AKT induces senescence in primary esophageal epithelial cells but is permissive for differentiation as revealed in organotypic culture

Oncogene

Volumn 26, Issue 16, 2007, Pages 2353-2364

  Oyama, K ^a   Okawa, T ^a   Nakagawa, H ^a   Takaoka, M ^a   Andl, C D ^a   Kim, S H ^a   Klein Szanto, A ^b   Diehl, J A ^c   Herlyn, M ^a   El Deiry, W ^a,c   Rustgi, A K ^a,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b FOX CHASE CANCER CENTER   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

AKT; Differentiation; EGFR; Organotypic culture; Proliferation

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ARTICLE; CELL CULTURE; CELL GROWTH; CELL IMMORTALIZATION; CELL SHAPE; CELL SIZE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME INHIBITION; EPITHELIUM HYPERPLASIA; ESOPHAGUS MUCOSA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CELL AGING; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; EPITHELIAL CELLS; ESOPHAGUS; GENETIC VECTORS; HUMANS; IMMUNOHISTOCHEMISTRY; ONCOGENE PROTEIN V-AKT; ORGAN CULTURE TECHNIQUES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RETROVIRIDAE;

EID: 34147150218     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210025     Document Type: Article

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