-
1
-
-
0142087554
-
Antibodies as therapeutic agents: Vive la renaissance!
-
Stockwin LH, Holmes S. Antibodies as therapeutic agents: Vive la renaissance! Exp Opin Biolo Ther 2003;3:1133.
-
(2003)
Exp Opin Biolo Ther
, vol.3
, pp. 1133
-
-
Stockwin, L.H.1
Holmes, S.2
-
2
-
-
30744447697
-
-
Koppe MJ PE, Aarts F, Oyen Wj, et al. Antibody-guided radiation therapy of cancer. Cancer Metast Rev 2005;24:539-67.
-
Koppe MJ PE, Aarts F, Oyen Wj, et al. Antibody-guided radiation therapy of cancer. Cancer Metast Rev 2005;24:539-67.
-
-
-
-
3
-
-
27144550160
-
Arming antibodies: Prospects and challenges for immunoconjugates
-
Wu AM, Senter PD. Arming antibodies: Prospects and challenges for immunoconjugates. Nat Biotechnol 2005;23:1137.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1137
-
-
Wu, A.M.1
Senter, P.D.2
-
5
-
-
2142714017
-
Monoclonal antibodies as therapeutic agents for cancer
-
Harris M. Monoclonal antibodies as therapeutic agents for cancer. Lancet Oncol 2004;5:292.
-
(2004)
Lancet Oncol
, vol.5
, pp. 292
-
-
Harris, M.1
-
6
-
-
0036255688
-
Targeted therapy of cancer with radiolabeled antibodies
-
Goldenberg DM. Targeted therapy of cancer with radiolabeled antibodies. J Nucl Med 2002;43:693.
-
(2002)
J Nucl Med
, vol.43
, pp. 693
-
-
Goldenberg, D.M.1
-
7
-
-
0024444625
-
Tumour radioimmunolocalization in nude mice by use of antiplacental alkaline phosphatase monoclonal antibodies
-
Stigbrand T, Hietala SO, Johansson B, et al. Tumour radioimmunolocalization in nude mice by use of antiplacental alkaline phosphatase monoclonal antibodies. Tumour Biol 1989;10:243.
-
(1989)
Tumour Biol
, vol.10
, pp. 243
-
-
Stigbrand, T.1
Hietala, S.O.2
Johansson, B.3
-
8
-
-
0031858457
-
Monoclonal antibody targeting of ovarian carcinoma
-
Kosmas CK, Hird V, and Epenetos AA. Monoclonal antibody targeting of ovarian carcinoma. Oncology 1998;55:435.
-
(1998)
Oncology
, vol.55
, pp. 435
-
-
Kosmas, C.K.1
Hird, V.2
Epenetos, A.A.3
-
9
-
-
33750612078
-
Recombinant antibodies: From the laboratory to the clinic
-
Albrecht H, DeNardo SJ. Recombinant antibodies: From the laboratory to the clinic. Cancer Biother Radiopharm 2006;21:285.
-
(2006)
Cancer Biother Radiopharm
, vol.21
, pp. 285
-
-
Albrecht, H.1
DeNardo, S.J.2
-
10
-
-
0033791994
-
Designer genes: Recombinant antibody fragments for biological imaging
-
Wu AM, Yazaki PJ: Designer genes: Recombinant antibody fragments for biological imaging. Q J Nucl Med 2000;44:268.
-
(2000)
Q J Nucl Med
, vol.44
, pp. 268
-
-
Wu, A.M.1
Yazaki, P.J.2
-
11
-
-
0027303686
-
Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv
-
Adams GP, McCartney JE, Tai MS, et al. Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv. Cancer Res 1993;53:4026.
-
(1993)
Cancer Res
, vol.53
, pp. 4026
-
-
Adams, G.P.1
McCartney, J.E.2
Tai, M.S.3
-
12
-
-
0029890636
-
Minibody: A novel engineered anticarcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts
-
Hu S, Shively L, Raubitschek A, et al. Minibody: A novel engineered anticarcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts. Cancer Res 1996;56:3055.
