메뉴 건너뛰기




Volumn 37, Issue 6, 2005, Pages 608-618

Radiosensitization by targeting radioresistance-related genes with protein kinase A inhibitor in radioresistant cancer cells

Author keywords

Cyclic AMP dependent protein kinases; Gene expression profiling; Gene expression regulation, neoplastic; Radiation

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DEOXYRIBONUCLEOPROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KU ANTIGEN; PROTEIN BAX; PROTEIN BCL 2;

EID: 31344452370     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2005.74     Document Type: Article
Times cited : (29)

References (38)
  • 1
    • 0037136673 scopus 로고    scopus 로고
    • The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit
    • Ader I, Muller C, Bonnet J, Favre G, Cohen-Jonathan E, Salles B, Toulas C. The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit. Oncogene 2002;21:6471-9
    • (2002) Oncogene , vol.21 , pp. 6471-6479
    • Ader, I.1    Muller, C.2    Bonnet, J.3    Favre, G.4    Cohen-Jonathan, E.5    Salles, B.6    Toulas, C.7
  • 2
    • 0142025259 scopus 로고    scopus 로고
    • Interactive competition between homologous recombination and non-homologous end joining
    • Allen C, Halbrook J, Nickoloff JA. Interactive competition between homologous recombination and non-homologous end joining. Mol Cancer Res 2003;1:913-20
    • (2003) Mol Cancer Res , vol.1 , pp. 913-920
    • Allen, C.1    Halbrook, J.2    Nickoloff, J.A.3
  • 3
    • 0842346433 scopus 로고    scopus 로고
    • Activation of stress-responsive promoters by ionizing radiation for deployment in targeted gene therapy
    • Amst
    • Chastel C, Jiricny J, Jaussi R. Activation of stress-responsive promoters by ionizing radiation for deployment in targeted gene therapy. DNA Repair (Amst) 2004;3:201-15
    • (2004) DNA Repair , vol.3 , pp. 201-215
    • Chastel, C.1    Jiricny, J.2    Jaussi, R.3
  • 4
    • 0036174013 scopus 로고    scopus 로고
    • Activation of nuclear factor kappaB in radioresistance of TP53-inactive human keratinocytes
    • Chen X, Shen B, Xia L, Khaletzkiy A, Chu D, Wong JY, Li JJ. Activation of nuclear factor kappaB in radioresistance of TP53-inactive human keratinocytes. Cancer Res 2002;62:1213-21
    • (2002) Cancer Res , vol.62 , pp. 1213-1221
    • Chen, X.1    Shen, B.2    Xia, L.3    Khaletzkiy, A.4    Chu, D.5    Wong, J.Y.6    Li, J.J.7
  • 5
  • 6
    • 5644283296 scopus 로고    scopus 로고
    • Role of chemopreventive agents in cancer therapy
    • Dorai T, Aggarwal BB. Role of chemopreventive agents in cancer therapy. Cancer Lett 2004;215:129-40
    • (2004) Cancer Lett , vol.215 , pp. 129-140
    • Dorai, T.1    Aggarwal, B.B.2
  • 8
    • 0028930725 scopus 로고
    • Protein kinase A inhibitors enhance radiation-induced apoptosis
    • Findik D, Song Q, Hidaka H, Lavin M. Protein kinase A inhibitors enhance radiation-induced apoptosis. J Cell Biochem 1995;57:12-21
    • (1995) J Cell Biochem , vol.57 , pp. 12-21
    • Findik, D.1    Song, Q.2    Hidaka, H.3    Lavin, M.4
  • 12
    • 1642478198 scopus 로고    scopus 로고
    • Didox (a novel ribonucleotide reductase inhibitor) overcomes Bcl-2 mediated radiation resistance in prostate cancer cell line PC-3
    • Inayat MS, Chendil D, Mohiuddin M, Elford HL, Gallicchio VS, Ahmed MM. Didox (a novel ribonucleotide reductase inhibitor) overcomes Bcl-2 mediated radiation resistance in prostate cancer cell line PC-3. Cancer Biol Ther 2002;1:539-45
    • (2002) Cancer Biol Ther , vol.1 , pp. 539-545
    • Inayat, M.S.1    Chendil, D.2    Mohiuddin, M.3    Elford, H.L.4    Gallicchio, V.S.5    Ahmed, M.M.6
  • 13
    • 0036261707 scopus 로고    scopus 로고
    • Sensing and repairing DNA double-strand breaks
