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Volumn 85, Issue 2, 2007, Pages 101-109

Hormonal signaling and pituitary adenomas

Author keywords

G protein; GNAS1 mutation; Hypothalamic neurohormones; Pituitary adenomas

Indexed keywords

CYCLIC AMP; GROWTH FACTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; HORMONE RECEPTOR; NEUROHORMONE;

EID: 34248231793     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000100440     Document Type: Conference Paper
Times cited : (18)

References (66)
  • 1
    • 0033915227 scopus 로고    scopus 로고
    • Molecular pathogenesis of pituitary tumors
    • Farrel WE, Clayton RN: Molecular pathogenesis of pituitary tumors. Front Neuroendocrinol 2000;21:174-198.
    • (2000) Front Neuroendocrinol , vol.21 , pp. 174-198
    • Farrel, W.E.1    Clayton, R.N.2
  • 2
    • 0036831826 scopus 로고    scopus 로고
    • The pathogenesis of pituitary tumours
    • Asa SL, Ezzat S: The pathogenesis of pituitary tumours. Nat Rev Cancer 2002;2:836-849.
    • (2002) Nat Rev Cancer , vol.2 , pp. 836-849
    • Asa, S.L.1    Ezzat, S.2
  • 4
    • 1942469957 scopus 로고    scopus 로고
    • Molecular targets in pituitary tumours
    • Heaney AP, Melmed S: Molecular targets in pituitary tumours. Nat Rev Cancer 2004;4:285-295.
    • (2004) Nat Rev Cancer , vol.4 , pp. 285-295
    • Heaney, A.P.1    Melmed, S.2
  • 5
    • 33845395600 scopus 로고    scopus 로고
    • Mechanisms of disease: Mutations of G proteins and protein-coupled receptors in endocrine diseases
    • Lania AG, Mantovani G, Spada A: Mechanisms of disease: mutations of G proteins and protein-coupled receptors in endocrine diseases. Nat Clin Pract Endocrinol Metab 2006;2:681-693.
    • (2006) Nat Clin Pract Endocrinol Metab , vol.2 , pp. 681-693
    • Lania, A.G.1    Mantovani, G.2    Spada, A.3
  • 7
    • 0019508599 scopus 로고
    • Microadenomas of the pituitary and abnormal sella tomograms in an unselected autopsy series
    • Burrow GN, Wortzman G, Rewcastle NB, Hodgate RC, Kovacs K: Microadenomas of the pituitary and abnormal sella tomograms in an unselected autopsy series. N Engl J Med 1981;304:156-158.
    • (1981) N Engl J Med , vol.304 , pp. 156-158
    • Burrow, G.N.1    Wortzman, G.2    Rewcastle, N.B.3    Hodgate, R.C.4    Kovacs, K.5
  • 8
    • 0027409868 scopus 로고
    • Modern imaging of the pituitary
    • Elster AD: Modern imaging of the pituitary. Radiology 1993;187:1-14.
    • (1993) Radiology , vol.187 , pp. 1-14
    • Elster, A.D.1
  • 11
    • 0033119604 scopus 로고    scopus 로고
    • Chromosome 13q deletion mapping in pituitary tumors: Infrequent loss of the retinoblastoma susceptibility gene (RB1) despite loss of RB1 product in somatotropinomas
    • Simpson DJ, Magnay J, Bicknell JE, Barkan AL, McNicol AM, Clayton RN, Farrel WE: Chromosome 13q deletion mapping in pituitary tumors: Infrequent loss of the retinoblastoma susceptibility gene (RB1) despite loss of RB1 product in somatotropinomas. Cancer Res 1999;59:1562-1566.
    • (1999) Cancer Res , vol.59 , pp. 1562-1566
    • Simpson, D.J.1    Magnay, J.2    Bicknell, J.E.3    Barkan, A.L.4    McNicol, A.M.5    Clayton, R.N.6    Farrel, W.E.7
  • 18
    • 0031670782 scopus 로고    scopus 로고
    • Overexpression of vasopressin (V3) and corticotrophin-releasing hormone receptor genes in corticotroph tumours
    • De Keyzer Y, Rene P, Beldjord C, Lenne F, Bertagna X: Overexpression of vasopressin (V3) and corticotrophin-releasing hormone receptor genes in corticotroph tumours. Clin Endocrinol (Oxf) 1998;49:475-482.
