Characteristics of gsp-positive growth hormone-secreting pituitary tumors in Korean acromegalic patients

European Journal of Endocrinology

Volumn 134, Issue 6, 1996, Pages 720-726

  Yang, Inmyung ^a   Park, Seungjoon ^a   Ryu, Meesook ^a   Woo, Jeongtaek ^a   Kim, Sungwoon ^a   Kim, Jinwoo ^a   Kim, Youngseol ^a   Choi, Youngkil ^a  

^a Kyung Hee University Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BROMOCRIPTINE; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; OCTREOTIDE; PROLACTIN; PROTIRELIN;

ACROMEGALY; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HYPOPHYSIS TUMOR; KOREA; MALE; MOLECULAR BIOLOGY; MUTATION; PRIORITY JOURNAL;

EID: 0029882954     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1340720     Document Type: Article

References (23)

1. S and adenylate cyclase activity in human GH-secreting pituitary adenomas. Nature 1987;330:566-8
2. S and stimulate adenylyl cyclase in human pituitary tumours. Nature 1989;340:692-6
3. Lyons J, Landis CA, Harsh G, Vallar L, Grunewald K, Feichtinger H, et al. Two G protein oncogenes in human endocrine tumours. Science 1990;249:655-9
4. Clementi E, Malgaretti N, Meldolesi J, Taramelli R. A new constitutively activating mutation of the Gs protein α subunit-gsp oncogene is found in human pituitary tumours. Oncogene 1990;5:1959-61
5. Harris PE, Alexander JM, Bikkal HA, Hsu DW, Hedley-Whyte ET, Klibanski A, et al. Glycoprotein hormone α-subunit production in somatotroph adenomas with and without GSα mutations. J Clin Endocrinol Metab 1992;75:918-23
6. Drews RT, Gravel RA, Collu R. Identification of G protein subunit mutations in human growth hormone (GH)- and GH/prolactin-secreting pituitary tumors by single-strand conformation polymorphism (SSCP) analysis. Mol Cell Endocrinol 1992;87:125-9
7. Adams EF, Brockmeier S, Friedmann E, Roth M, Buchfelder M, Fahlbusch R. Clinical and biochemical characteristics of acromegalic patients harboring gsp-positive and gsp-negative pituitary tumors. Neurosurgery 1993;33:198-203
8. Sα gene in growth hormone-secreting pituitary adenomas by the polymerase chain reaction-direct sequencing method using paraffin-embedded tissues. Acta Endocrinol 1993;129:301-6
9. Yoshimoto K, Iwahana H, Fukuda A, Sano T, Itakura M. Rare mutations of the Gs alpha subunit gene in human endocrine tumors. Cancer 1993;72:1386-93
10. Yang IM, Woo JT, Kim SW, Kim JW, Kim YS, Choi YK. Characteristics of acromegalic patients with a good response to octreotide, a somatostatin analogue. Clin Endocrinol 1995;42: 295-301
11. Goelz SE, Hamilton SR, Vogelstein B. Purification of DNA from formaldehyde fixed and paraffin embedded human tissue. Biochem Biophys Res Commun 1987;130:118-26
12. Hedges LV and Olkin I. Statistical methods for meta-analysis. 1st ed. New York: Academic Press, 1985
13. Suarez HG, du Villard JA, Caillou B, Schlumberger M, Parmentier C, Monier R. gsp mutations in human thyroid tumours. Oncogene 1991;6:677-9
14. Sα alter stimulation of adenylyl cyclase. J Biol Chem 1989;264: 15467-74
15. Sα. J Biol Chem 1989;264:15475-82
16. S protein. J Clin Endocrinol Metab 1990;71:1416-20
17. Spada A, Arosio M, Bochicchio D, Bazzoni N, Vallar L, Bassette M, et al. Clinical, biochemical, and morphological correlates in patients bearing growth hormone-secreting pituitary tumors with or without constitutively active adenylyl cyclase. J Clin Endocrinol Metab 1990;71:1421-6
18. 3 Pituitary cells stimulates prolactin promoter activity. J Biol Chem 1994;269:33-6
19. Moyse E, Le Dafniet M, Epelbaum J, Pagesy P, Peillon F, Kordon C, et al. Somatostatin receptors in human growth hormone and prolactin-secreting pituitary adenomas. J Clin Endocrinol Metab 1985;61:98-103
20. Ikuyama S, Nawata H, Kato K, Ibayashi H, Nagataki H. Plasma growth hormone responses to somatostatin (SRIH) and SRIH receptors in pituitary adenomas in acromegalic patients. J Clin Endocrinol Metab 1986;62:729-33
21. Reubi JC, Landolt AM. The growth hormone responses to octreotide in acromegaly correlate with adenoma somatostatin receptor status. J Clin Endocrinol Metab 1989;68:844-50
22. Patel YC, Greenwood M, Kent G, Panetta R, Srikant CB. Multiple gene transcripts of the somatostatin receptor SSTR2: tissue selective distribution and cAMP regulation. Biochem Biophys Res Commun 1993;192:288-94
23. Yamada M, Monden T, Satoh T, Satoh N, Murakami M, Iriuchijima T, et al. Pituitary adenomas of patients with acromegaly express thyrotropin-releasing hormone receptor messenger RNA: cloning and functional expression of the human thyrotropin-releasing hormone receptor gene. Biochem Biophys Res Commun 1993;195:737-45