Cyclooxygenase-2 inhibitor reduces simvastatin-induced bone morphogenetic protein-2 and bone formation in vivo

Journal of Periodontal Research

Volumn 42, Issue 3, 2007, Pages 267-273

  Bradley, J D ^a   Cleverly, D G ^a   Burns, A M ^a   Helm, N B ^a   Schmid, M J ^a   Marx, D B ^b   Cullen, D M ^c   Reinhardt, R A ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^c CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bone formation rate; Bone morphogenetic protein 2; Cyclooxygenase 2; Simvastatin

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; ENZYME INHIBITOR; HYPOCHOLESTEROLEMIC AGENT; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; N(G) NITROARGININE METHYL ESTER; N-(2-CYCLOHEXYLOXY-4-NITROPHENYL)METHANESULFONAMIDE; NITRIC OXIDE SYNTHASE; NITROBENZENE DERIVATIVE; SIMVASTATIN; SULFONAMIDE; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; BONE DEVELOPMENT; DRUG EFFECT; METABOLISM; RAT;

ANIMALS; ANTICHOLESTEREMIC AGENTS; BONE MORPHOGENETIC PROTEINS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; ENZYME INHIBITORS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITROBENZENES; OSTEOGENESIS; RATS; SIMVASTATIN; SULFONAMIDES;

EID: 34247509367     PISSN: 00223484     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2006.00943.x     Document Type: Article

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