    • (1998) Clin Endocrinol (Oxf) , vol.49 , pp. 475-482
    • De Keyzer, Y.1    Rene, P.2    Beldjord, C.3    Lenne, F.4    Bertagna, X.5
  • 20
    • 0019411063 scopus 로고
    • Altered dopaminergic regulation of thyrotropin release in patients with prolactinomas: Comparison with other tests of hypothalamic-pituitary function
    • Scanlon MF, Rodriguez-Arnao MD, McGregor AM, Weightman D, Lewis M, Cook DB, Gomez-Pan A, Hall R: Altered dopaminergic regulation of thyrotropin release in patients with prolactinomas: comparison with other tests of hypothalamic-pituitary function. Clin Endocrinol 1981;14:133-149.
    • (1981) Clin Endocrinol , vol.14 , pp. 133-149
    • Scanlon, M.F.1    Rodriguez-Arnao, M.D.2    McGregor, A.M.3    Weightman, D.4    Lewis, M.5    Cook, D.B.6    Gomez-Pan, A.7    Hall, R.8
  • 22
    • 0033303537 scopus 로고    scopus 로고
    • Pituitary lactotroph adenomas develop after prolonged lactotroph hyperplasia in dopamine D2 receptor-deficient mice
    • Asa SL, Kelly MA, Grandy DK, Low MJ: Pituitary lactotroph adenomas develop after prolonged lactotroph hyperplasia in dopamine D2 receptor-deficient mice. Endocrinology 1999;140:5348-5355.
    • (1999) Endocrinology , vol.140 , pp. 5348-5355
    • Asa, S.L.1    Kelly, M.A.2    Grandy, D.K.3    Low, M.J.4
  • 27
    • 17744378733 scopus 로고    scopus 로고
    • Human somatostatin receptor subtypes in acromegaly: Distinct patterns of messenger ribonucleic acid expression and hormone suppression identify different tumoral phenotypes
    • Jaquet P, Saveanu A, Gunz G, Fina F, Zamora AJ, Grino M, Culler MD, Moreau JP, Enjalbert A, Ouafik LH: Human somatostatin receptor subtypes in acromegaly: distinct patterns of messenger ribonucleic acid expression and hormone suppression identify different tumoral phenotypes. J Clin Endocrinol Metab 2000;85:781-792.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 781-792
    • Jaquet, P.1    Saveanu, A.2    Gunz, G.3    Fina, F.4    Zamora, A.J.5    Grino, M.6    Culler, M.D.7    Moreau, J.P.8    Enjalbert, A.9    Ouafik, L.H.10
  • 28
    • 0023522307 scopus 로고
    • Altered Gs and adenylate cyclase activity in human GH-secreting pituitary adenomas
    • Vallar L, Spada A, Giannattasio G: Altered Gs and adenylate cyclase activity in human GH-secreting pituitary adenomas. Nature 1987;330:566-567.
    • (1987) Nature , vol.330 , pp. 566-567
    • Vallar, L.1    Spada, A.2    Giannattasio, G.3
  • 29
    • 0024404145 scopus 로고
    • GTPase inhibiting mutations activate the α chain of Gs and stimulate adenylyl cyclase in human pituitary tumours
    • Landis C, Masters SB, Spada A, Pace AM, Bourne HR, Vallar L: GTPase inhibiting mutations activate the α chain of Gs and stimulate adenylyl cyclase in human pituitary tumours. Nature 1989;340:692-696.
    • (1989) Nature , vol.340 , pp. 692-696
    • Landis, C.1    Masters, S.B.2    Spada, A.3    Pace, A.M.4    Bourne, H.R.5    Vallar, L.6
  • 30
    • 0027202237 scopus 로고
    • Clinical and biochemical characteristics of acromegalic patients harboring gsp-positive and gsp-negative pituitary tumors
    • Adams EF, Brockmeier S, Friedmann E, Roth M, Buchfelder M, Fahlbusch R: Clinical and biochemical characteristics of acromegalic patients harboring gsp-positive and gsp-negative pituitary tumors. Neurosurgery 1993;33:198-200.
    • (1993) Neurosurgery , vol.33 , pp. 198-200
    • Adams, E.F.1    Brockmeier, S.2    Friedmann, E.3    Roth, M.4    Buchfelder, M.5    Fahlbusch, R.6
  • 31
    • 0029882954 scopus 로고    scopus 로고
    • Characteristics of gsp-positive growth hormone-secreting pituitary tumors in Korean acromegalic patients
    • Yang I, Park S, Ryu M, Woo J, Kim S, Kim J, Kim Y, Choi Y: Characteristics of gsp-positive growth hormone-secreting pituitary tumors in Korean acromegalic patients. Eur J Endocrinol 1996;134:720-726.
