Linkage of Graves' disease to the human leucocyte antigen region in the Chinese-Han population in Taiwan

Clinical Endocrinology

Volumn 66, Issue 5, 2007, Pages 646-651

  Chen, Pei Lung ^a,f   Fann, Cathy Shen Jang ^d,e   Chang, Chien Ching ^d   Wu, I Lin ^a   Chiu, Wei Yih ^a   Lin, Chin Yu ^d   Yang, Wei Shiung ^a,b,c,d   Chang, Tien Chun ^a,c  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b Institute of Clinical Medicine   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^e NATIONAL YANG MING UNIVERSITY   (Taiwan)

^f JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER;

ARTICLE; CHINESE; CHROMOSOME 14Q; CHROMOSOME 2Q; CHROMOSOME 5Q; CHROMOSOME 6P; CHROMOSOME 7Q; CONTROLLED STUDY; FAMILIAL DISEASE; FAMILY HISTORY; FEMALE; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENOTYPE; GRAVES DISEASE; HASHIMOTO DISEASE; HLA SYSTEM; HUMAN; HYPOTHYROIDISM; IATROGENIC DISEASE; MAJOR CLINICAL STUDY; MALE; NONPARAMETRIC TEST; PRIORITY JOURNAL; SCORING SYSTEM; SHORT TANDEM REPEAT; SIBLING; TAIWAN;

ASIAN CONTINENTAL ANCESTRY GROUP; CHROMOSOME MAPPING; FEMALE; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GRAVES DISEASE; HUMANS; LINKAGE (GENETICS); LOD SCORE; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MICROSATELLITE REPEATS; TAIWAN;

EID: 34247860724     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2007.02787.x     Document Type: Article

References (48)

