-
1
-
-
0345304849
-
Genomic organization and expression of parkin in Drosophila melanogaster
-
Bae Y.J., Park K.S., and Kang S.J. Genomic organization and expression of parkin in Drosophila melanogaster. Exp. Mol. Med. 35 (2003) 393-402
-
(2003)
Exp. Mol. Med.
, vol.35
, pp. 393-402
-
-
Bae, Y.J.1
Park, K.S.2
Kang, S.J.3
-
2
-
-
1542381057
-
Cell cycle regulation of neuronal apoptosis in development and disease
-
Becker E.B., and Bonni A. Cell cycle regulation of neuronal apoptosis in development and disease. Prog. Neurobiol. 72 (2004) 1-25
-
(2004)
Prog. Neurobiol.
, vol.72
, pp. 1-25
-
-
Becker, E.B.1
Bonni, A.2
-
3
-
-
0033363646
-
The septin CDCrel-1 binds syntaxin and inhibits exocytosis
-
Beites CL., Xie H., Bowser R., and Trimble WS. The septin CDCrel-1 binds syntaxin and inhibits exocytosis. Nat. Neurosci. 2 (1999) 434-439
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 434-439
-
-
Beites, CL.1
Xie, H.2
Bowser, R.3
Trimble, WS.4
-
4
-
-
0037157107
-
Human septin-septin interaction: CDCrel-1 partners with KIAA0202
-
Blaser S., Jersch K., Hainmann I., Wunderle D., Zgaga-Griesz A., Busse A., and Zieger B. Human septin-septin interaction: CDCrel-1 partners with KIAA0202. FEBS Lett. 519 (2002) 169-172
-
(2002)
FEBS Lett.
, vol.519
, pp. 169-172
-
-
Blaser, S.1
Jersch, K.2
Hainmann, I.3
Wunderle, D.4
Zgaga-Griesz, A.5
Busse, A.6
Zieger, B.7
-
5
-
-
0030757229
-
The synaptic protein syntaxin1 is required for cellularization of Drosophila embryos
-
Burgess R.W., Deitcher D.L., and Schwarz T.L. The synaptic protein syntaxin1 is required for cellularization of Drosophila embryos. J. Cell Biol. 138 (1997) 861-875
-
(1997)
J. Cell Biol.
, vol.138
, pp. 861-875
-
-
Burgess, R.W.1
Deitcher, D.L.2
Schwarz, T.L.3
-
6
-
-
22544458436
-
Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila
-
Cha G.H., Kim S., Park J., Lee E., Kim M., Lee S.B., Kim J.M., Chung J., and Cho K.S. Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila. Proc. Natl. Acad. Sci. USA 102 (2005) 10345-10350
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 10345-10350
-
-
Cha, G.H.1
Kim, S.2
Park, J.3
Lee, E.4
Kim, M.5
Lee, S.B.6
Kim, J.M.7
Chung, J.8
Cho, K.S.9
-
7
-
-
12144290241
-
SEPT5_v2 is a Parkin-binding protein
-
Choi P., Snyder H., Petrucelli L., Theisler C., Chong M., Zhang Y., Lim K., Chung KK., Kehoe K., D' Adamio L., Lee J.M., Cochran E., Bowser R., Dawson T.M., and Wolozin B. SEPT5_v2 is a Parkin-binding protein. Brain Res. Mol. Brain Res. 117 (2003) 179-189
-
(2003)
Brain Res. Mol. Brain Res.
, vol.117
, pp. 179-189
-
-
Choi, P.1
Snyder, H.2
Petrucelli, L.3
Theisler, C.4
Chong, M.5
Zhang, Y.6
Lim, K.7
Chung, KK.8
Kehoe, K.9
D' Adamio, L.10
Lee, J.M.11
Cochran, E.12
Bowser, R.13
Dawson, T.M.14
Wolozin, B.15
-
8
-
-
0034776095
-
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease
-
Chung KK., Zhang Y., Lim KL., Tanaka Y., Huang H., Gao J., Ross CA., Dawson VL., and Dawson TM. Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nat. Med. 7 (2001) 1144-1150
-
(2001)
Nat. Med.
