Simplification of DNA topology below equilibrium values by type II topoisomerases

Science

Volumn 277, Issue 5326, 1997, Pages 690-693

  Rybenkov, Valentin V ^a   Ullsperger, Christian ^a   Vologodskii, Alexander V ^b   Cozzarelli, Nicholas R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA TOPOISOMERASE (ATP HYDROLYSING);

ARTICLE; DNA CONFORMATION; ENZYME SUBSTRATE COMPLEX; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN DNA BINDING;

ADENOSINE TRIPHOSPHATE; ANIMALS; DNA TOPOISOMERASE IV; DNA TOPOISOMERASES, TYPE II; DNA, CIRCULAR; DNA, SUPERHELICAL; DNA, VIRAL; DROSOPHILA MELANOGASTER; ESCHERICHIA COLI; HUMANS; HYDROLYSIS; MODELS, CHEMICAL; MYOVIRIDAE; NUCLEIC ACID CONFORMATION; SACCHAROMYCES CEREVISIAE; THERMODYNAMICS;

EUKARYOTA; PROKARYOTA;

EID: 0030758268     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.277.5326.690     Document Type: Article

References (29)

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29. We thank T. Hsieh for D. melanogaster topo II, K. Marians for E coli topo III, L. Shen for human topo II, J. Wang for Saccharomyces cerevisiae full-length and COOH-terminally truncated topo II, and I. Tinoco, J. Wang, and P. Wolynes for valuable discussions. Supported by NIH grants GM31657 to N.R.C. and GM54215 to A.V.V. and a Howard Hughes Medical Institute Predoctoral Fellowship to C.U.