메뉴 건너뛰기




Volumn 47, Issue 6, 2006, Pages 352-360

Thiazolidinediones: Antidiabetic drugs with cardiovascular effects

Author keywords

Atherosclerosis; Diabetes mellitus; Endothelial function; Insulin resistance

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; METFORMIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PIOGLITAZONE; PLACEBO; ROSIGLITAZONE; SIMVASTATIN; SULFONYLUREA; ANTIDIABETIC AGENT;

EID: 34247176346     PISSN: 10117970     EISSN: 10117970     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (7)

References (93)
  • 1
    • 0031752685 scopus 로고    scopus 로고
    • Global burden of diabetes, 1995-2025: Prevalence, numerical estimates, and projections
    • King H, Aubert RE, Herman WH: Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care 1998; 21: 1414-1431.
    • (1998) Diabetes Care , vol.21 , pp. 1414-1431
    • King, H.1    Aubert, R.E.2    Herman, W.H.3
  • 2
    • 0029739373 scopus 로고    scopus 로고
    • Cardiovascular mortality and morbidity in type-2 diabetes mellitus
    • Schernthaner G: Cardiovascular mortality and morbidity in type-2 diabetes mellitus. Diabetes Res Clin Pract 1996; 31 (Suppl): S3-13.
    • (1996) Diabetes Res Clin Pract , vol.31 , Issue.SUPPL.
    • Schernthaner, G.1
  • 3
    • 0032560807 scopus 로고    scopus 로고
    • Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction
    • Haffner SM, Lehto S, Rönnemaa T, et al: Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med 1998; 339: 229-234.
    • (1998) N Engl J Med , vol.339 , pp. 229-234
    • Haffner, S.M.1    Lehto, S.2    Rönnemaa, T.3
  • 4
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferators activated receptor gamma (PPAR gamma)
    • Lehmann JM, Moore LB, Smith-Oliver TA, et al: An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferators activated receptor gamma (PPAR gamma). J Biol Chem 1995; 270: 12953-12956.
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3
  • 5
    • 4243364498 scopus 로고    scopus 로고
    • Durability of glycemic control with pioglitazone in long-term combination and monotherapy
    • Einhorn D, Kipnes M, Glazer NB, et al: Durability of glycemic control with pioglitazone in long-term combination and monotherapy. Diabetes 2001; 50 (Suppl): A111.
    • (2001) Diabetes , vol.50 , Issue.SUPPL.
    • Einhorn, D.1    Kipnes, M.2    Glazer, N.B.3
  • 8
    • 85069094515 scopus 로고    scopus 로고
    • ACTOS® pioglitazone hydrochloride, Prescribing information, Takeda Pharmaceuticals America, Inc
    • ACTOS® (pioglitazone hydrochloride): Prescribing information, Takeda Pharmaceuticals America, Inc.
  • 9
    • 0034930107 scopus 로고    scopus 로고
    • Thiazolidinediones and liver toxicity
    • Scheen AJ: Thiazolidinediones and liver toxicity. Diabetes Metab 2001; 27: 305-313.
    • (2001) Diabetes Metab , vol.27 , pp. 305-313
    • Scheen, A.J.1
  • 10
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Nuclear control of metabolism
    • Desvergne B, Wahli W: Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 1999; 20: 649-688.
    • (1999) Endocr Rev , vol.20 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 11
    • 0036183630 scopus 로고    scopus 로고
    • The mechanisms of action of PPARs
    • Berger J, Moller DE: The mechanisms of action of PPARs. Annu Rev Med 2002; 53: 409-435.
    • (2002) Annu Rev Med , vol.53 , pp. 409-435
    • Berger, J.1    Moller, D.E.2
  • 12
    • 0035976638 scopus 로고    scopus 로고
    • Nuclear receptors and lipid physiology: Opening the X-files
    • Chawla A, Repa JJ, Evans RM, et al: Nuclear receptors and lipid physiology: opening the X-files. Science 2001; 294: 1866-1870.
    • (2001) Science , vol.294 , pp. 1866-1870
    • Chawla, A.1    Repa, J.J.2    Evans, R.M.3
  • 13
    • 0033793133 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs): Nuclear receptors at the crossroads between lipid metabolism and inflammation
    • Chinetti G, Fruchart JC, Staels B: Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation. Inflamm Res 2000; 49: 497-505.
    • (2000) Inflamm Res , vol.49 , pp. 497-505
    • Chinetti, G.1    Fruchart, J.C.2    Staels, B.3
  • 14
    • 0033527030 scopus 로고    scopus 로고
    • Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol
    • Rubins HB, Robins SJ, Collins D, et al: Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. N Engl J Med 1999; 341: 410-418.
    • (1999) N Engl J Med , vol.341 , pp. 410-418
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3
  • 15
    • 10044224688 scopus 로고    scopus 로고
    • Roles of peroxisome proliferator-activated receptor delta (PPARdelta) in the control of fatty acid catabolism. A new target for the treatment of metabolic syndrome
    • Luquet S, Lopez-Soriano J, Holst D, et al: Roles of peroxisome proliferator-activated receptor delta (PPARdelta) in the control of fatty acid catabolism. A new target for the treatment of metabolic syndrome. Biochimie 2004; 86: 833-837.
