-
1
-
-
77956929978
-
Cyclic nucleotide-dependent protein kinases
-
Boyer PD, Kerbes EG, editors, New York: Academic;
-
Beebe SJ, Corbin JD. Cyclic nucleotide-dependent protein kinases. In: Boyer PD, Kerbes EG, editors. The enzymes: control by phosphorylation. New York: Academic; 1986. Vol. 17. p. 43-111.
-
(1986)
The enzymes: Control by phosphorylation
, vol.17
, pp. 43-111
-
-
Beebe, S.J.1
Corbin, J.D.2
-
2
-
-
0029565543
-
cAMP-dependent protein kinase: Role in normal and malignant growth
-
Cho-Chung YS, Pepe S, Clair T, Budillon A, Nesterova M. cAMP-dependent protein kinase: role in normal and malignant growth. Crit Rev Oncol Hematol 1995;21:33-61.
-
(1995)
Crit Rev Oncol Hematol
, vol.21
, pp. 33-61
-
-
Cho-Chung, Y.S.1
Pepe, S.2
Clair, T.3
Budillon, A.4
Nesterova, M.5
-
3
-
-
9444247656
-
Minireview: PRKAR1A: normal and abnormal functions
-
Bossis I, Stratakis CA. Minireview: PRKAR1A: normal and abnormal functions. Endocrinology 2004;145:5452-8.
-
(2004)
Endocrinology
, vol.145
, pp. 5452-5458
-
-
Bossis, I.1
Stratakis, C.A.2
-
4
-
-
0038335335
-
cAMP signaling in cancer genesis and treatment
-
Cho-Chung YS. cAMP signaling in cancer genesis and treatment. Cancer Treat Res 2003;115:123-43.
-
(2003)
Cancer Treat Res
, vol.115
, pp. 123-143
-
-
Cho-Chung, Y.S.1
-
6
-
-
3042547294
-
Protein kinase A and its role in human neoplasia: The Carney complex paradigm
-
Bossis I, Voutetakis A, Bei T, Sandrini F, Griffin KJ, Stratakis CA. Protein kinase A and its role in human neoplasia: the Carney complex paradigm. Endocr Relat Cancer 2004;11:265-80.
-
(2004)
Endocr Relat Cancer
, vol.11
, pp. 265-280
-
-
Bossis, I.1
Voutetakis, A.2
Bei, T.3
Sandrini, F.4
Griffin, K.J.5
Stratakis, C.A.6
-
7
-
-
0004989201
-
Extracellular protein kinase A as a cancer biomarker: Its expression by tumor cells and reversal by a myristate-lacking Cα and RIIβ subunit overexpression
-
Cho YS, Park YG, Lee YN, et al. Extracellular protein kinase A as a cancer biomarker: its expression by tumor cells and reversal by a myristate-lacking Cα and RIIβ subunit overexpression. Proc Natl Acad Sci U S A 2000;97:835-40.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 835-840
-
-
Cho, Y.S.1
Park, Y.G.2
Lee, Y.N.3
-
8
-
-
0001313798
-
Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase
-
Uhler MD, Carmichael DF, Lee DC, Chivia JC, Krebs EG, McKnight GS. Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase. Proc Natl Acad Sci U S A 1986;83:1300-4.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 1300-1304
-
-
Uhler, M.D.1
Carmichael, D.F.2
Lee, D.C.3
Chivia, J.C.4
Krebs, E.G.5
McKnight, G.S.6
-
9
-
-
0023000363
-
Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase
-
Uhler MD, Chrivia JC, McKnight GS. Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase. J Biol Chem 1986;261: 15360-3.
-
(1986)
J Biol Chem
, vol.261
, pp. 15360-15363
-
-
Uhler, M.D.1
Chrivia, J.C.2
McKnight, G.S.3
-
10
-
-
0025343605
-
Molecular cloning of a tissue-specific protein kinase (Cγ) from human testis - representing a third isoform for the catalytic subunit of cAMP-dependent protein kinase
-
Beebe SJ, Oyen O, Sandberg M, Froysa A, Hansson V, Jahnsen T. Molecular cloning of a tissue-specific protein kinase (Cγ) from human testis - representing a third isoform for the catalytic subunit of cAMP-dependent protein kinase. Mol Endocrinol 1990;4:465-75.
