Retinoic acid and retinoid receptors: Potential chemopreventive and therapeutic role in cervical cancer

Lancet Oncology

Volumn 6, Issue 9, 2005, Pages 712-720

  Abu, Jafaru ^a   Batuwangala, Madu ^a   Herbert, Karl ^b   Symonds, Paul ^a  

^a UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALITRETINOIN; ALPHA INTERFERON; ANTIESTROGEN; ANTINEOPLASTIC AGENT; BUTYROID; CELL NUCLEUS RECEPTOR; CISPLATIN; FENRETINIDE; FISH OIL; INTERFERON; NONSTEROID ANTIINFLAMMATORY AGENT; POLYPHENOL; RETINAMIDE; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID; RETINOID X RECEPTOR; RETINOL ACETATE; RETINOL DERIVATIVE; UNCLASSIFIED DRUG; VANNILLOID;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; BONE DEVELOPMENT; CANCER CELL; CANCER CHEMOTHERAPY; CANCER INVASION; CARCINOGENESIS; CARROT; CELL DIFFERENTIATION; CELL FUNCTION; CHEMOTHERAPY INDUCED EMESIS; CLINICAL TRIAL; DESQUAMATION; DRUG POTENTIATION; DRUG RECEPTOR BINDING; EGG; EMBRYO DEVELOPMENT; FEMALE; GROWTH REGULATION; HEMATOPOIESIS; HUMAN; LIVER; MANGO; MEAT; METABOLIC REGULATION; MILK; MITOSIS INHIBITION; NEPHROTOXICITY; PRECANCER; PRIORITY JOURNAL; REGULATORY MECHANISM; REPRODUCTION; RETINOL DEFICIENCY; REVIEW; SIGNAL TRANSDUCTION; SPERMATOGENESIS; SPINACH; SURVIVAL; SWEET POTATO; TISSUE DIFFERENTIATION; UTERINE CERVIX CANCER; VAGINA DISEASE; VAGINAL PRURITUS; VIRUS PATHOGENESIS; VISION; VULVA DISEASE;

ANTINEOPLASTIC AGENTS; CERVICAL INTRAEPITHELIAL NEOPLASIA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PAPILLOMAVIRUS INFECTIONS; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; TRETINOIN; UTERINE CERVICAL NEOPLASMS;

EID: 24044526526     PISSN: 14702045     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1470-2045(05)70319-3     Document Type: Review

References (75)