    • (2004) Biochimie , vol.86 , pp. 833-837
    • Luquet, S.1    Lopez-Soriano, J.2    Holst, D.3
  • 16
    • 2442711384 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and atherogenesis: Regulators of gene expression in vascular cells
    • Marx N, Duez H, Fruchart JC, et al: Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells. Circ Res 2004; 94: 1168-1178.
    • (2004) Circ Res , vol.94 , pp. 1168-1178
    • Marx, N.1    Duez, H.2    Fruchart, J.C.3
  • 17
    • 0034923501 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma and metabolic disease
    • Willson TM, Lambert MH, Kliewer SA: Peroxisome proliferator-activated receptor gamma and metabolic disease. Annu Rev Biochem 2001; 70: 341-367.
    • (2001) Annu Rev Biochem , vol.70 , pp. 341-367
    • Willson, T.M.1    Lambert, M.H.2    Kliewer, S.A.3
  • 18
    • 0029149884 scopus 로고
    • Clinical implications of insulin resistance syndromes
    • Davidson MB: Clinical implications of insulin resistance syndromes. Am J Med 1995; 99: 420-426.
    • (1995) Am J Med , vol.99 , pp. 420-426
    • Davidson, M.B.1
  • 19
    • 0035897696 scopus 로고    scopus 로고
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Executive Summary of the Third Report of the National Cholesterol Education Program NCEP
    • Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001; 285: 2486-2497.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 20
    • 0035671770 scopus 로고    scopus 로고
    • Effect of rosiglitazone on glucose and nonesterified fatty acid metabolism in Type 2 diabetic patients
    • Miyazaki Y, Glass L, Triplitt C, et al: Effect of rosiglitazone on glucose and nonesterified fatty acid metabolism in Type 2 diabetic patients. Diabetologia 2001; 44: 2210-2219.
    • (2001) Diabetologia , vol.44 , pp. 2210-2219
    • Miyazaki, Y.1    Glass, L.2    Triplitt, C.3
  • 21
    • 0036068327 scopus 로고    scopus 로고
    • Troglitazone but not metformin restores insulin stimulated phosphoinositide 3-kinase activity and increases p110[β] protein levels in skeletal muscle of type 2 diabetic subjects
    • Kim YB, Ciaraldi TP, Kong A, et al: Troglitazone but not metformin restores insulin stimulated phosphoinositide 3-kinase activity and increases p110[β] protein levels in skeletal muscle of type 2 diabetic subjects. Diabetes 2002; 51: 443-448.
    • (2002) Diabetes , vol.51 , pp. 443-448
    • Kim, Y.B.1    Ciaraldi, T.P.2    Kong, A.3
  • 22
    • 0036072223 scopus 로고    scopus 로고
    • Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients
    • Miyazaki Y, Mahankali A, Matsuda M, et al: Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients. J Clin Endocrinol Metab 2002; 87: 2784-2791.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2784-2791
    • Miyazaki, Y.1    Mahankali, A.2    Matsuda, M.3
  • 23
    • 0041883085 scopus 로고    scopus 로고
    • Influence of rosiglitazone treatment on β-cell function in type 2 diabetes: Evidence of an increased ability of glucose to entrain high-frequency insulin pulsatility
    • Juhl CB, Hollingdal M, P_rksen N, et al: Influence of rosiglitazone treatment on β-cell function in type 2 diabetes: evidence of an increased ability of glucose to entrain high-frequency insulin pulsatility. J Clin Endocrinol Metab 2003; 88: 3794-3800.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 3794-3800
    • Juhl, C.B.1    Hollingdal, M.2    Porksen, N.3
  • 24
    • 19244365650 scopus 로고    scopus 로고
    • Thiazolidinediones
    • Yki-Järvinen H: Thiazolidinediones. N Engl J Med 2004; 351: 1106-1118.
    • (2004) N Engl J Med , vol.351 , pp. 1106-1118
    • Yki-Järvinen, H.1
  • 25
    • 17544396164 scopus 로고    scopus 로고
    • Activators of peroxisome proliferator-activated receptor have depot-specific effects on human preadipocyte differentiation
    • Adams M, Montague CT, Prins JB, et al: Activators of peroxisome proliferator-activated receptor have depot-specific effects on human preadipocyte differentiation. J Clin Invest. 1997; 100: 3149-3153.
    • (1997) J Clin Invest , vol.100 , pp. 3149-3153
    • Adams, M.1    Montague, C.T.2    Prins, J.B.3
  • 26
    • 0033578476 scopus 로고    scopus 로고
    • Pharmacologic therapy for type 2 diabetes mellitus
    • DeFronzo R: Pharmacologic therapy for type 2 diabetes mellitus. Ann Intern Med 1999; 131: 281-303.
    • (1999) Ann Intern Med , vol.131 , pp. 281-303
    • DeFronzo, R.1
  • 27
    • 0036551421 scopus 로고    scopus 로고
    • Khan MA, St: Peter JV, Xue JL: A prospective, randomized comparison of the metabolic effects of pioglitazone or rosiglitazone in patients with type 2 diabetes who were previously treated with troglitazone. Diabetes Care 2002; 25: 708-711.
    • Khan MA, St: Peter JV, Xue JL: A prospective, randomized comparison of the metabolic effects of pioglitazone or rosiglitazone in patients with type 2 diabetes who were previously treated with troglitazone. Diabetes Care 2002; 25: 708-711.
