-
1
-
-
0033948368
-
Repertoire selection by pre-B-cell receptors and B-cell receptors, and genetic control of B-cell development from immature to mature B cells
-
Melchers F, ten Boekel E, Seidl T, et al. Repertoire selection by pre-B-cell receptors and B-cell receptors, and genetic control of B-cell development from immature to mature B cells. Immunol Rev. 2000;175:33-46.
-
(2000)
Immunol Rev
, vol.175
, pp. 33-46
-
-
Melchers, F.1
ten Boekel, E.2
Seidl, T.3
-
3
-
-
0030006070
-
Clonal selection and learning in the antibody system
-
Rajewsky K. Clonal selection and learning in the antibody system. Nature. 1996;381:751-758.
-
(1996)
Nature
, vol.381
, pp. 751-758
-
-
Rajewsky, K.1
-
4
-
-
0026583842
-
Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion
-
Kitamura D, Rajewsky K. Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion. Nature. 1992;356:154-156.
-
(1992)
Nature
, vol.356
, pp. 154-156
-
-
Kitamura, D.1
Rajewsky, K.2
-
5
-
-
0026652354
-
A critical role of lambda 5 protein in B cell development
-
Kitamura D, Kudo A, Schaal S, et al. A critical role of lambda 5 protein in B cell development. Cell. 1992;69:823-831.
-
(1992)
Cell
, vol.69
, pp. 823-831
-
-
Kitamura, D.1
Kudo, A.2
Schaal, S.3
-
6
-
-
0035910752
-
Loss of precursor B cell expansion but not allelic exclusion in VpreB1/VpreB2 double-deficient mice
-
Mundt C, Licence S, Shimizu T, Melchers F, Martensson IL. Loss of precursor B cell expansion but not allelic exclusion in VpreB1/VpreB2 double-deficient mice. J Exp Med. 2001;193:435-445.
-
(2001)
J Exp Med
, vol.193
, pp. 435-445
-
-
Mundt, C.1
Licence, S.2
Shimizu, T.3
Melchers, F.4
Martensson, I.L.5
-
7
-
-
0030058466
-
Aberrant B cell development and immune response in mice with a compromised BCR complex
-
Torres RM, Flaswinkel H, Reth M, Rajewsky K. Aberrant B cell development and immune response in mice with a compromised BCR complex. Science. 1996;272:1804-1808.
-
(1996)
Science
, vol.272
, pp. 1804-1808
-
-
Torres, R.M.1
Flaswinkel, H.2
Reth, M.3
Rajewsky, K.4
-
8
-
-
0030468487
-
Counterselection against D mu is mediated through immunoglobulin (Ig)alpha-Igbeta
-
Gong S, Sanchez M, Nussenzweig MC. Counterselection against D mu is mediated through immunoglobulin (Ig)alpha-Igbeta. J Exp Med. 1996;184:2079-2084.
-
(1996)
J Exp Med
, vol.184
, pp. 2079-2084
-
-
Gong, S.1
Sanchez, M.2
Nussenzweig, M.C.3
-
9
-
-
0033010661
-
Genetic analysis of B cell antigen receptor signaling
-
Kurosaki T. Genetic analysis of B cell antigen receptor signaling. Annu Rev Immunol. 1999;17:555-592.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 555-592
-
-
Kurosaki, T.1
-
10
-
-
0033025948
-
Signal transduction from the B cell antigen-receptor
-
Campbell KS. Signal transduction from the B cell antigen-receptor. Curr Opin Immunol. 1999;11:256-264.
-
(1999)
Curr Opin Immunol
, vol.11
, pp. 256-264
-
-
Campbell, K.S.1
-
11
-
-
0033959733
-
BLNK: Connecting Syk and Btk to calcium signals
-
Kurosaki T, Tsukada S. BLNK: connecting Syk and Btk to calcium signals. Immunity. 2000;12:1-5.
-
(2000)
Immunity
, vol.12
, pp. 1-5
-
-
Kurosaki, T.1
Tsukada, S.2
-
14
-
-
0028889302
-
Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase
-
Turner M, Mee PJ, Costello PS, et al. Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk. Nature. 1995;378:298-302.
