메뉴 건너뛰기




Volumn 17, Issue 3, 2007, Pages 169-180

The discovery of new coding alleles of human CYP26A1 that are potentially defective in the metabolism of all-trans retinoic acid and their assessment in a recombinant cDNA expression system

Author keywords

CYP26A1; P450; Polymorphisms; Retinoic acid; Retinoic acid metabolism

Indexed keywords

4 HYDROXYRETINOIC ACID; 4 OXORETINOIC ACID; COMPLEMENTARY DNA; CYP26A1 PROTEIN; CYTOCHROME P450; GENE PRODUCT; RETINOIC ACID; UNCLASSIFIED DRUG;

EID: 34247563336     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e32801152d6     Document Type: Article
Times cited : (22)

References (47)
  • 1
    • 0036578794 scopus 로고    scopus 로고
    • Retinoid metabolism: A balancing act
    • Perlmann T. Retinoid metabolism: a balancing act. Nat Genet 2002; 31:7-8.
    • (2002) Nat Genet , vol.31 , pp. 7-8
    • Perlmann, T.1
  • 2
    • 0036029643 scopus 로고    scopus 로고
    • The role of vitamin A in mammalian reproduction and embryonic development
    • Clagett-Dame M, DeLuca HF. The role of vitamin A in mammalian reproduction and embryonic development. Annu Rev Nutr 2002; 22:347-381.
    • (2002) Annu Rev Nutr , vol.22 , pp. 347-381
    • Clagett-Dame, M.1    DeLuca, H.F.2
  • 3
    • 24044526526 scopus 로고    scopus 로고
    • Retinoic acid and retinoid receptors: Potential chemopreventive and therapeutic role in cervical cancer
    • Abu J, Batuwangala M, Herbert K, Symonds P. Retinoic acid and retinoid receptors: potential chemopreventive and therapeutic role in cervical cancer. Lancet Oncol 2005; 6:712-720.
    • (2005) Lancet Oncol , vol.6 , pp. 712-720
    • Abu, J.1    Batuwangala, M.2    Herbert, K.3    Symonds, P.4
  • 4
    • 0028920237 scopus 로고
    • Endogenous distribution of retinoids during normal development and teratogenesis in the mouse embryo
    • Horton C, Maden M. Endogenous distribution of retinoids during normal development and teratogenesis in the mouse embryo. Dev Dyn 1995; 202:312-323.
    • (1995) Dev Dyn , vol.202 , pp. 312-323
    • Horton, C.1    Maden, M.2
  • 5
    • 0036578757 scopus 로고    scopus 로고
    • Genetic evidence that oxidative derivatives of retinoic acid are not involved in retinoid signaling during mouse development
    • Niederreither K, Abu-Abed S, Schuhbaur B, Petkovich M, Chambon P, Dolle P. Genetic evidence that oxidative derivatives of retinoic acid are not involved in retinoid signaling during mouse development. Nat Genet 2002; 31:84-88.
    • (2002) Nat Genet , vol.31 , pp. 84-88
    • Niederreither, K.1    Abu-Abed, S.2    Schuhbaur, B.3    Petkovich, M.4    Chambon, P.5    Dolle, P.6
  • 6
    • 0029861003 scopus 로고    scopus 로고
    • Identification of the retinoic acid-inducible all-trans-retinoic acid 4-hydroxylase
    • White JA, Guo YD, Baetz K, Beckett-Jones B, Bonasoro J, Hsu KE, et al. Identification of the retinoic acid-inducible all-trans-retinoic acid 4-hydroxylase. J Biol Chem 1996; 271:29922-29927.
    • (1996) J Biol Chem , vol.271 , pp. 29922-29927
    • White, J.A.1    Guo, Y.D.2    Baetz, K.3    Beckett-Jones, B.4    Bonasoro, J.5    Hsu, K.E.6
  • 7
    • 0030872361 scopus 로고    scopus 로고
    • Metabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos
    • Fujii H, Sato T, Kaneko S, Gotoh O, Fujii-Kuriyama Y, Osawa K, et al. Metabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos. EMBO J 1997; 16:4163-4173.