  • 28
    • 0000396919 scopus 로고    scopus 로고
    • Rosiglitazone favourably affects LDL-C and HDL-C heterogeneity in type 2 diabetes [abstract]
    • Brunzell J, Cohen BR, Kreider M: Rosiglitazone favourably affects LDL-C and HDL-C heterogeneity in type 2 diabetes [abstract]. Diabetes 2001; 50(Suppl 2): A141.
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 2
    • Brunzell, J.1    Cohen, B.R.2    Kreider, M.3
  • 29
    • 0001214310 scopus 로고    scopus 로고
    • Pioglitazone reduces dense LDL-particles in patients with type-2 diabetes
    • abstract
    • Winkler K, Friedrich I, Nauck M, Wieland H, Maerz W: Pioglitazone reduces dense LDL-particles in patients with type-2 diabetes. Diabetes 2001; 50(Suppl 2): A147 (abstract).
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 2
    • Winkler, K.1    Friedrich, I.2    Nauck, M.3    Wieland, H.4    Maerz, W.5
  • 30
    • 0027502421 scopus 로고
    • Susceptibility of small, dense, low-density lipoproteins to oxidative modification in subjects with the atherogenic lipoprotein phenotype, pattern B
    • Chait A, Brazg RL, Tribble DL, et al: Susceptibility of small, dense, low-density lipoproteins to oxidative modification in subjects with the atherogenic lipoprotein phenotype, pattern B Am J Med 1993; 94: 350-356.
    • (1993) Am J Med , vol.94 , pp. 350-356
    • Chait, A.1    Brazg, R.L.2    Tribble, D.L.3
  • 31
    • 0346122777 scopus 로고    scopus 로고
    • Pioglitazone inhibits LOX-1 expression in human coronary artery endothelial cells by reducing intracellular superoxide radical generation
    • Mehta JL, Hu B, Chen J, et al: Pioglitazone inhibits LOX-1 expression in human coronary artery endothelial cells by reducing intracellular superoxide radical generation. Arterioscler Thromb Vasc Biol 2003; 23: 2203-2208.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 2203-2208
    • Mehta, J.L.1    Hu, B.2    Chen, J.3
  • 32
    • 1842555259 scopus 로고    scopus 로고
    • Simvastatin/Thiazolidinedione Study Group: Effects of simvastatin on the lipid profile and attainment of low-density lipoprotein cholesterol goals when added to thiazolidinedione therapy in patients with type 2 diabetes mellitus: a multicenter, randomized, double-blind, placebo-controlled trial
    • Lewin AJ, Kipnes MS, Meneghini LF, et al: Simvastatin/Thiazolidinedione Study Group: Effects of simvastatin on the lipid profile and attainment of low-density lipoprotein cholesterol goals when added to thiazolidinedione therapy in patients with type 2 diabetes mellitus: a multicenter, randomized, double-blind, placebo-controlled trial. Clin Ther 2004; 26: 379-389.
    • (2004) Clin Ther , vol.26 , pp. 379-389
    • Lewin, A.J.1    Kipnes, M.S.2    Meneghini, L.F.3
  • 34
    • 0032779907 scopus 로고    scopus 로고
    • Metabolic and vascular effects of the thiazolidinedione troglitazone
    • Saleh YM, Mudaliar SR, Henry RR: Metabolic and vascular effects of the thiazolidinedione troglitazone. Diabetes Rev 7: 55-76, 1999.
    • (1999) Diabetes Rev , vol.7 , pp. 55-76
    • Saleh, Y.M.1    Mudaliar, S.R.2    Henry, R.R.3
  • 35
    • 0028911412 scopus 로고
    • Prospective study of lipoprotein(a) as a risk factor for atherosclerotic cardiovascular disease in patients with diabetes
    • Hiraga T, Kobayashi T, Okubo M, et al: Prospective study of lipoprotein(a) as a risk factor for atherosclerotic cardiovascular disease in patients with diabetes. Diabetes Care 1995; 18: 241-244.
    • (1995) Diabetes Care , vol.18 , pp. 241-244
    • Hiraga, T.1    Kobayashi, T.2    Okubo, M.3
  • 37
    • 0035141015 scopus 로고    scopus 로고
    • Does pioglitazone, like troglitazone, increase serum levels of lipoprotein(a) in diabetic patients?
    • Nagai Y, Abe T, Nomura G: Does pioglitazone, like troglitazone, increase serum levels of lipoprotein(a) in diabetic patients? Diabetes Care 2001; 24: 408-409.
    • (2001) Diabetes Care , vol.24 , pp. 408-409
    • Nagai, Y.1    Abe, T.2    Nomura, G.3
  • 38
    • 0032930211 scopus 로고    scopus 로고
    • Troglitazone's effect on lipoprotein(a) levels
    • Ovalle F, Bell DS: Troglitazone's effect on lipoprotein(a) levels. Diabetes Care 1999; 22: 859-860.
    • (1999) Diabetes Care , vol.22 , pp. 859-860
    • Ovalle, F.1    Bell, D.S.2
  • 39
    • 0038142254 scopus 로고    scopus 로고
    • The effect of rosiglitazone on serum lipoprotein(a) levels in Korean patients with type 2 diabetes mellitus
    • Ko SH, Song KH, Ahn YB, et al: The effect of rosiglitazone on serum lipoprotein(a) levels in Korean patients with type 2 diabetes mellitus. Metabolism 2003; 52: 731-734.
