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Volumn 73, Issue 4, 2003, Pages 736-747

Common and Unique Susceptibility Loci in Graves and Hashimoto Diseases: Results of Whole-Genome Screening in a Data Set of 102 Multiplex Families

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 10Q; CHROMOSOME 12Q; CHROMOSOME 13Q; CHROMOSOME 14Q; CHROMOSOME 20Q; CHROMOSOME 6P; CHROMOSOME 7Q; CHROMOSOME 8Q; CHROMOSOME XQ; CONTROLLED STUDY; FEMALE; GENE IDENTIFICATION; GENE LOCUS; GENE MAPPING; GENE REPLICATION; GENE SEQUENCE; GENETIC HETEROGENEITY; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENETIC SCREENING; GRAVES DISEASE; HASHIMOTO DISEASE; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE MARKER; PRIORITY JOURNAL;

EID: 0142059659     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/378588     Document Type: Article
Times cited : (189)

References (65)
  • 3
    • 0036064287 scopus 로고    scopus 로고
    • The influence of human leucocyte antigen (HLA) genes on autoimmune thyroid disease (AITD): Results of studies in HLA-DR3 positive AITD families
    • Oxf
    • Ban Y, Davies TF, Greenberg DA, Concepcion ES, Tomer Y (2002) The influence of human leucocyte antigen (HLA) genes on autoimmune thyroid disease (AITD): results of studies in HLA-DR3 positive AITD families. Clin Endocrinol (Oxf) 57:81-88
    • (2002) Clin Endocrinol , vol.57 , pp. 81-88
    • Ban, Y.1    Davies, T.F.2    Greenberg, D.A.3    Concepcion, E.S.4    Tomer, Y.5
  • 4
    • 0002727790 scopus 로고    scopus 로고
    • Linkage analysis of candidate genes in autoimmune thyroid disease: I. Selected immunoregulatory genes
    • Barbesino G, Tomer Y, Concepcion ES, Davies TF, Greenberg DA (1998) Linkage analysis of candidate genes in autoimmune thyroid disease: I. Selected immunoregulatory genes. J Clin Endocrinol Metab 83:1580-1584
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1580-1584
    • Barbesino, G.1    Tomer, Y.2    Concepcion, E.S.3    Davies, T.F.4    Greenberg, D.A.5
  • 5
    • 0015739769 scopus 로고
    • Familial lymphocytic thyroiditis: Analysis of linkage with histocompatibility and blood group
    • Bode HH, Dorf ME, and Forbes AP (1973) Familial lymphocytic thyroiditis: analysis of linkage with histocompatibility and blood group. J Clin Endocrinol Metab 37:692-697
    • (1973) J Clin Endocrinol Metab , vol.37 , pp. 692-697
    • Bode, H.H.1    Dorf, M.E.2    Forbes, A.P.3
  • 6
    • 0035095887 scopus 로고    scopus 로고
    • Evidence for a major role of heredity in Graves' disease: A population-based study of two Danish twin cohorts
    • Brix TH, Kyvik KO, Christensen K, Hegedus L (2001) Evidence for a major role of heredity in Graves' disease: a population-based study of two Danish twin cohorts. J Clin Endocrinol Metab 86:930-934
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 930-934
    • Brix, T.H.1    Kyvik, K.O.2    Christensen, K.3    Hegedus, L.4
  • 7
    • 0034453053 scopus 로고    scopus 로고
    • A population-based study of chronic autoimmune hypothyroidism in Danish twins
    • Brix TH, Kyvik KO, Hegedus L (2000) A population-based study of chronic autoimmune hypothyroidism in Danish twins. J Clin Endocrinol Metab 85:536-539
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 536-539
    • Brix, T.H.1    Kyvik, K.O.2    Hegedus, L.3
  • 8
    • 0020444025 scopus 로고
    • The presence of thyroid autoantibodies in children and adolescents with AITD and in their siblings and parents
    • Burek CL, Huffman WH, Rose NR (1982) The presence of thyroid autoantibodies in children and adolescents with AITD and in their siblings and parents. Clin Immunol Immunopathol 25:395-404
