An intensive surveillance program detected a high incidence of hepatocellular carcinoma among hepatitis B virus carriers with abnormal alpha-fetoprotein levels or abdominal ultrasonography results

Journal of Clinical Oncology

Volumn 23, Issue 31, 2005, Pages 8041-8047

  Mok, Tony S K ^a   Yeo, Winnie ^b   Yu, Simon ^b   Lai, Paul ^b   Chan, Henry L Y ^b   Chan, Anthony T C ^b   Lau, Joseph W Y ^b   Wong, Herman ^b   Leung, Nancy ^b   Hui, Edwin P ^b   Sung, Joseph ^b   Koh, Jane ^b   Mo, Frankie ^b   Zee, Benny ^b   Johnson, Philip J ^b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN; IODINATED POPPYSEED OIL; HEPATITIS B SURFACE ANTIGEN;

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER INCIDENCE; CANCER SCREENING; CANCER SIZE; CANCER SURGERY; CANCER SURVIVAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; ECHOGRAPHY; FEMALE; FOLLOW UP; HEALTH SURVEY; HEPATITIS B VIRUS; HUMAN; INTENSIVE CARE; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MEDICAL EDUCATION; PRIORITY JOURNAL; VIRUS CARRIER; ABDOMEN; BLOOD; HEPATITIS B; INCIDENCE; LIVER TUMOR; METABOLISM; MIDDLE AGED; PATHOGENICITY; SURVIVAL RATE; VIROLOGY;

ABDOMEN; ADULT; AGED; ALPHA-FETOPROTEINS; CARCINOMA, HEPATOCELLULAR; FEMALE; HEPATITIS B; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HUMANS; INCIDENCE; LIVER NEOPLASMS; MALE; MIDDLE AGED; POPULATION SURVEILLANCE; SURVIVAL RATE;

EID: 32944479876     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2005.01.9927     Document Type: Article

References (24)

1. El-Serag HB: Hepatocellular carcinoma: An epidemiologic view. J Clin Gastroenterol 35:S72-S78, 2002 (suppl 2)
2. Mericanc I, Guan R, Amarapuka D, et al: Chronic hepatitis B virus infection in Asian countries. J Gastroenterol Hepatol 15:1356-1361, 2000
3. El-Serag HB, Davila JA, Petersen NJ, et al: The continuing increase in the incidence of hepatocellular carcinoma in the United States: An update. Ann Intern Med 18:817-823, 2003
4. [Erratum: Ann Intern Med 140:151, 2004;
5. Summary for patients: Ann Intern Med 139:128, 2003]
6. Beasley RP, Hwang LY, Lin CC, et al: Hepatocellular carcinoma and hepatitis B virus: A prospective study of 22,707 men in Taiwan. Lancet 2(8256):1129-1133, 1981
7. Liaw YF, Tai DI, Chu CM, et al: Early detection of hepatocellular carcinoma in patients with chronic type B hepatitis: A prospective study. Gastroenterology 90:263-267, 1986
8. Chalasani N, Said A, Ness R, et al: Screening for hepatocellular carcinoma in patients with cirrhosis in the United States: Results of a national survey. Am J Gastroenterol 94:2224-2229, 1999
9. Yang B, Zhang B, Xu Y, et al: Prospective study of early detection for primary liver cancer. J Cancer Res Clin Oncol 123:357-360, 1997
10. Sherman M, Peltekian KM, Lee C: Screening for hepatocellular carcinoma in chronic carriers of hepatitis B virus: Incidence and prevalence of hepatocellular carcinoma in a North American urban population. Hepatology 22:432-438, 1995
11. McMahon BJ, Bulkow L, Harpster A, et al: Screening for hepatocellular carcinoma in Alaska natives infected with chronic hepatitis B: A 16-year population-based study. Hepatology 32:842-847, 2000
12. Palma LD: Diagnostic imaging and interventional therapy of hepatocellular carcinoma. Br J Radiol 71:808-818, 1998
13. Johnson PJ, Leung N, Cheng P, et al: "Hepatoma-specific" alphafetoprotein may permit preclinical diagnosis of malignant change in patients with chronic liver disease. Br J Cancer 75:236-240, 1997
14. Mok TS, Yu SC, Lee C, et al: False-negative rate of abdominal sonography for detection hepatocellular carcinoma in patients with hepatitis B and elevated serum alpha-fetoprotein level. AJR Am J Roentgenol 183:453-458, 2004
15. Ebara M, Ohto M, Shinagawa T, et al: Natural history of minute hepatocellular carcinoma smaller than three centimeters complicating cirrhosis: A study in 22 patients. Gastroenterology 90:289-298, 1986
16. Colombo M, de Franchis R, Del Ninno E, et al: Hepatocellular carcinoma in Italian patients with cirrhosis. N Engl J Med 325:675-680, 1991
17. Izzo F, Cremona F, Ruffolo F, et al: Outcome of 67 patients with hepatocellular cancer detected during screening of 1125 patients with chronic hepatitis. Ann Surg 227:513-518, 1998
18. Yuen MF, Cheng CC, Lauder IJ, et al: Early detection of hepatocellular carcinoma increases the chance of treatment: Hong Kong experience. Hepatology 31:330-335, 2000
19. Camma C, Schepis F, Orlando A, et al: Transarterial chemoembolization for unresectable hepatocellular carcinoma: Meta-analysis of randomized controlled trials. Radiology 224:47-54, 2002
20. Llovet JM, Bruix J: Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival. Hepatology 37:429-442, 2003
21. Sangiovanni A, Del Ninno E, Fasani P, et al: Increased survival of cirrhotic patients with a hepatocellular carcinoma detected during surveillance. Gastroenterology 126:1005-1014, 2004
22. Cillo U, Vitale A, Bassanello M, et al: Liver transplantation for the treatment of moderately or well-differentiated hepatocellular carcinoma. Ann Surg 239:150-159, 2004
23. Mazzaferro V, Regalia E, Doci R, et al: Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 334:693-699, 1996
24. Yao FY, Bass NM, Nikolai B, et al: Liver transplantation for hepatocellular carcinoma: Analysis of survival according to the intention-to-treat principle and dropout from the waiting list. Liver Transpl 8:873-883, 2002