    • (2003) Metabolism , vol.52 , pp. 731-734
    • Ko, S.H.1    Song, K.H.2    Ahn, Y.B.3
  • 40
    • 23944516265 scopus 로고    scopus 로고
    • The effect of rosiglitazone on novel atherosclerotic risk factors in patients with type 2 diabetes mellitus and hypertension. An open-label observational study
    • Sarafidis PA, Lasaridis AN, Nilsson PM, et al: The effect of rosiglitazone on novel atherosclerotic risk factors in patients with type 2 diabetes mellitus and hypertension. An open-label observational study. Metabolism 2005; 54: 1236-1242.
    • (2005) Metabolism , vol.54 , pp. 1236-1242
    • Sarafidis, P.A.1    Lasaridis, A.N.2    Nilsson, P.M.3
  • 41
    • 0029142479 scopus 로고
    • Blood pressure lowering by pioglitazone: Evidence for a direct vascular effect
    • Buchanan TA, Meehan WP, Jeng YY, et al: Blood pressure lowering by pioglitazone: Evidence for a direct vascular effect. J Clin Invest 1995; 96: 354-360.
    • (1995) J Clin Invest , vol.96 , pp. 354-360
    • Buchanan, T.A.1    Meehan, W.P.2    Jeng, Y.Y.3
  • 42
    • 0031768586 scopus 로고    scopus 로고
    • Effect of troglitazone on microalbuminuria in patients with incipient diabetic nephropathy
    • Imano E, Kanda T, Nakatani Y, et al: Effect of troglitazone on microalbuminuria in patients with incipient diabetic nephropathy. Diabetes Care 1998; 21: 2135-2139.
    • (1998) Diabetes Care , vol.21 , pp. 2135-2139
    • Imano, E.1    Kanda, T.2    Nakatani, Y.3
  • 43
    • 0024203205 scopus 로고
    • Hypertension in diabetes mellitus
    • Rosenstock J, Raskin P: Hypertension in diabetes mellitus. Cardiol Clin 1988; 6: 547-560.
    • (1988) Cardiol Clin , vol.6 , pp. 547-560
    • Rosenstock, J.1    Raskin, P.2
  • 44
    • 0037076294 scopus 로고    scopus 로고
    • Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: Role of peroxisome proliferator-activated receptor-gamma
    • Diep QN, El Mabrouk M, Cohn JS, et al: Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: role of peroxisome proliferator-activated receptor-gamma. Circulation 2002; 105: 2296-2302.
    • (2002) Circulation , vol.105 , pp. 2296-2302
    • Diep, Q.N.1    El Mabrouk, M.2    Cohn, J.S.3
  • 45
    • 0029555474 scopus 로고
    • Pioglitazone attenuates diet induced hypertension in rats
    • Kaufman LN, Peterson MM, DeGrange LM: Pioglitazone attenuates diet induced hypertension in rats. Metabolism 1995; 44: 1105-1109.
    • (1995) Metabolism , vol.44 , pp. 1105-1109
    • Kaufman, L.N.1    Peterson, M.M.2    DeGrange, L.M.3
  • 46
    • 0032401699 scopus 로고    scopus 로고
    • Mechanisms of vasorelaxation induced by troglitazone, a novel antidiabetic drug, in the porcine coronary artery
    • Kawasaki J, Hirano K, Nishimura J, et al: Mechanisms of vasorelaxation induced by troglitazone, a novel antidiabetic drug, in the porcine coronary artery. Circulation 1998; 98: 2446-2452.
    • (1998) Circulation , vol.98 , pp. 2446-2452
    • Kawasaki, J.1    Hirano, K.2    Nishimura, J.3
  • 47
    • 0030989050 scopus 로고    scopus 로고
    • Troglitazone reduces contraction by inhibition of vascular smooth muscle cell Ca+2 currents and not endothelial nitric oxide production
    • Song J, Walsh MF, Igwe R, et al: Troglitazone reduces contraction by inhibition of vascular smooth muscle cell Ca+2 currents and not endothelial nitric oxide production. Diabetes 1997; 46: 659-664.
    • (1997) Diabetes , vol.46 , pp. 659-664
    • Song, J.1    Walsh, M.F.2    Igwe, R.3
  • 48
    • 4344606883 scopus 로고    scopus 로고
    • Ambulatory blood pressure reduction after rosiglitazone treatment in patients with type 2 diabetes and hypertension correlates with insulin sensitivity increase
    • Sarafidis PA, Lasaridis AN, Nilsson PM, et al: Ambulatory blood pressure reduction after rosiglitazone treatment in patients with type 2 diabetes and hypertension correlates with insulin sensitivity increase. J Hypertens 2004; 22: 1673-1674.
    • (2004) J Hypertens , vol.22 , pp. 1673-1674
    • Sarafidis, P.A.1    Lasaridis, A.N.2    Nilsson, P.M.3
  • 49
    • 0026643310 scopus 로고
    • Prospective study of microalbuminuria as a predictor of mortality in NIDDM
    • Mattock MB, Morrish NJ, Viberti GC, et al: Prospective study of microalbuminuria as a predictor of mortality in NIDDM Diabetes 1992; 41: 736-741.