    • (1996) Eur J Endocrinol , vol.134 , pp. 720-726
    • Yang, I.1    Park, S.2    Ryu, M.3    Woo, J.4    Kim, S.5    Kim, J.6    Kim, Y.7    Choi, Y.8
  • 35
    • 0033955375 scopus 로고    scopus 로고
    • Absence of somatostatin receptor type 2 A mutations and gip oncogene in pituitary somatotroph adenomas
    • Petersenn S, Heyens M, Ludecke DK, Beil FU, Schulte HM: Absence of somatostatin receptor type 2 A mutations and gip oncogene in pituitary somatotroph adenomas. Clin Endocrinol (Oxf) 2000;52:35-42.
    • (2000) Clin Endocrinol (Oxf) , vol.52 , pp. 35-42
    • Petersenn, S.1    Heyens, M.2    Ludecke, D.K.3    Beil, F.U.4    Schulte, H.M.5
  • 36
    • 0030656476 scopus 로고    scopus 로고
    • Immunodetection of G proteins in human pituitary adenomas: Evidence for a low expression of proteins of the Gi subfamily
    • Ballarè E, Mantovani S, Bassetti M, Lania A, Spada A: Immunodetection of G proteins in human pituitary adenomas: evidence for a low expression of proteins of the Gi subfamily. Eur J Endocrinol 1997;137:482-489.
    • (1997) Eur J Endocrinol , vol.137 , pp. 482-489
    • Ballarè, E.1    Mantovani, S.2    Bassetti, M.3    Lania, A.4    Spada, A.5
  • 38
    • 0032723515 scopus 로고    scopus 로고
    • Mutation analysis of protein kinase A catalytic subunit in thyroid adenomas and pituitary tumours
    • Esapa CT, Harris PE: Mutation analysis of protein kinase A catalytic subunit in thyroid adenomas and pituitary tumours. Eur J Endocrinol 1999;141:409-412.
    • (1999) Eur J Endocrinol , vol.141 , pp. 409-412
    • Esapa, C.T.1    Harris, P.E.2
  • 42
    • 0032788576 scopus 로고    scopus 로고
    • Quantitative analysis of growth-related factors in human pituitary adenomas - lowered insulin-like growth factor-I and its receptor mRNA in growth hormone-producing adenomas
    • Otsuka E, Tamiya T, Yamauchi T, Ogura T, Ohmoto T, Makino M: Quantitative analysis of growth-related factors in human pituitary adenomas - lowered insulin-like growth factor-I and its receptor mRNA in growth hormone-producing adenomas. Regul Pept 1999;63:31-38.
    • (1999) Regul Pept , vol.63 , pp. 31-38
    • Otsuka, E.1    Tamiya, T.2    Yamauchi, T.3    Ogura, T.4    Ohmoto, T.5    Makino, M.6
  • 43
    • 0029122724 scopus 로고
    • Targeting of transforming growth factor-α expression to pituitary lactotrophs in transgenic mice results in selective lactotroph proliferation and adenomas
    • McAndrew J, Paterson AJ, Asa SL, McCarthy KJ, Kudlow JE: Targeting of transforming growth factor-α expression to pituitary lactotrophs in transgenic mice results in selective lactotroph proliferation and adenomas. Endocrinology 1995;136:4479-4488.
    • (1995) Endocrinology , vol.136 , pp. 4479-4488
    • McAndrew, J.1    Paterson, A.J.2    Asa, S.L.3    McCarthy, K.J.4    Kudlow, J.E.5
  • 44
    • 0030064976 scopus 로고    scopus 로고
    • Epidermal growth factor and its receptor (EGF-R) in human pituitary adenomas: EGF-R correlates with tumor aggressiveness
    • LeRiche V, Asa S, Ezzat S: Epidermal growth factor and its receptor (EGF-R) in human pituitary adenomas: EGF-R correlates with tumor aggressiveness. J Clin Endocrinol Metab 1996;81:656-662.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 656-662
    • LeRiche, V.1    Asa, S.2    Ezzat, S.3
  • 45
    • 0028912517 scopus 로고
    • Heterogeneous in vivo and in vitro expression of basic fibroblast growth factor by human pituitary adenomas
    • Ezzat S, Smyth HS, Ramyar L, Asa S: Heterogeneous in vivo and in vitro expression of basic fibroblast growth factor by human pituitary adenomas. J Clin Endocrinol Metab 1995;80:878-884.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 878-884
    • Ezzat, S.1    Smyth, H.S.2    Ramyar, L.3    Asa, S.4
  • 46
    • 0025724116 scopus 로고
    • Transforming DNA sequences present in human prolactin-secreting pituitary tumors
    • Gonsky R, Herman V, Melmed S, Fagin J: Transforming DNA sequences present in human prolactin-secreting pituitary tumors. Mol Endocrinol 1991;5:1687-1695.
