Ectodomain sheading-dependent transactivation of epidermal growth factor receptors in response to insulin-like growth factor type I

Molecular Endocrinology

Volumn 18, Issue 11, 2004, Pages 2727-2739

  El Shewy, Hesham M ^a,c   Kelly, Francine L ^b   Barki Harrington, Liza ^b   Luttrell, Louis M ^a,c  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; BATIMASTAT; EPIDERMAL GROWTH FACTOR RECEPTOR; GREEN FLUORESCENT PROTEIN; HEPARIN BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; SOMATOMEDIN C; TYROSINE; DRUG DERIVATIVE; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; PHENYLALANINE; PHORBOL 13 ACETATE 12 MYRISTATE; SOMATOMEDIN RECEPTOR; THIOPHENE DERIVATIVE; TYRPHOSTIN;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CELL CULTURE; CELL TYPE; CONTROLLED STUDY; EMBRYO; ENDOCYTOSIS; ENZYME ACTIVATION; ENZYME INHIBITION; FIBROBLAST; HUMAN; HUMAN CELL; KIDNEY CELL; MOUSE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR INTRINSIC ACTIVITY; TRANSACTIVATION; ANIMAL; CELL LINE; CERCOPITHECUS; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RAT;

ANIMALIA; MURINAE;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; ENDOCYTOSIS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; METALLOENDOPEPTIDASES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 3; PARACRINE COMMUNICATION; PHENYLALANINE; PHOSPHORYLATION; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, SOMATOMEDIN; TETRADECANOYLPHORBOL ACETATE; THIOPHENES; TYROSINE; TYRPHOSTINS;

EID: 8344257962     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2004-0174     Document Type: Article

References (53)