    • (1992) Diabetes , vol.41 , pp. 736-741
    • Mattock, M.B.1    Morrish, N.J.2    Viberti, G.C.3
  • 50
    • 30444448702 scopus 로고    scopus 로고
    • Microalbuminuria as a marker of cardiovascular risk in patients with type 2 diabetes
    • Erdmann E: Microalbuminuria as a marker of cardiovascular risk in patients with type 2 diabetes. Int J Cardiol 2006; 107: 147-153.
    • (2006) Int J Cardiol , vol.107 , pp. 147-153
    • Erdmann, E.1
  • 51
    • 21344466513 scopus 로고    scopus 로고
    • Rosiglitazone improves glomerular hyperfiltration, renal endothelial dysfunction, and microalbuminuria of incipient diabetic nephropathy in patients
    • Pistrosch F, Herbrig K, Kindel B, et al: Rosiglitazone improves glomerular hyperfiltration, renal endothelial dysfunction, and microalbuminuria of incipient diabetic nephropathy in patients. Diabetes 2005; 54: 2206-2211.
    • (2005) Diabetes , vol.54 , pp. 2206-2211
    • Pistrosch, F.1    Herbrig, K.2    Kindel, B.3
  • 52
    • 0032890834 scopus 로고    scopus 로고
    • PPAR-gamma ligands inhibit migration mediated by multiple chemoattractants in vascular smooth muscle cells
    • Goetze S, Xi XP, Kawano H, et al: PPAR-gamma ligands inhibit migration mediated by multiple chemoattractants in vascular smooth muscle cells. J Cardiovasc Pharmacol 1999; 33: 798-806.
    • (1999) J Cardiovasc Pharmacol , vol.33 , pp. 798-806
    • Goetze, S.1    Xi, X.P.2    Kawano, H.3
  • 53
    • 0034711678 scopus 로고    scopus 로고
    • Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators
    • Pasceri V, Wu HD, Willerson JT, et al: Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators. Circulation 2000; 101: 235-238.
    • (2000) Circulation , vol.101 , pp. 235-238
    • Pasceri, V.1    Wu, H.D.2    Willerson, J.T.3
  • 54
    • 0037231474 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma ligands increase release of nitric oxide from endothelial cells
    • Calnek DS, Mazzella L, Roser S, et al: Peroxisome proliferator-activated receptor-gamma ligands increase release of nitric oxide from endothelial cells. Arterioscler Thromb Vasc Biol 2003; 23: 52-57.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 52-57
    • Calnek, D.S.1    Mazzella, L.2    Roser, S.3
  • 55
    • 0033520304 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway
    • Delerive P, Martin-Nizard F, Chinetti G, et al: Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway. Circ Res 2003; 85: 394-402.
    • (2003) Circ Res , vol.85 , pp. 394-402
    • Delerive, P.1    Martin-Nizard, F.2    Chinetti, G.3
  • 56
    • 0344333464 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells
    • Marx N, Schönbeck U, Lazar MA, et al: Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells. Circ Res 1998; 83: 1097-1103.
    • (1998) Circ Res , vol.83 , pp. 1097-1103
    • Marx, N.1    Schönbeck, U.2    Lazar, M.A.3
  • 57
    • 28044456326 scopus 로고    scopus 로고
    • Impact of thiazolidinedione therapy on atherogenesis
    • van Wijk JPH, Rabelink TJ: Impact of thiazolidinedione therapy on atherogenesis. Curr Atheroscler Rep 2005; 7: 369-374.
    • (2005) Curr Atheroscler Rep , vol.7 , pp. 369-374
    • van Wijk, J.P.H.1    Rabelink, T.J.2
  • 58
    • 0032145662 scopus 로고    scopus 로고
    • Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes
    • Kai H, Ikeda H, Yasukawa H, et al: Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes. J Am Coll Cardiol 1998; 32: 368-372.
    • (1998) J Am Coll Cardiol , vol.32 , pp. 368-372
    • Kai, H.1    Ikeda, H.2    Yasukawa, H.3
  • 59
    • 0035707186 scopus 로고    scopus 로고
    • Evidence of increased matrix metalloproteinase-9 concentration in patients following cardiopulmonary bypass
    • Steinberg J, Fink G, Picone A, et al: Evidence of increased matrix metalloproteinase-9 concentration in patients following cardiopulmonary bypass. J Extra Corpor Technol 2001; 33: 218-222.
    • (2001) J Extra Corpor Technol , vol.33 , pp. 218-222
    • Steinberg, J.1    Fink, G.2    Picone, A.3
  • 60
    • 0031465692 scopus 로고    scopus 로고
    • Arterial thrombosis and atherosclerosis in diabetes
    • Jokl R, Colwell JA: Arterial thrombosis and atherosclerosis in diabetes. Diabetes Reviews 1997; 5: 316.
    • (1997) Diabetes Reviews , vol.5 , pp. 316
    • Jokl, R.1    Colwell, J.A.2
  • 61
    • 0033368080 scopus 로고    scopus 로고
    • Coronary artery disease and fibrinolysis: From the blood to the vessel wall
    • Sobel BE: Coronary artery disease and fibrinolysis: from the blood to the vessel wall. Thromb Haemost 1999; 82(Suppl 1): 8-13.
