Arsenite and insulin exhibit opposing effects on epidermal growth factor receptor and keratinocyte proliferative potential

Toxicology and Applied Pharmacology

Volumn 221, Issue 1, 2007, Pages 119-128

  Patterson, Timothy J ^a   Rice, Robert H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

catenin; Antimony; Arsenite; Epidermal growth factor; Insulin; Keratinocyte

Indexed keywords

ARSENIC TRIOXIDE; BETA CATENIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; INSULIN; PROTEIN TYROSINE KINASE; SOMATOMEDIN C RECEPTOR;

ARTICLE; CELL LEVEL; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; KERATINOCYTE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ANTIMONY; ARSENITES; BETA CATENIN; BONE MORPHOGENETIC PROTEINS; CELL LINE, TRANSFORMED; CELL PROLIFERATION; CELLS, CULTURED; CYCLOHEXIMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION; HUMANS; INSULIN; KERATINOCYTES; MALE; MATRIX METALLOPROTEINASE 7; PPAR DELTA; PYRIMIDINES; RAS PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TYRPHOSTINS;

EID: 34247887332     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.02.003     Document Type: Article

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