1. RT Greenlee T Murray S Bolden et al. Cancer statistics, 2000 CA Cancer J Clin 50 2000 7-33
2. H Comber A Gavin Recent trends in cervical cancer mortality in Britain and Ireland: The case for population-based cervical cancer screening Br J Cancer 91 2004 1902-1904
3. BH Yang FI Bray DM Parkin et al. Cervical cancer as a priority for prevention in different world regions: An evaluation using years of life lost Int J Cancer 109 2004 418-424
4. DM Parkin Global cancer statistics in the year 2000 Lancet Oncol 2 2001 533-543
5. K Munger The role of human papillomaviruses in human cancers Front Biosci 7 2002 641-649
6. N Potischman CA Swanson RJ Coates et al. Intake of food groups and associated micronutrients in relation to risk of early-stage breast cancer Int J Cancer 82 1999 315-321
7. FL Meyskens Jr. E Surwit TE Moon et al. Enhancement of regression of cervical intraepithelial neoplasia II (moderate dysplasia) with topically applied all-trans-retinoic acid: A randomized trial J Natl Cancer Inst 86 1994 539-543
8. M Yokoyama Y Nakao T Iwasaka et al. Retinoic acid and interferon-alpha effects on cell growth and differentiation in cervical carcinoma cell lines Obstet Gynecol 98 2001 332-340
9. SM Lippman JJ Kavanagh M Paredes-Espinoza et al. 13-cis-retinoic acid plus interferon alpha-2a: Highly active systemic therapy for squamous cell carcinoma of the cervix J Natl Cancer Inst 84 1992 241-245
10. SM Lippman JJ Kavanagh M Paredes-Espinoza et al. 13-cis-retinoic acid plus interferon-alpha 2a in locally advanced squamous cell carcinoma of the cervix J Natl Cancer Inst 85 1993 499-500
11. MB Sporn AB Roberts Role of retinoids in differentiation and carcinogenesis J Natl Cancer Inst 73 1984 1381-1387
12. W Bollag EE Holdener Retinoids in cancer prevention and therapy Ann Oncol 3 1992 513-526
13. N Potischman JL Freudenheim Biomarkers of nutritional exposure and nutritional status: An overview J Nutr 133 (suppl 3) 2003 873-874
14. L Altucci H Gronemeyer The promise of retinoids to fight against cancer Nat Rev Cancer 1 2001 181-193
15. P Chambon The molecular and genetic dissection of the retinoid signaling pathway Recent Prog Horm Res 50 1995 317-332
16. DS Goodman Vitamin A and retinoids in health and disease N Engl J Med 310 1984 1023-1031
17. KR Yamamoto Steroid receptor regulated transcription of specific genes and gene networks Annu Rev Genet 19 1985 209-252
18. MR Haussler CA Donaldson MA Kelly et al. Identification and quantitation of intracellular retinol and retinoic acid binding proteins in cultured cells Biochim Biophys Acta 803 1984 54-62
19. TS Baker WW Newcomb NH Olson et al. Structures of bovine and human papillomaviruses: Analysis by cryoelectron microscopy and three-dimensional image reconstruction Biophys J 60 1991 1445-1456
20. G Sanclemente DK Gill Human papillomavirus molecular biology and pathogenesis J Eur Acad Dermatol Venereol 16 2002 231-240
21. AT Lorincz R Reid AB Jenson et al. Human papillomavirus infection of the cervix: Relative risk associations of 15 common anogenital types Obstet Gynecol 79 1992 328-337
22. H zur Hausen Cervical carcinoma and human papillomavirus: On the road to preventing a major human cancer J Natl Cancer Inst 93 2001 252-253
23. H zur Hausen Papillomavirus infections - a major cause of human cancers Biochim Biophys Acta 1288 1996 55-78
24. FX Bosch N Munoz S de Sanjose et al. Cervical carcinoma and human papillomavirus: On the road to preventing a major human cancer J Natl Cancer Inst 93 2001 1349-1350
25. RW Tindle Immune evasion in human papillomavirus-associated cervical cancer Nat Rev Cancer 2 2002 59-64
26. DJ McCance R Kopan E Fuchs et al. Human papillomavirus type 16 alters human epithelial cell differentiation in vitro Proc Natl Acad Sci USA 85 1988 7169-7173
27. K Munger WC Phelps V Bubb et al. The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes J Virol 63 1989 4417-4421
