Human aging and global function of coenzyme Q10

Annals of the New York Academy of Sciences

Volumn 959, Issue , 2002, Pages 396-411

  Linnane, Anthony W ^a   Zhang, Chunfang ^a   Yarovaya, Natalia ^a   Kopsidas, George ^a   Kovalenko, Sergey ^a   Papakostopoulos, Penny ^a   Eastwood, Hayden ^a   Graves, Stephen ^b   Richardson, Martin ^a  

^a EPWORTH HOSPITAL   (Australia)

^b ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Coenzyme Q10; Gene expression; Human aging; MtDNA mutations; Skeletal muscle; Vastus lateralis

Indexed keywords

ANTIOXIDANT; MITOCHONDRIAL DNA; UBIQUINONE;

ADULT; AGED; AGING; ANTIOXIDANT ACTIVITY; CELL FUNCTION; CHEMICAL COMPOSITION; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA DAMAGE; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; GENE MUTATION; HUMAN; HUMAN TISSUE; MALE; MITOSIS; RESPIRATORY CHAIN; SKELETAL MUSCLE; VASTUS LATERALIS MUSCLE;

EID: 0036234706     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb02110.x     Document Type: Conference Paper

References (52)

1. Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases
2. Tissue mitochondrial DNA change: A stochastic system
3. 10 supplementation on human skeletal muscle
4. Human skeletal muscle aging; a lifestyle determinant
5. Mitochondrial DNA mutations in aging
6. Tissue-specific distribution of multiple mitochondrial DNA rearrangements during human aging
7. An age-associated correlation between cellular bioenergy decline and extensive mtDNA rearrangements in human skeletal muscle
8. Histochemical and biochemical changes in human skeletal muscle with age in sedentary males age 22-65 years
9. Distribution of different fibre types in human skeletal muscles: Effect of aging studied in whole muscle cross-sections
10. Muscle morphology, enzyme activity, and muscle strength in elderly men and women
11. Adverse changes in fibre type and myosin heavy chain compositions of human jaw muscle vs. limb muscle during ageing
12. What is the cause of the ageing atrophy? Total number, size and proportion of different fibre types studied in whole vastus lateralis muscle from 15- to 83-year old men
13. Respiratory chain failure in adult muscle fibers: Relationship with ageing and possible implications for the neuronal pool
14. Skeletal muscle weakness in old age: Underlying mechanisms
15. Life and death of neurons in the aging brain
16. Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy
17. Cytochrome c oxidase deficient fibers in the limb muscle and diaphragm of man without muscular disease: An age-related alteration
18. Mitochondrial DNA mutation associated with aging and degenerative disease
19. Role of free radical and radiation chemistry
20. Free radical theory of aging: Consequences of mitochondrial aging
21. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
22. Extension of life-span with superoxide dismutase/catalase mimetics
23. The universality of bioenergetic disease and amelioration with redox therapy
24. 10 improves the tolerance of the senescent myocardium to aerobic and ischemic stress: Studies in rats and in human atrial tissue
25. 10 treatment improves the tolerance of the senescent myocardium to pacing stress in the rat
26. 10 in clinical cardiology: A long-term study
27. 10) on muscular dystrophies and neurogenic atrophies
28. Nutritional strategies for treating chronic fatigue syndrome
29. 10 and the regression of metastases
30. Case report: Oral antioxidant therapy for the treatment of primary biliary cirrhosis: A pilot study
31. Energy transformations in the biosynthesis of the immune system: Their relevance to the progression and treatment of AIDS
32. 10 and vitamin B6 for immune responses
33. Peripheral glutamate receptors: Molecular biology and role in taste sensation
34. Studying the structure and regulation of soluble guanylyl cyclase
35. The deactivation of soluble guanylyl cyclase by redox-active agents
36. Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3
37. Antisense TR3 orphan receptor can increase prostate cancer cell viability with etoposide treatment
38. Identification of a human 17p-located cDNA encoding a protein of the Snf2-like helicase family
39. ICAM-1 receptors and cold viruses
40. The Australian Proteome Analysis Facility (APAF): Assembling large scale proteomics through integration and automation
41. Muscle fibre types: How many and what kind?
42. Variability in muscle fibre areas in whole human quadriceps muscle: Effects of increasing age
43. Fibre type composition, structure and cytoskeletal protein location of fibres in anterior tibialis muscle: Comparison between young adults and physically active aged humans
44. Histochemical and enzymatic comparison of the gastrocnemius muscle of young and elderly men and women
45. Photosynthetic control of chloroplast gene expression
46. The iron-sulfur clusters 2 and ubisemiquinone radicals of NADH: Ubiquinone oxidoreductase are involved in energy coupling in submitochondrial particles
47. The existence of a lysosomal redox chain and the role of ubiquinone
48. NADH oxidase activity of rat liver plasma membrane activated by guanine nucleotides
49. Coenzyme Q in Golgi apparatus membrane redox activity and proton uptake
50. Where do the electrons go?
51. Sensing electrons: Protein phosphatase redox regulation
52. Redox state is a central modulator of the balance between self-renewal and differentiation in a dividing glial precursor cell