    • Jackson SP. Sensing and repairing DNA double-strand breaks. Carcinogenesis 2002;23;687-96
    • (2002) Carcinogenesis , vol.23 , pp. 687-696
    • Jackson, S.P.1
  • 14
    • 1642422855 scopus 로고    scopus 로고
    • Alteration of gene expression during radiation-induced resistance and tumorigenesis in NIH3T3 cells revealed by cDNA microarrays: Involvement of MDM2 and CDC25B
    • Kang CM, Cho HN, Ahn JM, Lee SS, Jeoung DI, Cho CK, Bae S, Lee SJ, Lee YS. Alteration of gene expression during radiation-induced resistance and tumorigenesis in NIH3T3 cells revealed by cDNA microarrays: involvement of MDM2 and CDC25B. Carcinogenesis 2004;25:123-32
    • (2004) Carcinogenesis , vol.25 , pp. 123-132
    • Kang, C.M.1    Cho, H.N.2    Ahn, J.M.3    Lee, S.S.4    Jeoung, D.I.5    Cho, C.K.6    Bae, S.7    Lee, S.J.8    Lee, Y.S.9
  • 15
    • 0033739354 scopus 로고    scopus 로고
    • Potentiation of chemosensitivity in multidrug-resistant human leukemia CEM cells by inhibition of DNA-dependent protein kinase using wortmannin
    • Kim SH, Um JH, Kim DW, Kwon BH, Kim DW, Chung BS, Kang CD. Potentiation of chemosensitivity in multidrug-resistant human leukemia CEM cells by inhibition of DNA-dependent protein kinase using wortmannin. Leuk Res 2000;24:917-25
    • (2000) Leuk Res , vol.24 , pp. 917-925
    • Kim, S.H.1    Um, J.H.2    Kim, D.W.3    Kwon, B.H.4    Kim, D.W.5    Chung, B.S.6    Kang, C.D.7
  • 16
    • 2442710431 scopus 로고    scopus 로고
    • Involvement of ROS and JNK1 in selenite-induced apoptosis in Chang liver cells
    • Kim YS, Jhon DY, Lee KY. Involvement of ROS and JNK1 in selenite-induced apoptosis in Chang liver cells. Exp Mol Med 2004;36:157-64
    • (2004) Exp Mol Med , vol.36 , pp. 157-164
    • Kim, Y.S.1    Jhon, D.Y.2    Lee, K.Y.3
  • 17
    • 2942579657 scopus 로고    scopus 로고
    • Changes in gene expression associated with stable drug and radiation resistance in small cell lung cancer cells are similar to those caused by a single X-ray dose
    • Henness S, Davey MW, Harvie RM, Banyer J, Wasinger V, Corthals G, Davey RA. Changes in gene expression associated with stable drug and radiation resistance in small cell lung cancer cells are similar to those caused by a single X-ray dose. Radiat Res 2004;16:495-503
    • (2004) Radiat Res , vol.16 , pp. 495-503
    • Henness, S.1    Davey, M.W.2    Harvie, R.M.3    Banyer, J.4    Wasinger, V.5    Corthals, G.6    Davey, R.A.7
  • 19
    • 18744388261 scopus 로고    scopus 로고
    • Evidence for the involvement of DNA-dependent protein kinase in the phenomena of low dose hyper-radiosensitivity and increased radioresistance
    • Marples B, Cann NE, Mitchell CR, Johnston PJ, Joiner MC. Evidence for the involvement of DNA-dependent protein kinase in the phenomena of low dose hyper-radiosensitivity and increased radioresistance. Int J Radiat Biol 2002;78:1139-47
    • (2002) Int J Radiat Biol , vol.78 , pp. 1139-1147
    • Marples, B.1    Cann, N.E.2    Mitchell, C.R.3    Johnston, P.J.4    Joiner, M.C.5
  • 20
    • 0028800947 scopus 로고
    • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of bcl-2 and abl
    • Martin SJ, Reutelingaperger CP, McGahon AJ, Rader JA, van Schie RC, LaFace DM, Green DR. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of bcl-2 and abl. J Exp Med 1995;182:1545-56
    • (1995) J Exp Med , vol.182 , pp. 1545-1556
    • Martin, S.J.1    Reutelingaperger, C.P.2    McGahon, A.J.3    Rader, J.A.4    Van Schie, R.C.5    LaFace, D.M.6    Green, D.R.7
  • 21
    • 0031550257 scopus 로고    scopus 로고
    • Evidence supporting a signal transduction pathway leading to the radiation-resistant phenotype in human tumor cells
