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Volumn 100, Issue 5, 2007, Pages 316-322

Modulation of ERG channels by XE991

Author keywords

[No Author keywords available]

Indexed keywords

10,10 BIS(4 PYRIDINYLMETHYL) 9(10H) ANTHRACENONE; CHROMANOL 293B; LINOPIRIDINE; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL HERG; RETIGABINE; UNCLASSIFIED DRUG;

EID: 34247337214     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2007.00048.x     Document Type: Article
Times cited : (28)

References (45)
  • 1
    • 0034303612 scopus 로고    scopus 로고
    • Neuronal KCNQ potassium channels: Physiology and role in disease
    • Jentsch TJ. Neuronal KCNQ potassium channels: physiology and role in disease. Nat Rev Neurosci 2000 1 : 21 30.
    • (2000) Nat Rev Neurosci , vol.1 , pp. 21-30
    • Jentsch, T.J.1
  • 2
    • 29144529013 scopus 로고    scopus 로고
    • The KCNQ1 potassium channel: From gene to physiological function
    • Jespersen T, Grunnet M, Olesen SP. The KCNQ1 potassium channel: from gene to physiological function. Physiology 2005 20 : 408 16.
    • (2005) Physiology , vol.20 , pp. 408-16
    • Jespersen, T.1    Grunnet, M.2    Olesen, S.P.3
  • 3
    • 0034929557 scopus 로고    scopus 로고
    • KCNQ potassium channels: Physiology, pathophysiology, and pharmacology
    • Robbins J. KCNQ potassium channels: physiology, pathophysiology, and pharmacology. Pharmacol Ther 2001 90 : 1 19.
    • (2001) Pharmacol Ther , vol.90 , pp. 1-19
    • Robbins, J.1
  • 4
    • 0029952101 scopus 로고    scopus 로고
    • K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current
    • Barhanin J, Lesage F, Guillemare E, Fink M, Lazdunski M, Romey G. K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current. Nature 1996 384 : 78 80.
    • (1996) Nature , vol.384 , pp. 78-80
    • Barhanin, J.1    Lesage, F.2    Guillemare, E.3    Fink, M.4    Lazdunski, M.5    Romey, G.6
  • 5
    • 0029854263 scopus 로고    scopus 로고
    • Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel
    • Sanguinetti MC, Curran ME, Zou A et al. Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel. Nature 1996 384 : 80 3.
    • (1996) Nature , vol.384 , pp. 80-3
    • Sanguinetti, M.C.1    Curran, M.E.2    Zou, A.3
  • 6
    • 0018886033 scopus 로고
    • Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone
    • Brown DA, Adams PR. Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone. Nature 1980 283 : 673 6.
    • (1980) Nature , vol.283 , pp. 673-6
    • Brown, D.A.1    Adams, P.R.2
  • 7
    • 0032483972 scopus 로고    scopus 로고
    • KCNQ2 and KCNQ3 potassium channel subunits: Molecular correlates of the M-channel
    • Wang HS, Pan Z, Shi W et al. KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel. Science 1998 282 : 1890 3.
    • (1998) Science , vol.282 , pp. 1890-3
    • Wang, H.S.1    Pan, Z.2    Shi, W.3
  • 8
    • 27644446584 scopus 로고    scopus 로고
    • The KCNQ5 potassium channel from mouse: A broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes
    • Jensen HS, Callo K, Jespersen T, Jensen BS, Olesen SP. The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes. Brain Res Mol Brain Res 2005 139 : 52 62.
    • (2005) Brain Res Mol Brain Res , vol.139 , pp. 52-62
    • Jensen, H.S.1    Callo, K.2    Jespersen, T.3    Jensen, B.S.4    Olesen, S.P.5
  • 9
    • 0032773288 scopus 로고    scopus 로고
    • Separation of M-like current and ERG current in NG108-15 cells
    • Meves H, Schwarz JR, Wulfsen I. Separation of M-like current and ERG current in NG108-15 cells. Br J Pharmacol 1999 127 : 1213 23.