-
(1995)
Syk. Nature
, vol.378
, pp. 298-302
-
-
Turner, M.1
Mee, P.J.2
Costello, P.S.3
-
15
-
-
0028783322
-
Syk tyrosine kinase required for mouse viability and B-cell development
-
Cheng AM, Rowley B, Pao W, et al. Syk tyrosine kinase required for mouse viability and B-cell development. Nature. 1995;378:303-306.
-
(1995)
Nature
, vol.378
, pp. 303-306
-
-
Cheng, A.M.1
Rowley, B.2
Pao, W.3
-
16
-
-
0037234971
-
The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion
-
Flemming A, Brummer T, Reth M, Jumaa H. The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion. Nat Immunol. 2003;4:38-43.
-
(2003)
Nat Immunol
, vol.4
, pp. 38-43
-
-
Flemming, A.1
Brummer, T.2
Reth, M.3
Jumaa, H.4
-
17
-
-
0037805640
-
Distinct signaling requirements for Dmu selection, IgH allelic exclusion, pre-B cell transition, and tumor suppression in B cell progenitors
-
Hayashi K, Yamamoto M, Nojima T, Goitsuka R, Kitamura D. Distinct signaling requirements for Dmu selection, IgH allelic exclusion, pre-B cell transition, and tumor suppression in B cell progenitors. Immunity. 2003;18:825-836.
-
(2003)
Immunity
, vol.18
, pp. 825-836
-
-
Hayashi, K.1
Yamamoto, M.2
Nojima, T.3
Goitsuka, R.4
Kitamura, D.5
-
18
-
-
0034932149
-
The absence of SLP65 and Btk blocks B cell development at the preB cell receptor-positive stage
-
Jumaa H, Mitterer M, Reth M, Nielsen PJ. The absence of SLP65 and Btk blocks B cell development at the preB cell receptor-positive stage. Eur J Immunol. 2001;31:2164-2169.
-
(2001)
Eur J Immunol
, vol.31
, pp. 2164-2169
-
-
Jumaa, H.1
Mitterer, M.2
Reth, M.3
Nielsen, P.J.4
-
19
-
-
33645756083
-
Phospholipase C{gamma}2 dosage is critical for B cell development in the absence of adaptor protein BLNK
-
Xu S, Huo J, Chew WK, et al. Phospholipase C{gamma}2 dosage is critical for B cell development in the absence of adaptor protein BLNK. J Immunol. 2006;176:4690-4698.
-
(2006)
J Immunol
, vol.176
, pp. 4690-4698
-
-
Xu, S.1
Huo, J.2
Chew, W.K.3
-
20
-
-
0030018304
-
A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2
-
Takata M, Kurosaki T. A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2. J Exp Med. 1996;184:31-40.
-
(1996)
J Exp Med
, vol.184
, pp. 31-40
-
-
Takata, M.1
Kurosaki, T.2
-
21
-
-
0032055476
-
Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation
-
Fluckiger AC, Li Z, Kato RM, et al. Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation. EMBO J. 1998;17:1973-1985.
-
(1998)
EMBO J
, vol.17
, pp. 1973-1985
-
-
Fluckiger, A.C.1
Li, Z.2
Kato, R.M.3
-
22
-
-
0345138995
-
BTK regulates PtdIns-4,5-P2 synthesis: Importance for calcium signaling and PI3K activity
-
Saito K, Tolias KF, Saci A, et al. BTK regulates PtdIns-4,5-P2 synthesis: importance for calcium signaling and PI3K activity. Immunity. 2003;19:669-678.
-
(2003)
Immunity
, vol.19
, pp. 669-678
-
-
Saito, K.1
Tolias, K.F.2
Saci, A.3
-
23
-
-
0024849618
-
Analysis of signaling via surface immunoglobulin receptors on B cells from CBA/N mice
-
Rigley KP, Harnett MM, Phillips RJ, Klaus GG. Analysis of signaling via surface immunoglobulin receptors on B cells from CBA/N mice. Eur J Immunol. 1989;19:2081-2086.