-
(1990)
Mol Endocrinol
, vol.4
, pp. 465-475
-
-
Beebe, S.J.1
Oyen, O.2
Sandberg, M.3
Froysa, A.4
Hansson, V.5
Jahnsen, T.6
-
11
-
-
0024232624
-
-
Levy FO, Oyen O, Sandberg M, et al. Molecular cloning, complementary deoxyribonucleic acid structure and predicted full-length amino acid sequence of the hormone-inducible regulatory subunit of 3′-5′ - cyclic adenosine monophosphate-dependent protein kinase from human testis. MoI Endocrinol 1988;2:1364-73.
-
Levy FO, Oyen O, Sandberg M, et al. Molecular cloning, complementary deoxyribonucleic acid structure and predicted full-length amino acid sequence of the hormone-inducible regulatory subunit of 3′-5′ - cyclic adenosine monophosphate-dependent protein kinase from human testis. MoI Endocrinol 1988;2:1364-73.
-
-
-
-
12
-
-
0027858371
-
The regulatory subunit of cAMP-dependent protein kinase as a target for chemotherapy of cancer and other cellular dysfunctional related diseases
-
Cho-Chung YS, Clair T. The regulatory subunit of cAMP-dependent protein kinase as a target for chemotherapy of cancer and other cellular dysfunctional related diseases. Pharmacol Ther 1993;60:265-88.
-
(1993)
Pharmacol Ther
, vol.60
, pp. 265-288
-
-
Cho-Chung, Y.S.1
Clair, T.2
-
13
-
-
0032587480
-
Increased expression of the RIα subunit of the cAMP-dependent protein kinase A is associated with advanced stage ovarian cancer
-
McDaid HM, Cairns MT, Atkinson RJ, et al. Increased expression of the RIα subunit of the cAMP-dependent protein kinase A is associated with advanced stage ovarian cancer. Br J Cancer 1999;79:933-9.
-
(1999)
Br J Cancer
, vol.79
, pp. 933-939
-
-
McDaid, H.M.1
Cairns, M.T.2
Atkinson, R.J.3
-
14
-
-
0032575384
-
Effects of RIα overexpression on cisplatin sensitivity in human ovarian carcinoma cells
-
Cvijic ME, Chin KV. Effects of RIα overexpression on cisplatin sensitivity in human ovarian carcinoma cells. Biochem Biophys Res Commun 1998;249: 723-7.
-
(1998)
Biochem Biophys Res Commun
, vol.249
, pp. 723-727
-
-
Cvijic, M.E.1
Chin, K.V.2
-
15
-
-
0028218440
-
Protein kinase A (PK-A) regulatory subunit expression in colorectal cancer and related mucosa
-
Bradbury AW, Carter DC, Miller WR, Cho-Chung YS, Clair T. Protein kinase A (PK-A) regulatory subunit expression in colorectal cancer and related mucosa. Br J Cancer 1994;69:738-42.
-
(1994)
Br J Cancer
, vol.69
, pp. 738-742
-
-
Bradbury, A.W.1
Carter, D.C.2
Miller, W.R.3
Cho-Chung, Y.S.4
Clair, T.5
-
16
-
-
0031418311
-
Changes in messenger RNA expression of protein kinase A regulatory subunit Iα in breast cancer patients treated with tamoxifen
-
Miller WR, Hulme MJ, Bartlett JM, MacCallum J, Dixon JM. Changes in messenger RNA expression of protein kinase A regulatory subunit Iα in breast cancer patients treated with tamoxifen. Clin Cancer Res 1997;3:2399-404.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 2399-2404
-
-
Miller, W.R.1
Hulme, M.J.2
Bartlett, J.M.3
MacCallum, J.4
Dixon, J.M.5
-
17
-
-
0028905090
-
Regulation of Lewis lung carcinoma invasion and metastasis by protein kinase A
-
Young MR, Montpetit M, Lozano Y, et al. Regulation of Lewis lung carcinoma invasion and metastasis by protein kinase A. Int J Cancer 1995;61: 104-9.
