Integrin β3 regions controlling binding of murine mAb 7E3: Implications for the mechanism of integrin αIIbβ3 activation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 36, 2004, Pages 13114-13120

  Artoni, Andrea ^c   Li, JiHong ^c   Mitchell, Beau ^a   Ruan, Jian ^a   Takagi, Junichi ^b   Springer, Timothy A ^b   French, Deborah L ^a   Coller, Barry S ^a,c  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABCIXIMAB; ALPHA2BBETA3 INTEGRIN; BETA3 INTEGRIN; INTEGRIN; UNCLASSIFIED DRUG; DISULFIDE; EPITOPE; FIBRINOGEN RECEPTOR; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; PEPTIDE FRAGMENT;

ALLOSTERISM; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BINDING SITE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROL SYSTEM; CONTROLLED STUDY; CRYSTAL STRUCTURE; FLOW CYTOMETRY; HEART PROTECTION; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR MODEL; NONHUMAN; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN STRUCTURE; RECEPTOR OCCUPANCY; STRUCTURE ANALYSIS; THROMBOCYTE ACTIVATION; ANIMAL; CHEMISTRY; METABOLISM; MOUSE; PROTEIN CONFORMATION; SPECIES DIFFERENCE;

ANIMALIA; MURINAE;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, MONOCLONAL; DISULFIDES; EPITOPES; HUMANS; IMMUNOGLOBULIN G; INTEGRIN BETA3; MICE; PEPTIDE FRAGMENTS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN CONFORMATION; SPECIES SPECIFICITY;

EID: 4444324533     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0404201101     Document Type: Article

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