    • (1991) Mol Endocrinol , vol.5 , pp. 1687-1695
    • Gonsky, R.1    Herman, V.2    Melmed, S.3    Fagin, J.4
  • 47
    • 0036144332 scopus 로고    scopus 로고
    • Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis
    • Ezzat S, Zheng L, Zhu XF, Wu GE, Asa SL: Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis. J Clin Invest 2002;109:69-74.
    • (2002) J Clin Invest , vol.109 , pp. 69-74
    • Ezzat, S.1    Zheng, L.2    Zhu, X.F.3    Wu, G.E.4    Asa, S.L.5
  • 48
    • 0034945537 scopus 로고    scopus 로고
    • N-CAM modulates tumourcell adhesion to matrix by inducing FGF-receptor signalling
    • Cavallaro U, Niedermeyer J, Fuxa M, Christofori G: N-CAM modulates tumourcell adhesion to matrix by inducing FGF-receptor signalling. Nat Cell Biol 2001;3:650-657.
    • (2001) Nat Cell Biol , vol.3 , pp. 650-657
    • Cavallaro, U.1    Niedermeyer, J.2    Fuxa, M.3    Christofori, G.4
  • 49
    • 0005597998 scopus 로고
    • Direct arterial vascularization of estrogen induced prolactin-secreting anterior pituitary tumor
    • Elias KA, Weiner RI: Direct arterial vascularization of estrogen induced prolactin-secreting anterior pituitary tumor. Proc Natl Acad Sci USA 1984;81:4549-4553.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 4549-4553
    • Elias, K.A.1    Weiner, R.I.2
  • 51
    • 0035725597 scopus 로고    scopus 로고
    • In vitro secretion of FSH by cultured clinically nonfunctioning and gonadotroph pituitary adenomas is directly correlated with locally produced levels of activin A
    • Wessels HT, Hofland LJ, van der Wal R, van Gastel L, van Koetsveld PM, de Herder WW, de Jong FH: In vitro secretion of FSH by cultured clinically nonfunctioning and gonadotroph pituitary adenomas is directly correlated with locally produced levels of activin A. Clin Endocrinol (Oxf) 2001;54:485-492.
    • (2001) Clin Endocrinol (Oxf) , vol.54 , pp. 485-492
    • Wessels, H.T.1    Hofland, L.J.2    van der Wal, R.3    van Gastel, L.4    van Koetsveld, P.M.5    de Herder, W.W.6    de Jong, F.H.7
  • 52
    • 0034534149 scopus 로고    scopus 로고
    • Truncated activin type I receptor Alk4 isoforms are dominant negative receptors inhibiting activin signaling
    • Zhou Y, Sun H, Danila DC, Johnson SR, Sigai DP, Xun Zhang X, Klibanski A: Truncated activin type I receptor Alk4 isoforms are dominant negative receptors inhibiting activin signaling. Mol Endocrinol 2000;14:2066-2075.
    • (2000) Mol Endocrinol , vol.14 , pp. 2066-2075
    • Zhou, Y.1    Sun, H.2    Danila, D.C.3    Johnson, S.R.4    Sigai, D.P.5    Xun Zhang, X.6    Klibanski, A.7
  • 53
    • 0035398487 scopus 로고    scopus 로고
    • G-protein-coupled receptors and signaling networks: Emerging paradigms
    • Marinissen MJ, Gutkind JS: G-protein-coupled receptors and signaling networks: emerging paradigms. Trends Pharmacol Sci 2001;22:368-376.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 368-376
    • Marinissen, M.J.1    Gutkind, J.S.2
  • 54
    • 0034119581 scopus 로고    scopus 로고
    • Activation of MAPK cascades by G-protein-coupled receptors: The case of gonadotropin-releasing hormone receptor
    • Naor Z, Benard O, Seger R: Activation of MAPK cascades by G-protein-coupled receptors: the case of gonadotropin-releasing hormone receptor. Trends Endocrinol Metab 2000;11:91-99.