-
(1995)
Int J Cancer
, vol.61
, pp. 104-109
-
-
Young, M.R.1
Montpetit, M.2
Lozano, Y.3
-
18
-
-
0032491195
-
Novel function of the regulatory subunit of protein kinase A: Regulation of cytochrome c oxidase activity and cytochrome c release
-
Yang WL, Iacono L, Tang WM, Chin KV. Novel function of the regulatory subunit of protein kinase A: regulation of cytochrome c oxidase activity and cytochrome c release. Biochemistry 1998;37:14175-80.
-
(1998)
Biochemistry
, vol.37
, pp. 14175-14180
-
-
Yang, W.L.1
Iacono, L.2
Tang, W.M.3
Chin, K.V.4
-
19
-
-
0025345655
-
Transfection of a mutant regulatory subunit gene of cAMP-dependent protein kinase causes increased drug sensitivity and decreased expression of P-glycoprotein
-
Abraham I, Chin KV, Gottesman MM, Mayo JK, Sampson KE. Transfection of a mutant regulatory subunit gene of cAMP-dependent protein kinase causes increased drug sensitivity and decreased expression of P-glycoprotein. Exp Cell Res 1990;189:133-41.
-
(1990)
Exp Cell Res
, vol.189
, pp. 133-141
-
-
Abraham, I.1
Chin, K.V.2
Gottesman, M.M.3
Mayo, J.K.4
Sampson, K.E.5
-
20
-
-
0029033086
-
Regulation of multidrug resistance through the cAMP and EGF signalling pathways
-
Rohlff C, Glazer R. Regulation of multidrug resistance through the cAMP and EGF signalling pathways. Cell Signal 1995;7:431-4.
-
(1995)
Cell Signal
, vol.7
, pp. 431-434
-
-
Rohlff, C.1
Glazer, R.2
-
21
-
-
31344452370
-
Radiosensitization by targeting radioresistance-related genes with protein kinase A inhibitor in radioresistant cancer cells
-
Chin C, Bae JH, Kim MJ, et al. Radiosensitization by targeting radioresistance-related genes with protein kinase A inhibitor in radioresistant cancer cells. Exp Mol Med 2005;37:608-18.
-
(2005)
Exp Mol Med
, vol.37
, pp. 608-618
-
-
Chin, C.1
Bae, J.H.2
Kim, M.J.3
-
22
-
-
0025222504
-
Role of cyclic AMP receptor proteins in growth, differentiation, and suppression of malignancy: New approaches to therapy
-
Cho-Chung YS. Role of cyclic AMP receptor proteins in growth, differentiation, and suppression of malignancy: new approaches to therapy. Cancer Res 1990;50:7093-100.
-
(1990)
Cancer Res
, vol.50
, pp. 7093-7100
-
-
Cho-Chung, Y.S.1
-
24
-
-
0034735986
-
Biochemical characterization of extracellular cAMP-dependent protein kinase as a tumor marker
-
Cho YS, Lee YN, Cho-Chung YS. Biochemical characterization of extracellular cAMP-dependent protein kinase as a tumor marker. Biochem Biophys Res Commun 2002;278:679-84.
-
(2002)
Biochem Biophys Res Commun
, vol.278
, pp. 679-684
-
-
Cho, Y.S.1
Lee, Y.N.2
Cho-Chung, Y.S.3
-
25
-
-
3342953979
-
Activation of protein kinase A (PKA) by 8-Cl-cAMP as a novel approach for antileukaemic therapy
-
Weissinger EM, Oettrich K, Evans C, et al. Activation of protein kinase A (PKA) by 8-Cl-cAMP as a novel approach for antileukaemic therapy. Br J Cancer 2004;91:186-92.