, vol.7
, pp. 1144-1150
-
-
Chung, KK.1
Zhang, Y.2
Lim, KL.3
Tanaka, Y.4
Huang, H.5
Gao, J.6
Ross, CA.7
Dawson, VL.8
Dawson, TM.9
-
10
-
-
0033279836
-
SCF and Cullin/Ring H2-based ubiquitin ligases
-
Deshaies R.J. SCF and Cullin/Ring H2-based ubiquitin ligases. Annu. Rev. Cell Dev. Biol. 15 (1999) 435-467
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 435-467
-
-
Deshaies, R.J.1
-
11
-
-
0142059791
-
Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the Parkin target protein, CDCrel-1
-
Dong Z., Ferger B., Paterna J., Vogel D., Furler S., Osinde M., Feldon J., and Bueler H. Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the Parkin target protein, CDCrel-1. Proc. Natl. Acad. Sci. USA 100 (2003) 12438-12443
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12438-12443
-
-
Dong, Z.1
Ferger, B.2
Paterna, J.3
Vogel, D.4
Furler, S.5
Osinde, M.6
Feldon, J.7
Bueler, H.8
-
12
-
-
0028820410
-
Localization and possible functions of Drosophila septins
-
Fares H., Peifer M., and Pringle J.R. Localization and possible functions of Drosophila septins. Mol. Biol. Cell 6 (1995) 1843-1859
-
(1995)
Mol. Biol. Cell
, vol.6
, pp. 1843-1859
-
-
Fares, H.1
Peifer, M.2
Pringle, J.R.3
-
13
-
-
0038121031
-
The cellular protein level of parkin is regulated by its ubiqtuin-like domain
-
Finney N., Walther F., Mantel P., Stauffer D., Rovelli G., and Dev K. The cellular protein level of parkin is regulated by its ubiqtuin-like domain. J. Biol. Chem. 278 (2003) 16054-16058
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 16054-16058
-
-
Finney, N.1
Walther, F.2
Mantel, P.3
Stauffer, D.4
Rovelli, G.5
Dev, K.6
-
14
-
-
0035959931
-
Parkin and the molecular pathways of Parkinson's disease
-
Giasson B.I., and Lee V.M. Parkin and the molecular pathways of Parkinson's disease. Neuron 31 (2001) 885-888
-
(2001)
Neuron
, vol.31
, pp. 885-888
-
-
Giasson, B.I.1
Lee, V.M.2
-
15
-
-
0037386532
-
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
-
Greene J.C., Whitworth A.J., Kuo I., Andrews L.A., Feany M.B., and Pallanck L.J. Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc. Natl. Acad. Sci. USA 100 (2003) 4078-4083
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4078-4083
-
-
Greene, J.C.1
Whitworth, A.J.2
Kuo, I.3
Andrews, L.A.4
Feany, M.B.5
Pallanck, L.J.6
-
16
-
-
7944228563
-
The pathobiology of the septin gene family
-
Hall P.A., and Russell S.E. The pathobiology of the septin gene family. J. Pathol. 204 (2004) 489-505
-
(2004)
J. Pathol.
, vol.204
, pp. 489-505
-
-
Hall, P.A.1
Russell, S.E.2
-
17
-
-
0002344864
-
Skipping into the E2F1-destruction pathway
-
Harper J.W., and Elledge S.J. Skipping into the E2F1-destruction pathway. Nat. Cell Biol. 1 (1999) E5-E7
-
(1999)
Nat. Cell Biol.
, vol.1
-
-
Harper, J.W.1
Elledge, S.J.2
-
18
-
-
4344681293
-
Pathogenetic mechanisms of parkin in Parkinson's disease
-
Hattori N., and Mizuno Y. Pathogenetic mechanisms of parkin in Parkinson's disease. Lancet 364 (2004) 722-724
-
(2004)
Lancet
, vol.364
, pp. 722-724
-
-
Hattori, N.1
Mizuno, Y.2
-
19
-
-
2642516493
-
Parkin counteracts symptoms in a Drosophila model of Parkinson's disease
-
Haywood A.F., and Staveley B.E. Parkin counteracts symptoms in a Drosophila model of Parkinson's disease. BMC Neurosci. 5 (2004) 14-19
-
(2004)
BMC Neurosci.