-
(1989)
Eur J Immunol
, vol.19
, pp. 2081-2086
-
-
Rigley, K.P.1
Harnett, M.M.2
Phillips, R.J.3
Klaus, G.G.4
-
24
-
-
0034663761
-
Cutting edge: Essential role of phospholipase C-gamma 2 in B cell development and function
-
Hashimoto A, Takeda K, Inaba M, et al. Cutting edge: essential role of phospholipase C-gamma 2 in B cell development and function. J Immunol. 2000;165:1738-1742.
-
(2000)
J Immunol
, vol.165
, pp. 1738-1742
-
-
Hashimoto, A.1
Takeda, K.2
Inaba, M.3
-
25
-
-
0033624638
-
Phospholipase Cgamma2 is essential in the functions of B cell and several Fc receptors
-
Wang D, Feng J, Wen R, et al. Phospholipase Cgamma2 is essential in the functions of B cell and several Fc receptors. Immunity. 2000;13:25-35.
-
(2000)
Immunity
, vol.13
, pp. 25-35
-
-
Wang, D.1
Feng, J.2
Wen, R.3
-
26
-
-
0034657307
-
Bruton's tyrosine kinase is required for activation of IkappaB kinase and nuclear factor kappaB in response to B cell receptor engagement
-
Petro JB, Rahman SM, Ballard DW, Khan WN. Bruton's tyrosine kinase is required for activation of IkappaB kinase and nuclear factor kappaB in response to B cell receptor engagement. J Exp Med. 2000;191:1745-1754.
-
(2000)
J Exp Med
, vol.191
, pp. 1745-1754
-
-
Petro, J.B.1
Rahman, S.M.2
Ballard, D.W.3
Khan, W.N.4
-
27
-
-
0034657235
-
Bruton's tyrosine kinase links the B cell receptor to nuclear factor kappaB activation
-
Bajpai UD, Zhang K, Teutsch M, Sen R, Wortis HH. Bruton's tyrosine kinase links the B cell receptor to nuclear factor kappaB activation. J Exp Med. 2000;191:1735-1744.
-
(2000)
J Exp Med
, vol.191
, pp. 1735-1744
-
-
Bajpai, U.D.1
Zhang, K.2
Teutsch, M.3
Sen, R.4
Wortis, H.H.5
-
28
-
-
0042922816
-
Coupling between B cell receptor and phospholipase C-gamma2 is essential for mature B cell development
-
Hikida M, Johmura S, Hashimoto A, Takezaki M, Kurosaki T. Coupling between B cell receptor and phospholipase C-gamma2 is essential for mature B cell development. J Exp Med. 2003;198:581-589.
-
(2003)
J Exp Med
, vol.198
, pp. 581-589
-
-
Hikida, M.1
Johmura, S.2
Hashimoto, A.3
Takezaki, M.4
Kurosaki, T.5
-
29
-
-
0028847330
-
Impaired expansion of mouse B cell progenitors lacking
-
Kerner JD, Appleby MW, Mohr RN, et al. Impaired expansion of mouse B cell progenitors lacking Btk. Immunity. 1995;3:301-312.
-
(1995)
Btk. Immunity
, vol.3
, pp. 301-312
-
-
Kerner, J.D.1
Appleby, M.W.2
Mohr, R.N.3
-
30
-
-
0028847329
-
Defective B cell development and function in Btk-deficient mice
-
Khan WN, Alt FW, Gerstein RM, et al. Defective B cell development and function in Btk-deficient mice. Immunity. 1995;3:283-299.
-
(1995)
Immunity
, vol.3
, pp. 283-299
-
-
Khan, W.N.1
Alt, F.W.2
Gerstein, R.M.3
-
31
-
-
0029792213
-
Inactivation of Btk by insertion of lacZ reveals defects in B cell development only past the pre-B cell stage
-
Hendriks RW, de Bruijn MF, Maas A, et al. Inactivation of Btk by insertion of lacZ reveals defects in B cell development only past the pre-B cell stage. EMBO J. 1996;15:4862-4872.