-
(2004)
Br J Cancer
, vol.91
, pp. 186-192
-
-
Weissinger, E.M.1
Oettrich, K.2
Evans, C.3
-
26
-
-
0036297650
-
Protein kinase A as target for novel integrated strategies of cancer therapy
-
Tortora G, Ciardiello F. Protein kinase A as target for novel integrated strategies of cancer therapy. Ann N Y Acad Sci 2002;968:139-47.
-
(2002)
Ann N Y Acad Sci
, vol.968
, pp. 139-147
-
-
Tortora, G.1
Ciardiello, F.2
-
27
-
-
22244455071
-
Oncogenes as novel targets for cancer therapy (part I): Growth factors and protein tyrosine kinases
-
Zhang Z, Li M, Rayburn ER, Hill DL, Zhang R, Wang H. Oncogenes as novel targets for cancer therapy (part I): growth factors and protein tyrosine kinases. Am J Pharmacogenomics 2005;5:173-90.
-
(2005)
Am J Pharmacogenomics
, vol.5
, pp. 173-190
-
-
Zhang, Z.1
Li, M.2
Rayburn, E.R.3
Hill, D.L.4
Zhang, R.5
Wang, H.6
-
28
-
-
33745312193
-
Chemoprevention with protein kinase A RIα antisense in DMBA-mammary carcinogenesis
-
Nesterova MV, Cho-Chung YS. Chemoprevention with protein kinase A RIα antisense in DMBA-mammary carcinogenesis. Ann N Y Acad Sci 2005;1058: 255-64.
-
(2005)
Ann N Y Acad Sci
, vol.1058
, pp. 255-264
-
-
Nesterova, M.V.1
Cho-Chung, Y.S.2
-
29
-
-
3042770595
-
Antisense protein kinase A RIα inhibits 7,12-dimethylbenz(a)anthracene-induction of mammary cancer: Blockade at the initial phase of carcinogenesis
-
Nesterova MV, Cho-Chung YS. Antisense protein kinase A RIα inhibits 7,12-dimethylbenz(a)anthracene-induction of mammary cancer: blockade at the initial phase of carcinogenesis. Clin Cancer Res 2004;10:4568-77.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4568-4577
-
-
Nesterova, M.V.1
Cho-Chung, Y.S.2
-
30
-
-
0033623173
-
Compensatory stabilization of RIIβ protein, cell cycle deregulation, and growth arrest in colon and prostate carcinoma cells by antisense-directed down-regulation of protein kinase A RIα protein
-
Nesterova M, Noguchi K, Park YG, Lee YN, Cho-Chung YS. Compensatory stabilization of RIIβ protein, cell cycle deregulation, and growth arrest in colon and prostate carcinoma cells by antisense-directed down-regulation of protein kinase A RIα protein. Clin Cancer Res 2000;6:3434-41.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 3434-3441
-
-
Nesterova, M.1
Noguchi, K.2
Park, Y.G.3
Lee, Y.N.4
Cho-Chung, Y.S.5
-
31
-
-
0030835506
-
Characterization of a cAMP-dependent protein kinase mutant resistant to cisplatin
-
Cvijic ME, Chin KV. Characterization of a cAMP-dependent protein kinase mutant resistant to cisplatin. Int J Cancer 1997;72:345-50.
-
(1997)
Int J Cancer
, vol.72
, pp. 345-350
-
-
Cvijic, M.E.1
Chin, K.V.2
-
32
-
-
0033598705
-
Antitumor activity and pharmacokinetics of a mixed-backbone antisense oligonucleotide targeted to the RIα subunit of protein kinase A after oral administration
-
Wang H, Cai Q, Zeng X, Yu D, Agrawal S, Zhang R. Antitumor activity and pharmacokinetics of a mixed-backbone antisense oligonucleotide targeted to the RIα subunit of protein kinase A after oral administration. Proc Natl Acad Sci U S A 1999;96:13989-94.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 13989-13994
-
-
Wang, H.1
Cai, Q.2
Zeng, X.3
Yu, D.4
Agrawal, S.5
Zhang, R.6
-
33
-
-
0036653149
-
Antisense oligonucleotide targeted to RIα subunit of cAMP-dependent protein kinase (GEM231) enhances therapeutic effectiveness of cancer chemotherapeutic agent irinotecan in nude mice bearing human cancer xenografts: In vivo synergistic activity, pharmacokinetics and host toxicity
-
Wang H, Hang J, Shi Z, et al. Antisense oligonucleotide targeted to RIα subunit of cAMP-dependent protein kinase (GEM231) enhances therapeutic effectiveness of cancer chemotherapeutic agent irinotecan in nude mice bearing human cancer xenografts: in vivo synergistic activity, pharmacokinetics and host toxicity. Int J Oncol 2002;21:73-80.