-
(1996)
Cancer Res
, vol.56
, pp. 3055
-
-
Hu, S.1
Shively, L.2
Raubitschek, A.3
-
13
-
-
0031036720
-
Redesigned antihuman placental alkaline phosphatase single-chain Fv. Soluble expression, characterization and in vivo tumour targeting
-
Deonarain MP, Rowlinson-Busza G, George AJ, et al. Redesigned antihuman placental alkaline phosphatase single-chain Fv. Soluble expression, characterization and in vivo tumour targeting. Protein Eng 1997;10:89.
-
(1997)
Protein Eng
, vol.10
, pp. 89
-
-
Deonarain, M.P.1
Rowlinson-Busza, G.2
George, A.J.3
-
14
-
-
0036837633
-
Selective targeting of tumoral vasculature: Comparison of different formats of an antibody (L19) to the ED-B domain of fibronectin
-
Borsi L, Balza E, Bestagnb M, et al. Selective targeting of tumoral vasculature: Comparison of different formats of an antibody (L19) to the ED-B domain of fibronectin. Int J Cancer 2002;102:75.
-
(2002)
Int J Cancer
, vol.102
, pp. 75
-
-
Borsi, L.1
Balza, E.2
Bestagnb, M.3
-
15
-
-
0035077938
-
Tumor targeting of radiometal labeled anti-CEA recombinant T84.66 diabody and 184.66 minibody: Comparison to radioiodinated fragments
-
Yazaki PJ, Wu AM, Tsai SW, et al. Tumor targeting of radiometal labeled anti-CEA recombinant T84.66 diabody and 184.66 minibody: Comparison to radioiodinated fragments. Bioconjug Chem 2001;12:220.
-
(2001)
Bioconjug Chem
, vol.12
, pp. 220
-
-
Yazaki, P.J.1
Wu, A.M.2
Tsai, S.W.3
-
16
-
-
1542681650
-
124I-labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific, small-animal PET imaging of xenografts in athymic mice
-
124I-labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific, small-animal PET imaging of xenografts in athymic mice. J Nucl Med 2003;44:1962.
-
(2003)
J Nucl Med
, vol.44
, pp. 1962
-
-
Sundaresan, G.1
Yazaki, P.J.2
Shively, J.E.3
-
17
-
-
4143080306
-
123I-labeled 80-kilodalton engineered anticarcinoembryonic antigen antibody fragment (cT84.66 minibody) in patients with colorectal cancer
-
123I-labeled 80-kilodalton engineered anticarcinoembryonic antigen antibody fragment (cT84.66 minibody) in patients with colorectal cancer. Clin Cancer Res 2004;10:5014.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5014
-
-
Wong, J.Y.1
Chu, D.Z.2
Williams, L.E.3
-
18
-
-
33645071568
-
Avidity-mediated enhancement of in vivo tumor targeting by single-chain Fv dimers
-
Adams GP, Tai MS, McCartney JE, et al. Avidity-mediated enhancement of in vivo tumor targeting by single-chain Fv dimers. Clin Cancer Res 2006;12:1599.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1599
-
-
Adams, G.P.1
Tai, M.S.2
McCartney, J.E.3
-
19
-
-
0029918942
-
Tumor localization of anti-CEA single-chain Fvs: Improved targeting by noncovalent dimers
-
Wu AM, Chen W, Raubitschek A, et al. Tumor localization of anti-CEA single-chain Fvs: Improved targeting by noncovalent dimers. Immunotechnology 1996;2:21.
-
(1996)
Immunotechnology
, vol.2
, pp. 21
-
-
Wu, A.M.1
Chen, W.2
Raubitschek, A.3
-
21
-
-
0023257656
-
Levels of alkaline phosphatase isozymes in human seminoma tissue
-
Hirano KD, Yamamoto UM, Brehmer-Andersson H, et al. Levels of alkaline phosphatase isozymes in human seminoma tissue. Cancer Res 1987;47:2543.