    • Pirollo KF, Hao Z, Rait A, Ho CW, Chang EH. Evidence supporting a signal transduction pathway leading to the radiation-resistant phenotype in human tumor cells. Biochem Biophys Res Commun 1997;230:196-201
    • (1997) Biochem Biophys Res Commun , vol.230 , pp. 196-201
    • Pirollo, K.F.1    Hao, Z.2    Rait, A.3    Ho, C.W.4    Chang, E.H.5
  • 22
    • 0032966188 scopus 로고    scopus 로고
    • The molecular and cellular basis of radiosensitivity: Implications for understanding how normal tissues and tumors respond to therapeutic radiation
    • Rosen EM, Fan S, Rockwell S, Goldberg ID. The molecular and cellular basis of radiosensitivity: implications for understanding how normal tissues and tumors respond to therapeutic radiation. Cancer Invest 1999;17:56-72
    • (1999) Cancer Invest , vol.17 , pp. 56-72
    • Rosen, E.M.1    Fan, S.2    Rockwell, S.3    Goldberg, I.D.4
  • 23
    • 0031879187 scopus 로고    scopus 로고
    • Increased expression of DNA-dependent protein kinase confers resistance to adriamycin
    • Shen H, Schultz M, Kruh GD, Tew KD. Increased expression of DNA-dependent protein kinase confers resistance to adriamycin. Biochim Biophys Acta 1998;1381:131-8
    • (1998) Biochim Biophys Acta , vol.1381 , pp. 131-138
    • Shen, H.1    Schultz, M.2    Kruh, G.D.3    Tew, K.D.4
  • 24
    • 0033560796 scopus 로고    scopus 로고
    • The DNA-dependent protein kinase
    • Smith GC, Jackson SP. The DNA-dependent protein kinase. Genes Dev 1999;13:916-34
    • (1999) Genes Dev , vol.13 , pp. 916-934
    • Smith, G.C.1    Jackson, S.P.2
  • 25
    • 3042773987 scopus 로고    scopus 로고
    • Gene expression profiling after irradiation: Clues to understanding acute and persistent responses?
    • Snyder AR, Morgan WF. Gene expression profiling after irradiation: clues to understanding acute and persistent responses ? Cancer Metastasis Rev 2004;23:259-68
    • (2004) Cancer Metastasis Rev , vol.23 , pp. 259-268
    • Snyder, A.R.1    Morgan, W.F.2
  • 26
    • 21644480047 scopus 로고    scopus 로고
    • Activation of the phosphatidylinositol 3-kinase/Akt pathway prevents radiation-induced apoptosis in breast cancer cells
    • Soderlund K, Perez-Tenorio G, Stal O. Activation of the phosphatidylinositol 3-kinase/Akt pathway prevents radiation-induced apoptosis in breast cancer cells. Int J Oncol 2005;26:25-32
    • (2005) Int J Oncol , vol.26 , pp. 25-32
    • Soderlund, K.1    Perez-Tenorio, G.2    Stal, O.3
  • 28
    • 1642539107 scopus 로고    scopus 로고
    • Enhanced radiosensitization and chemosensitization in NF-kappaB-suppressed human oral cancer cells via the inhibition of gamma-irradiation- and 5-FU-induced production of IL-6 and IL-8
    • Tamatani T, Azuma M, Ashida Y, Motegi K, Takashima R, Harada K, Kawaguchi S, Sato M. Enhanced radiosensitization and chemosensitization in NF-kappaB-suppressed human oral cancer cells via the inhibition of gamma-irradiation- and 5-FU-induced production of IL-6 and IL-8. Int J Cancer 2004;108:912-21
    • (2004) Int J Cancer , vol.108 , pp. 912-921
    • Tamatani, T.1    Azuma, M.2    Ashida, Y.3    Motegi, K.4    Takashima, R.5    Harada, K.6    Kawaguchi, S.7    Sato, M.8
  • 30
    • 0036297650 scopus 로고    scopus 로고
    • Protein kinase A as target for novel integrated strategies of cancer therapy
    • Tortora G, Ciardiello F. Protein kinase A as target for novel integrated strategies of cancer therapy. Ann N Y Acad Sci 2002;968:139-47
    • (2002) Ann N Y Acad Sci , vol.968 , pp. 139-147
    • Tortora, G.1    Ciardiello, F.2
  • 31
    • 1342310966 scopus 로고    scopus 로고
    • Antisense targeting protein kinase A type I as a drug for integrated strategies of cancer therapy
    • Tortora G, Ciardiello F. Antisense targeting protein kinase A type I as a drug for integrated strategies of cancer therapy. Ann N Y Acad Sci 2003;1002:236-43