-
(2002)
Int J Oncol
, vol.21
, pp. 73-80
-
-
Wang, H.1
Hang, J.2
Shi, Z.3
-
34
-
-
1342289728
-
Clinical studies in patients with solid tumors using a second-generation antisense oligonucleotide (GEM 231) targeted against protein kinase A type I
-
Mani S, Goel S, Nesterova M, et al. Clinical studies in patients with solid tumors using a second-generation antisense oligonucleotide (GEM 231) targeted against protein kinase A type I. Ann N Y Acad Sci 2003;1002: 252-62.
-
(2003)
Ann N Y Acad Sci
, vol.1002
, pp. 252-262
-
-
Mani, S.1
Goel, S.2
Nesterova, M.3
-
35
-
-
0035859872
-
Antisense DNAs as multisite genomic modulators identified by DNA microarray
-
Cho YS, Kim MK, Cheadle C, Neary C, Becker KG, Cho-Chung YS. Antisense DNAs as multisite genomic modulators identified by DNA microarray. Proc Natl Acad Sci U S A 2001;98:9819-23.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 9819-9823
-
-
Cho, Y.S.1
Kim, M.K.2
Cheadle, C.3
Neary, C.4
Becker, K.G.5
Cho-Chung, Y.S.6
-
36
-
-
27744523250
-
Tumor markers in breast cancer - European Group on Tumor Markers recommendations
-
Molina R, Barak V, van Dalen A, et al. Tumor markers in breast cancer - European Group on Tumor Markers recommendations. Tumour Biol 2005; 26:281-93.
-
(2005)
Tumour Biol
, vol.26
, pp. 281-293
-
-
Molina, R.1
Barak, V.2
van Dalen, A.3
-
37
-
-
1642304085
-
CA 125 elevation in breast cancer: A case report and review of the literature
-
Leonard GD, Low JA, Berman AW, Swain SM. CA 125 elevation in breast cancer: a case report and review of the literature. Breast J 2004;10:146-9.
-
(2004)
Breast J
, vol.10
, pp. 146-149
-
-
Leonard, G.D.1
Low, J.A.2
Berman, A.W.3
Swain, S.M.4
-
38
-
-
3042663483
-
Detection of prostate cancer and predicting progression: Current and future diagnostic markers
-
Tricoli JV, Schoenfeldt M, Conley BA. Detection of prostate cancer and predicting progression: current and future diagnostic markers. Clin Cancer Res 2004;10:3943-53.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3943-3953
-
-
Tricoli, J.V.1
Schoenfeldt, M.2
Conley, B.A.3
-
39
-
-
20444374483
-
Circulating tumour-derived DNA and RNA markers in blood: A tool for early detection, diagnostics, and follow-up?
-
Bremnes RM, Sirera R, Camps C. Circulating tumour-derived DNA and RNA markers in blood: a tool for early detection, diagnostics, and follow-up? Lung Cancer 2005;49:1-12.
-
(2005)
Lung Cancer
, vol.49
, pp. 1-12
-
-
Bremnes, R.M.1
Sirera, R.2
Camps, C.3
-
40
-
-
4344590372
-
Recent progress in predictive biomarkers for metastatic recurrence of human hepatocellular carcinoma: A review of the literature
-
Qin LX, Tang ZY. Recent progress in predictive biomarkers for metastatic recurrence of human hepatocellular carcinoma: a review of the literature. J Cancer Res Clin Oncol 2004;130:497-513.