    • (1997) EMBO J , vol.16 , pp. 4163-4173
    • Fujii, H.1    Sato, T.2    Kaneko, S.3    Gotoh, O.4    Fujii-Kuriyama, Y.5    Osawa, K.6
  • 8
    • 0034612252 scopus 로고    scopus 로고
    • Identification of the human cytochrome P450, P450RAI-2, which is predominantly expressed in the adult cerebellum and is responsible for all-trans-retinoic acid metabolism
    • White JA, Ramshaw H, Taimi M, Stangle W, Zhang A, Everingham S, et al. Identification of the human cytochrome P450, P450RAI-2, which is predominantly expressed in the adult cerebellum and is responsible for all-trans-retinoic acid metabolism. Proc Natl Acad Sci U S A 2000; 97:6403-6408.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 6403-6408
    • White, J.A.1    Ramshaw, H.2    Taimi, M.3    Stangle, W.4    Zhang, A.5    Everingham, S.6
  • 9
    • 0029794132 scopus 로고    scopus 로고
    • A decade of molecular biology of retinoic acid receptors
    • Chambon P. A decade of molecular biology of retinoic acid receptors. FASEB J 1996; 10:940-954.
    • (1996) FASEB J , vol.10 , pp. 940-954
    • Chambon, P.1
  • 10
    • 0027364831 scopus 로고
    • Expression of cellular retinoic acid-binding protein (type II) in Escherichia coli. Characterization and comparison to cellular retinoic acid-binding protein (type I)
    • Fiorella PD, Giguere V, Napoli JL. Expression of cellular retinoic acid-binding protein (type II) in Escherichia coli. Characterization and comparison to cellular retinoic acid-binding protein (type I). J Biol Chem 1993; 268:21545-21552.
    • (1993) J Biol Chem , vol.268 , pp. 21545-21552
    • Fiorella, P.D.1    Giguere, V.2    Napoli, J.L.3
  • 12
    • 0035862977 scopus 로고    scopus 로고
    • The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures
    • Abu-Abed S, Dolle P, Metzger D, Beckett B, Chambon P, Petkovich M. The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures. Genes Dev 2001; 15:226-240.
    • (2001) Genes Dev , vol.15 , pp. 226-240
    • Abu-Abed, S.1    Dolle, P.2    Metzger, D.3    Beckett, B.4    Chambon, P.5    Petkovich, M.6
  • 13
    • 0033863834 scopus 로고    scopus 로고
    • Induction of the cytochrome P450 gene CYP26 during mucous cell differentiation of normal human tracheobronchial epithelial cells
    • Kim SY, Adachi H, Koo JS, Jetten AM. Induction of the cytochrome P450 gene CYP26 during mucous cell differentiation of normal human tracheobronchial epithelial cells. Mol Pharmacol 2000; 58:483-490.
    • (2000) Mol Pharmacol , vol.58 , pp. 483-490
    • Kim, S.Y.1    Adachi, H.2    Koo, J.S.3    Jetten, A.M.4
  • 14
    • 0032429154 scopus 로고    scopus 로고
    • A DNA polymorphism discovery resource for research on human genetic variation
    • Collins FS, Brooks LD, Chakravarti A. A DNA polymorphism discovery resource for research on human genetic variation. Genome Res 1998; 8:1229-1231.
    • (1998) Genome Res , vol.8 , pp. 1229-1231
    • Collins, F.S.1    Brooks, L.D.2    Chakravarti, A.3
  • 15
    • 0025994649 scopus 로고
    • Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli
    • Barnes HJ, Arlotto MP, Waterman MR. Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli. Proc Natl Acad Sci U S A 1991; 88:5597-5601.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 5597-5601
    • Barnes, H.J.1    Arlotto, M.P.2    Waterman, M.R.3
  • 16
    • 15744390776 scopus 로고    scopus 로고
    • Recombinant CYP3A4*17 is defective in metabolizing the hypertensive drug nifedipine, and the CYP3A4*17 allele may occur on the same chromosome as CYP3A5*3, representing a new putative defective CYP3A haplotype
    • Lee SJ, Bell DA, Coulter SJ, Ghanayem B, Goldstein JA. Recombinant CYP3A4*17 is defective in metabolizing the hypertensive drug nifedipine, and the CYP3A4*17 allele may occur on the same chromosome as CYP3A5*3, representing a new putative defective CYP3A haplotype. J Pharmacol Exp Ther 2005; 313:302-309.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 302-309
    • Lee, S.J.1    Bell, D.A.2    Coulter, S.J.3    Ghanayem, B.4    Goldstein, J.A.5
  • 17
    • 0041881985 scopus 로고    scopus 로고
    • Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups
    • Lee SJ, Usmani KA, Chanas B, Ghanayem B, Xi T, Hodgson E, et al. Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups. Pharmacogenetics 2003; 13:461-472.