-
(1987)
Cancer Res
, vol.47
, pp. 2543
-
-
Hirano, K.D.1
Yamamoto, U.M.2
Brehmer-Andersson, H.3
-
23
-
-
0038714405
-
Combined low dose radio- and radioimmunotherapy of experimental HeLa Hep 2 tumours
-
Eriksson D, Jomani HM, Sheikholvaezin A, et al. Combined low dose radio- and radioimmunotherapy of experimental HeLa Hep 2 tumours. Eur J Nucl Med Mol Imag 2003;30:895.
-
(2003)
Eur J Nucl Med Mol Imag
, vol.30
, pp. 895
-
-
Eriksson, D.1
Jomani, H.M.2
Sheikholvaezin, A.3
-
24
-
-
0000418676
-
Radioimmunotherapy of HeLa cell tumors in nude mice by a combination of I 131-labeled monoclonal antibodies against placental alkaline phosphatase and cytokeratin
-
Riklund KU, Makiya A, Sundstrom R, et al. Radioimmunotherapy of HeLa cell tumors in nude mice by a combination of I 131-labeled monoclonal antibodies against placental alkaline phosphatase and cytokeratin. Tumor Targ 1995;1:239.
-
(1995)
Tumor Targ
, vol.1
, pp. 239
-
-
Riklund, K.U.1
Makiya, A.2
Sundstrom, R.3
-
25
-
-
33751017388
-
Optimizing the generation of recombinant single-chain antibodies against placental alkaline phosphatase
-
Sheikholvaezin A, Sandström P, Eriksson D, et al. Optimizing the generation of recombinant single-chain antibodies against placental alkaline phosphatase. Hybridoma 2006;25:181.
-
(2006)
Hybridoma
, vol.25
, pp. 181
-
-
Sheikholvaezin, A.1
Sandström, P.2
Eriksson, D.3
-
26
-
-
33947217939
-
Construction and purification of a covalently linked divalent tandem scFv antibody against placental alkaline phosphatase
-
Sheikholvaezin A, Eriksson D, Riklund K, et al. Construction and purification of a covalently linked divalent tandem scFv antibody against placental alkaline phosphatase. Hybridoma 2006;25:255.
-
(2006)
Hybridoma
, vol.25
, pp. 255
-
-
Sheikholvaezin, A.1
Eriksson, D.2
Riklund, K.3
-
27
-
-
84873762502
-
Culture characteristics of four permanent lines of human cancer cells
-
Moore AE, Sabachewsky I, Toolan HW. Culture characteristics of four permanent lines of human cancer cells. Cancer Res 1955;15:598.
-
(1955)
Cancer Res
, vol.15
, pp. 598
-
-
Moore, A.E.1
Sabachewsky, I.2
Toolan, H.W.3
-
28
-
-
0020508096
-
Antigenic determinants of human placental and testicular placental-like alkaline phosphatases as mapped by monoclonal antibodies
-
Millan JL, Stigbrand T. Antigenic determinants of human placental and testicular placental-like alkaline phosphatases as mapped by monoclonal antibodies. Eur J Biochem 1983;136:1.
-
(1983)
Eur J Biochem
, vol.136
, pp. 1
-
-
Millan, J.L.1
Stigbrand, T.2
-
29
-
-
1542698957
-
Cloning immunoglobulin variable domains for expression by the polymerase chain reaction
-
Orlandi R, Gussow DH, Jones PT, et al. Cloning immunoglobulin variable domains for expression by the polymerase chain reaction. Proc Natl Acad Sci U S A 1989;86:3833.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 3833
-
-
Orlandi, R.1
Gussow, D.H.2
Jones, P.T.3
-
30
-
-
0028136310
-
Multimerization behaviour of single-chain Fv variants for the tumour-binding antibody, B72.3
-
Desplancq D, King DJ, Lawson AD, et al. Multimerization behaviour of single-chain Fv variants for the tumour-binding antibody, B72.3. Protein Eng 1994;7:1027.