    • (1999) Thromb Haemost , vol.82 , Issue.SUPPL. 1 , pp. 8-13
    • Sobel, B.E.1
  • 62
    • 0034456123 scopus 로고    scopus 로고
    • Differential regulation by troglitazone of plasminogen activator inhibitor type 1 in human hepatic and vascular cells
    • Nordt TK, Peter K, Bode C, et al: Differential regulation by troglitazone of plasminogen activator inhibitor type 1 in human hepatic and vascular cells. J Clin Endocrinol Metab 2000; 85: 1563-1568.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1563-1568
    • Nordt, T.K.1    Peter, K.2    Bode, C.3
  • 63
    • 0035528852 scopus 로고    scopus 로고
    • PPAR γ and atherosclerosis. Effects on cell growth and movement
    • Hsueh WA, Law RE: PPAR γ and atherosclerosis. Effects on cell growth and movement. Arterioscler Thromb Vasc Biol 2001; 21: 1891-1895.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1891-1895
    • Hsueh, W.A.1    Law, R.E.2
  • 64
    • 0037031267 scopus 로고    scopus 로고
    • Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus
    • Haffner SM, Greenberg AS, Weston WM, et al: Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus. Circulation 2002; 106: 679-684.
    • (2002) Circulation , vol.106 , pp. 679-684
    • Haffner, S.M.1    Greenberg, A.S.2    Weston, W.M.3
  • 65
    • 0037324289 scopus 로고    scopus 로고
    • Antidiabetic PPAR γ -activator rosiglitazone reduces MMP-9 serum levels in type-2 diabetic patients with coronary artery disease
    • Marx N, Froehlich J, Siam L, et al: Antidiabetic PPAR γ -activator rosiglitazone reduces MMP-9 serum levels in type-2 diabetic patients with coronary artery disease. Arterioscler Thromb Vasc Biol 2003; 23: 283-288.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 283-288
    • Marx, N.1    Froehlich, J.2    Siam, L.3
  • 66
    • 0034098771 scopus 로고    scopus 로고
    • Rosiglitazone short-term monotherapy lowers fasting and post-prandial glucose in patients with type II diabetes
    • Raskin P, Rappaport EB, Cole ST, et al: Rosiglitazone short-term monotherapy lowers fasting and post-prandial glucose in patients with type II diabetes. Diabetologia 2000; 43: 278-284.
    • (2000) Diabetologia , vol.43 , pp. 278-284
    • Raskin, P.1    Rappaport, E.B.2    Cole, S.T.3
  • 67
    • 0037461106 scopus 로고    scopus 로고
    • Effect of rosiglitazone treatment on soluble CD40L in type-2 diabetic patients with coronary artery disease
    • Marx N, Imhof A, Froehlich J, et al: Effect of rosiglitazone treatment on soluble CD40L in type-2 diabetic patients with coronary artery disease. Circulation 2003; 107: 1954-1957.
    • (2003) Circulation , vol.107 , pp. 1954-1957
    • Marx, N.1    Imhof, A.2    Froehlich, J.3
  • 68
    • 0842289940 scopus 로고    scopus 로고
    • In type 2 diabetes, rosiglitazone therapy for insulin resistance ameliorates endothelial dysfunction independent of glucose control
    • Pistrosch F, Passauer J, Fischer S, et al: In type 2 diabetes, rosiglitazone therapy for insulin resistance ameliorates endothelial dysfunction independent of glucose control. Diabetes Care 2004; 27: 484-490.
    • (2004) Diabetes Care , vol.27 , pp. 484-490
    • Pistrosch, F.1    Passauer, J.2    Fischer, S.3
  • 69
    • 3142608994 scopus 로고    scopus 로고
    • Effects of rosiglitazone on endothelial function in men with coronary artery disease without diabetes mellitus
    • Sidhu JS, Cowan D, Kaski JC: Effects of rosiglitazone on endothelial function in men with coronary artery disease without diabetes mellitus. Am J Cardiol 2004; 94: 151-156.
    • (2004) Am J Cardiol , vol.94 , pp. 151-156
    • Sidhu, J.S.1    Cowan, D.2    Kaski, J.C.3
  • 70
    • 0842303207 scopus 로고    scopus 로고
    • Effects of rosiglitazone on endothelial function, C-reactive protein, and components of the metabolic syndrome in nondiabetic patients with the metabolic syndrome
    • Wang TD, Chen WJ, Lin JW, et al: Effects of rosiglitazone on endothelial function, C-reactive protein, and components of the metabolic syndrome in nondiabetic patients with the metabolic syndrome. Am J Cardiol 2004; 93: 362-365.
    • (2004) Am J Cardiol , vol.93 , pp. 362-365
    • Wang, T.D.1    Chen, W.J.2    Lin, J.W.3
  • 71
    • 10744225126 scopus 로고    scopus 로고
    • Antiatherogenic effect of pioglitazone in type 2 diabetic patients irrespective of the responsiveness to its antidiabetic effect
    • Satoh N, Ogawa Y, Usui T, et al: Antiatherogenic effect of pioglitazone in type 2 diabetic patients irrespective of the responsiveness to its antidiabetic effect. Diabetes Care 2003; 26: 2493-2499.
    • (2003) Diabetes Care , vol.26 , pp. 2493-2499
    • Satoh, N.1    Ogawa, Y.2    Usui, T.3
  • 72
    • 0030826182 scopus 로고    scopus 로고
    • Common carotid intima-media thickness and risk of stroke and myocardial infarction: The Rotterdam Study
    • Bots ML, Hoes AW, Koudstaal PJ, et al: Common carotid intima-media thickness and risk of stroke and myocardial infarction: The Rotterdam Study. Circulation 1997; 96: 1432-1437.