-
(1996)
EMBO J
, vol.15
, pp. 4862-4872
-
-
Hendriks, R.W.1
de Bruijn, M.F.2
Maas, A.3
-
32
-
-
0034090263
-
B cell development and activation defects resulting in xid-like immunodeficiency in BLNK/SLP-65-deficient mice
-
Xu S, Tan JE, Wong EP, et al. B cell development and activation defects resulting in xid-like immunodeficiency in BLNK/SLP-65-deficient mice. Int Immunol. 2000;12:397-404.
-
(2000)
Int Immunol
, vol.12
, pp. 397-404
-
-
Xu, S.1
Tan, J.E.2
Wong, E.P.3
-
33
-
-
0342711256
-
In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
-
Lam KP, Kuhn R, Rajewsky K. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell. 1997;90:1073-1083.
-
(1997)
Cell
, vol.90
, pp. 1073-1083
-
-
Lam, K.P.1
Kuhn, R.2
Rajewsky, K.3
-
34
-
-
0034667788
-
-
Xu S, Wong SC, Lam KP. Cutting edge: B cell linker protein is dispensable for the allelic exclusion of immunoglobulin heavy chain locus but required for the persistence of CD5+ B cells. J Immunol. 2000;165:4153-4157.
-
Xu S, Wong SC, Lam KP. Cutting edge: B cell linker protein is dispensable for the allelic exclusion of immunoglobulin heavy chain locus but required for the persistence of CD5+ B cells. J Immunol. 2000;165:4153-4157.
-
-
-
-
35
-
-
0035911235
-
Insertion of phosphoglycerine kinase (PGK)-neo 5' of Jlambda1 dramatically enhances VJlambda1 rearrangement
-
Sun T, Storb U. Insertion of phosphoglycerine kinase (PGK)-neo 5' of Jlambda1 dramatically enhances VJlambda1 rearrangement. J Exp Med. 2001;193:699-712.
-
(2001)
J Exp Med
, vol.193
, pp. 699-712
-
-
Sun, T.1
Storb, U.2
-
36
-
-
25444448196
-
Cbp deficiency alters Csk localization in lipid rafts but does not affect T-cell development
-
Xu S, Huo J, Tan JE, Lam KP. Cbp deficiency alters Csk localization in lipid rafts but does not affect T-cell development. Mol Cell Biol. 2005;25:8486-8495.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8486-8495
-
-
Xu, S.1
Huo, J.2
Tan, J.E.3
Lam, K.P.4
-
38
-
-
0035927178
-
Bruton's tyrosine kinase regulates the activation of gene rearrangements at the lambda light chain locus in precursor B cells in the mouse
-
Dingjan GM, Middendorp S, Dahlenborg K et al. Bruton's tyrosine kinase regulates the activation of gene rearrangements at the lambda light chain locus in precursor B cells in the mouse. J Exp Med. 2001;193:1169-1178.
-
(2001)
J Exp Med
, vol.193
, pp. 1169-1178
-
-
Dingjan, G.M.1
Middendorp, S.2
Dahlenborg, K.3
-
39
-
-
0026011211
-
Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo
-
Rolink A, Kudo A, Karasuyama H, Kikuchi Y, Melchers F. Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo. EMBO J. 1991;10:327-336.
-
(1991)
EMBO J
, vol.10
, pp. 327-336
-
-
Rolink, A.1
Kudo, A.2
Karasuyama, H.3
Kikuchi, Y.4
Melchers, F.5
-
40
-
-
0034748389
-
Pre-B cell receptor signaling mediates selective response to IL-7 at the pro-B to pre-B cell transition via an ERK/MAP kinase-dependent pathway
-
Fleming HE, Paige CJ. Pre-B cell receptor signaling mediates selective response to IL-7 at the pro-B to pre-B cell transition via an ERK/MAP kinase-dependent pathway. Immunity. 2001;15:521-531.
-
(2001)
Immunity
, vol.15
, pp. 521-531
-
-
Fleming, H.E.1
Paige, C.J.2
-
41
-
-
0033030727
-
Signal transduction pathways that regulate the fate of B lymphocytes
-
Craxton A, Otipoby KL, Jiang A, Clark EA. Signal transduction pathways that regulate the fate of B lymphocytes. Adv Immunol. 1999;73:79-152.
