Does topoisomerase II specifically recognize and cleave hairpins, cruciforms and crossovers of DNA?

Biochimie

Volumn 89, Issue 4, 2007, Pages 508-515

  René, Brigitte ^a   Fermandjian, Serge ^a   Mauffret, Olivier ^a  

^a Ecole Normale Superieure de Cachan   (France)

Author keywords

Crossovers; DNA cruciforms; DNA topoisomerase type II; Hairpins; Nucleic acid conformation; Substrate specificity

Indexed keywords

CRUCIFORM DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); ELLIPTICINE;

ARTICLE; CHIRALITY; DNA SEQUENCE; DNA STRUCTURE; DNA SUPERCOILING; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; GEOMETRY; HOLLIDAY JUNCTION; HUMAN; LITERATURE; NONHUMAN;

BINDING SITES; DNA; DNA TOPOISOMERASES, TYPE II; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

EID: 34247346622     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2007.02.011     Document Type: Article

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