28. EC Goodwin D DiMaio Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways Proc Natl Acad Sci USA 97 2000 12513-12518
29. CK Choo EA Rorke RL Eckert Retinoid regulation of cell differentiation in a series of human papillomavirus type 16-immortalized human cervical epithelial cell lines Carcinogenesis 16 1995 375-381
30. RC Ribeiro PJ Kushner JD Baxter The nuclear hormone receptor gene superfamily Annu Rev Med 46 1995 443-453
31. JP Renaud D Moras Structural studies on nuclear receptors Cell Mol Life Sci 57 2000 1748-1769
32. S Nagpal M Saunders P Kastner et al. Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors Cell 70 1992 1007-1019
33. AC Steinmetz JP Renaud D Moras Binding of ligands and activation of transcription by nuclear receptors Annu Rev Biophys Biomol Struct 30 2001 329-359
34. P Chambon A decade of molecular biology of retinoic acid receptors FASEB J 10 1996 940-954
35. T Ivanova A Petrenko T Gritsko et al. Methylation and silencing of the retinoic acid receptor-beta 2 gene in cervical cancer BMC Cancer 2 2002 4
36. G Narayan H Arias-Pulido S Koul et al. Frequent promoter methylation of CDH1, DAPK, RARB, and HIC1 genes in carcinoma of cervix uteri: Its relationship to clinical outcome Mol Cancer 2 2003 24
37. LN Wei Retinoid receptors and their coregulators Annu Rev Pharmacol Toxicol 43 2003 47-72
38. C Leo JD Chen The SRC family of nuclear receptor coactivators Gene 245 2000 1-11
39. AJ Horlein AM Naar T Heinzel et al. Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor Nature 377 1995 397-404
40. EY Huang J Zhang EA Miska et al. Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway Genes Dev 14 2000 45-54
41. LN Wei X Hu D Chandra et al. Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing J Biol Chem 275 2000 40782-40787
42. B Durand M Saunders P Leroy et al. All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs Cell 71 1992 73-85
43. M Husmann B Hoffmann DG Stump et al. A retinoic acid response element from the rat CRBPI promoter is activated by an RAR/RXR heterodimer Biochem Biophys Res Commun 187 1992 1558-1564
44. ME Gottesman L Quadro WS Blaner Studies of vitamin A metabolism in mouse model systems Bioessays 23 2001 409-419
45. D Bellovino M Apreda S Gragnoli et al. Vitamin A transport: In vitro models for the study of RBP secretion Mol Aspects Med 24 2003 411-420
46. DJ Mangelsdorf AK Umesono RM Evans The retinoid receptors In: MB Sporn AB Roberts DS Goodman eds. The retinoids: Biochemistry, and medicine 1994 Roven Press Ltd New York 319-345
47. RM Niles Recent advances in the use of vitamin A (retinoids) in the prevention and treatment of cancer Nutrition 16 2000 1084-1089
48. C Zou M Liebert HB Grossman et al. Identification of effective retinoids for inhibiting growth and inducing apoptosis in bladder cancer cells J Urol 165 2001 986-992
49. R Lotan Retinoids and apoptosis: Implications for cancer chemoprevention and therapy J Natl Cancer Inst 87 1995 1655-1657
50. LY Fong VT Nguyen AE Pegg et al. Alpha-difluoromethylornithine induction of apoptosis: A mechanism which reverses pre-established cell proliferation and cancer initiation in esophageal carcinogenesis in zinc-deficient rats Cancer Epidemiol Biomarkers Prev 10 2001 191-199
51. YP Lu YR Lou JG Xie et al. Inhibitory effect of black tea on the growth of established skin tumors in mice: Effects on tumor size, apoptosis, mitosis and bromodeoxyuridine incorporation into DNA Carcinogenesis 18 1997 2163-2169
52. SY Sun N Hail Jr. R Lotan Apoptosis as a novel target for cancer chemoprevention J Natl Cancer Inst 96 2004 662-672
53. T Matsuo CJ Thiele p27Kip1: A key mediator of retinoic acid induced growth arrest in the SMS-KCNR human neuroblastoma cell line Oncogene 16 1998 3337-3343
54. J Langenfeld H Kiyokawa D Sekula et al. Posttranslational regulation of cyclin D1 by retinoic acid: A chemoprevention mechanism Proc Natl Acad Sci USA 94 1997 12070-12074