    • (1997) Circulation , vol.96 , pp. 1432-1437
    • Bots, M.L.1    Hoes, A.W.2    Koudstaal, P.J.3
  • 73
    • 2442626743 scopus 로고    scopus 로고
    • Effect of rosiglitazone on common carotid intima-media thickness progression in coronary artery disease patients without diabetes mellitus
    • Sidhu JS, Kaposzta Z, Markus HS, et al: Effect of rosiglitazone on common carotid intima-media thickness progression in coronary artery disease patients without diabetes mellitus. Arterioscler Thromb Vasc Biol 2004; 24: 930-934.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 930-934
    • Sidhu, J.S.1    Kaposzta, Z.2    Markus, H.S.3
  • 74
    • 0034920087 scopus 로고    scopus 로고
    • Rapid communication: Inhibitory effect of pioglitazone on carotid arterial wall thickness in type 2 diabetes
    • Koshiyama H, Shimono D, Kuwamura N, et al: Rapid communication: inhibitory effect of pioglitazone on carotid arterial wall thickness in type 2 diabetes. J Clin Endo Metab 2001; 86: 3452-3456.
    • (2001) J Clin Endo Metab , vol.86 , pp. 3452-3456
    • Koshiyama, H.1    Shimono, D.2    Kuwamura, N.3
  • 75
    • 0342424770 scopus 로고    scopus 로고
    • Influence of treatment modality on angiographic outcome after coronary stenting in diabetic patients: A controlled study
    • Schofer J, Schluter M, Rau T, et al: Influence of treatment modality on angiographic outcome after coronary stenting in diabetic patients: a controlled study. J Am Coll Cardiol 2000; 35: 1554-1559.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 1554-1559
    • Schofer, J.1    Schluter, M.2    Rau, T.3
  • 76
    • 27844538450 scopus 로고    scopus 로고
    • Pioglitazone reduces neointima volume after coronary stent implantation: A randomized, placebo-controlled, double-blind trial in nondiabetic patients
    • Marx N, Wohrle J, Nusser T, et al: Pioglitazone reduces neointima volume after coronary stent implantation: a randomized, placebo-controlled, double-blind trial in nondiabetic patients. Circulation 2005; 112: 2792-2798.
    • (2005) Circulation , vol.112 , pp. 2792-2798
    • Marx, N.1    Wohrle, J.2    Nusser, T.3
  • 77
    • 19444368068 scopus 로고    scopus 로고
    • Thiazolidinedione treatment attenuates diffuse neointimal hyperplasia in restenotic lesions after coronary stent implantation in type 2 diabetic patients: An intravascular ultrasound study
    • Takagi T, Yamamuro A, Tamita K, et al: Thiazolidinedione treatment attenuates diffuse neointimal hyperplasia in restenotic lesions after coronary stent implantation in type 2 diabetic patients: an intravascular ultrasound study. J Cardiol 2005; 45: 139-147.
    • (2005) J Cardiol , vol.45 , pp. 139-147
    • Takagi, T.1    Yamamuro, A.2    Tamita, K.3
  • 78
    • 7444231513 scopus 로고    scopus 로고
    • Preventative effects of rosiglitazone on restenosis after coronary stent implantation in patients with type 2 diabetes
    • Choi D, Kim SK, Choi SH, et al: Preventative effects of rosiglitazone on restenosis after coronary stent implantation in patients with type 2 diabetes. Diabetes Care 2004; 27: 2654-2660.
    • (2004) Diabetes Care , vol.27 , pp. 2654-2660
    • Choi, D.1    Kim, S.K.2    Choi, S.H.3
  • 79
    • 3042856805 scopus 로고    scopus 로고
    • Effect of rosiglitazone on restenosis after coronary stenting in patients with type 2 diabetes
    • Osman A, Otero J, Brizolara A, et al: Effect of rosiglitazone on restenosis after coronary stenting in patients with type 2 diabetes. Am Heart J 2004; 147: E23.
    • (2004) Am Heart J , vol.147
    • Osman, A.1    Otero, J.2    Brizolara, A.3
  • 80
    • 26244453309 scopus 로고    scopus 로고
    • Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): A randomised controlled trial
    • Dormandy JA, Charbonnel B, Eckland DJ, et al: Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet 2005; 366: 1279-1289.
    • (2005) Lancet , vol.366 , pp. 1279-1289
    • Dormandy, J.A.1    Charbonnel, B.2    Eckland, D.J.3
  • 81
    • 24944569269 scopus 로고    scopus 로고
    • Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes (RECORD): Study design and protocol
    • Home PD, Pocock SJ, Beck-Nielsen H, et al: Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes (RECORD): study design and protocol. Diabetologia 2005; 48: 1726-1735.
    • (2005) Diabetologia , vol.48 , pp. 1726-1735
    • Home, P.D.1    Pocock, S.J.2    Beck-Nielsen, H.3
  • 82
    • 0032934104 scopus 로고    scopus 로고
    • Kelly IE, Han TS, Walsh K, et al: Effects of a thiazolidinedione compound on body fat and fat distribution of patients with type 2 diabetes. Diabetes Care 1999; 22: 288-293. Erratum in: Diabetes Care 1999; 22: 536.