    • (2003) Pharmacogenetics , vol.13 , pp. 461-472
    • Lee, S.J.1    Usmani, K.A.2    Chanas, B.3    Ghanayem, B.4    Xi, T.5    Hodgson, E.6
  • 18
    • 0033674630 scopus 로고    scopus 로고
    • Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites
    • Marill J, Cresteil T, Lanotte M, Chabot GG. Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites. Mol Pharmacol 2000; 58:1341-1348.
    • (2000) Mol Pharmacol , vol.58 , pp. 1341-1348
    • Marill, J.1    Cresteil, T.2    Lanotte, M.3    Chabot, G.G.4
  • 19
    • 0033970047 scopus 로고    scopus 로고
    • Mammalian microsomal cytochrome P450 monooxygenase: Structural adaptations for membrane binding and functional diversity
    • Williams PA, Cosme J, Sridhar V, Johnson EF, McRee DE. Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity. Mol Cell 2000; 5:121-131.
    • (2000) Mol Cell , vol.5 , pp. 121-131
    • Williams, P.A.1    Cosme, J.2    Sridhar, V.3    Johnson, E.F.4    McRee, D.E.5
  • 20
    • 1542364450 scopus 로고    scopus 로고
    • Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site
    • Schoch GA, Yano JK, Wester MR, Griffin KJ, Stout CD, Johnson EF. Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site. J Biol Chem 2004; 279:9497-9503.
    • (2004) J Biol Chem , vol.279 , pp. 9497-9503
    • Schoch, G.A.1    Yano, J.K.2    Wester, M.R.3    Griffin, K.J.4    Stout, C.D.5    Johnson, E.F.6
  • 22
    • 4644301430 scopus 로고    scopus 로고
    • The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution
    • Yano JK, Wester MR, Schoch GA, Griffin KJ, Stout CD, Johnson EF. The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution. J Biol Chem 2004; 279:38091-38094.
    • (2004) J Biol Chem , vol.279 , pp. 38091-38094
    • Yano, J.K.1    Wester, M.R.2    Schoch, G.A.3    Griffin, K.J.4    Stout, C.D.5    Johnson, E.F.6
  • 23
    • 0031612929 scopus 로고    scopus 로고
    • Recommendations for a nomenclature system for human gene mutations. Nomenclature Working Group
    • Antonarakis SE. Recommendations for a nomenclature system for human gene mutations. Nomenclature Working Group. Hum Mutat 1998; 11:1-3.
    • (1998) Hum Mutat , vol.11 , pp. 1-3
    • Antonarakis, S.E.1
  • 24
    • 0033743405 scopus 로고    scopus 로고
    • Cytochrome P450RAI(CYP26) promoter: A distinct composite retinoic acid response element underlies the complex regulation of retinoic acid metabolism
    • Loudig O, Babichuk C, White J, Abu-Abed S, Mueller C, Petkovich M. Cytochrome P450RAI(CYP26) promoter: a distinct composite retinoic acid response element underlies the complex regulation of retinoic acid metabolism. Mol Endocrinol 2000; 14:1483-1497.
    • (2000) Mol Endocrinol , vol.14 , pp. 1483-1497
    • Loudig, O.1    Babichuk, C.2    White, J.3    Abu-Abed, S.4    Mueller, C.5    Petkovich, M.6
  • 25
    • 0347683479 scopus 로고    scopus 로고
    • A novel human cytochrome P450, CYP26C1, involved in metabolism of 9-cis and all-trans isomers of retinoic acid
    • Taimi M, Helvig C, Wisniewski J, Ramshaw H, White J, Amad M, et al. A novel human cytochrome P450, CYP26C1, involved in metabolism of 9-cis and all-trans isomers of retinoic acid. J Biol Chem 2004; 279:77-85.