55. C Teixeira MA Pratt CDK2 is a target for retinoic acid-mediated growth inhibition in MCF-7 human breast cancer cells Mol Endocrinol 11 1997 1191-1202
56. IB Roninson M Dokmanovic Induction of senescence-associated growth inhibitors in the tumor-suppressive function of retinoids J Cell Biochem 88 2003 83-94
57. LJ Wainwright A Lasorella A Iavarone Distinct mechanisms of cell cycle arrest control the decision between differentiation and senescence in human neuroblastoma cells Proc Natl Acad Sci USA 98 2001 9396-9400
58. A Yen MS Roberson S Varvayanis et al. Retinoic acid induced mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase-dependent MAP kinase activation needed to elicit HL-60 cell differentiation and growth arrest Cancer Res 58 1998 3163-3172
59. JF Sah RL Eckert RA Chandraratna et al. Retinoids suppress epidermal growth factor-associated cell proliferation by inhibiting epidermal growth factor receptor-dependent ERK1/2 activation J Biol Chem 277 2002 9728-9735
60. US Singh J Pan YL Kao et al. Tissue transglutaminase mediates activation of RhoA and MAP kinase pathways during retinoic acid-induced neuronal differentiation of SH-SY5Y cells J Biol Chem 278 2003 391-399
61. MB Sporn NM Dunlop DL Newton et al. Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids) Fed Proc 35 1976 1332-1338
62. EA Surwit V Graham W Droegemueller et al. Evaluation of topically applied trans-retinoic acid in the treatment of cervical intraepithelial lesions Am J Obstet Gynecol 143 1982 821-823
63. FL Meyskens Jr. V Graham M Chvapil et al. A phase I trial of beta-all-trans-retinoic acid delivered via a collagen sponge and a cervical cap for mild or moderate intraepithelial cervical neoplasia J Natl Cancer Inst 71 1983 921-925
64. SL Romney A Dwyer S Slagle et al. Chemoprevention of cervix cancer: phase I-II: A feasibility study involving the topical vaginal administration of retinyl acetate gel Gynecol Oncol 20 1985 109-119
65. SA Weiner EA Surwit VE Graham et al. A phase I trial of topically applied trans-retinoic acid in cervical dysplasia-clinical efficacy Invest New Drugs 4 1986 241-244
66. C Ruidi D Aihua B Peiyu et al. Chemoprevention of cancer of uterine cervix: A study on chemoprevention of retinamide II from cervical precancerous lesions J Cell Biochem 28-29 Suppl 1997 140-143
67. RD Alvarez MG Conner H Weiss et al. The efficacy of 9-cis-retinoic acid (aliretinoin) as a chemopreventive agent for cervical dysplasia: Results of a randomized double-blind clinical trial Cancer Epidemiol Biomarkers Prev 12 2003 114-119
68. S Toma N Ragni P Raffo et al. Efficacy of the association of 13-cis-retinoic acid (13cRA) and alpha-interferon 2a (alpha-IFN 2a) in moderate-severe cervical intraepithelial neoplasia (CIN II-III): A pilot study Anticancer Res 16 1996 931-936
69. M Follen EN Atkinson D Schottenfeld et al. A randomized clinical trial of 4-hydroxyphenylretinamide for high-grade squamous intraepithelial lesions of the cervix Clin Cancer Res 7 2001 3356-3365
70. MT Ruffin JM Bailey DP Normolle et al. Low-dose topical delivery of all-trans retinoic acid for cervical intraepithelial neoplasia II and III Cancer Epidemiol Biomarkers Prev 13 2004 2148-2152
71. PG Rose BN Bundy EB Watkins et al. Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer N Engl J Med 340 1999 1144-1153
72. DR Scribner Jr. DM Benbrook Retinoids enhance cisplatin-based chemoradiation in cervical cancer cells in vitro Gynecol Oncol 85 2002 223-225
73. J Dunst G Hansgen C Lautenschlager et al. Oxygenation of cervical cancers during radiotherapy and radiotherapy + cis-retinoic acid/ interferon Int J Radiat Oncol Biol Phys 43 1999 367-373
74. G Haensgen U Krause A Becker et al. Tumor hypoxia, p53, and prognosis in cervical cancers Int J Radiat Oncol Biol Phys 50 2001 865-872
75. M Durst D Glitz A Schneider et al. Human papillomavirus type 16 (HPV 16) gene expression and DNA replication in cervical neoplasia: Analysis by in situ hybridization Virology 189 1992 132-140