Healthy aging: Regulation of the metabolome by cellular redox modulation and prooxidant signaling systems: The essential roles of superoxide anion and hydrogen peroxide

Biogerontology

Volumn 8, Issue 5, 2007, Pages 445-467

  Linnane, Anthony William ^a   Kios, Michael ^a   Vitetta, Luis ^a  

^a EPWORTH HOSPITAL   (Australia)

Author keywords

Cellular bioenergy; Cellular organellar function; Hydrogen peroxide; Metabolome regulation; Mitochondrial DNA; Nitric oxide; Peroxynitrite; Prooxidants, Antioxidants; Proteolysis; Proton motive force; Redox poise modulation; Second messengers; Superoxide anion

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; HYDROGEN PEROXIDE; JANUS KINASE; MITOCHONDRIAL DNA; NITRIC OXIDE; OXIDOREDUCTASE; PEROXYNITRITE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RETINOL; SELENIUM; STAT PROTEIN; SUPEROXIDE; UBIDECARENONE;

AGING; BIOENERGY; BOLUS INJECTION; CANCER; CELL DIFFERENTIATION; CELL METABOLISM; CELL ORGANELLE; CELL PH; CELLULAR DISTRIBUTION; CHIMERA; CLINICAL TRIAL; DIGESTIVE SYSTEM CANCER; DNA DAMAGE; DRUG MEGADOSE; ENZYME ACTIVATION; GENE CONTROL; HUMAN; METABOLIC REGULATION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; SECOND MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; CELL AGING; ENERGY METABOLISM; HUMANS; HYDROGEN PEROXIDE; OXIDANTS; OXIDATION-REDUCTION; SIGNAL TRANSDUCTION; SUPEROXIDES;

EID: 34248199153     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-007-9096-4     Document Type: Review

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