    • (2003) Ann N Y Acad Sci , vol.1002 , pp. 236-243
    • Tortora, G.1    Ciardiello, F.2
  • 32
    • 0035921734 scopus 로고    scopus 로고
    • Increased and correlated nuclear factor-kappa B and Ku autoantigen activities are associated with development of multidrug resistance
    • Um JH, Kang CD, Lee BG, Kim DW, Chung BS, Kim SH. Increased and correlated nuclear factor-kappa B and Ku autoantigen activities are associated with development of multidrug resistance. Oncogene 2001;20:6048-56
    • (2001) Oncogene , vol.20 , pp. 6048-6056
    • Um, J.H.1    Kang, C.D.2    Lee, B.G.3    Kim, D.W.4    Chung, B.S.5    Kim, S.H.6
  • 33
    • 3242776224 scopus 로고    scopus 로고
    • Association of DNA-dependent protein kinase with hypoxia inducible factor-1 and its implication in resistance to anticancer drugs in hypoxic tumor cells
    • Um JH, Kang CD, Bae JH, Shin GG, Kim MJ, Kim DW, Kim DW, Chung BS, Kim SH. Association of DNA-dependent protein kinase with hypoxia inducible factor-1 and its implication in resistance to anticancer drugs in hypoxic tumor cells. EXP Mol Med 2004;36:233-42
    • (2004) EXP Mol Med , vol.36 , pp. 233-242
    • Um, J.H.1    Kang, C.D.2    Bae, J.H.3    Shin, G.G.4    Kim, M.J.5    Kim, D.W.6    Kim, D.W.7    Chung, B.S.8    Kim, S.H.9
  • 34
    • 10044229261 scopus 로고    scopus 로고
    • Relationship between antiapoptotic molecules and metastatic potency and the involvement of DNA-dependent protein kinase in the chemosensitization of metastatic human cancer cells by epidermal growth factor receptor blockade
    • Um JH, Kwon JK, Kang CD, Kim MJ, Ju DS, Bae JH, Kim DW, Chung BS, Kim SH. Relationship between antiapoptotic molecules and metastatic potency and the involvement of DNA-dependent protein kinase in the chemosensitization of metastatic human cancer cells by epidermal growth factor receptor blockade. J Pharmacol Exp Ther 2004;311:1062-70
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 1062-1070
    • Um, J.H.1    Kwon, J.K.2    Kang, C.D.3    Kim, M.J.4    Ju, D.S.5    Bae, J.H.6    Kim, D.W.7    Chung, B.S.8    Kim, S.H.9
  • 35
    • 0036145471 scopus 로고    scopus 로고
    • Identification of radiation-responsive genes in vitro using a gene trap strategy predicts for modulation of expression by radiation in vivo
    • Vallis KA, Chen Z, Stanford WL, Yu M, Hill RP, Bernstein A. Identification of radiation-responsive genes in vitro using a gene trap strategy predicts for modulation of expression by radiation in vivo. Radiat Res 2002;157:8-18
    • (2002) Radiat Res , vol.157 , pp. 8-18
    • Vallis, K.A.1    Chen, Z.2    Stanford, W.L.3    Yu, M.4    Hill, R.P.5    Bernstein, A.6
  • 36
    • 17344392896 scopus 로고    scopus 로고
    • Cell cycle alteration, apoptosis and response of leukemic cell lines to gamma radiation with high- and low-dose rate
    • Vavrova J, Rezacova M, Vokurkova D, Psutka J. Cell cycle alteration, apoptosis and response of leukemic cell lines to gamma radiation with high- and low-dose rate. Physiol Res 2004; 53:335-42
    • (2004) Physiol Res , vol.53 , pp. 335-342
    • Vavrova, J.1    Rezacova, M.2    Vokurkova, D.3    Psutka, J.4
  • 38
    • 0031763944 scopus 로고    scopus 로고
    • Increased expression of human DNA repair genes, XRCC1, XRCC3 and RAD51, in radioresistant human KB carcinoma cell line N10
    • Yanagisawa T, Urade M, Yamamoto Y, Furuyama J. Increased expression of human DNA repair genes, XRCC1, XRCC3 and RAD51, in radioresistant human KB carcinoma cell line N10. Oral Oncol 1998;34:524-8
    • (1998) Oral Oncol , vol.34 , pp. 524-528
    • Yanagisawa, T.1    Urade, M.2    Yamamoto, Y.3    Furuyama, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.