-
(1994)
Protein Eng
, vol.7
, pp. 1027
-
-
Desplancq, D.1
King, D.J.2
Lawson, A.D.3
-
31
-
-
0030738617
-
New protein engineering approaches to multivalent and bispecific antibody fragments
-
Pluckthun A, Pack P. New protein engineering approaches to multivalent and bispecific antibody fragments. Immunotechnology 1997;3:83.
-
(1997)
Immunotechnology
, vol.3
, pp. 83
-
-
Pluckthun, A.1
Pack, P.2
-
32
-
-
34547383713
-
Preparation of iodine-131 labelled human growth hormone of high specific activity
-
Hunter WM, Greenwood FC. Preparation of iodine-131 labelled human growth hormone of high specific activity. Nature 1962;194:495.
-
(1962)
Nature
, vol.194
, pp. 495
-
-
Hunter, W.M.1
Greenwood, F.C.2
-
33
-
-
0035874887
-
High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules
-
Adams GP, Schier R, McCall AM, et al. High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules. Cancer Res 2001;61:4750.
-
(2001)
Cancer Res
, vol.61
, pp. 4750
-
-
Adams, G.P.1
Schier, R.2
McCall, A.M.3
-
34
-
-
0034037976
-
Experimental radioimmunotherapy
-
Buchsbaum DJ. Experimental radioimmunotherapy. Semin Radiat Oncol 2000;10:156.
-
(2000)
Semin Radiat Oncol
, vol.10
, pp. 156
-
-
Buchsbaum, D.J.1
-
35
-
-
0034803102
-
A review of modifications to recombinant antibodies: Attempt to increase efficacy in oncology applications
-
Reff ME, Heard C. A review of modifications to recombinant antibodies: Attempt to increase efficacy in oncology applications. Crit Rev Oncol Hematol 2001;40:25.
-
(2001)
Crit Rev Oncol Hematol
, vol.40
, pp. 25
-
-
Reff, M.E.1
Heard, C.2
-
36
-
-
0034830739
-
Dimeric and trimeric antibodies: High avidity scFvs for cancer targeting
-
Kortt AA, Dolezal O, Power BE, et al. Dimeric and trimeric antibodies: High avidity scFvs for cancer targeting. Biomol Eng 2001;18:95.
-
(2001)
Biomol Eng
, vol.18
, pp. 95
-
-
Kortt, A.A.1
Dolezal, O.2
Power, B.E.3
-
37
-
-
0026327378
-
Construction, binding properties, metabolism, and tumor targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49
-
Milenic DE, Yokota T, Filpula DR, et al. Construction, binding properties, metabolism, and tumor targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49. Cancer Res 1991;51:6363.
-
(1991)
Cancer Res
, vol.51
, pp. 6363
-
-
Milenic, D.E.1
Yokota, T.2
Filpula, D.R.3
-
38
-
-
0028091566
-
Improved tumor targeting with chemically cross-linked recombinant antibody fragments
-
King DJ, Turner A, Farnsworth AP, et al. Improved tumor targeting with chemically cross-linked recombinant antibody fragments. Cancer Res 1994;54:6176.
-
(1994)
Cancer Res
, vol.54
, pp. 6176
-
-
King, D.J.1
Turner, A.2
Farnsworth, A.P.3
-
39
-
-
0842313257
-
Covalent disulfide-linked anti-CEA diabody allows site-specific conjugation and radiolabeling for tumor targeting applications
-
Olafsen T, Cheung CW, Yazaki PJ, et al. Covalent disulfide-linked anti-CEA diabody allows site-specific conjugation and radiolabeling for tumor targeting applications. Protein Eng Des Sel 2004;17:21.