    • (1999) Br J Pharmacol , vol.127 , pp. 1213-23
    • Meves, H.1    Schwarz, J.R.2    Wulfsen, I.3
  • 10
    • 0033568873 scopus 로고    scopus 로고
    • Two types of K(+) channel subunit, ERG1 and KCNQ2/3, contribute to the M-like current in a mammalian neuronal cell
    • Selyanko AA, Hadley JK, Wood IC et al. Two types of K(+) channel subunit, ERG1 and KCNQ2/3, contribute to the M-like current in a mammalian neuronal cell. J Neurosci 1999 19 : 7742 56.
    • (1999) J Neurosci , vol.19 , pp. 7742-56
    • Selyanko, A.A.1    Hadley, J.K.2    Wood, I.C.3
  • 11
  • 12
    • 0141481906 scopus 로고    scopus 로고
    • Expression pattern of the ether-a-gogo-related (ERG) K+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system
    • Papa M, Boscia F, Canitano A et al. Expression pattern of the ether-a-gogo-related (ERG) K+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system. J Comp Neurol 2003 466 : 119 35.
    • (2003) J Comp Neurol , vol.466 , pp. 119-35
    • Papa, M.1    Boscia, F.2    Canitano, A.3
  • 13
    • 0035399872 scopus 로고    scopus 로고
    • Differential expression of genes encoding subthreshold-operating voltage-gated K+ channels in brain
    • Saganich MJ, Machado E, Rudy B. Differential expression of genes encoding subthreshold-operating voltage-gated K+ channels in brain. J Neurosci 2001 21 : 4609 24.
    • (2001) J Neurosci , vol.21 , pp. 4609-24
    • Saganich, M.J.1    MacHado, E.2    Rudy, B.3
  • 14
    • 0032542232 scopus 로고    scopus 로고
    • Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+ channels causes epilepsy
    • Schroeder BC, Kubisch C, Stein V, Jentsch TJ. Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+ channels causes epilepsy. Nature 1998 396 : 687 90.
    • (1998) Nature , vol.396 , pp. 687-90
    • Schroeder, B.C.1    Kubisch, C.2    Stein, V.3    Jentsch, T.J.4
  • 15
    • 0034712923 scopus 로고    scopus 로고
    • Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy
    • Cooper EC, Aldape KD, Abosch A et al. Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy. Proc Natl Acad Sci USA 2000 97 : 4914 9.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 4914-9
    • Cooper, E.C.1    Aldape, K.D.2    Abosch, A.3
  • 16
    • 24344487347 scopus 로고    scopus 로고
    • Expression pattern of the ether-a-go-go-related (ERG) family proteins in the adult mouse central nervous system: Evidence for coassembly of different subunits
    • Guasti L, Cilia E, Crociani O et al. Expression pattern of the ether-a-go-go-related (ERG) family proteins in the adult mouse central nervous system: evidence for coassembly of different subunits. J Comp Neurol 2005 491 : 157 74.
    • (2005) J Comp Neurol , vol.491 , pp. 157-74
    • Guasti, L.1    Cilia, E.2    Crociani, O.3
  • 17
    • 0031452869 scopus 로고    scopus 로고
    • Identification of two nervous system-specific members of the erg potassium channel gene family
    • Shi W, Wymore RS, Wang HS et al. Identification of two nervous system-specific members of the erg potassium channel gene family. J Neurosci 1997 17 : 9423 32.
    • (1997) J Neurosci , vol.17 , pp. 9423-32
    • Shi, W.1    Wymore, R.S.2    Wang, H.S.3
  • 18
    • 0031030414 scopus 로고    scopus 로고
    • The seizure locus encodes the Drosophila homolog of the HERG potassium channel
    • Wang XJ, Reynolds ER, Deak P, Hall LM. The seizure locus encodes the Drosophila homolog of the HERG potassium channel. J Neurosci 1997 17 : 882 90.
