SR, Vary TC, Jefferson LS 1994 Regulation of protein synthesis by insulin. Annu Rev Physiol 56:321-348
11. Welsh GI, Proud CG 1993 Glycogen synthetase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor elF-2B. Biochem J 294:625-629
12. Welsh GI, Foulstone EJ, Young SW, Tavare JM, Proud CG 1994 Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase. Biochem J 303:15-20
13. Haystead TAJ, Haystead CMM, Hu CB, Lin TA, Lawrence Jr JC 1994 Phosphorylation of PHAS-I by mitogen-activated protein (MAP) kinase-identification of a site phosphorylated by MAP kinase in vitro and in response to insulin in rat adipocytes. J Biol Chem 269:23185-23191
14. Lin TA, Kong XM, Haystead TAJ, Pause A, Belsham G, Sonenberg N, Lawrence Jr JC 1994 PHAS-1 as a link between mitogen-activated protein kinase and translation initiation. Science 266:653-656
15. Ferrari S, Thomas G 1994 S6 phosphorylation and the p70(s6k)/p85(s6k). Crit Rev Biochem Mol Biol 29:385-413
16. Kettelhut IC, Wing SS, Goldberg AL 1988 Endocrine regulation of protein breakdown in skeletal muscle. Diabetes Metab Rev 4:751-772
17. Attaix D, Taillandier D, Temparis S, Larbaud D, Aurousseau E, Combaret L, Voisin L 1994 Regulation of ATP-ubiquitin-dependent proteolysis in muscle wasting. Reprod Nutr Dev 34:583-597
18. Dardevet D, Sornet C, Taillandier D, Savary I, Attaix D, Grizard J 1995 Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats. J Clin Invest 96:2113-2119
19. Duckworth WC, Bennett RG, Hamel FG 1994 A direct inhibitory effect of insulin on a cytosolic proteolytic complex containing insulin-degrading enzyme and multicatalytic proteinase. J Biol Chem 269:24575-24580
20. Wing SS, Banville D 1994 14-kDa ubiquitin-conjugating enzyme: structure of the rat gene and regulation upon tasting and by insulin. Am J Physiol 267:E39-E48
21. Dardevet D, Sornet C, Attaix D, Baracos VE, Grizard J 1994 Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats. Endocrinology 134:1475-1484
22. Larbaud D, Debras E, Taillandier D, Samuels SE, Temparis S, Champredon C, Grizard J, Attaix D, Euglycemic hyperinsulinemia hyperaminoacidemia decreases skeletal muscle ubiquitin mRNA in goats. Am J Pathol, in press
23. Tischler ME, Desautels M, Goldberg AL 1982 Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle? J Biol Chem 257:1613-1621
24. Dardevet D, Komori K, Grunfeld C, Rosenzweig SA, Buse M 1991 Increased hepatic insulin proreceptor/receptor ratio in diabetes: a possible processing defect. Am J Physiol 261:E562-E571
25. Petritsch C, Woscholski R, Edelmann HML, Parker PJ, Ballou LM 1995 Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinaso inhibitors. Eur J Biochem 230:431-438
26. Chung JK, Grammer TC, Lemon KP, Kazlauskas A, Blenis J 1994 PDGF- and insulin-dependent pp70(S6k) activation mediated by phosphatidylinositol-3-OH kinase. Nature 370:71-75
27. Cross DAE, Alessi DR, Vandenheede JR, McDowell HE, Hundal HS, Cohen P 1994 The inhibition of glycogen svnthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between ras and rat. Biochem J 303:21-26
28. Zhou GX, Meier KE, Buse MG 1993 Sequential activation of two mitogen activated protein (Map) kinase isoforms in rat skeletal muscle following insulin injection. Biochem Biophys Res Commun 197:578-584
29. Heydrick SJ, Julien D, Gautier N, Tanti JF, Giorgetti S, Van Obberghen E, Lemarchand-Brustel Y 1993 Defect in skeletal muscle phosphatidylinositol-3-kinase in obese insulin-resistant mice. J Clin Invest 91:1358-1366
30. Le Marchand-Brustel Y, Gatier N, Cormont M, Van Obberghen E 1995 Wortmannin inhibits the action of insulin but not that of okadaic acid in skeletal muscle: comparison with fat cells. Endocrinology 136:3564-3570
31. Folli F, Saad MJA, Backer JM, Kahn CR 1993 Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin resistant and insulin-deficient diabetes-mellitus. J Clin Invest 92:1787-1794
32. Saad MJA, Folli F, Kahn JA, Kahn CR 1993 Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats. J Clin Invest 92:2065-2072
33. Vlahos C, Matter W, Hui K, Brown R 1994 A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4 morphonyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269:5241-5248
34. Terada N, Patel HR, Takase K, Kohno K, Nairn AC, Gelfand EW 1994 Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins. Proc Natl Acad Sci USA 91:11477-11481
35. Hei YJ, McNeill JH, Sanghera JS, Diamond J, Bryer-Ash M, Pelech SL 1993 Characterization of insulin-stimulated seryl/threonyl protein kinases in rat skeletal muscle. J Biol Chem 268:13203-13213
36. Haystead TAJ, Weiel JE, Lichfield DW, Tsukitani Y, Fischer EH, Krebs EG 1990 Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2A in attenuation of the signal. J Biol Chem 265:16571-16580
37. Ray LB, Sturgill TW 1987 Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro. Proc Natl Acad Sci USA 84:1502-1506
38. Dickens M, Chin JE, Roth RA, Ellis L, Denton RM, Tavare JM 1992 Characterization of insulin-stimulated protein serine/threonine kinases in CHO cells expressing human insulin receptors with point and deletion mutations. Biochem J 287:201-209
39. Gould GW, Merrall NW, Martin S, Jess TJ, Campbell IW, Calderhead DM, Gibbs EM, Holman GD, Plevin RJ 1994 Growth factor-induced stimulation of hexose transport in 3T3-L1 adipocytes: evidence that insulin-induced translocation of GLUT4 is independent of activation of MAP kinase. Cell Signal 6:313-320
40. Wiese RJ, Mastick CC, Lazar DF, Saltiel AR 1995 Activation of mitogen-activated protein kinase and phosphatidylinositol 3′-kinase is not sufficient for the hormonal stimulation of glucose uptake, lipogenesis, or glycogen synthesis in 3T3-L1 adipocytes. J Biol Chem 270:3442-3446
41. Lazar DF, Wiese RJ, Brady MJ, Mastick CC, Waters SB, Yamauchi K, Pessin JE, Cuatrecasas P, Saltiel AR 1995 Mitogen-activated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin. J Biol Chem 270:20801-20807
42. Cormont M, Tanti JF, Zahraoui A, Van Obberghen E, Le Marchand-Brustel Y 1994 Rab4 is phosphorylated by the insulin-activated extracellular-signal-regulated kinase erk1. Eur J Biochem 219:1081-1085