Nitric oxide synthase and cyclo-oxygenase pathways in the inflammatory response induced by zymosan in the rat air pouch

British Journal of Pharmacology

Volumn 120, Issue 8, 1997, Pages 1445-1452

  Payá, Miguel ^a   Pastor, Pablo García ^a   Coloma, Julio ^a   Alcaraz, M José ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Aminoguanidine; Cyclo oxygenase 2; Dexamethasone; Inducible nitric oxide synthase; N(G) nitro L arginine methyl ester; NS398; Rat air pouch; Zymosan

Indexed keywords

AMINOGUANIDINE; COLCHICINE; CYCLOOXYGENASE 2 INHIBITOR; DEXAMETHASONE; ELASTASE; LEUKOTRIENE B4; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; N(G) NITROARGININE METHYL ESTER; NITRATE; NITRIC OXIDE SYNTHASE; NITRITE; PHOSPHOLIPASE A2; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; ZYMOSAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CHEMOLUMINESCENCE; CONTROLLED STUDY; ENZYME INDUCTION; ENZYME RELEASE; FEMALE; IMMUNOBLOTTING; INFLAMMATION; LEUKOCYTE; LYMPHOCYTE; MONOCYTE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030936095     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701073     Document Type: Article

References (56)

1. ANDERSON, G.D., HAUSER, S.D., MCGARITY, K.L., BREMER, M.E., ISAKSON, P.C. & GREGORY, S.A. (1996). Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis. J. Clin. Invest., 97, 2672-2679.
2. BRADFORD, M.M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
3. BRYANT, J.L., JR., MEHTA, P., VON DER PORTEN, A. & MEHTA, J.L. (1992). Co-purification of 130 KD nitric oxide synthase and a 22 KD link protein from human neutrophils. Biochem. Biophys. Res. Commun., 189, 558-564.
4. BUSTOS, G., FERRÀNDIZ, M.L., SANZ, M.J., PAYÁ, M. & ALCARAZ, M.J. (1995). A study of the novel anti-inflammatory agent florifenine. Topical anti-inflammatory activity and influence on arachidonic acid metabolism and neutrophil functions. Naunyn-Schmiedeberg's Arch. Pharmacol., 351, 298-304.
5. CLANCY, R.M., LESZCZYNSKA-PIZIAK, J. & ABRAMSON, S.B. (1992). Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase. J. Clin. Invest., 90, 1116-1121.
6. CONNOR, J.R., MANNING, P.T., SETTLE, S.L., MOORE, W.M., JEROME, G.M., WEBBER, R.K., TJOENG, F.S. & CURRIE, M.G. (1995). Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase. Eur. J. Pharmacol., 273, 15-24.
7. DIKSHIT, M., CHARI, S.S., SETH, P. & KUMARI, R. (1996). Interaction of nitric oxide synthase inhibitors and their D-enantiomers with rat neutrophil luminol dependent chemiluminescence response. Br. J. Pharmacol., 119, 578-582.
8. DRAPIER, J.C., WIETZERBIN, J. & HIBBS, J.B.J. (1988). Interferon-gamma and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages. Eur. J. Immunol., 18, 1587-1592.
9. EDWARDS, J.C.W., SEDGWICK, A.D. & WILLOUGHBY, D.A. (1981). The formation of a structure with the features of synovial lining by subcutaneous injection of air: an in vivo tissue culture system. J. Pathol., 134, 147-156.
10. FARRELL, A.J., BLAKE, D.R., PALMER, R.M.J. & MONCADA, S. (1992). Increased concentrations of nitric in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases. Ann. Rheum. Dis., 51, 1219-1222.
11. FERRÁNDIZ, M.L. & FOSTER, S.J. (1991). Tumour necrosis factor production in a rat airpouch model of inflammation: role of eicosanoids. Agents Actions, 32, 289-294.
12. 2 associated with rabbit polymorphonuclear leukocyte granules. J. Lipid Res., 15, 380-388.
13. 2 synthase (cyclooxygenase) in human monocytes. J. Biol. Chem., 265, 16737-16740.
14. GRABOWSKI, P.S., ENGLAND, A.J., DYKHUIZEN, R., COPLAND, M., BENJAMIN, N., REID, D.M. & RALSTON, S.H. (1996). Elevated nitric oxide production in rheumatoid arthritis. Arthritis Rheum., 39, 643-647.
15. HONORÉ, P., CHAPMAN, V., BURITOVA, J. & BESSON, J.-M. (1995). Reduction of carrageenin oedema and the associated c-Fos expression in the rat lumbar spinal cord by nitric oxide synthase inhibitor. Br. J. Pharmacol., 114, 77-84.