    • (1997) J Neurosci , vol.17 , pp. 882-90
    • Wang, X.J.1    Reynolds, E.R.2    Deak, P.3    Hall, L.M.4
  • 19
    • 0028292927 scopus 로고
    • A family of potassium channel genes related to EAG in Drosophila and mammals
    • Warmke JW, Ganetzky B. A family of potassium channel genes related to EAG in Drosophila and mammals. Proc Natl Acad Sci USA 1994 91 : 3438 42.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3438-42
    • Warmke, J.W.1    Ganetzky, B.2
  • 20
    • 0030670273 scopus 로고    scopus 로고
    • Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current
    • London B, Trudeau MC, Newton KP et al. Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current. Circ Res 1997 81 : 870 8.
    • (1997) Circ Res , vol.81 , pp. 870-8
    • London, B.1    Trudeau, M.C.2    Newton, K.P.3
  • 21
    • 0037462649 scopus 로고    scopus 로고
    • Cloning and functional characterization of the smooth muscle ether-a-go-go-related gene K+ channel. Potential role of a conserved amino acid substitution in the S4 region
    • Shoeb F, Malykhina AP, Akbarali HI. Cloning and functional characterization of the smooth muscle ether-a-go-go-related gene K+ channel. Potential role of a conserved amino acid substitution in the S4 region. J Biol Chem 2003 278 : 2503 14.
    • (2003) J Biol Chem , vol.278 , pp. 2503-14
    • Shoeb, F.1    Malykhina, A.P.2    Akbarali, H.I.3
  • 22
    • 0029002969 scopus 로고
    • A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel
    • Sanguinetti MC, Jiang C, Curran ME, Keating MT. A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell 1995 81 : 299 307.
    • (1995) Cell , vol.81 , pp. 299-307
    • Sanguinetti, M.C.1    Jiang, C.2    Curran, M.E.3    Keating, M.T.4
  • 24
    • 0030959835 scopus 로고    scopus 로고
    • Effects of a cognition-enhancer, linopirdine (DuP 996), on M-type potassium currents (IK(M)) and some other voltage- and ligand-gated membrane currents in rat sympathetic neurons
    • Lamas JA, Selyanko AA, Brown DA. Effects of a cognition-enhancer, linopirdine (DuP 996), on M-type potassium currents (IK(M)) and some other voltage- and ligand-gated membrane currents in rat sympathetic neurons. Eur J Neurosci 1997 9 : 605 16.
    • (1997) Eur J Neurosci , vol.9 , pp. 605-16
    • Lamas, J.A.1    Selyanko, A.A.2    Brown, D.A.3
  • 25
    • 0031809240 scopus 로고    scopus 로고
    • Two new potent neurotransmitter release enhancers, 10,10-bis(4- pyridinylmethyl)-9(10H)-anthracenone and 10,10-bis(2-fluoro-4-pyridinylmethyl)- 9(10H)-anthracenone: Comparison to linopirdine
    • Zaczek R, Chorvat RJ, Saye JA et al. Two new potent neurotransmitter release enhancers, 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone and 10,10-bis(2-fluoro-4-pyridinylmethyl)-9(10H)-anthracenone: comparison to linopirdine. J Pharmacol Exp Ther 1998 285 : 724 30.
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 724-30
    • Zaczek, R.1    Chorvat, R.J.2    Saye, J.A.3
  • 26
    • 0034642569 scopus 로고    scopus 로고
    • A constitutively open potassium channel formed by KCNQ1 and KCNE3
    • Schroeder BC, Waldegger S, Fehr S et al. A constitutively open potassium channel formed by KCNQ1 and KCNE3. Nature 2000 403 : 196 9.