1. Weetman, A.P. (2000) Graves' disease. New England Journal of Medicine, 343, 1236 1248.
2. Hollowell, J.G., Staehling, N.W., Flanders, W.D., Hannon, W.H., Gunter, E.W., Spencer, C.A. Braverman, L.E. (2002) Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). Journal of Clinical Endocrinology and Metabolism, 87, 489 499.
3. DeGroot, L.J. Quintans, J. (1989) The causes of autoimmune thyroid disease. Endocrine Reviews, 10, 537 562.
4. Brix, T.H., Kyvik, K.O. Hegedus, L. (1998) What is the evidence of genetic factors in the etiology of Graves' disease? A brief review. Thyroid, 8, 727 734.
5. Vyse, T.J. Todd, J.A. (1996) Genetic analysis of autoimmune disease. Cell, 85, 311 318.
6. Brix, T.H., Kyvik, K.O., Christensen, K. Hegedus, L. (2001) Evidence for a major role of heredity in Graves' disease: a population-based study of two Danish twin cohorts. Journal of Clinical Endocrinology and Metabolism, 86, 930 934.
7. Vaidya, B., Kendall-Taylor, P. Pearce, S.H. (2002) The genetics of autoimmune thyroid disease. Journal of Clinical Endocrinology and Metabolism, 87, 5385 5397.
8. Tomer, Y. Davies, T.F. (2003) Searching for the autoimmune thyroid disease susceptibility genes: from gene mapping to gene function. Endocrine Reviews, 24, 694 717.
9. Ayadi, H., Hadj Kacem, H., Rebai, A. Farid, N.R. (2004) The genetics of autoimmune thyroid disease. Trends in Endocrinology and Metabolism, 15, 234 239.
10. Velaga, M.R., Wilson, V., Jennings, C.E., Owen, C.J., Herington, S., Donaldson, P.T., Ball, S.G., James, R.A., Quinton, R., Perros, P. Pearce, S.H. (2004) The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease. Journal of Clinical Endocrinology and Metabolism, 89, 5862 5865.
11. Yanagawa, T., Mangklabruks, A., Chang, Y.B., Okamoto, Y., Fisfalen, M.E., Curran, P.G. DeGroot, L.J. (1993) Human histocompatibility leukocyte antigen-DQA1*0501 allele associated with genetic susceptibility to Graves' disease in a Caucasian population. Journal of Clinical Endocrinology and Metabolism, 76, 1569 1574.
12. Badenhoop, K., Walfish, P.G., Rau, H., Fischer, S., Nicolay, A., Bogner, U., Schleusener, H. Usadel, K.H. (1995) Susceptibility and resistance alleles of human leukocyte antigen (HLA) DQA1 and HLA DQB1 are shared in endocrine autoimmune disease. Journal of Clinical Endocrinology and Metabolism, 80, 2112 2117.
13. Heward, J.M., Allahabadia, A., Daykin, J., Carr-Smith, J., Daly, A., Armitage, M., Dodson, P.M., Sheppard, M.C., Barnett, A.H., Franklyn, J.A. Gough, S.C. (1998) Linkage disequilibrium between the human leukocyte antigen class II region of the major histocompatibility complex and Graves' disease: replication using a population case control and family-based study. Journal of Clinical Endocrinology and Metabolism, 83, 3394 3397.
14. Huang, S.M., Wu, T.J., Lee, T.D., Yang, E.K., Shaw, C.K. Yeh, C.C. (2003) The association of HLA-A, -B, and -DRB1 genotypes with Graves' disease in Taiwanese people. Tissue Antigens, 61, 154 158.
15. Yeo, P.P., Chan, S.H., Thai, A.C., Ng, W.Y., Lui, K.F., Wee, G.B., Tan, S.H., Lee, B.W., Wong, H.B. Cheah, J.S. (1989) HLA Bw46 and DR9 associations in Graves' disease of Chinese patients are age- and sex-related. Tissue Antigens, 34, 179 184.
16. Onuma, H., Ota, M., Sugenoya, A. Inoko, H. (1994) Association of HLA-DPB1*0501 with early-onset Graves' disease in Japanese. Human Immunology, 39, 195 201.
17. Cho, B.Y., Rhee, B.D., Lee, D.S., Lee, M.S., Kim, G.Y., Lee, H.K., Koh, C.S., Min, H.K. Lee, M. (1987) HLA and Graves' disease in Koreans. Tissue Antigens, 30, 119 121.
18. Wongsurawat, T., Nakkuntod, J., Charoenwongse, P., Snabboon, T., Sridama, V. Hirankarn, N. (2006) The association between HLA class II haplotype with Graves' disease in Thai population. Tissue Antigens, 67, 79 83.
19. Simmonds, M.J., Howson, J.M., Heward, J.M., Cordell, H.J., Foxall, H., Carr-Smith, J., Gibson, S.M., Walker, N., Tomer, Y., Franklyn, J.A., Todd, J.A. Gough, S.C. (2005) Regression mapping of association between the human leukocyte antigen region and Graves' disease. American Journal of Human Genetics, 76, 157 163.
20. Vaidya, B., Imrie, H., Perros, P., Young, E.T., Kelly, W.F., Carr, D., Large, D.M., Toft, A.D., McCarthy, M.I., Kendall-Taylor, P. Pearce, S.H. (1999) The cytotoxic T lymphocyte antigen-4 is a major Graves' disease locus. Human Molecular Genetics, 8, 1195 1199.
21. Tomer, Y., Barbesino, G., Greenberg, D.A., Concepcion, E. Davies, T.F. (1999) Mapping the major susceptibility loci for familial Graves' and Hashimoto's diseases: evidence for genetic heterogeneity and gene interactions. Journal of Clinical Endocrinology and Metabolism, 84, 4656 4664.
22. Sakai, K., Shirasawa, S., Ishikawa, N., Ito, K., Tamai, H., Kuma, K., Akamizu, T., Tanimura, M., Furugaki, K., Yamamoto, K. Sasazuki, T. (2001) Identification of susceptibility loci for autoimmune thyroid disease to 5q31-q33 and Hashimoto's thyroiditis to 8q23-q24 by multipoint affected sib-pair linkage analysis in Japanese. Human Molecular Genetics, 10, 1379 1386.
23. Maalej, A., Makni, H., Ayadi, F., Bellassoued, M., Jouida, J., Bouguacha, N., Abid, M. Ayadi, H. (2001) A full genome screening in a large Tunisian family affected with thyroid autoimmune disorders. Genes and Immunity, 2, 71 75.