16. IALENTI, A., MONCADA, S. & DI ROSA, M. (1993). Modulation of adjuvant arthritis by endogenous nitric oxide. Br. J. Pharmacol., 110, 701-705.
17. IUVONE, T., CARNUCCIO, R. & DI ROSA, M. (1994). Modulation of granuloma formation by endogenous nitric oxide. Eur. J. Pharmacol., 265, 89-92.
18. JOSE, P.J. (1987). Complement-derived peptide mediators of inflammation. Br. Med. Bull., 43, 336-349.
19. KAUR, H. & HALLIWELL, B. (1994). Evidence for nitric oxide-mediated oxidative damage in chronic inflammation. Nitrotyrosine in serum and synovial fluid from rheumatoid patients. FEBS Lett., 350, 9-12.
20. KLEBANOFF, S.J. (1993). Reactive nitrogen intermediates and antimicrobial activity: role of nitrite. Free Rad. Biol. Med., 14, 351-360.
21. KNOWLES, R.G., MERRETT, M., SALTER, M. & MONCADA, S. (1990). Differential induction of brain, lung and liver nitric oxide synthase by endotoxin in the rat. Biochem. J., 270, 833-836.
22. KNOWLES, R.G. & MONCADA, S. (1994). Nitric oxide synthases in mammals. Biochem. J., 298, 249-258.
23. KOLLS, J, XIE, J., LEBLANC, R., MALINSKI, T., NELSON, S., SUMMER, W. & GREENBERG, S.S. (1994). Rapid induction of messenger RNA for nitric oxide synthase II in rat neutrophils in vivo by endotoxin and its suppression by prednisolone. Proc. Soc. Exp. Biol. Med., 205, 220-225.
24. KONNO, S. & TSURUFUJI, S. (1983). Induction of zymosan-air-pouch inflammation in rats and its characterization with reference to the effects of anticomplementary and anti-inflammatory agents. Br. J. Pharmacol., 80, 269-277.
25. KUROSE, I., KUBES, P., WOLF, R., ANDERSON, D.C., PAULSON, J., MIYASAKA, M. & GRANGER, D.N. (1993). Inhibition of nitric oxide production. Mechanisms of vascular albumin leakage. Circ. Res., 73, 164-171.
26. LIPPE, I.T., STABENTHEINER, A. & HOLZER, P. (1993). Participation of nitric oxide in the mustard oil-induced neurogenic inflammation of the rat paw skin. Eur. J. Pharmacol., 232, 113-120.
27. MAROTTA, P., SAUTEBIN, L. & DI ROSA, M. (1992). Modulation of the induction of nitric oxide synthase by eicosanoids in the murine macrophage cell line J774.2 cells. Br. J. Pharmacol., 107, 640-641.
28. MASFERRER, J.L., ZWEIFEL, B.S. & NEEDLEMAN, P. (1990). Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice. J. Clin. Invent., 86, 1375-1379.
29. MASFERRER, J.L., ZWEIFEL, B.S., MANNING, P.T., HAUSER, S.D., LEAHY, K.M., SMITH, W.G., ISAKSON, P.C. & SEIBERT, K. (1994). Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic. Proc. Natl. Acad. Sci. U.S.A., 91, 3228-3232.
30. MCCALL, T.B., BOUGHTON-SMITH, N.K., PALMER, R.M.J., WHITTLE, B.J.R. & MONCADA, S. (1989). Synthesis of nitric oxide from L-arginine by neutrophils. Release and interaction with superoxide anion. Biochem. J., 261, 293-296.
31. MCCARTNEY FRANCIS, N., ALLEN, J.B., MIZEL, D.E., ALBINA, J.E., XIE, Q.W., NATHAN, C.F. & WAHL, S.M. (1993). Suppression of arthritis by an inhibitor of nitric oxide synthase. J. Exp. Med., 178, 749-754.
32. MEDEIROS, M.V., BINHARA, I.M., MORENO, H., ZATZ, R., DE NUCCI, G. & ANTUNES, E. (1995). Effect of chronic nitric oxide synthesis inhibition on the inflammatory responses induced by carrageenin in rats. Eur. J. Pharmacol., 285, 109-114.
33. MISKO, T.P., SCHILLING, R.J., SALVEMINI, D., MOORE, W.M. & CURRIE, M.G. (1993). A fluorometric assay for the measurement of nitrite in biological samples. Anal. Biochem., 214, 11-16.
34. MITCHELL, J.A., SHENG, H. FÖRSTERMANN, U. & MURAD, F. (1991). Characterization of nitric oxide synthases in non-adrenergic non-cholinergic nerve containing tissue from the rat anococcygeus muscle. Br. J. Pharmacol., 104, 289-291.
35. MORONEY, M.A., ALCARAZ, M.J., FORDER, R.A., CAREY, F. & HOULT, J.R.S. (1988). Selectivity of neutrophil 5-lipoxygenase and cyclo-oxygenase inhibition by an anti-inflammatory flavonoid glycoside and related aglycone flavonoids. J. Pharm. Pharmacol., 40, 787-792.