    • (1982) Clin Immunol Immunopathol , vol.25 , pp. 395-404
    • Burek, C.L.1    Huffman, W.H.2    Rose, N.R.3
  • 9
    • 0032928542 scopus 로고    scopus 로고
    • Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans
    • Cox NJ, Frigge M, Nicolae DL, Concannon P, Hanis CL, Bell GI, Kong A (1999) Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans. Nat Genet 21:213-215
    • (1999) Nat Genet , vol.21 , pp. 213-215
    • Cox, N.J.1    Frigge, M.2    Nicolae, D.L.3    Concannon, P.4    Hanis, C.L.5    Bell, G.I.6    Kong, A.7
  • 11
    • 0002982436 scopus 로고    scopus 로고
    • Graves' diseases: Pathogenesis
    • Braverman LE, Utiger RD (eds) Lippincott Williams & Wilkens, Philadelphia
    • Davies TF (2000) Graves' diseases: pathogenesis. In: Braverman LE, Utiger RD (eds) Werner and Ingbar's the thyroid: a fundamental and clinical text, 8th ed. Lippincott Williams & Wilkens, Philadelphia, pp 518-530
    • (2000) Werner and Ingbar's the Thyroid: A Fundamental and Clinical Text, 8th Ed. , pp. 518-530
    • Davies, T.F.1
  • 13
    • 0029845714 scopus 로고    scopus 로고
    • Phenocopies versus genetic heterogeneity: Can we use phenocopy frequencies in linkage analysis to compensate for heterogeneity?
    • Durner M, Greenberg DA, Hodge SE (1996) Phenocopies versus genetic heterogeneity: can we use phenocopy frequencies in linkage analysis to compensate for heterogeneity? Hum Hered 46:265-273
    • (1996) Hum Hered , vol.46 , pp. 265-273
    • Durner, M.1    Greenberg, D.A.2    Hodge, S.E.3
  • 14
    • 0035096682 scopus 로고    scopus 로고
    • Genome scan of idiopathic generalized epilepsy: Evidence for major susceptibility gene and modifying genes influencing the seizure type
    • Durner M, Keddache MA, Tomasini L, Shinnar S, Resor SR, Cohen J, Harden C, et al (2001) Genome scan of idiopathic generalized epilepsy: evidence for major susceptibility gene and modifying genes influencing the seizure type. Ann Neurol 49:328-335
    • (2001) Ann Neurol , vol.49 , pp. 328-335
    • Durner, M.1    Keddache, M.A.2    Tomasini, L.3    Shinnar, S.4    Resor, S.R.5    Cohen, J.6    Harden, C.7
  • 15
    • 0019197036 scopus 로고
    • Graves' disease and HLA: Clinical and epidemiologic associations
    • Oxf
    • Farid NR, Stone E, Johnson G (1980) Graves' disease and HLA: clinical and epidemiologic associations. Clin Endocrinol (Oxf) 13:535-544
    • (1980) Clin Endocrinol , vol.13 , pp. 535-544
    • Farid, N.R.1    Stone, E.2    Johnson, G.3
  • 17
    • 0021083711 scopus 로고
    • Familial distribution of thyroid disease and diabetes: Further evidence for aetiological heterogeneity of diabetes mellitus
    • Gray RS, Elton RA, Clarke BF (1983) Familial distribution of thyroid disease and diabetes: further evidence for aetiological heterogeneity of diabetes mellitus. Q J Med 52:244-255
    • (1983) Q J Med , vol.52 , pp. 244-255
    • Gray, R.S.1    Elton, R.A.2    Clarke, B.F.3
  • 18
    • 0024828416 scopus 로고
    • Inferring mode of inheritance by comparison of LOD scores
    • Greenberg DA (1989) Inferring mode of inheritance by comparison of LOD scores. Am J Med Genet 34:480-486
    • (1989) Am J Med Genet , vol.34 , pp. 480-486
    • Greenberg, D.A.1
  • 19
    • 0032231937 scopus 로고    scopus 로고
    • The power to detect linkage in complex disease by means of simple LOD-score analyses
    • Greenberg DA, Abreu P, Hodge SE (1998) The power to detect linkage in complex disease by means of simple LOD-score analyses. Am J Hum Genet 63:870-879