    • (2000) Nature , vol.403 , pp. 196-9
    • Schroeder, B.C.1    Waldegger, S.2    Fehr, S.3
  • 27
    • 0033842282 scopus 로고    scopus 로고
    • Stereoselective interactions of the enantiomers of chromanol 293B with human voltage-gated potassium channels
    • Yang IC, Scherz MW, Bahinski A, Bennett PB, Murray KT. Stereoselective interactions of the enantiomers of chromanol 293B with human voltage-gated potassium channels. J Pharmacol Exp Ther 2000 294 : 955 62.
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 955-62
    • Yang, I.C.1    Scherz, M.W.2    Bahinski, A.3    Bennett, P.B.4    Murray, K.T.5
  • 28
    • 0035425653 scopus 로고    scopus 로고
    • Activation of expressed KCNQ potassium currents and native neuronal M-type potassium currents by the anti-convulsant drug retigabine
    • Tatulian L, Delmas P, Abogadie FC, Brown DA. Activation of expressed KCNQ potassium currents and native neuronal M-type potassium currents by the anti-convulsant drug retigabine. J Neurosci 2001 21 : 5535 45.
    • (2001) J Neurosci , vol.21 , pp. 5535-45
    • Tatulian, L.1    Delmas, P.2    Abogadie, F.C.3    Brown, D.A.4
  • 29
    • 0035141187 scopus 로고    scopus 로고
    • Apamin interacts with all subtypes of cloned small-conductance Ca2+-activated K+ channels
    • Grunnet M, Jensen BS, Olesen SP, Klaerke DA. Apamin interacts with all subtypes of cloned small-conductance Ca2+-activated K+ channels. Pflugers Arch 2001 441 : 544 50.
    • (2001) Pflugers Arch , vol.441 , pp. 544-50
    • Grunnet, M.1    Jensen, B.S.2    Olesen, S.P.3    Klaerke, D.A.4
  • 30
    • 0030610509 scopus 로고    scopus 로고
    • The role of the IsK protein in the specific pharmacological properties of the IKs channel complex
    • Busch AE, Busch GL, Ford E et al. The role of the IsK protein in the specific pharmacological properties of the IKs channel complex. Br J Pharmacol 1997 122 : 187 9.
    • (1997) Br J Pharmacol , vol.122 , pp. 187-9
    • Busch, A.E.1    Busch, G.L.2    Ford, E.3
  • 32
    • 0029088690 scopus 로고
    • Reduction of spike frequency adaptation and blockade of M-current in rat CA1 pyramidal neurones by linopirdine (DuP 996), a neurotransmitter release enhancer
    • Aiken SP, Lampe BJ, Murphy PA, Brown BS. Reduction of spike frequency adaptation and blockade of M-current in rat CA1 pyramidal neurones by linopirdine (DuP 996), a neurotransmitter release enhancer. Br J Pharmacol 1995 115 : 1163 8.
    • (1995) Br J Pharmacol , vol.115 , pp. 1163-8
    • Aiken, S.P.1    Lampe, B.J.2    Murphy, P.A.3    Brown, B.S.4
  • 33
    • 0031407385 scopus 로고    scopus 로고
    • Inhibition of M-current in cultured rat superior cervical ganglia by linopirdine: Mechanism of action studies
    • Costa AM, Brown BS. Inhibition of M-current in cultured rat superior cervical ganglia by linopirdine: mechanism of action studies. Neuropharmacology 1997 36 : 1747 53.
    • (1997) Neuropharmacology , vol.36 , pp. 1747-53
    • Costa, A.M.1    Brown, B.S.2
  • 35
    • 0043127363 scopus 로고    scopus 로고
    • KCNQ/M currents in sensory neurons: Significance for pain therapy
    • Passmore GM, Selyanko AA, Mistry M et al. KCNQ/M currents in sensory neurons: significance for pain therapy. J Neurosci 2003 23 : 7227 36.