24. Jin, Y., Teng, W., Ben, S., Xiong, X., Zhang, J., Xu, S., Shugart, Y.Y., Jin, L., Chen, J. Huang, W. (2003) Genome-wide scan of Graves' disease: evidence for linkage on chromosome 5q31 in Chinese Han pedigrees. Journal of Clinical Endocrinology and Metabolism, 88, 1798 1803.
25. Tomer, Y., Ban, Y., Concepcion, E., Barbesino, G., Villanueva, R., Greenberg, D.A. Davies, T.F. (2003) Common and unique susceptibility loci in Graves and Hashimoto diseases: results of whole-genome screening in a data set of 102 multiplex families. American Journal of Human Genetics, 73, 736 747.
26. Taylor, J.C., Gough, S.C., Hunt, P.J., Brix, T.H., Chatterjee, K., Connell, J.M., Franklyn, J.A., Hegedus, L., Robinson, B.G., Wiersinga, W.M., Wass, J.A., Zabaneh, D., Mackay, I. Weetman, A.P. (2006) A genome-wide screen in 1119 relative pairs with autoimmune thyroid disease. Journal of Clinical Endocrinology and Metabolism, 91, 646 653.
27. Yang, H.C., Lin, C.H., Hsu, C.L., Hung, S.I., Wu, J.Y., Pan, W.H., Chen, Y.T. Fann, C.S. (2006) A comparison of major histocompatibility complex SNPs in Han Chinese residing in Taiwan and Caucasians. Journal of Biomedical Sciences, 13, 489 498.
28. Cao, K., Hollenbach, J., Shi, X., Shi, W., Chopek, M. Fernandez-Vina, M.A. (2001) Analysis of the frequencies of HLA-A, B, and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations. Human Immunology, 62, 1009 1030.
29. Dean, M., Stephens, J.C., Winkler, C., Lomb, D.A., Ramsburg, M., Boaze, R., Stewart, C., Charbonneau, L., Goldman, D. Albaugh, B.J. (1994) Polymorphic admixture typing in human ethnic populations. American Journal of Human Genetics, 55, 788 808.
30. Cao, K., Moormann, A.M., Lyke, K.E., Masaberg, C., Sumba, O.P., Doumbo, O.K., Koech, D., Lancaster, A., Nelson, M., Meyer, D., Single, R., Hartzman, R.J., Plowe, C.V., Kazura, J., Mann, D.L., Sztein, M.B., Thomson, G. Fernandez-Vina, M.A. (2004) Differentiation between African populations is evidenced by the diversity of alleles and haplotypes of HLA class I loci. Tissue Antigens, 63, 293 325.
31. Ghodke, Y., Joshi, K., Chopra, A. Patwardhan, B. (2005) HLA and disease. European Journal of Epidemiology, 20, 475 488.
32. Hadj Kacem, H., Rebai, A., Kaffel, N., Masmoudi, S., Abid, M. Ayadi, H. (2003) PDS is a new susceptibility gene to autoimmune thyroid diseases: association and linkage study. Journal of Clinical Endocrinology and Metabolism, 88, 2274 2280.
33. O'Connell, J.R. Weeks, D.E. (1998) PedCheck: a program for identification of genotype incompatibilities in linkage analysis. American Journal of Human Genetics, 63, 259 266.
34. Abecasis, G.R., Cherny, S.S., Cookson, W.O. Cardon, L.R. (2002) Merlin - rapid analysis of dense genetic maps using sparse gene flow trees. Nature Genetics, 30, 97 101.
35. Kruglyak, L., Daly, M.J., Reeve-Daly, M.P. Lander, E.S. (1996) Parametric and nonparametric linkage analysis: a unified multipoint approach. American Journal of Human Genetics, 58, 1347 1363.
36. Kong, A. Cox, N.J. (1997) Allele-sharing models: LOD scores and accurate linkage tests. American Journal of Human Genetics, 61, 1179 1188.
37. Whittemore, A.S. Halpern, J. (1994) A class of tests for linkage using affected pedigree members. Biometrics, 50, 118 127.
38. Cardon, L.R. Bell, J.I. (2001) Association study designs for complex diseases. Nature Review Genetics, 2, 91 99.
39. Glazier, A.M., Nadeau, J.H. Aitman, T.J. (2002) Finding genes that underlie complex traits. Science, 298, 2345 2349.
40. Armengol, M.P., Juan, M., Lucas-Martin, A., Fernandez-Figueras, M.T., Jaraquemada, D., Gallart, T. Pujol-Borrell, R. (2001) Thyroid autoimmune disease: demonstration of thyroid antigen-specific B cells and recombination-activating gene expression in chemokine-containing active intrathyroidal germinal centers. American Journal of Pathology, 159, 861 873.
41. Lorini, R., Gastaldi, R., Traggiai, C. Perucchin, P.P. (2003) Hashimoto's thyroiditis. Pediatric Endocrinology Reviews, 1 (Suppl. 2 205 211.
42. Weetman, A.P. (2004) Autoimmune thyroid disease. Autoimmunity, 37, 337 340.
43. Miretti, M.M., Walsh, E.C., Ke, X., Delgado, M., Griffiths, M., Hunt, S., Morrison, J., Whittaker, P., Lander, E.S., Cardon, L.R., Bentley, D.R., Rioux, J.D., Beck, S. Deloukas, P. (2005) A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms. American Journal of Human Genetics, 76, 634 646.
44. Simmonds, M.J. Gough, S.C. (2004) Unravelling the genetic complexity of autoimmune thyroid disease: HLA, CTLA-4 and beyond. Clinical and Experimental Immunology, 136, 1 10.
45. Park, M.H., Park, Y.J., Song, E.Y., Park, H., Kim, T.Y., Park, D.J., Park, K.S. Cho, B.Y. (2005) Association of HLA-DR and -DQ genes with Graves' disease in Koreans. Human Immunology, 66, 741 747.
46. Risch, N.J. (2000) Searching for genetic determinants in the new millennium. Nature, 405, 847 856.
47. Wang, W.Y., Barratt, B.J., Clayton, D.G. Todd, J.A. (2005) Genome-wide association studies: theoretical and practical concerns. Nature Review Genetics, 6, 109 118.
48. Altmuller, J., Palmer, L.J., Fischer, G., Scherb, H. Wjst, M. (2001) Genomewide scans of complex human diseases: true linkage is hard to find. American Journal of Human Genetics, 69, 936 950.