    • (1998) Am J Hum Genet , vol.63 , pp. 870-879
    • Greenberg, D.A.1    Abreu, P.2    Hodge, S.E.3
  • 20
    • 0015490609 scopus 로고
    • Thyroid antibodies: A study of first degree relatives
    • Hall R, Dingle PR, Roberts DF (1972) Thyroid antibodies: a study of first degree relatives. Clin Genet 3:319-324
    • (1972) Clin Genet , vol.3 , pp. 319-324
    • Hall, R.1    Dingle, P.R.2    Roberts, D.F.3
  • 22
    • 0021998559 scopus 로고
    • Analysis of linkage between HLA haplotype and susceptibility to Graves' disease in multiple-case Chinese families in Hong Kong
    • Copenh
    • Hawkins BR, Ma JT, Lam KS, Wang CC, Yeung RT (1985) Analysis of linkage between HLA haplotype and susceptibility to Graves' disease in multiple-case Chinese families in Hong Kong. Acta Endocrinol (Copenh) 110:66-69
    • (1985) Acta Endocrinol , vol.110 , pp. 66-69
    • Hawkins, B.R.1    Ma, J.T.2    Lam, K.S.3    Wang, C.C.4    Yeung, R.T.5
  • 23
    • 0031019267 scopus 로고    scopus 로고
    • Magnitude of type I error when single-locus linkage analysis is maximized over models: A simulation study
    • Hodge SE, Abreu PC, Greenberg DA (1997) Magnitude of type I error when single-locus linkage analysis is maximized over models: a simulation study. Am J Hum Genet 60:217-227
    • (1997) Am J Hum Genet , vol.60 , pp. 217-227
    • Hodge, S.E.1    Abreu, P.C.2    Greenberg, D.A.3
  • 24
    • 0036173697 scopus 로고    scopus 로고
    • Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)
    • Hollowell JG, Staehling NW, Flanders WD, Hannon WH, Gunter EW, Spencer CA, Braverman LE (2002) Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab 87:489-499
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 489-499
    • Hollowell, J.G.1    Staehling, N.W.2    Flanders, W.D.3    Hannon, W.H.4    Gunter, E.W.5    Spencer, C.A.6    Braverman, L.E.7
  • 26
    • 0031240055 scopus 로고    scopus 로고
    • Epidemiology and estimated population burden of selected autoimmune diseases in the United States
    • Jacobson DL, Gange SJ, Rose NR, Graham NM (1997) Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clin Immunol Immunopathol 84:223-243
    • (1997) Clin Immunol Immunopathol , vol.84 , pp. 223-243
    • Jacobson, D.L.1    Gange, S.J.2    Rose, N.R.3    Graham, N.M.4
  • 28
    • 0029886532 scopus 로고    scopus 로고
    • Parametric and nonparametric linkage analysis: A unified multipoint approach
    • Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES (1996) Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet 58:1347-1363
    • (1996) Am J Hum Genet , vol.58 , pp. 1347-1363
    • Kruglyak, L.1    Daly, M.J.2    Reeve-Daly, M.P.3    Lander, E.S.4
  • 29
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • Lander E, Kruglyak L (1995) Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 11:241-247
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 30
    • 0029147665 scopus 로고
    • Affected sibpair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-27
    • Luo DF, Bui MM, Muir A, Maclaren NK, Thomson G, She JX (1995) Affected sibpair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-27. Am J Hum Genet 57:911-919
    • (1995) Am J Hum Genet , vol.57 , pp. 911-919
    • Luo, D.F.1    Bui, M.M.2    Muir, A.3    Maclaren, N.K.4    Thomson, G.5    She, J.X.6
  • 33
    • 0023571592 scopus 로고
    • Prevalence of thyroid disease and abnormal thyroid function test results in patients with systemic lupus erythematosus
    • Miller FW, Moore GF, Weintraub BD, Steinberg AD (1987) Prevalence of thyroid disease and abnormal thyroid function test results in patients with systemic lupus erythematosus. Arthritis Rheum 30:1124-1131