-
(2004)
J Cancer Res Clin Oncol
, vol.130
, pp. 497-513
-
-
Qin, L.X.1
Tang, Z.Y.2
-
41
-
-
14744274613
-
Early diagnosis of lung cancer by detection of tumor liberated protein
-
Tarro G, Perna A, Esposito C. Early diagnosis of lung cancer by detection of tumor liberated protein. J Cell Physiol 2005;203:1-5.
-
(2005)
J Cell Physiol
, vol.203
, pp. 1-5
-
-
Tarro, G.1
Perna, A.2
Esposito, C.3
-
42
-
-
0034651811
-
Proteases in gastrointestinal neoplastic diseases
-
Herszenyi L, Plebani M, Carrara P, et al. Proteases in gastrointestinal neoplastic diseases. Clin Chim Acta 2000;291:171-87.
-
(2000)
Clin Chim Acta
, vol.291
, pp. 171-187
-
-
Herszenyi, L.1
Plebani, M.2
Carrara, P.3
-
43
-
-
0030849170
-
The prognostic importance of tumor markers in adenocarcinomas of the gastrointestinal tract
-
Grem J. The prognostic importance of tumor markers in adenocarcinomas of the gastrointestinal tract. Curr Opin Oncol 1997;9:380-7.
-
(1997)
Curr Opin Oncol
, vol.9
, pp. 380-387
-
-
Grem, J.1
-
45
-
-
22244448395
-
Applying proteomics in clinical trials: Assessing the potential and practical limitations in ovarian cancer
-
Tchabo NE, Liel MS, Kohn EC. Applying proteomics in clinical trials: assessing the potential and practical limitations in ovarian cancer. Am J Pharmacogenomics 2005;5:141-8.
-
(2005)
Am J Pharmacogenomics
, vol.5
, pp. 141-148
-
-
Tchabo, N.E.1
Liel, M.S.2
Kohn, E.C.3
-
46
-
-
0142153404
-
Objective measurement of remission and progression in metastatic breast cancer by the use of serum tumour markers
-
Cheung KL, Robertson FR. Objective measurement of remission and progression in metastatic breast cancer by the use of serum tumour markers. Minerva Chir 2003;58:297-303.
-
(2003)
Minerva Chir
, vol.58
, pp. 297-303
-
-
Cheung, K.L.1
Robertson, F.R.2
-
47
-
-
32944479876
-
An intensive surveillance program detected a high incidence of hepatocellular carcinoma among hepatitis B virus carriers with abnormal α-fetoprotein levels or abdominal ultrasonography results
-
Mok TS, Yeo W, Yu S, et al. An intensive surveillance program detected a high incidence of hepatocellular carcinoma among hepatitis B virus carriers with abnormal α-fetoprotein levels or abdominal ultrasonography results. J Clin Oncol 2005;23:8041-7.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8041-8047
-
-
Mok, T.S.1
Yeo, W.2
Yu, S.3
-
48
-
-
30744468344
-
Associations of demographic and lifestyle characteristics with prostate-specific antigen (PSA) concentration and rate of PSA increase
-
Kristal AR, Chi C, Tangen CM, Goodman PJ, Etzioni R, Thompson IM. Associations of demographic and lifestyle characteristics with prostate-specific antigen (PSA) concentration and rate of PSA increase. Cancer 2006; 106:320-8.
-
(2006)
Cancer
, vol.106
, pp. 320-328
-
-
Kristal, A.R.1
Chi, C.2
Tangen, C.M.3
Goodman, P.J.4
Etzioni, R.5
Thompson, I.M.6
-
50
-
-
34247539036
-
-
Avalable from: http://www.cancer.gov/cancertopics/pdq/screening/ prostate/healthprofessional.
-
Avalable from
-
-
-
51
-
-
2442611898
-
Extracellular cAMP-dependent protein kinase (ECPKA) in melanoma
-
Kita T, Goydos J, Reitman E, et al. Extracellular cAMP-dependent protein kinase (ECPKA) in melanoma. Cancer Lett 2004;208:187-91.
-
(2004)
Cancer Lett
, vol.208
, pp. 187-191
-
-
Kita, T.1
Goydos, J.2
Reitman, E.3
|