    • (2004) J Biol Chem , vol.279 , pp. 77-85
    • Taimi, M.1    Helvig, C.2    Wisniewski, J.3    Ramshaw, H.4    White, J.5    Amad, M.6
  • 26
    • 0030746211 scopus 로고    scopus 로고
    • cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450
    • White JA, Beckett-Jones B, Guo YD, Dilworth FJ, Bonasoro J, Jones G, Petkovich M. cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450. J Biol Chem 1997; 272:18538-18541.
    • (1997) J Biol Chem , vol.272 , pp. 18538-18541
    • White, J.A.1    Beckett-Jones, B.2    Guo, Y.D.3    Dilworth, F.J.4    Bonasoro, J.5    Jones, G.6    Petkovich, M.7
  • 27
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: Translating functional genomics into rational therapeutics
    • Evans WE, Relling MV. Pharmacogenomics: translating functional genomics into rational therapeutics. Science 1999; 286:487-491.
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 28
    • 0035775486 scopus 로고    scopus 로고
    • Pharmacogenomics: The inherited basis for interindividual differences in drug response
    • Evans WE, Johnson JA. Pharmacogenomics: the inherited basis for interindividual differences in drug response. Annu Rev Genomics Hum Genet 2001; 2:9-39.
    • (2001) Annu Rev Genomics Hum Genet , vol.2 , pp. 9-39
    • Evans, W.E.1    Johnson, J.A.2
  • 29
    • 0035862976 scopus 로고    scopus 로고
    • The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo
    • Sakai Y, Meno C, Fujii H, Nishino J, Shiratori H, Saijoh Y, et al. The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo. Genes Dev 2001; 15:213-225.
    • (2001) Genes Dev , vol.15 , pp. 213-225
    • Sakai, Y.1    Meno, C.2    Fujii, H.3    Nishino, J.4    Shiratori, H.5    Saijoh, Y.6
  • 30
    • 0025941823 scopus 로고
    • Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid
    • Kessel M, Gruss P. Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid. Cell 1991; 67:89-104.
    • (1991) Cell , vol.67 , pp. 89-104
    • Kessel, M.1    Gruss, P.2
  • 34
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson JD, Higgins DG, Gibson TJ. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 1994; 22:4673-4680.
    • (1994) Nucleic Acids Res , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 35
    • 0034623005 scopus 로고    scopus 로고
    • T-Coffee: A novel method for fast and accurate multiple sequence alignment
    • Notredame C, Higgins DG, Heringa J. T-Coffee: a novel method for fast and accurate multiple sequence alignment. J Mol Biol 2000; 302:205-217.
    • (2000) J Mol Biol , vol.302 , pp. 205-217
    • Notredame, C.1    Higgins, D.G.2    Heringa, J.3
  • 38
    • 23844466995 scopus 로고    scopus 로고
    • Flavocytochrome P450 BM3: An update on structure and mechanism of a biotechnologically important enzyme
    • Warman AJ, Roitel O, Neeli R, Girvan HM, Seward HE, Murray SA, et al. Flavocytochrome P450 BM3: an update on structure and mechanism of a biotechnologically important enzyme. Biochem Soc Trans 2005; 33(Pt 4):747-753.
    • (2005) Biochem Soc Trans , vol.33 , Issue.PART 4 , pp. 747-753
    • Warman, A.J.1    Roitel, O.2    Neeli, R.3    Girvan, H.M.4    Seward, H.E.5    Murray, S.A.6
  • 39
    • 4644240992 scopus 로고    scopus 로고
    • Identification of the fenretinide metabolite 4-oxo-fenretinide present in human plasma and formed in human ovarian carcinoma cells through induction of cytochrome P450 26A1
    • Villani MG, Appierto V, Cavadini E, Valsecchi M, Sonnino S, Curley RW, Formelli F. Identification of the fenretinide metabolite 4-oxo-fenretinide present in human plasma and formed in human ovarian carcinoma cells through induction of cytochrome P450 26A1. Clin Cancer Res 2004; 10(18 Pt 1):6265-6275.