36. PALMER, R.M.J., FERRIGE, A.G. & MONCADA, S. (1987). Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature, 327, 524-526.
37. 2 activity in the zymosan rat air pouch model of inflammation. Br. J. Pharmacol., 117, 1773-1779.
38. PERRETTI, M., SOLITO, E. & PARENTE, L. (1992). Evidence that endogenous interleukin-1 is involved in leukocyte migration in acute experimental inflammation in rats and mice. Agents Actions, 35, 71-78.
39. PERRETTI, M., SZABÓ, C. & THIEMERMANN, C. (1995). Effect of interleukin-4 and interleukin-10 on leucocyte migration and nitric oxide production in the mouse. Br. J. Pharmacol., 116, 2251-2257.
40. RADOMSKI, M.W., PALMER, R.M.J. & MONCADA, S. (1990). Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells. Proc. Natl. Acad. Sci. U.S.A., 87, 10043-10047.
41. SALVEMINI, D., MANNING, P.T., ZWEIFEL, B.S., SEIBERT, K., CONNOR, J., CURRIE, M.G., NEEDLEMAN, P. & MASFERRER, J.L. (1995a). Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors. J. Clin. Invest., 96, 301-308.
42. SALVEMINI, D., MISKO, T.P., MASFERRER, J.L., SEIBERT, K., CURRIE, M.G. & NEEDLEMAN, P. (1993). Nitric oxide activates cyclooxygenase enzymes. Proc. Natl. Acad. Sci. U.S.A., 90, 7240-7244.
43. SALVEMINI, D., SETTLE, S.L., MASFERRER, J.L., SEIBERT, K., CURRIE, M.G. & NEEDLEMAN, P. (1995b). Regulation of prostaglandin production by nitric oxide: an in vivo analysis. Br. J. Pharmacol., 114, 1171-1178.
44. SALVEMINI, D., WANG, Z.-Q., WYATT, P.S., BOURDON, D.M., MARINO, M.H., MANNING, P.T. & CURRIE, M.G. (1996). Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. Br. J. Pharmacol., 118, 829-838.
45. SAUTEBIN, L., IALENTI, A., IANARO, A. & DI ROSA, M. (1995). Modulation by nitric oxide of prostaglandin biosynthesis in the rat. Br. J. Pharmacol., 114, 323-328.
46. SCHORLEMMER, H.U., EDWARDS, J.H., DAVIES, P. & ALLISON, A.C. (1977). Macrophage responses to mouldy hay dust, Micropolyspora faeni and zymosan, activators of complement by the alternative pathway. Clin. Exp. Immunol., 27, 198-203.
47. SMITH, J.A. (1994). Neutrophils, host defense, and inflammation: a double-edged sword. J. Leukoc. Biol., 56, 672-686.
48. STEFANOVIC-RACIC, M., MEYERS, K., MESCHTER, C., COFFEY, J.W., HOFFMAN, R.A. & EVANS, C.H. (1994). N-Monomethyl arginine, an inhibitor of nitric oxide synthase, suppresses the development of adjuvant arthritis in rats. Arthritis Rheum., 37, 1062-1069.
49. SWIERKOSZ, T.A., MITCHELL, J.A., WARNER, T.D., BOTTING, R.M. & VANE, J.R. (1995). Co-induction of nitric oxide synthase and cyclo-oxygenase: interactions between nitric oxide and prostanoids. Br. J. Pharmacol., 114, 1335-1342.
50. 2 negatively modulates induction of nitric oxide synthase by interleukin 1. Proc. Natl. Acad. Sci. U.S.A., 91, 12168-12172.
51. TOMLINSON, A., APPLETON, I., MOORE, A.R., GILROY, D.W., WILLIS, D., MITCHELL, J.A. & WILLOUGHBY, D.A. (1994). Cyclo-oxygenase and nitric oxide synthase isoforms in rat carrageenan-induced pleurisy. Br. J. Pharmacol., 113, 693-698.
52. G-monomethylarginine, reduces carrageenan-induced pleurisy in the rat. J. Pharmacol. Exp. Ther., 273, 1295-1299.
53. VANE, J.R., MITCHELL, J.A., APPLETON, I., TOMLINSON, A., BISHOP-BAILEY, D., CROXTALL, J. & WILLOUGHBY, D.A. (1994). Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. Proc. Natl. Acad. Sci. U.S.A., 91, 2046-2050.
54. WEDMORE, C.V. & WILLIAMS, T.J. (1981). Control of vascular permeability by polymorphonuclear leukocytes in inflammation. Nature, 289, 646-650.
55. WRIGHT, C.D., MÜLSCH, A., BUSSE, R. & OSSWALD, H. (1989). Generation of nitric oxide by human neutrophils. Biochem. Biophys. Res. Commun., 160, 813-819.
56. WU, C.-C., CROXTALL, J.D., PERRETTI, M., BRYANT, C.E., THIEMERMANN, C., FLOWER, R.J. & VANE, J.R. (1995). Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat. Proc. Natl. Acad. Sci. U.S.A., 92, 3473-3477.