    • Kelly IE, Han TS, Walsh K, et al: Effects of a thiazolidinedione compound on body fat and fat distribution of patients with type 2 diabetes. Diabetes Care 1999; 22: 288-293. Erratum in: Diabetes Care 1999; 22: 536.
  • 83
    • 0034750654 scopus 로고    scopus 로고
    • Thiazolidinedione derivative improves fat distribution and multiple risk factors in subjects with visceral fat accumulation: Double-blind placebo-controlled trial
    • Nakamura T, Funahashi T, Yamashita S, et al: Thiazolidinedione derivative improves fat distribution and multiple risk factors in subjects with visceral fat accumulation: double-blind placebo-controlled trial. Diabetes Res Clin Pract 2001; 54: 181-190.
    • (2001) Diabetes Res Clin Pract , vol.54 , pp. 181-190
    • Nakamura, T.1    Funahashi, T.2    Yamashita, S.3
  • 84
    • 0032806041 scopus 로고    scopus 로고
    • Troglitazone inhibits bicarbonate secretion in rat and human duodenum
    • Hosokawa M, Tsukada H, Fukuda K, et al: Troglitazone inhibits bicarbonate secretion in rat and human duodenum. J Pharmacol Exp Ther 1999; 290: 1080-1084.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 1080-1084
    • Hosokawa, M.1    Tsukada, H.2    Fukuda, K.3
  • 85
    • 0344304678 scopus 로고    scopus 로고
    • Thiazolidinedione use, fluid retention, and congestive heart failure
    • Nesto RW, Bell D, Bonow R, et al: Thiazolidinedione use, fluid retention, and congestive heart failure. Circulation 2003; 108: 2941-2948.
    • (2003) Circulation , vol.108 , pp. 2941-2948
    • Nesto, R.W.1    Bell, D.2    Bonow, R.3
  • 86
    • 0032972793 scopus 로고    scopus 로고
    • Hemodynamic basis for the acute cardiac effects of troglitazone in isolated perfused rat hearts
    • Shimoyama M, Ogino K, Tanaka Y, et al: Hemodynamic basis for the acute cardiac effects of troglitazone in isolated perfused rat hearts. Diabetes 1999; 48: 609-615.
    • (1999) Diabetes , vol.48 , pp. 609-615
    • Shimoyama, M.1    Ogino, K.2    Tanaka, Y.3
  • 87
    • 0031054699 scopus 로고    scopus 로고
    • Cardiac and glycemic benefits of troglitazone treatment in NIDDM. The Troglitazone Study Group
    • Ghazzi MN, Perez JE, Antonucci TK, et al: Cardiac and glycemic benefits of troglitazone treatment in NIDDM. The Troglitazone Study Group. Diabetes 1997; 46: 433-439.
    • (1997) Diabetes , vol.46 , pp. 433-439
    • Ghazzi, M.N.1    Perez, J.E.2    Antonucci, T.K.3
  • 88
    • 0000362564 scopus 로고    scopus 로고
    • Long-term echocardiographic assessment in patients with type 2 diabetes mellitus treated with pioglitazone
    • Schneider RL, Shaffer SJ: Long-term echocardiographic assessment in patients with type 2 diabetes mellitus treated with pioglitazone. Diabetes 2000; 49(Suppl 1): A124.
    • (2000) Diabetes , vol.49 , Issue.SUPPL. 1
    • Schneider, R.L.1    Shaffer, S.J.2
  • 89
    • 0035923566 scopus 로고    scopus 로고
    • In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone
    • Yue TL, Chen J, Bao W: In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone. Circulation 2001; 104: 2588-2594.
    • (2001) Circulation , vol.104 , pp. 2588-2594
    • Yue, T.L.1    Chen, J.2    Bao, W.3
  • 90
    • 0037058874 scopus 로고    scopus 로고
    • Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction
    • Shiomi T, Tsutsui H, Hayashidani S, et al: Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction. Circulation 2002; 106: 3126 3132.
    • (2002) Circulation , vol.106 , pp. 3126-3132
    • Shiomi, T.1    Tsutsui, H.2    Hayashidani, S.3
  • 91
    • 0035103716 scopus 로고    scopus 로고
    • Pulmonary edema associated with rosiglitazone and troglitazone
    • Thomas ML, Lloyd SJ: Pulmonary edema associated with rosiglitazone and troglitazone. Ann Pharmacother 2001; 35: 123-124.
    • (2001) Ann Pharmacother , vol.35 , pp. 123-124
    • Thomas, M.L.1    Lloyd, S.J.2
  • 92
    • 0033598091 scopus 로고    scopus 로고
    • Pulmonary edema associated with troglitazone therapy
    • Hirsch IB, Kelly J, Cooper S: Pulmonary edema associated with troglitazone therapy. Arch Intern Med 1999; 159: 1811.
    • (1999) Arch Intern Med , vol.159 , pp. 1811
    • Hirsch, I.B.1    Kelly, J.2    Cooper, S.3
  • 93
    • 0037393015 scopus 로고    scopus 로고
    • Fluid retention after initiation of thiazolidinedione therapy in diabetic patients with established chronic heart failure
    • Tang WH, Francis GS, Hoogwerf BJ, et al: Fluid retention after initiation of thiazolidinedione therapy in diabetic patients with established chronic heart failure. J Am Coll Cardiol 2003; 41: 1394-1398.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1394-1398
    • Tang, W.H.1    Francis, G.S.2    Hoogwerf, B.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.