    • (2004) Clin Cancer Res , vol.10 , Issue.18 PART 1 , pp. 6265-6275
    • Villani, M.G.1    Appierto, V.2    Cavadini, E.3    Valsecchi, M.4    Sonnino, S.5    Curley, R.W.6    Formelli, F.7
  • 40
    • 19344361824 scopus 로고    scopus 로고
    • Regulation of CYP26A1 expression by selective RAR and RXR agonists in human NB4 promyelocytic leukemia cells
    • Idres N, Marill J, Chabot GG. Regulation of CYP26A1 expression by selective RAR and RXR agonists in human NB4 promyelocytic leukemia cells. Biochem Pharmacol 2005; 69:1595-1601.
    • (2005) Biochem Pharmacol , vol.69 , pp. 1595-1601
    • Idres, N.1    Marill, J.2    Chabot, G.G.3
  • 41
    • 0036240012 scopus 로고    scopus 로고
    • Ozpolat B, Mehta K, Tari AM, Lopez-Berestein G. All-trans-retinoic acidinduced expression and regulation of retinoic acid 4-hydroxylase (CYP26) in human promyelocytic leukemia. Am J Hematol 2002; 70:39-47.
    • Ozpolat B, Mehta K, Tari AM, Lopez-Berestein G. All-trans-retinoic acidinduced expression and regulation of retinoic acid 4-hydroxylase (CYP26) in human promyelocytic leukemia. Am J Hematol 2002; 70:39-47.
  • 42
    • 26944460025 scopus 로고    scopus 로고
    • Regulation of a highly specific retinoic acid-4-hydroxylase (CYP26A1) enzyme and all-trans-retinoic acid metabolism in human intestinal, liver, endothelial, and acute promyelocytic leukemia cells
    • Ozpolat B, Mehta K, Lopez-Berestein G. Regulation of a highly specific retinoic acid-4-hydroxylase (CYP26A1) enzyme and all-trans-retinoic acid metabolism in human intestinal, liver, endothelial, and acute promyelocytic leukemia cells. Leuk Lymphoma 2005; 46:1497-1506.
    • (2005) Leuk Lymphoma , vol.46 , pp. 1497-1506
    • Ozpolat, B.1    Mehta, K.2    Lopez-Berestein, G.3
  • 43
    • 0030750270 scopus 로고    scopus 로고
    • Expression of CYP3A in the human liver: Evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth
    • Lacroix D, Sonnier M, Moncion A, Cheron G, Cresteil T. Expression of CYP3A in the human liver: evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth. Eur J Biochem 1997; 247:625-634.
    • (1997) Eur J Biochem , vol.247 , pp. 625-634
    • Lacroix, D.1    Sonnier, M.2    Moncion, A.3    Cheron, G.4    Cresteil, T.5
  • 44
    • 0034664168 scopus 로고    scopus 로고
    • Identification of human cytochrome P450 isoforms that contribute to all-trans-retinoic acid 4-hydroxylation
    • McSorley LC, Daly AK. Identification of human cytochrome P450 isoforms that contribute to all-trans-retinoic acid 4-hydroxylation. Biochem Pharmacol 2000; 60:517-526.
    • (2000) Biochem Pharmacol , vol.60 , pp. 517-526
    • McSorley, L.C.1    Daly, A.K.2
  • 46
    • 17844366276 scopus 로고    scopus 로고
    • Expression of the retinoic acid-metabolizing enzyme CYP26A1 limits programmed cell death
    • Osanai M, Petkovich M. Expression of the retinoic acid-metabolizing enzyme CYP26A1 limits programmed cell death. Mol Pharmacol 2005; 67:1808-1817.
    • (2005) Mol Pharmacol , vol.67 , pp. 1808-1817
    • Osanai, M.1    Petkovich, M.2
  • 47
    • 0032033489 scopus 로고    scopus 로고
    • P450RAI (CYP26A1) maps to human chromosome 10q23-q24 and mouse chromosome 19C2-3
    • White JA, Beckett B, Scherer SW, Herbrick JA, Petkovich M. P450RAI (CYP26A1) maps to human chromosome 10q23-q24 and mouse chromosome 19C2-3. Genomics 1998; 48:270-272.
    • (1998) Genomics , vol.48 , pp. 270-272
    • White, J.A.1    Beckett, B.2    Scherer, S.W.3    Herbrick, J.A.4    Petkovich, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.