1. Medema RH, Bos JL 1993 The role of p21 ras in receptor tyrosine kinase signaling. Crit Rev Oncog 4:615-661
2. White MF 1997 The insulin signalling system and the IRS proteins. Diabetologia 40(Suppl 2):S2-S17
3. Franke TF, Kaplan DR, Cantley LC 1997 PI3K: down-stream AKTion blocks apoptosis. Cell 88:435-437
4. Del Peso L, Gonzalez-Garcia M, Page C, Herrera R, Nunez G 1997 Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 278:687-689
5. Okada T, Kawano Y, Sakakibara T, Hazeki O, Ui M 1994 Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin. J Biol Chem 269:3568-3573
6. Hara K, Yonezawa K, Sakaue H, Ando A, Kotani K, Kitamura T, Kitamura Y, Ueda H, Stephens L, Jackson TR 1994 1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells. Proc Natl Acad Sci USA 91:7415-7419
7. Sasaoka T, Draznin B, Leitner JW, Langlois WJ, Olfesky JM 1994 She is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21 ras-GTP formation. J Biol Chem 269:10734-10738
8. Sasaoka T, Rose DW, Jhun BH, Saltiel AR, Draznin, Olfesky JM 1994 Evidence for a functional role of She proteins in mitogenic signaling induced by insulin, insulin-like growth factor-1, and epidermal growth factor. J Biol Chem 269:13689-13694
9. Boney M, Gruppuso PA, Paris RA, Frackelton Jr AR 2000 The critical role of She in insulin-like growth factor-I-mediated mitogenesis and differentiation in 3T3-L1 preadipocytes. Mol Endocrinol 14:805-813
10. Roudabush FL, Pierce L, Maudsley S, Khan KD, Lin F-T, Luttrell LM 2000 Transactivation of the EGF receptor mediates IGF-1-stimulated she phosphorylation and ERK1/2 activation in COS-7 cells. J Biol Chem 275:22583-22589
11. Luttrell LM, Daaka Y, Lefkowitz RJ 1999 Regulation of tyrosine kinase cascades by G-protein-coupled receptors. Curr Opin Cell Biol 11:177-183
12. Hackel PO, Zwick E, Prenzel N, Ullrich A 1999 Epidermal growth factor receptors: critical mediators of multiple receptor pathways. Curr Opin Cell Biol 11:184-189
13. Carpenter G 1999 Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways. J Cell Biol 146:697-702
14. Yamaguchi T, Ueki K, Tobe K, Tanemoto H, Sekine N, Wada M, Honjo M, Takahashi M, Takahashi T, Harai H, Tushima T, Akanuma Y, Fujita T, Komuro I, Yazaki Y, Kadowaki T 1997 Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone. Nature 390:91-96
15. Moro L, Venturino M, Bozzo C, Silengo L, Altruda F, Beguinot L, Tarone G, Defillippi P 1998 Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival. EMBO J 17:6622-6632
16. Rosen LB, Greenberg ME 1996 Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels. Proc Natl Acad Sci USA 93:1113-1118
17. Zwick E, Daub H, Aoki N, Yamaguchi-Aoki Y, Tinhofer I, MaIy K, Ullrich A1997 Critical role of calcium-dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling. J Biol Chem 272:24767-24770
18. Rosette C, Karin M 1996 Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 274:1194-1197
19. Goldkorn T, Balaban AN, Shannon M, Matsukuma K 1997 EGF receptor phosphorylation is affected by ionizing radiation. Biochim Biophys Acta 1358:289-299
20. Zwick E, Hackel PO, Prenzel N, Ullrich A 1999 The EGF receptor as central transducer of heterologous signalling systems. Trends Pharmacol Sci 20:408-412
21. Gschwind A, Zwick E, Prenzel N, Leserer M, Ullrich A 2001 Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for inter-receptor signal transmission. Oncogene 20:1594-1600
22. Gilmore AP, Valentijn AJ, Wang P, Ranger AM, Bundred N, O'Hare MJ, Wakeling A, Korsmeyer SJ, Streuli CH 2002 Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor. J Biol Chem 277:27643-27650
23. Ahmad T, Farnie G, Bundred NJ, Anderson NG 2004 The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase. J Biol Chem 279:1713-1719
24. Boney CM, Sekimoto H, Gruppuso PA, Frackelton Jr AR 2001 Src family tyrosine kinases participate in insulin-like growth factor I mitogenic signaling in 3T3-L1 cells. Cell Growth Differ 12:379-386
25. Pearson G, Robinson F, Beers Gibson T, Xu BE, Karandikar M, Berman K, Cobb MH 2001 Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev 22:153-183
26. Gechtman Z, Alonso JL, Raab G, Ingber DE, Klagsbrun M 1999 The shedding of membrane-anchored heparin-binding epidermal-like growth factor is regulated by the Raf/mitogen-activated protein kinase cascade and by cell adhesion and spreading. J Biol Chem 274:28828-28835
27. Izumi Y, Hirata M, Hasuwa H, Iwamoto R, Umata T, Miyado K, Tamai Y, Kurisaki T, Sehara-Fujisawa A, Ohno S, Mekada E 1998 A metalloprotease- disintegrin, MDC9/meltrin-γ/ADAM9 and PKCS are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. EMBO J 17:7260-7272