, vol.5
, pp. 14-19
-
-
Haywood, A.F.1
Staveley, B.E.2
-
20
-
-
33747832846
-
Mutant alpha-synuclein-induced degeneration is reduced by parkin in a fly model of Parkinson's disease
-
Haywood A.F., and Staveley B.E. Mutant alpha-synuclein-induced degeneration is reduced by parkin in a fly model of Parkinson's disease. Genome 49 (2006) 505-510
-
(2006)
Genome
, vol.49
, pp. 505-510
-
-
Haywood, A.F.1
Staveley, B.E.2
-
21
-
-
0141995596
-
The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI
-
Huynh D.P., Scoles D.R., Nguyen D., and Pulst S.M. The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI. Hum. Mol. Genet. 12 (2003) 2587-2597
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 2587-2597
-
-
Huynh, D.P.1
Scoles, D.R.2
Nguyen, D.3
Pulst, S.M.4
-
22
-
-
0035967883
-
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
-
Imai Y., Soda M., Inoue H., Hattori N., Mizuno Y., and Takahashi R. An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell 105 (2001) 891-902
-
(2001)
Cell
, vol.105
, pp. 891-902
-
-
Imai, Y.1
Soda, M.2
Inoue, H.3
Hattori, N.4
Mizuno, Y.5
Takahashi, R.6
-
23
-
-
0033536637
-
The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase
-
Joazeiro C.A., Wing S.S., Huang H., Leverson J.D., Hunter T., and Liu Y.C. The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase. Science 286 (1999) 309-312
-
(1999)
Science
, vol.286
, pp. 309-312
-
-
Joazeiro, C.A.1
Wing, S.S.2
Huang, H.3
Leverson, J.D.4
Hunter, T.5
Liu, Y.C.6
-
24
-
-
0034927814
-
Apoptotic signaling in dopamine-induced cell death: the role of oxidative stress, p38 mitogen-activated protein kinase, cytochrome c and caspases
-
Junn E., and Mouradian M.M. Apoptotic signaling in dopamine-induced cell death: the role of oxidative stress, p38 mitogen-activated protein kinase, cytochrome c and caspases. J. Neurochem. 78 (2001) 374-383
-
(2001)
J. Neurochem.
, vol.78
, pp. 374-383
-
-
Junn, E.1
Mouradian, M.M.2
-
25
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T., Asakawa S., Hattori N., Matsumine H., Yamamura Y., Minoshima S., Yokochi M., Mizuno Y., and Shimizu N. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392 (1998) 605-608
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
26
-
-
0342368772
-
Association between early-onset Parkinson's disease and mutations in the parkin gene. French Parkinson's Disease Genetics Study Group
-
Lücking C.B., Durr A., Bonifati V., Vaughan J., De Michele G., Gasser T., Harhangi B.S., Meco G., Denefle P., Wood N.W., Agid Y., and Brice A. Association between early-onset Parkinson's disease and mutations in the parkin gene. French Parkinson's Disease Genetics Study Group. N. Engl. J. Med. 342 (2000) 1560-1567
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 1560-1567
-
-
Lücking, C.B.1
Durr, A.2
Bonifati, V.3
Vaughan, J.4
De Michele, G.5
Gasser, T.6
Harhangi, B.S.7
Meco, G.8
Denefle, P.9
Wood, N.W.10
Agid, Y.11
Brice, A.12
-
27
-
-
12444281013
-
Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease
-
Marx F.P., Holzmann C., Strauss K.M., Li L., Eberhardt O., Gerhardt E., Cookson M.R., Hernandez D., Farrer M.J., Kachergus J., Engelender S., Ross C.A., Berger K., Schols L., Schulz J.B., Riess O., and Kruger R. Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease. Hum. Mol. Genet. 12 (2003) 1223-1231
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 1223-1231
-
-
Marx, F.P.1
Holzmann, C.2
Strauss, K.M.3
Li, L.4
Eberhardt, O.5
Gerhardt, E.6
Cookson, M.R.7
Hernandez, D.8
Farrer, M.J.9
Kachergus, J.10
Engelender, S.11
Ross, C.A.12
Berger, K.13
Schols, L.14
Schulz, J.B.15
Riess, O.16
Kruger, R.17
-
28
-
-
0032961592
-
Characterization of a novel gene, PNUTL2, on human chromosome 17q22-q23 and its exclusion as the Meckel syndrome gene
-
Paavola P., Horelli-Kuitunen N., Palotie A., and Peltonen L. Characterization of a novel gene, PNUTL2, on human chromosome 17q22-q23 and its exclusion as the Meckel syndrome gene. Genomics 55 (1999) 122-125
-
(1999)
Genomics
, vol.55
, pp. 122-125
-
-
Paavola, P.1
Horelli-Kuitunen, N.2
Palotie, A.3
Peltonen, L.4
-
29
-
-
0035725833
-
Dopamine induces phenotypic differentiation or apoptosis in a dose-dependent fashion: involvement of the dopamine transporter and p53
-
Porat S., Premkumar A., and Simantov R. Dopamine induces phenotypic differentiation or apoptosis in a dose-dependent fashion: involvement of the dopamine transporter and p53. Dev. Neurosci. 23 (2001) 432-440
-
(2001)
Dev. Neurosci.