-
(1999)
Adv Immunol
, vol.73
, pp. 79-152
-
-
Craxton, A.1
Otipoby, K.L.2
Jiang, A.3
Clark, E.A.4
-
42
-
-
0026729146
-
Predominant expression and activation-induced tyrosine phosphorylation of phospholipase C-gamma 2 in B lymphocytes
-
Coggeshall KM, McHugh JC, Altman A. Predominant expression and activation-induced tyrosine phosphorylation of phospholipase C-gamma 2 in B lymphocytes. Proc Natl Acad Sci U S A. 1992;89:5660-5664.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 5660-5664
-
-
Coggeshall, K.M.1
McHugh, J.C.2
Altman, A.3
-
43
-
-
0026558040
-
Phospholipase C-gamma 1 and phospholipase C-gamma 2 are substrates of the B cell antigen receptor associated protein tyrosine kinase
-
Roifman CM, Wang G. Phospholipase C-gamma 1 and phospholipase C-gamma 2 are substrates of the B cell antigen receptor associated protein tyrosine kinase. Biochem Biophys Res Commun. 1992;183:411-416.
-
(1992)
Biochem Biophys Res Commun
, vol.183
, pp. 411-416
-
-
Roifman, C.M.1
Wang, G.2
-
44
-
-
8144221736
-
An important role of phospholipase Cgamma1 in pre-B-cell development and allelic exclusion
-
Wen R, Chen Y, Schuman J, et al. An important role of phospholipase Cgamma1 in pre-B-cell development and allelic exclusion. EMBO J. 2004;23:4007-4017.
-
(2004)
EMBO J
, vol.23
, pp. 4007-4017
-
-
Wen, R.1
Chen, Y.2
Schuman, J.3
-
45
-
-
4444336336
-
Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker
-
Humphries LA, Dangelmaier C, Sommer K, et al. Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker. J Biol Chem. 2004;279:37651-37661.
-
(2004)
J Biol Chem
, vol.279
, pp. 37651-37661
-
-
Humphries, L.A.1
Dangelmaier, C.2
Sommer, K.3
-
46
-
-
0025805394
-
PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254
-
Kim HK, Kim JW, Zilberstein A, et al. PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254. Cell. 1991;65:435-441.
-
(1991)
Cell
, vol.65
, pp. 435-441
-
-
Kim, H.K.1
Kim, J.W.2
Zilberstein, A.3
-
47
-
-
0023189116
-
Allelic exclusion in transgenic mice that express the membrane form of immunoglobulin mu
-
Nussenzweig MC, Shaw AC, Sinn E, et al. Allelic exclusion in transgenic mice that express the membrane form of immunoglobulin mu. Science. 1987;236:816-819.
-
(1987)
Science
, vol.236
, pp. 816-819
-
-
Nussenzweig, M.C.1
Shaw, A.C.2
Sinn, E.3
-
48
-
-
0037815206
-
Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells
-
Kersseboom R, Middendorp S, Dingjan GM, et al. Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells. J Exp Med. 2003;198:91-98.
-
(2003)
J Exp Med
, vol.198
, pp. 91-98
-
-
Kersseboom, R.1
Middendorp, S.2
Dingjan, G.M.3
-
49
-
-
0026583842
-
Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion
-
Kitamura D, Rajewsky K. Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion. Nature. 1992;356:154-156.
-
(1992)
Nature
, vol.356
, pp. 154-156
-
-
Kitamura, D.1
Rajewsky, K.2
-
50
-
-
0037396717
-
Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion
-
Schweighoffer E, Vanes L, Mathiot A, Nakamura T, Tybulewicz VL. Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion. Immunity. 2003;18:523-533.
-
(2003)
Immunity
, vol.18
, pp. 523-533
-
-
Schweighoffer, E.1
Vanes, L.2
Mathiot, A.3
Nakamura, T.4
Tybulewicz, V.L.5
|