    • (2003) J Neurosci , vol.23 , pp. 7227-36
    • Passmore, G.M.1    Selyanko, A.A.2    Mistry, M.3
  • 36
    • 25444462209 scopus 로고    scopus 로고
    • Expression and functional phenotype of mouse ERG K+ channels in the inner ear: Potential role in K+ regulation in the inner ear
    • Nie L, Gratton MA, Mu KJ, Dinglasan JN, Feng W, Yamoah EN. Expression and functional phenotype of mouse ERG K+ channels in the inner ear: potential role in K+ regulation in the inner ear. J Neurosci 2005 25 : 8671 9.
    • (2005) J Neurosci , vol.25 , pp. 8671-9
    • Nie, L.1    Gratton, M.A.2    Mu, K.J.3    Dinglasan, J.N.4    Feng, W.5    Yamoah, E.N.6
  • 37
    • 0031054075 scopus 로고    scopus 로고
    • A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome
    • Neyroud N, Tesson F, Denjoy I et al. A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome. Nat Genet 1997 15 : 186 9.
    • (1997) Nat Genet , vol.15 , pp. 186-9
    • Neyroud, N.1    Tesson, F.2    Denjoy, I.3
  • 40
    • 0034802582 scopus 로고    scopus 로고
    • Colocalization of KCNQ1/KCNE channel subunits in the mouse gastrointestinal tract
    • Dedek K, Waldegger S. Colocalization of KCNQ1/KCNE channel subunits in the mouse gastrointestinal tract. Pflugers Arch 2001 442 : 896 902.
    • (2001) Pflugers Arch , vol.442 , pp. 896-902
    • Dedek, K.1    Waldegger, S.2
  • 42
    • 0034802180 scopus 로고    scopus 로고
    • Xe991 reveals differences in K(+) channels regulating chloride secretion in murine airway and colonic epithelium
    • MacVinish LJ, Guo Y, Dixon AK, Murrell-Lagnado RD, Cuthbert AW. Xe991 reveals differences in K(+) channels regulating chloride secretion in murine airway and colonic epithelium. Mol Pharmacol 2001 60 : 753 60.
    • (2001) Mol Pharmacol , vol.60 , pp. 753-60
    • MacVinish, L.J.1    Guo, Y.2    Dixon, A.K.3    Murrell-Lagnado, R.D.4    Cuthbert, A.W.5
  • 43
    • 0036588377 scopus 로고    scopus 로고
    • An M-like outward current regulates the excitability of spinal motoneurones in the adult turtle
    • Alaburda A, Perrier JF, Hounsgaard J. An M-like outward current regulates the excitability of spinal motoneurones in the adult turtle. J Physiol 2002 540 : 875 81.
    • (2002) J Physiol , vol.540 , pp. 875-81
    • Alaburda, A.1    Perrier, J.F.2    Hounsgaard, J.3
  • 44
    • 0034161572 scopus 로고    scopus 로고
    • Reconstitution of muscarinic modulation of the KCNQ2/KCNQ3 K(+) channels that underlie the neuronal M current
    • Shapiro MS, Roche JP, Kaftan EJ, Cruzblanca H, Mackie K, Hille B. Reconstitution of muscarinic modulation of the KCNQ2/KCNQ3 K(+) channels that underlie the neuronal M current. J Neurosci 2000 20 : 1710 21.
    • (2000) J Neurosci , vol.20 , pp. 1710-21
    • Shapiro, M.S.1    Roche, J.P.2    Kaftan, E.J.3    Cruzblanca, H.4    MacKie, K.5    Hille, B.6
  • 45
    • 27144545381 scopus 로고    scopus 로고
    • Electrophysiological and functional effects of the KCNQ channel blocker XE991 on murine portal vein smooth muscle cells
    • Yeung SY, Greenwood IA. Electrophysiological and functional effects of the KCNQ channel blocker XE991 on murine portal vein smooth muscle cells. Br J Pharmacol 2005 146 : 585 95.
    • (2005) Br J Pharmacol , vol.146 , pp. 585-95
    • Yeung, S.Y.1    Greenwood, I.A.2


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