    • (2000) Trends Endocrinol Metab , vol.11 , pp. 91-99
    • Naor, Z.1    Benard, O.2    Seger, R.3
  • 55
    • 0038359744 scopus 로고    scopus 로고
    • Effects of hypothalamic neuropeptides on extracellular signal-regulated kinase (ERK1 and ERK2) cascade in human tumoral pituitary cells
    • Lania A, Filopanti M, Corbetta S, Losa M, Ballare E, Beck-Peccoz P, Spada A: Effects of hypothalamic neuropeptides on extracellular signal-regulated kinase (ERK1 and ERK2) cascade in human tumoral pituitary cells. J Clin Endocrinol Metab 2003;88:1692-1696.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1692-1696
    • Lania, A.1    Filopanti, M.2    Corbetta, S.3    Losa, M.4    Ballare, E.5    Beck-Peccoz, P.6    Spada, A.7
  • 57
    • 0036607064 scopus 로고    scopus 로고
    • Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation
    • Stork PJ, Schmitt JM Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation. Trends Cell Biol 2002;12:258-266.
    • (2002) Trends Cell Biol , vol.12 , pp. 258-266
    • Stork, P.J.1    Schmitt, J.M.2
  • 58
    • 27644575157 scopus 로고    scopus 로고
    • Coordinating ERK/MAPK signalling through scaffolds and inhibitors
    • Kolch W: Coordinating ERK/MAPK signalling through scaffolds and inhibitors Nat Rev Mol Cell Biol 2005;6:827-838.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 827-838
    • Kolch, W.1
  • 59
    • 0006654781 scopus 로고
    • Spontaneous basophilic tumor of the pituitary gland in gonadectomized mice
    • Dickie MM, Wolley GW: Spontaneous basophilic tumor of the pituitary gland in gonadectomized mice. Cancer Res 1949;16:372-384.
    • (1949) Cancer Res , vol.16 , pp. 372-384
    • Dickie, M.M.1    Wolley, G.W.2
  • 60
    • 0006656051 scopus 로고
    • The mechanism of induction and the characteristics of pituitary tumors induced by thyroidectomy
    • Furth J, Dent NN, Burnett WT: The mechanism of induction and the characteristics of pituitary tumors induced by thyroidectomy. J Clin Endocrinol Metab 1955;15:81-87.
    • (1955) J Clin Endocrinol Metab , vol.15 , pp. 81-87
    • Furth, J.1    Dent, N.N.2    Burnett, W.T.3
  • 61
    • 0022125745 scopus 로고
    • Gonadotropin cell adenomas of the pituitary
    • Snyder PJ: Gonadotropin cell adenomas of the pituitary. Endocr Rev 1985;6:552-564.
    • (1985) Endocr Rev , vol.6 , pp. 552-564
    • Snyder, P.J.1
  • 63
    • 0030179298 scopus 로고    scopus 로고
    • Karl M, Lamberts SW, Koper JW, Katz DA, Huizenga NE, Kino T, Haddad BR, Hughes MR: Chrousos GP. Cushing's disease preceded by generalized glucocorticoid resistance: clinical consequences of a novel, dominantnegative glucocorticoid receptor mutation. Proc Assoc Am Physicians 1996;108:296-307.
    • Karl M, Lamberts SW, Koper JW, Katz DA, Huizenga NE, Kino T, Haddad BR, Hughes MR: Chrousos GP. Cushing's disease preceded by generalized glucocorticoid resistance: clinical consequences of a novel, dominantnegative glucocorticoid receptor mutation. Proc Assoc Am Physicians 1996;108:296-307.
  • 65
    • 0034747060 scopus 로고    scopus 로고
    • Somatic mutation of TRβ can cause a defect in negative regulation of TSH in a TSH-secreting pituitary tumor
    • Ando S, Sarlis NJ, Oldfield EH, Yen PM: Somatic mutation of TRβ can cause a defect in negative regulation of TSH in a TSH-secreting pituitary tumor. J Clin Endocrinol Metab 2001;86:5572-5576.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5572-5576
    • Ando, S.1    Sarlis, N.J.2    Oldfield, E.H.3    Yen, P.M.4


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