    • (1987) Arthritis Rheum , vol.30 , pp. 1124-1131
    • Miller, F.W.1    Moore, G.F.2    Weintraub, B.D.3    Steinberg, A.D.4
  • 34
    • 77049298733 scopus 로고
    • The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type
    • Morton NE (1956) The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type. Am J Hum Genet 8:80-96
    • (1956) Am J Hum Genet , vol.8 , pp. 80-96
    • Morton, N.E.1
  • 35
    • 0017192186 scopus 로고
    • A computer program for linkage analysis of general human pedigrees
    • Ott J (1976) A computer program for linkage analysis of general human pedigrees. Am J Hum Genet 28:528-529
    • (1976) Am J Hum Genet , vol.28 , pp. 528-529
    • Ott, J.1
  • 36
    • 0030023292 scopus 로고    scopus 로고
    • Complex traits on the map
    • _ (1996) Complex traits on the map. Nature 379:772-773
    • (1996) Nature , vol.379 , pp. 772-773
  • 38
    • 0036440770 scopus 로고    scopus 로고
    • Evaluating genetic heterogeneity in complex disorders
    • Pal DK, Greenberg DA (2002) Evaluating genetic heterogeneity in complex disorders. Hum Hered 53:216-226
    • (2002) Hum Hered , vol.53 , pp. 216-226
    • Pal, D.K.1    Greenberg, D.A.2
  • 41
    • 0035875097 scopus 로고    scopus 로고
    • Identification of susceptibility loci for autoimmune thyroid disease to 5q31-q33 and Hashimoto's thyroiditis to 8q23-q24 by multipoint affected sib-pair linkage analysis in Japanese
    • Sakai K, Shirasawa S, Ishikawa N, Ito K, Tamai H, Kuma K, Akamizu T, Tanimura M, Furugaki K, Yamamoto K, Sasazuki T (2001) Identification of susceptibility loci for autoimmune thyroid disease to 5q31-q33 and Hashimoto's thyroiditis to 8q23-q24 by multipoint affected sib-pair linkage analysis in Japanese. Hum Mol Genet 10:1379-1386
    • (2001) Hum Mol Genet , vol.10 , pp. 1379-1386
    • Sakai, K.1    Shirasawa, S.2    Ishikawa, N.3    Ito, K.4    Tamai, H.5    Kuma, K.6    Akamizu, T.7    Tanimura, M.8    Furugaki, K.9    Yamamoto, K.10    Sasazuki, T.11
  • 43
    • 0027989666 scopus 로고
    • Combined segregation and linkage analysis of Graves' disease with a thyroid autoantibody diathesis
    • Shields DC, Ratanachaiyavong S, McGregor AM, Collins A, Morton NE (1994) Combined segregation and linkage analysis of Graves' disease with a thyroid autoantibody diathesis. Am J Hum Genet 55:540-554
    • (1994) Am J Hum Genet , vol.55 , pp. 540-554
    • Shields, D.C.1    Ratanachaiyavong, S.2    McGregor, A.M.3    Collins, A.4    Morton, N.E.5
  • 46
    • 0033304849 scopus 로고    scopus 로고
    • Mapping the major susceptibility loci for familial Graves' and Hashimoto's diseases: Evidence for genetic heterogeneity and gene interactions
    • _ (1999) Mapping the major susceptibility loci for familial Graves' and Hashimoto's diseases: evidence for genetic heterogeneity and gene interactions. J Clin Endocrinol Metab 84:4656-4664
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 4656-4664
  • 48
    • 0142100840 scopus 로고    scopus 로고
    • The genetics of the autoimmune thyroid diseases
    • Baxter JD, Melmed S, New MI (eds) . Lippincot Williams and Wilkins, Philadelphia
    • _ (2002a) The genetics of the autoimmune thyroid diseases. In: Baxter JD, Melmed S, New MI (eds) Genetics in Endocrinology. Lippincot Williams and Wilkins, Philadelphia, pp 137-152
    • (2002) Genetics in Endocrinology , pp. 137-152
  • 49
    • 0036959340 scopus 로고    scopus 로고
    • A C/T single nucleotide polymorphism in the region of the CD40 gene is associated with Graves' disease