28. Grewal JS, Luttrell LM, Raymond JR 2001 G protein-coupled receptors desensitize and down-regulate epidermal growth factor receptors in renal mesangial cells. J Biol Chem 276:27335-27344
29. Carter RE, Sorkin A 1998 Endocytosis of functional epidermal growth factor receptor-green fluorescent protein chimera. J Biol Chem 273:35000-35007
30. Hunyady L, Baukal AJ, Gaborik Z, Olivares-Reyes JA, Bor M, Szaszak M, Lodge R, Catt KJ, Balla T 2002 Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptor. J Cell Biol 157:1211-1222
31. Sell C, Rubini M, Rubin R, Liu JP, Efstratiadis A, Baserga R 1993 Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor. Proc Natl Acad Sci USA 90:11217-11221
32. DeFea KA, Zalevsky J, Thoma MS, Dery O, Mullins RD, Bunnett NW 2000 β-Arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. J Cell Biol 148:1267-1281
33. Myers Jr MG, Wang LM, Sun X, Zhang Y, Yenush L, Schlessinger J, Pierce JH, White MF 1994 Role of IRS-1-GRB-2 complexes in insulin signaling. Mol Cell Biol 14:3577-3587
34. Nishida K, Hirano T 2003 The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors. Cancer Sci 94:1029-1033
35. Parsons JT 2003 Focal adhesion kinase: the first ten years. J Cell Sci 116:1409-1416
36. Rose DW, Saltiel AR, Majumdar M, Decker SJ, Olefsky JM 1994 Insulin receptor substrate 1 is required for insulin-mediated mitogenic signal transduction. Proc Natl Acad Sci USA 91:797-801
37. Riese DJ II, Stem DF 1998 Specificity within the EGF family/ErbB receptor family signaling network. Bioessays 20:41-48
38. Daub H, Weiss FU, Wallasch C, Ullrich A 1996 Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 379:557-560
39. Eguchi S, Numaguchi K, Iwasaki H, Matsumoto T, Yamakawa T, Utsunomiya H, Motley ED, Kawakatsu H, Owada KM, Hirata Y, Marumo F, Inagami T 1998 Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells. J Biol Chem 273:88960-88968
40. Tsai W, Morielli D, Peralta EG 1997 The m1 muscarinic acetylcholine receptor transactivates the EGF receptor to modulate ion channel activity. EMBO J 16:4597-4605
41. Prenzel N, Zwick E, Daub E, Leserer M, Abraham R, Wallasch C, Ullrich A 1999 EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 402:884-888
42. Pierce KL, Tohgo A, Ahn S, Field ME, Luttrell LM, Lefkowitz RJ 2001 Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding. J Biol Chem 276:23155-23160
43. Ahmed I, Gesty-Palmer D, Drezner MK, Luttrell LM 2003 Transactivation of the epidermal growth factor receptor mediates parathyroid hormone and prostaglandin F2 α-stimulated mitogen-activated protein kinase activation in cultured transgenic murine osteoblasts. Mol Endocrinol 17:1607-1621
44. Goishi K, Higashiyama S, Klagsbrun M, Nakano N, UmataT, Ishikawa M, Mekada E, Taniguchi N 1995 Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity. Mol Biol Cell 6:967-980
45. Dong J, Wiley HS 2000 Trafficking and proteolytic release of epidermal growth factor receptor ligands are modulated by their membrane-anchoring domains. J Biol Chem 275:557-564
46. Dent P, Reardon DB, Park JS, Bowers G, Logsdon C, Valerie K, Schmidt-Ullrich R 1999 Radiation-induced release of transforming growth factor a activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death. Mol Biol Cell 10:2493-2506
47. Fan H, Derynck R 1999 Ectodomain shedding of TGF-α and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades. EMBO J 18:6962-6972
48. Schlondorff J, Blobel CP 1999 Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding. J Cell Sci 112:3603-3617
49. Asakura M, Kitakaze M, Takashima S, Liao Y, Ishikura F, Yoshinaka T, Ohmoto H, Node K, Yoshino K, Ishiguro H, Asanuma H, Sanada S, Matsumura Y, Takeda H, Beppu S, Tada M, Hori M, Higashiyama S 2002 Cardiac hypertrophy is inhibited by antagonism of ADAM 12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy. Nat Med 8:35-40
50. Pietrzkowski Z, Sell C, Lammers R, Ullrich A, Baserga R 1992 Roles of insulin-like growth factor 1 (IGF-1) and the IGF-1 receptor in epidermal growth factor-stimulated growth of 3T3 cells. Mol Cell Biol 12:3883-3889
51. Burgaud JL, Baserga R 1996 Intracellular transactivation of the insulin-like growth factor I receptor by an epidermal growth factor receptor. Exp Cell Res 223:412-419
52. Swantek JL, Baserga R 1999 Prolonged activation of ERK2 by epidermal growth factor and other growth factors requires a functional insulin-like growth factor 1 receptor. Endocrinology 140:3163-3169
53. Kohout TA, Lin FS, Perry SJ, Conner DA, Lefkowitz RJ 2001 β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking. Proc Natl Acad Sci USA 98:1601-1606