-
(2004)
Protein Eng Des Sel
, vol.17
, pp. 21
-
-
Olafsen, T.1
Cheung, C.W.2
Yazaki, P.J.3
-
40
-
-
33745727434
-
Mono and bivalent binding of a scFv and covalent diabody to murine laminin-1 using radioiodinated proteins and SPR measurements: Effects on tissue retention in vivo
-
Huang BC, Davern S, Kennel SJ. Mono and bivalent binding of a scFv and covalent diabody to murine laminin-1 using radioiodinated proteins and SPR measurements: Effects on tissue retention in vivo. J Immunol Meth 2006;313:149.
-
(2006)
J Immunol Meth
, vol.313
, pp. 149
-
-
Huang, B.C.1
Davern, S.2
Kennel, S.J.3
-
41
-
-
0037314650
-
Immunoscintigraphic detection of the ED-B domain of fibronectin, a marker of angiogenesis, in patients with cancer
-
Santimaria M, Moscatelli G, Viale GL, et al. Immunoscintigraphic detection of the ED-B domain of fibronectin, a marker of angiogenesis, in patients with cancer. Clin Cancer Res 2003;9:571.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 571
-
-
Santimaria, M.1
Moscatelli, G.2
Viale, G.L.3
-
42
-
-
0033555628
-
Increased binding affinity and valence of recombinant antibody fragments lead to improved targeting of tumoral angiogenesis
-
Viti F, Tarli G, Giovannoni L, et al. Increased binding affinity and valence of recombinant antibody fragments lead to improved targeting of tumoral angiogenesis. Cancer Res 1999;59:347.
-
(1999)
Cancer Res
, vol.59
, pp. 347
-
-
Viti, F.1
Tarli, G.2
Giovannoni, L.3
-
43
-
-
0031942906
-
Prolonged in vivo tumour retention of a human diabody, targeting the extracellular domain of human HER2/neu
-
Adams GP, Schier R, McCall AM, et al. Prolonged in vivo tumour retention of a human diabody, targeting the extracellular domain of human HER2/neu. Br J Cancer 1998;77:1405.
-
(1998)
Br J Cancer
, vol.77
, pp. 1405
-
-
Adams, G.P.1
Schier, R.2
McCall, A.M.3
-
44
-
-
13844310366
-
The in vivo characteristics of genetically engineered divalent and tetravalent single-chain antibody constructs
-
Wittel UA, Jain M, Goel A, et al. The in vivo characteristics of genetically engineered divalent and tetravalent single-chain antibody constructs. Nucl Med Biol 2005;32:157.
-
(2005)
Nucl Med Biol
, vol.32
, pp. 157
-
-
Wittel, U.A.1
Jain, M.2
Goel, A.3
-
45
-
-
0033046339
-
Binding characteristics and tumor targeting of a covalently linked divalent CC49 single-chain antibody
-
Beresford GW, Pavlinkova G, Booth BJ, et al. Binding characteristics and tumor targeting of a covalently linked divalent CC49 single-chain antibody. Int J Cancer 1999;81:911.
-
(1999)
Int J Cancer
, vol.81
, pp. 911
-
-
Beresford, G.W.1
Pavlinkova, G.2
Booth, B.J.3
-
46
-
-
0034074997
-
Divalent forms of CC49 single-chain antibody constructs in Pichia pastoris: Expression, purification, and characterization
-
Goel A, Beresford GW, Colcher D, et al. Divalent forms of CC49 single-chain antibody constructs in Pichia pastoris: Expression, purification, and characterization. J Biochem (Tokyo) 2000;127:829.
-
(2000)
J Biochem (Tokyo)
, vol.127
, pp. 829
-
-
Goel, A.1
Beresford, G.W.2
Colcher, D.3
-
47
-
-
12344254839
-
A diabody that dissociates to monomer forms at low concentration: Effects on binding activity and tumor targeting
-
Huang BC, Foote LJ, Lankford TK, et al. A diabody that dissociates to monomer forms at low concentration: Effects on binding activity and tumor targeting. Biochem Biophys Res Commun 2005;327:999.
-
(2005)
Biochem Biophys Res Commun
, vol.327
, pp. 999
-
-
Huang, B.C.1
Foote, L.J.2
Lankford, T.K.3
|