    • Tomer Y, Concepcion E, Greenberg DA (2002b) A C/T single nucleotide polymorphism in the region of the CD40 gene is associated with Graves' disease. Thyroid 12:1129-1135
    • (2002) Thyroid , vol.12 , pp. 1129-1135
    • Tomer, Y.1    Concepcion, E.2    Greenberg, D.A.3
  • 50
    • 0027510452 scopus 로고
    • Infection, thyroid disease and autoimmunity
    • Tomer Y, Davies TF (1993) Infection, thyroid disease and autoimmunity. Endocr Rev 14:107-120
    • (1993) Endocr Rev , vol.14 , pp. 107-120
    • Tomer, Y.1    Davies, T.F.2
  • 57
    • 0035089255 scopus 로고    scopus 로고
    • Power to detect linkage based on multiple sets of data in the presence of locus heterogeneity: Comparative evaluation of model-based linkage methods for affected sib pair data
    • Vieland VJ, Wang K, Huang J (2001) Power to detect linkage based on multiple sets of data in the presence of locus heterogeneity: comparative evaluation of model-based linkage methods for affected sib pair data. Hum Hered 51:199-208
    • (2001) Hum Hered , vol.51 , pp. 199-208
    • Vieland, V.J.1    Wang, K.2    Huang, J.3
  • 58
    • 0033774894 scopus 로고    scopus 로고
    • Limited genetic susceptibility to severe Graves' ophthalmopathy: No role for CTLA-4 and evidence for an environmental etiology
    • Villanueva RB, Inzerillo AM, Tomer Y, Barbesino G, Meltzer M, Concepcion ES, Greenberg DA, et al (2000) Limited genetic susceptibility to severe Graves' ophthalmopathy: no role for CTLA-4 and evidence for an environmental etiology. Thyroid 10:791-798
    • (2000) Thyroid , vol.10 , pp. 791-798
    • Villanueva, R.B.1    Inzerillo, A.M.2    Tomer, Y.3    Barbesino, G.4    Meltzer, M.5    Concepcion, E.S.6    Greenberg, D.A.7
  • 59
    • 0001873665 scopus 로고
    • Autoimmune thyroid disease
    • Volpe R (ed) . Marcel Dekker, New York
    • Volpe R (1985) Autoimmune thyroid disease. In: Volpe R (ed) Autoimmunity and endocrine disease. Marcel Dekker, New York, pp 109-285
    • (1985) Autoimmunity and Endocrine Disease , pp. 109-285
    • Volpe, R.1
  • 60
    • 0031157347 scopus 로고    scopus 로고
    • Control of multiple autoantibodies linked with a lupus nephritis susceptibility locus in New Zealand black mice
    • Vyse TJ, Rozzo SJ, Drake CG, Izui S, Kotzin BL (1997) Control of multiple autoantibodies linked with a lupus nephritis susceptibility locus in New Zealand black mice. J Immunol 158: 5566-5574
    • (1997) J Immunol , vol.158 , pp. 5566-5574
    • Vyse, T.J.1    Rozzo, S.J.2    Drake, C.G.3    Izui, S.4    Kotzin, B.L.5
  • 61
    • 0029982537 scopus 로고    scopus 로고
    • Genetic analysis of autoimmune disease
    • Vyse TJ, Todd JA (1996) Genetic analysis of autoimmune disease. Cell 85:311-318
    • (1996) Cell , vol.85 , pp. 311-318
    • Vyse, T.J.1    Todd, J.A.2
  • 62
    • 0002093905 scopus 로고    scopus 로고
    • Chronic autoimmune thyroiditis
    • Braverman LE, Utiger RD (eds) . Lippincott-Raven, Philadelphia
    • Weetman AP (1996) Chronic autoimmune thyroiditis. In: Braverman LE, Utiger RD (eds) Werner and Ingbar's the thyroid. Lippincott-Raven, Philadelphia, pp 738-748
    • (1996) Werner and Ingbar's the Thyroid , pp. 738-748
    • Weetman, A.P.1
  • 63
    • 0023635105 scopus 로고
    • The association of autoimmune thyroiditis with systemic lupus erythematosus
    • Weetman AP, Walport MJ (1987) The association of autoimmune thyroiditis with systemic lupus erythematosus. Br J Rheumatol 26:359-361
    • (1987) Br J Rheumatol , vol.26 , pp. 359-361
    • Weetman, A.P.1    Walport, M.J.2


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