, vol.23
, pp. 432-440
-
-
Porat, S.1
Premkumar, A.2
Simantov, R.3
-
30
-
-
0037738525
-
Parkin binds to alpha/beta tubulin and increases their ubiquitination and degradation
-
Ren Y., Zhao J., and Feng J. Parkin binds to alpha/beta tubulin and increases their ubiquitination and degradation. J. Neurosci. 23 (2003) 3316-3324
-
(2003)
J. Neurosci.
, vol.23
, pp. 3316-3324
-
-
Ren, Y.1
Zhao, J.2
Feng, J.3
-
31
-
-
0033933048
-
Familial Parkinson disease gene product, Parkin, is a ubiquitin-protein ligase
-
Shimura H., Hattori N., Kubo S., Mizuno Y., Asakawa S., Minoshima S., Shimizu N., Iwai K., Chiba T., Tanaka K., and Suzuki T. Familial Parkinson disease gene product, Parkin, is a ubiquitin-protein ligase. Nat. Genet. 25 (2000) 302-305
-
(2000)
Nat. Genet.
, vol.25
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
Shimizu, N.7
Iwai, K.8
Chiba, T.9
Tanaka, K.10
Suzuki, T.11
-
32
-
-
0035854437
-
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease
-
Shimura H., Schlossmacher M.G., Hattori N., Frosch M.P., Trockenbacher A., Schneider R., Mizuno Y., Kosik K.S., and Selkoe D.J. Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease. Science 293 (2001) 263-269
-
(2001)
Science
, vol.293
, pp. 263-269
-
-
Shimura, H.1
Schlossmacher, M.G.2
Hattori, N.3
Frosch, M.P.4
Trockenbacher, A.5
Schneider, R.6
Mizuno, Y.7
Kosik, K.S.8
Selkoe, D.J.9
-
33
-
-
0030614656
-
Induction of mitosis-related genes during dopamine-triggered apoptosis in sympathetic neurons
-
Shirvan A., Ziv I., Barzilai A., Djaldeti R., Zilkh-Falb R., Michlin T., and Melamed E. Induction of mitosis-related genes during dopamine-triggered apoptosis in sympathetic neurons. J. Neural Transm. Suppl. 50 (1997) 67-78
-
(1997)
J. Neural Transm. Suppl.
, vol.50
, pp. 67-78
-
-
Shirvan, A.1
Ziv, I.2
Barzilai, A.3
Djaldeti, R.4
Zilkh-Falb, R.5
Michlin, T.6
Melamed, E.7
-
34
-
-
33644862373
-
Drosophila models pioneer a new approach to drug discovery for Parkinson's disease
-
Whitworth A.J., Wes P.D., and Pallanck L.J. Drosophila models pioneer a new approach to drug discovery for Parkinson's disease. Drug Discov. Today 11 (2006) 119-126
-
(2006)
Drug Discov. Today
, vol.11
, pp. 119-126
-
-
Whitworth, A.J.1
Wes, P.D.2
Pallanck, L.J.3
-
35
-
-
0033485869
-
The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain
-
Xie Y., and Varshavsky A. The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain. EMBO J. 18 (1999) 6832-6844
-
(1999)
EMBO J.
, vol.18
, pp. 6832-6844
-
-
Xie, Y.1
Varshavsky, A.2
-
36
-
-
7244262110
-
Septin 3 (G-septin) is a developmentally regulated phosphoprotein enriched in presynaptic nerve terminals
-
Xue J., Tsang C.W., Gai W.P., Malladi C.S., Trimble W.S., Rostas J.A., and Robinson P.J. Septin 3 (G-septin) is a developmentally regulated phosphoprotein enriched in presynaptic nerve terminals. J. Neurochem. 91 (2004) 579-590
-
(2004)
J. Neurochem.
, vol.91
, pp. 579-590
-
-
Xue, J.1
Tsang, C.W.2
Gai, W.P.3
Malladi, C.S.4
Trimble, W.S.5
Rostas, J.A.6
Robinson, P.J.7
-
37
-
-
0037468831
-
Parkin suppresses dopaminergic neuron-selective neurotoxity induced by Pael-R in Drosophila
-
Yang Y., Nishimura I., Imai Y., Takahashi R., and Lu B. Parkin suppresses dopaminergic neuron-selective neurotoxity induced by Pael-R in Drosophila. Neuron 37 (2003) 911-924
-
(2003)
Neuron
, vol.37
, pp. 911-924
-
-
Yang, Y.1
Nishimura, I.2
Imai, Y.3
Takahashi, R.4
Lu, B.5
-
38
-
-
0034700158
-
Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
-
Zhang Y., Gao J., Chung K., Huang H., Dawson V.L., and Dawson T.M. Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. Proc. Natl. Acad. Sci. USA 97 (2000) 13354-13359
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13354-13359
-
-
Zhang, Y.1
Gao, J.2
Chung, K.3
Huang, H.4
Dawson, V.L.5
Dawson, T.M.6
|